Blockade of TGF-β by in vivo gene transfer of a soluble TGF-β type II receptor in the muscle inhibits corneal opacification, edema and angiogenesis

Gene Therapy

Volumn 7, Issue 22, 2000, Pages 1915-1924

  Sakamoto, T ^a   Ueno, H ^a   Sonoda, K ^a   Hisatomi, T ^a   Shimizu, K ^b   Ohashi, H ^b   Inomata, H ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b KIRIN BREWERY CO LTD   (Japan)

Author keywords

Adenovirus; Cornea; Gene therapy; Soluble TGF receptor; TGF

Indexed keywords

BETA GALACTOSIDASE; FIBRONECTIN; IMMUNOGLOBULIN FC FRAGMENT; MONOCYTE CHEMOTACTIC PROTEIN 1; RECEPTOR PROTEIN; SILVER NITRATE; SODIUM CHLORIDE; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; VASCULOTROPIN; VIRUS VECTOR;

ADENOVIRUS; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AQUEOUS HUMOR; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; CORNEA EDEMA; CORNEA INJURY; CORNEA OPACITY; CORNEA VASCULARIZATION; EXTRACELLULAR MATRIX; FEMUR; GENE CONSTRUCT; GENE EXPRESSION; GENE FUSION; GENE THERAPY; GENE TRANSFER; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MONOCYTE; MOUSE; MOUSE STRAIN; MUSCLE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RECEPTOR SOLUBILIZATION; SIGNAL TRANSDUCTION;

ADENOVIRIDAE; ANIMALIA;

EID: 0033670587     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301320     Document Type: Article

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