Blockade of TGF-β by catheter-based local intravascular gene delivery does not alter the in-stent neointimal response, but enhances inflammation in pig coronary arteries

International Journal of Cardiology

Volumn 145, Issue 3, 2010, Pages 468-475

  Chung, Ick Mo ^a   Kim, Junwoo ^b   Pak, Youngmi K ^c   Jang, Yangsoo ^d   Yang, Woo Ick ^d   Han, Innoc ^e   Park, Seung Jung ^f   Park, Seong Wook ^f   Huh, Jooryung ^f   Wight, Thomas N ^g   Ueno, Hikaru ^h  

^a Ewha Womans University School of Medicine   (South Korea)

^b Korea National Institute of Health   (South Korea)

^c Kyung Hee University Hospital   (South Korea)

^d Yonsei University College of Medicine   (South Korea)

^e Inha University School of Medicine   (South Korea)

^f University of Ulsan College of Medicine   (South Korea)

^g BENAROYA RESEARCH INSTITUTE   (United States)

^h UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

Hyaluronan; Inflammation; Restenosis; Stents; Transforming growth factor

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; CONNECTIVE TISSUE GROWTH FACTOR; HYALURONIC ACID; INTERSTITIAL COLLAGENASE; MESSENGER RNA; PHOSPHATE BUFFERED SALINE; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD3+ T LYMPHOCYTE; CELL DENSITY; CELL PROLIFERATION; CONTROLLED STUDY; CORONARY ARTERY; CORONARY STENT; EXTRACELLULAR MATRIX; FEMALE; HISTOPATHOLOGY; IN-STENT RESTENOSIS; INFLAMMATORY CELL; INTRAVASCULAR CATHETER; LYMPHOCYTIC INFILTRATION; MALE; MORPHOMETRICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER; SWINE; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY;

ANGIOPLASTY; ANIMALS; ANTIGENS, CD3; CATHETERIZATION; CELLS, CULTURED; CONNECTIVE TISSUE GROWTH FACTOR; CORONARY ARTERY DISEASE; FEMALE; GENE TRANSFER TECHNIQUES; HYALURONIC ACID; MALE; MATRIX METALLOPROTEINASE 1; MUSCLE, SMOOTH, VASCULAR; NEOINTIMA; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; STENTS; SWINE; T-LYMPHOCYTES; TRANSFORMING GROWTH FACTOR BETA;

EID: 78149349800     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijcard.2009.11.032     Document Type: Article

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