메뉴 건너뛰기




Volumn 11, Issue 10, 2010, Pages 1403-1425

Compilation of a comprehensive gene panel for systematic assessment of genes that govern an individuals drug responses

Author keywords

adverse drug reaction; efficacy n GWAS; pharmacodynamics; pharmacogenomics; pharmacokinetics

Indexed keywords

ABC TRANSPORTER; ACYL COENZYME A DEHYDROGENASE; ALDO KETO REDUCTASE; AMIDASE; AMINE OXIDASE (FLAVIN CONTAINING); ARACHIDONATE LIPOXYGENASE; BINDING PROTEIN; CARBONYL REDUCTASE; CYTOCHROME P450; EPOXIDE HYDROLASE; FLAVOPROTEIN; FLAVOPROTEIN PYRIDINE NUCLEOTIDE CYTOCHROME REDUCTASE; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; HYDROXYSTEROID DEHYDROGENASE; MICRORNA; OXIDOREDUCTASE; PEROXIDASE; PROSTAGLANDIN SYNTHASE; PROTEIN FMO; PROTEIN MT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); RIBONUCLEOSIDE; RIBONUCLEOSIDE DISPHOSPHATE REDUCTASE; SECONDARY LYMPHOID TISSUE CHEMOKINE; STEROID 5ALPHA REDUCTASE; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE; VASOPRESSIN; XENOBIOTIC AGENT;

EID: 78149348145     PISSN: 14622416     EISSN: 17448042     Source Type: Journal    
DOI: 10.2217/pgs.10.99     Document Type: Article
Times cited : (13)

References (88)
  • 1
    • 0035775486 scopus 로고    scopus 로고
    • Pharmacogenomics: The inherited basis for interindividual differences in drug response
    • Evans WE, Johnson JA: Pharmacogenomics: the inherited basis for interindividual differences in drug response. Annu. Rev. Genomics Hum. Genet. 2, 9-39 (2001).
    • (2001) Annu. Rev. Genomics Hum. Genet. , vol.2 , pp. 9-39
    • Evans, W.E.1    Johnson, J.A.2
  • 2
    • 2942597859 scopus 로고    scopus 로고
    • 'Irinogenetics' and UGT1A: From genotypes to haplotypes
    • Innocenti F, Ratain MJ: 'Irinogenetics' and UGT1A: from genotypes to haplotypes. Clin. Pharmacol. Ther. 75(6), 495-500 (2004).
    • (2004) Clin. Pharmacol. Ther. , vol.75 , Issue.6 , pp. 495-500
    • Innocenti, F.1    Ratain, M.J.2
  • 3
    • 74549176572 scopus 로고    scopus 로고
    • KRAS mutational status as a predictor of epidermal growth factor receptor inhibitor effcacy in colorectal cancer
    • Baynes RD, Gansert J: KRAS mutational status as a predictor of epidermal growth factor receptor inhibitor effcacy in colorectal cancer. Am. J. Ther. 16(6), 554-561 (2009).
    • (2009) Am. J. Ther. , vol.16 , Issue.6 , pp. 554-561
    • Baynes, R.D.1    Gansert, J.2
  • 4
    • 0030819215 scopus 로고    scopus 로고
    • Basic concepts of pharmacokinetic/pharmacodynamic (PK/PD) modelling
    • Meibohm B, Derendorf H. Basic concepts of pharmacokinetic/pharmacodynamic (PK/PD) modelling. Int. J. Clin. Pharmacol. Ther. 35(10), 401-413 (1997).
    • (1997) Int. J. Clin. Pharmacol. Ther. , vol.35 , Issue.10 , pp. 401-413
    • Meibohm, B.1    Derendorf, H.2
  • 8
    • 73349102140 scopus 로고    scopus 로고
    • Epidermal growth factor receptor inhibitors in cancer treatment: Advances, challenges and opportunities
    • Modjtahedi H, Essapen S: Epidermal growth factor receptor inhibitors in cancer treatment: advances, challenges and opportunities. Anticancer Drugs 20(10), 851-855 (2009).
    • (2009) Anticancer Drugs , vol.20 , Issue.10 , pp. 851-855
    • Modjtahedi, H.1    Essapen, S.2
  • 9
    • 0036088113 scopus 로고    scopus 로고
    • PharmGKB: The pharmacogenetics knowledge base
    • Hewett M, Oliver DE, Rubin DL et al.: PharmGKB: the pharmacogenetics knowledge base. Nucleic Acids Res. 30(1), 163-165 (2002).
    • (2002) Nucleic Acids Res. , vol.30 , Issue.1 , pp. 163-165
    • Hewett, M.1    De, O.2    Rubin, D.L.3
  • 10
    • 42149188553 scopus 로고    scopus 로고
    • CYP4F2 genetic variant alters required warfarin dose
    • Caldwell MD, Awad T, Johnson JA et al.: CYP4F2 genetic variant alters required warfarin dose. Blood 111(8), 4106-4112 (2008).
    • (2008) Blood , vol.111 , Issue.8 , pp. 4106-4112
    • Caldwell, M.D.1    Awad, T.2    Johnson, J.A.3
  • 12
    • 34547154782 scopus 로고    scopus 로고
    • Amino acid conjugation: Contribution to the metabolism and toxicity of xenobiotic carboxylic acids
    • Knights KM, Sykes MJ, Miners JO: Amino acid conjugation: contribution to the metabolism and toxicity of xenobiotic carboxylic acids. Expert Opin. Drug Metab. Toxicol. 3(2), 159-168 (2007).
    • (2007) Expert Opin. Drug Metab. Toxicol. , vol.3 , Issue.2 , pp. 159-168
    • Knights, K.M.1    Sykes, M.J.2    Miners, J.O.3
  • 13
    • 63149164307 scopus 로고    scopus 로고
    • Metallothioneins and platinum(II) anti-tumor compounds
    • Knipp M: Metallothioneins and platinum(II) anti-tumor compounds. Curr. Med. Chem. 16(5), 522-537 (2009).
    • (2009) Curr. Med. Chem. , vol.16 , Issue.5 , pp. 522-537
    • Knipp, M.1
  • 15
    • 59149088381 scopus 로고    scopus 로고
    • The impact of microRNAs and alternative splicing in pharmacogenomics
    • Passetti F, Ferreira CG, Costa FF: The impact of microRNAs and alternative splicing in pharmacogenomics. Pharmacogenomics J. 9(1), 1-13 (2009).
    • (2009) Pharmacogenomics J. , vol.9 , Issue.1 , pp. 1-13
    • Passetti, F.1    Ferreira, C.G.2    Costa, F.F.3
  • 16
    • 0003740833 scopus 로고    scopus 로고
    • McGraw-Hill Medical; McGraw-Hill [distributor], NY, USA
    • Katzung BG: Basic & Clinical Pharmacology. McGraw-Hill Medical; McGraw-Hill [distributor], NY, USA (2007).
    • (2007) Basic & Clinical Pharmacology.
    • Katzung, B.G.1
  • 19
    • 38549151817 scopus 로고    scopus 로고
    • DrugBank: A knowledgebase for drugs, drug actions and drug targets
    • Wishart DS, Knox C, Guo AC et al.: DrugBank: a knowledgebase for drugs, drug actions and drug targets. Nucleic Acids Res. 36(Database issue), D901-D906 (2008).
    • (2008) Nucleic Acids Res. , vol.36 , Issue.DATABASE ISSUE
    • Wishart, D.S.1    Knox, C.2    Guo, A.C.3
  • 21
    • 42649111672 scopus 로고    scopus 로고
    • Evaluation of coverage variation of SNP chips for genome-wide association studies
    • Li M, Li C, Guan W: Evaluation of coverage variation of SNP chips for genome-wide association studies. Eur. J. Hum. Genet. 16(5), 635-643 (2008).
    • (2008) Eur. J. Hum. Genet. , vol.16 , Issue.5 , pp. 635-643
    • Li, M.1    Li, C.2    Guan, W.3
  • 22
    • 37749000841 scopus 로고    scopus 로고
    • Impact of lipoproteins on the biological activity and disposition of hydrophobic drugs: Implications for drug discovery
    • Wasan KM, Brocks DR, Lee SD, Sachs-Barrable K, Thornton SJ: Impact of lipoproteins on the biological activity and disposition of hydrophobic drugs: implications for drug discovery. Nat. Rev. Drug Discov. 7(1), 84-99 (2008).
    • (2008) Nat. Rev. Drug Discov. , vol.7 , Issue.1 , pp. 84-99
    • Wasan, K.M.1    Brocks, D.R.2    Lee, S.D.3    Sachs-Barrable, K.4    Thornton, S.J.5
  • 24
    • 65549121495 scopus 로고    scopus 로고
    • Human ATP-binding cassette (ABC) transporter family
    • Vasiliou V, Vasiliou K, Nebert DW: Human ATP-binding cassette (ABC) transporter family. Hum. Genomics 3(3), 281-290 (2009).
    • (2009) Hum. Genomics , vol.3 , Issue.3 , pp. 281-290
    • Vasiliou, V.1    Vasiliou, K.2    Nebert, D.W.3
  • 26
    • 34249005342 scopus 로고    scopus 로고
    • The nonABC drug transporter RLIP76 (RALBP-1) plays a major role in the mechanisms of drug resistance
    • Awasthi YC, Sharma R, Yadav S, Dwivedi S, Sharma A, Awasthi S: The nonABC drug transporter RLIP76 (RALBP-1) plays a major role in the mechanisms of drug resistance. Curr. Drug Metab. 8(4), 315-323 (2007).
    • (2007) Curr. Drug Metab. , vol.8 , Issue.4 , pp. 315-323
    • Awasthi, Y.C.1    Sharma, R.2    Yadav, S.3    Dwivedi, S.4    Sharma, A.5    Awasthi, S.6
  • 27
    • 58649124072 scopus 로고    scopus 로고
    • Roles and mechanisms of copper transporting ATPases in cancer pathogenesis
    • Zhang Y, Li M, Yao Q, Chen C: Roles and mechanisms of copper transporting ATPases in cancer pathogenesis. Med. Sci. Monit. 15(1), RA1-RA5 (2009).
    • (2009) Med. Sci. Monit. , vol.15 , Issue.1
    • Zhang, Y.1    Li, M.2    Yao, Q.3    Chen, C.4
  • 28
    • 33746035655 scopus 로고    scopus 로고
    • Translocator protein (18kDa): New nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function
    • Papadopoulos V, Baraldi M, Guilarte TR et al.: Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function. Trends Pharmacol. Sci. 27(8), 402-409 (2006).
    • (2006) Trends Pharmacol. Sci. , vol.27 , Issue.8 , pp. 402-409
    • Papadopoulos, V.1    Baraldi, M.2    Guilarte, T.R.3
  • 29
    • 33747288211 scopus 로고    scopus 로고
    • Cellular functions of vaults and their involvement in multidrug resistance
    • Steiner E, Holzmann K, Elbling L, Micksche M, Berger W: Cellular functions of vaults and their involvement in multidrug resistance. Curr. Drug Targets 7(8), 923-934 (2006).
    • (2006) Curr. Drug Targets , vol.7 , Issue.8 , pp. 923-934
    • Steiner, E.1    Holzmann, K.2    Elbling, L.3    Micksche, M.4    Berger, W.5
  • 30
    • 13844315559 scopus 로고    scopus 로고
    • CYP2C9 gene variants, drug dose, and bleeding risk in warfarin-treated patients: A HuGEnet systematic review and meta-ana lysis
    • Sanderson S, Emery J, Higgins J: CYP2C9 gene variants, drug dose, and bleeding risk in warfarin-treated patients: a HuGEnet systematic review and meta-ana lysis. Genet. Med. 7(2), 97-104 (2005).
    • (2005) Genet. Med. , vol.7 , Issue.2 , pp. 97-104
    • Sanderson, S.1    Emery, J.2    Higgins, J.3
  • 31
    • 33847034287 scopus 로고    scopus 로고
    • The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen
    • Goetz MP, Knox SK, Suman VJ et al.: The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen. Breast Cancer Res. Treat. 101(1), 113-121 (2007).
    • (2007) Breast Cancer Res. Treat. , vol.101 , Issue.1 , pp. 113-121
    • Goetz, M.P.1    Knox, S.K.2    Suman, V.J.3
  • 32
    • 58749094444 scopus 로고    scopus 로고
    • Cytochrome p-450 polymorphisms and response to clopidogrel
    • Mega JL, Close SL, Wiviott SD et al.: Cytochrome p-450 polymorphisms and response to clopidogrel. N. Engl. J. Med. 360(4), 354-362 (2009).
    • (2009) N. Engl. J. Med. , vol.360 , Issue.4 , pp. 354-362
    • Mega, J.L.1    Close, S.L.2    Wiviott, S.D.3
  • 34
    • 33747845619 scopus 로고    scopus 로고
    • The role of amine oxidases in xenobiotic metabolism
    • Gong B, Boor PJ: The role of amine oxidases in xenobiotic metabolism. Expert. Opin. Drug Metab. Toxicol. 2(4), 559-571 (2006).
    • (2006) Expert. Opin. Drug Metab. Toxicol. , vol.2 , Issue.4 , pp. 559-571
    • Gong, B.1    Boor, P.J.2
  • 35
    • 3042551383 scopus 로고    scopus 로고
    • Role of human aldehyde dehydrogenases in endobiotic and xenobiotic metabolism
    • Vasiliou V, Pappa A, Estey T: Role of human aldehyde dehydrogenases in endobiotic and xenobiotic metabolism. Drug Metab. Rev. 36(2), 279-299 (2004).
    • (2004) Drug Metab. Rev. , vol.36 , Issue.2 , pp. 279-299
    • Vasiliou, V.1    Pappa, A.2    Estey, T.3
  • 36
    • 85009625560 scopus 로고    scopus 로고
    • Drug metabolism in peroxisomes: Involvement of peroxisomal b-oxidation system in the oxidative chain-shortening of xenobiotic acyl compounds
    • Suga T: Drug metabolism in peroxisomes: involvement of peroxisomal b-oxidation system in the oxidative chain-shortening of xenobiotic acyl compounds. Drug Metab. Pharmacokinet. 18(3), 155-162 (2003).
    • (2003) Drug Metab. Pharmacokinet. , vol.18 , Issue.3 , pp. 155-162
    • Suga, T.1
  • 37
    • 0025257450 scopus 로고
    • The enzymatic basis for the metabolism and inhibitory effects of valproic acid: Dehydrogenation of valproyl-CoA by 2-methyl-branched-chain acyl-CoA dehydrogenase
    • Ito M, Ikeda Y, Arnez JG, Finocchiaro G, Tanaka K: The enzymatic basis for the metabolism and inhibitory effects of valproic acid: dehydrogenation of valproyl-CoA by 2-methyl-branched-chain acyl-CoA dehydrogenase. Biochim. Biophys. Acta. 1034(2), 213-218 (1990).
    • (1990) Biochim. Biophys. Acta. , vol.1034 , Issue.2 , pp. 213-218
    • Ito, M.1    Ikeda, Y.2    Arnez, J.G.3    Finocchiaro, G.4    Tanaka, K.5
  • 38
    • 33644749435 scopus 로고    scopus 로고
    • Inhibition of fve lipoxygenase activating protein (FLAP) by MK-886 decreases atherosclerosis in apoE/LDLR-double knockout mice
    • Jawien J, Gajda M, Rudling M et al.: Inhibition of fve lipoxygenase activating protein (FLAP) by MK-886 decreases atherosclerosis in apoE/LDLR-double knockout mice. Eur. J. Clin. Invest. 36(3), 141-146 (2006).
    • (2006) Eur. J. Clin. Invest. , vol.36 , Issue.3 , pp. 141-146
    • Jawien, J.1    Gajda, M.2    Rudling, M.3
  • 39
    • 50849141676 scopus 로고    scopus 로고
    • Glutathione peroxidase 1-defcient mice are more susceptible to doxorubicin-induced cardiotoxicity
    • Gao J, Xiong Y, Ho YS et al.: Glutathione peroxidase 1-defcient mice are more susceptible to doxorubicin-induced cardiotoxicity. Biochim. Biophys. Acta, 1783(10), 2020-2029 (2008).
    • (2008) Biochim. Biophys. Acta , vol.1783 , Issue.10 , pp. 2020-2029
    • Gao, J.1    Xiong, Y.2    Ho, Y.S.3
  • 40
    • 45849146846 scopus 로고    scopus 로고
    • Peroxidase-mediated bioactivation of hydroxylated metabolites of carbamazepine and phenytoin
    • Lu W, Uetrecht JP: Peroxidase-mediated bioactivation of hydroxylated metabolites of carbamazepine and phenytoin. Drug Metab. Dispos. 36(8), 1624-1636 (2008).
    • (2008) Drug Metab. Dispos. , vol.36 , Issue.8 , pp. 1624-1636
    • Lu, W.1    Uetrecht, J.P.2
  • 41
    • 0017195606 scopus 로고
    • Effect of antithyroid agents 6-propyl-2-thiouracil and 1-methyl-2-mercaptoimidazole on human thyroid iodine peroxidase
    • Nagasaka A, Hidaka H: Effect of antithyroid agents 6-propyl-2-thiouracil and 1-methyl-2-mercaptoimidazole on human thyroid iodine peroxidase. J. Clin. Endocrinol. Metab. 43(1), 152-158 (1976).
    • (1976) J. Clin. Endocrinol. Metab. , vol.43 , Issue.1 , pp. 152-158
    • Nagasaka, A.1    Hidaka, H.2
  • 42
    • 37249032702 scopus 로고    scopus 로고
    • IMPDH activity in thiopurine-treated patients with infammatory bowel disease-relation to TPMT activity and metabolite concentrations
    • Haglund S, Taipalensuu J, Peterson C, Almer S: IMPDH activity in thiopurine-treated patients with infammatory bowel disease-relation to TPMT activity and metabolite concentrations. Br. J. Clin. Pharmacol. 65(1), 69-77 (2008).
    • (2008) Br. J. Clin. Pharmacol. , vol.65 , Issue.1 , pp. 69-77
    • Haglund, S.1    Taipalensuu, J.2    Peterson, C.3    Almer, S.4
  • 43
    • 67651163895 scopus 로고    scopus 로고
    • Novel pharmacogenetic markers for treatment outcome in azathioprine-treated infammatory bowel disease
    • Smith MA, Marinaki AM, Arenas M et al.: Novel pharmacogenetic markers for treatment outcome in azathioprine-treated infammatory bowel disease. Aliment Pharmacol. Ther. 30(4), 375-384 (2009).
    • (2009) Aliment Pharmacol. Ther. , vol.30 , Issue.4 , pp. 375-384
    • Ma, S.1    Marinaki, A.M.2    Arenas, M.3
  • 44
    • 67651229706 scopus 로고    scopus 로고
    • Role of the MTHFR polymorphisms in cancer risk modifcation and treatment
    • Kim YI: Role of the MTHFR polymorphisms in cancer risk modifcation and treatment. Future Oncol. 5(4), 523-542 (2009).
    • (2009) Future Oncol. , vol.5 , Issue.4 , pp. 523-542
    • Kim, Y.I.1
  • 45
    • 54549110136 scopus 로고    scopus 로고
    • The aldo-keto reductase superfamily and its role in drug metabolism and detoxifcation
    • Barski OA, Tipparaju SM, Bhatnagar A: The aldo-keto reductase superfamily and its role in drug metabolism and detoxifcation. Drug Metab. Rev. 40(4), 553-624 (2008).
    • (2008) Drug Metab. Rev. , vol.40 , Issue.4 , pp. 553-624
    • Barski, O.A.1    Tipparaju, S.M.2    Bhatnagar, A.3
  • 46
    • 33846945701 scopus 로고    scopus 로고
    • Carbonyl reductases: The complex relationships of mammalian carbonyl-and quinone-reducing enzymes and their role in physiology
    • Oppermann U: Carbonyl reductases: the complex relationships of mammalian carbonyl-and quinone-reducing enzymes and their role in physiology. Annu. Rev. Pharmacol. Toxicol. 47, 293-322 (2007).
    • (2007) Annu. Rev. Pharmacol. Toxicol. , vol.47 , pp. 293-322
    • Oppermann, U.1
  • 47
    • 0036040079 scopus 로고    scopus 로고
    • N-oxidation of drugs associated with idiosyncratic drug reactions
    • Uetrecht J: N-oxidation of drugs associated with idiosyncratic drug reactions. Drug Metab. Rev. 34(3), 651-665 (2002).
    • (2002) Drug Metab. Rev. , vol.34 , Issue.3 , pp. 651-665
    • Uetrecht, J.1
  • 49
    • 35348969874 scopus 로고    scopus 로고
    • Understanding ribonucleotide reductase inactivation by gemcitabine
    • Cerqueira NM, Fernandes PA, Ramos MJ: Understanding ribonucleotide reductase inactivation by gemcitabine. Chemistry 13(30), 8507-8515 (2007).
    • (2007) Chemistry , vol.13 , Issue.30 , pp. 8507-8515
    • Cerqueira, N.M.1    Fernandes, P.A.2    Ramos, M.J.3
  • 51
    • 36048956333 scopus 로고    scopus 로고
    • Genetic variability in the cytochrome P450-paraoxonase 1 (PON1) pathway for detoxication of organophosphorus compounds
    • Furlong CE: Genetic variability in the cytochrome P450-paraoxonase 1 (PON1) pathway for detoxication of organophosphorus compounds. J. Biochem. Mol. Toxicol. 21(4), 197-205 (2007).
    • (2007) J. Biochem. Mol. Toxicol. , vol.21 , Issue.4 , pp. 197-205
    • Furlong, C.E.1
  • 52
    • 64249112966 scopus 로고    scopus 로고
    • Mammalian epoxide hydrolases in xenobiotic metabolism and signalling
    • Decker M, Arand M, Cronin A: Mammalian epoxide hydrolases in xenobiotic metabolism and signalling. Arch. Toxicol. 83(4), 297-318 (2009).
    • (2009) Arch. Toxicol. , vol.83 , Issue.4 , pp. 297-318
    • Decker, M.1    Arand, M.2    Cronin, A.3
  • 53
    • 0030751284 scopus 로고    scopus 로고
    • The role of b-glucuronidase in drug disposition and drug targeting in humans
    • Sperker B, Backman JT, Kroemer HK: The role of b-glucuronidase in drug disposition and drug targeting in humans. Clin. Pharmacokinet. 33(1), 18-31 (1997).
    • (1997) Clin. Pharmacokinet. , vol.33 , Issue.1 , pp. 18-31
    • Sperker, B.1    Backman, J.T.2    Kroemer, H.K.3
  • 54
    • 0032549068 scopus 로고    scopus 로고
    • Microsomal steroid sulfatase: Interactions with cytosolic steroid sulfotransferases
    • Kauffman FC, Sharp S, Allan BB, Burchell A, Coughtrie MW: Microsomal steroid sulfatase: interactions with cytosolic steroid sulfotransferases. Chem. Biol. Interact. 109(1-3), 169-182 (1998).
    • (1998) Chem. Biol. Interact. , vol.109 , Issue.1-3 , pp. 169-182
    • Kauffman, F.C.1    Sharp, S.2    Allan, B.B.3    Burchell, A.4    Coughtrie, M.W.5
  • 55
    • 0242312707 scopus 로고    scopus 로고
    • Drug methylation in cancer therapy: Lessons from the TPMT polymorphism
    • Krynetski E, Evans WE: Drug methylation in cancer therapy: lessons from the TPMT polymorphism. Oncogene 22(47), 7403-7413 (2003).
    • (2003) Oncogene , vol.22 , Issue.47 , pp. 7403-7413
    • Krynetski, E.1    Evans, W.E.2
  • 56
    • 0031663753 scopus 로고    scopus 로고
    • Role of hepatic fatty acid:coenzyme A ligases in the metabolism of xenobiotic carboxylic acids
    • Knights KM: Role of hepatic fatty acid:coenzyme A ligases in the metabolism of xenobiotic carboxylic acids. Clin. Exp. Pharmacol. Physiol. 25(10), 776-782 (1998).
    • (1998) Clin. Exp. Pharmacol. Physiol. , vol.25 , Issue.10 , pp. 776-782
    • Knights, K.M.1
  • 57
    • 0028998783 scopus 로고
    • Proteolysis of glucagon within hepatic endosomes by membrane-associated cathepsins B and D
    • Authier F, Mort JS, Bell AW, Posner BI, Bergeron JJ: Proteolysis of glucagon within hepatic endosomes by membrane-associated cathepsins B and D. J. Biol. Chem. 270(26), 15798-15807 (1995).
    • (1995) J. Biol. Chem. , vol.270 , Issue.26 , pp. 15798-15807
    • Authier, F.1    Mort, J.S.2    Bell, A.W.3    Posner, B.I.4    Bergeron, J.J.5
  • 58
    • 0035114992 scopus 로고    scopus 로고
    • Identifcation of insulin domains important for binding to and degradation by endosomal acidic insulinase
    • Authier F, Danielsen GM, Kouach M, Briand G, Chauvet G: Identifcation of insulin domains important for binding to and degradation by endosomal acidic insulinase. Endocrinology 142(1), 276-289 (2001).
    • (2001) Endocrinology , vol.142 , Issue.1 , pp. 276-289
    • Authier, F.1    Danielsen, G.M.2    Kouach, M.3    Briand, G.4    Chauvet, G.5
  • 59
    • 0027944370 scopus 로고
    • Effects of protease inhibitors on vasopressin transport across rat alveolar epithelial cell monolayers
    • DOI 10.1023/A:1018918022865
    • Yamahara H, Morimoto K, Lee VH, Kim KJ: Effects of protease inhibitors on vasopressin transport across rat alveolar epithelial cell monolayers. Pharm. Res. 11(11), 1617-1622 (1994). (Pubitemid 24339684)
    • (1994) Pharmaceutical Research , vol.11 , Issue.11 , pp. 1617-1622
    • Yamahara, H.1    Morimoto, K.2    Lee, V.H.L.3    Kim, K.-J.4
  • 60
    • 40949129489 scopus 로고    scopus 로고
    • Linking antibody Fc domain to endostatin signifcantly improves endostatin half-life and effcacy
    • Lee TY, Tjin Tham Sjin RM, Movahedi S et al.: Linking antibody Fc domain to endostatin signifcantly improves endostatin half-life and effcacy. Clin. Cancer Res. 14(5), 1487-1493 (2008).
    • (2008) Clin. Cancer Res. , vol.14 , Issue.5 , pp. 1487-1493
    • Lee, T.Y.1    Tjin Tham Sjin, R.M.2    Movahedi, S.3
  • 61
    • 0025063975 scopus 로고
    • Clearance of tissue plasminogen activator by mannose and galactose receptors in the liver
    • Smedsrod B, Einarsson M: Clearance of tissue plasminogen activator by mannose and galactose receptors in the liver. Thromb. Haemost. 63(1), 60-66 (1990).
    • (1990) Thromb. Haemost. , vol.63 , Issue.1 , pp. 60-66
    • Smedsrod, B.1    Einarsson, M.2
  • 62
    • 0026756089 scopus 로고
    • Low density lipoprotein receptor-related protein/a 2-macroglobulin receptor is an hepatic receptor for tissue-type plasminogen activator
    • Bu G, Williams S, Strickland DK, Schwartz AL: Low density lipoprotein receptor-related protein/a 2-macroglobulin receptor is an hepatic receptor for tissue-type plasminogen activator. Proc. Natl Acad. Sci. USA 89(16), 7427-7431 (1992).
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , Issue.16 , pp. 7427-7431
    • Bu, G.1    Williams, S.2    Strickland, D.K.3    Schwartz, A.L.4
  • 63
    • 33646531437 scopus 로고    scopus 로고
    • G proteins in drug screening: From ana lysis of receptor-G protein specifcity to manipulation of GPCR-mediated signalling pathways
    • Kostenis E: G proteins in drug screening: from ana lysis of receptor-G protein specifcity to manipulation of GPCR-mediated signalling pathways. Curr. Pharm. Des. 12(14), 1703-1715 (2006).
    • (2006) Curr. Pharm. Des. , vol.12 , Issue.14 , pp. 1703-1715
    • Kostenis, E.1
  • 65
    • 70350243205 scopus 로고    scopus 로고
    • Targeting DNA repair pathways: A novel approach to reduce cancer therapeutic resistance
    • Zhu Y, Hu J, Hu Y, Liu W: Targeting DNA repair pathways: a novel approach to reduce cancer therapeutic resistance. Cancer Treat. Rev. 35(7), 590-596 (2009).
    • (2009) Cancer Treat. Rev. , vol.35 , Issue.7 , pp. 590-596
    • Zhu, Y.1    Hu, J.2    Hu, Y.3    Liu, W.4
  • 66
    • 32944481596 scopus 로고    scopus 로고
    • Clinical course of patients with non-small cell lung cancer and epidermal growth factor receptor exon 19 and exon 21 mutations treated with geftinib or erlotinib
    • Riely GJ, Pao W, Pham D et al.: Clinical course of patients with non-small cell lung cancer and epidermal growth factor receptor exon 19 and exon 21 mutations treated with geftinib or erlotinib. Clin. Cancer Res. 12(3 Pt 1), 839-844 (2006).
    • (2006) Clin. Cancer Res. , vol.12 , Issue.3 PART 1 , pp. 839-844
    • Riely, G.J.1    Pao, W.2    Pham, D.3
  • 67
    • 68849120567 scopus 로고    scopus 로고
    • KRAS mutation testing in colorectal cancer
    • Plesec TP, Hunt JL: KRAS mutation testing in colorectal cancer. Adv. Anat. Pathol. 16(4), 196-203 (2009).
    • (2009) Adv. Anat. Pathol. , vol.16 , Issue.4 , pp. 196-203
    • Plesec, T.P.1    Hunt, J.L.2
  • 68
    • 3042729721 scopus 로고    scopus 로고
    • Oxidative stress plays an important role in the pathogenesis of drug-induced retinopathy
    • Toler SM: Oxidative stress plays an important role in the pathogenesis of drug-induced retinopathy. Exp. Biol. Med. (Maywood) 229(7), 607-615 (2004).
    • (2004) Exp. Biol. Med. (Maywood) , vol.229 , Issue.7 , pp. 607-615
    • Toler, S.M.1
  • 69
    • 9244261938 scopus 로고    scopus 로고
    • Chemotherapy-associated oxidative stress: Impact on chemotherapeutic effectiveness
    • Conklin KA: Chemotherapy-associated oxidative stress: impact on chemotherapeutic effectiveness. Integr. Cancer Ther. 3(4), 294-300 (2004).
    • (2004) Integr. Cancer Ther. , vol.3 , Issue.4 , pp. 294-300
    • Conklin, K.A.1
  • 70
    • 68349122787 scopus 로고    scopus 로고
    • Improving drug safety by locating genetic markers for hypersensitivity reactions
    • Ronaldson KJ, McNeil JJ: Improving drug safety by locating genetic markers for hypersensitivity reactions. Med. J. Aust. 190(11), 641-643 (2009).
    • (2009) Med. J. Aust. , vol.190 , Issue.11 , pp. 641-643
    • Ronaldson, K.J.1    McNeil, J.J.2
  • 72
    • 48149091056 scopus 로고    scopus 로고
    • Cellular basis of drug-induced torsades de pointes
    • Roden DM: Cellular basis of drug-induced torsades de pointes. Br. J. Pharmacol. 154(7), 1502-1507 (2008).
    • (2008) Br. J. Pharmacol. , vol.154 , Issue.7 , pp. 1502-1507
    • Roden, D.M.1
  • 73
    • 63449117825 scopus 로고    scopus 로고
    • A genome-wide association study confrms VKORC1 CYP2C9 and CYP4F2 as principal genetic determinants of warfarin dose
    • Takeuchi F, McGinnis R, Bourgeois S et al.: A genome-wide association study confrms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose. PLoS Genet. 5(3), e1000433 (2009).
    • (2009) PLoS Genet. , vol.5 , Issue.3
    • Takeuchi, F.1    McGinnis, R.2    Bourgeois, S.3
  • 74
    • 51649110496 scopus 로고    scopus 로고
    • A genome-wide scan for common genetic variants with a large infuence on warfarin maintenance dose
    • Cooper GM, Johnson JA, Langaee TY et al.: A genome-wide scan for common genetic variants with a large infuence on warfarin maintenance dose. Blood 112(4), 1022-1027 (2008).
    • (2008) Blood , vol.112 , Issue.4 , pp. 1022-1027
    • Cooper, G.M.1    Johnson, J.A.2    Langaee, T.Y.3
  • 75
    • 70350754462 scopus 로고    scopus 로고
    • A genome-wide association study of acenocoumarol maintenance dosage
    • Teichert M, Eijgelsheim M, Rivadeneira F et al.: A genome-wide association study of acenocoumarol maintenance dosage. Hum. Mol. Genet. 18(19), 3758-3768 (2009).
    • (2009) Hum. Mol. Genet. , vol.18 , Issue.19 , pp. 3758-3768
    • Teichert, M.1    Eijgelsheim, M.2    Rivadeneira, F.3
  • 76
    • 66449088323 scopus 로고    scopus 로고
    • Genome-wide association study of determinants of anti-cyclic citrullinated peptide antibody titer in adults with rheumatoid arthritis
    • Cui J, Taylor KE, Destefano AL et al.: Genome-wide association study of determinants of anti-cyclic citrullinated peptide antibody titer in adults with rheumatoid arthritis. Mol. Med. 15(5-6), 136-143 (2009).
    • (2009) Mol. Med. , vol.15 , Issue.5-6 , pp. 136-143
    • Cui, J.1    Taylor, K.E.2    Destefano, A.L.3
  • 77
    • 70349533037 scopus 로고    scopus 로고
    • Genome-wide association of IL28B with response to pegylated interferon-a and ribavirin therapy for chronic hepatitis C
    • Tanaka Y, Nishida N, Sugiyama M et al.: Genome-wide association of IL28B with response to pegylated interferon-a and ribavirin therapy for chronic hepatitis C. Nat. Genet. 41(10), 1105-1109 (2009).
    • (2009) Nat. Genet. , vol.41 , Issue.10 , pp. 1105-1109
    • Tanaka, Y.1    Nishida, N.2    Sugiyama, M.3
  • 78
    • 70349292099 scopus 로고    scopus 로고
    • Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance
    • Ge D, Fellay J, Thompson AJ et al.: Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature 461(7262), 399-401 (2009).
    • (2009) Nature , vol.461 , Issue.7262 , pp. 399-401
    • Ge, D.1    Fellay, J.2    Thompson, A.J.3
  • 79
    • 70349548852 scopus 로고    scopus 로고
    • IL28B is associated with response to chronic hepatitis C interferon-a and ribavirin therapy
    • Suppiah V, Moldovan M, Ahlenstiel G et al.: IL28B is associated with response to chronic hepatitis C interferon-a and ribavirin therapy. Nat. Genet. 41(10), 1100-1104 (2009).
    • (2009) Nat. Genet. , vol.41 , Issue.10 , pp. 1100-1104
    • Suppiah, V.1    Moldovan, M.2    Ahlenstiel, G.3
  • 80
    • 69249219296 scopus 로고    scopus 로고
    • Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical effcacy of clopidogrel therapy
    • Shuldiner AR, O'Connell JR, Bliden KP et al.: Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical effcacy of clopidogrel therapy. JAMA 302(8), 849-857 (2009).
    • (2009) JAMA , vol.302 , Issue.8 , pp. 849-857
    • Shuldiner, A.R.1    O'Connell, J.R.2    Kp, B.3
  • 81
    • 55049089081 scopus 로고    scopus 로고
    • Genome-wide association scan identifes candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis
    • Liu C, Batliwalla F, Li W et al.: Genome-wide association scan identifes candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis. Mol. Med. 14(9-10), 575-581 (2008).
    • (2008) Mol. Med. , vol.14 , Issue.9-10 , pp. 575-581
    • Liu, C.1    Batliwalla, F.2    Li, W.3
  • 82
    • 59249100224 scopus 로고    scopus 로고
    • Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia
    • Yang JJ, Cheng C, Yang W et al.: Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia. JAMA 301(4), 393-403 (2009).
    • (2009) JAMA , vol.301 , Issue.4 , pp. 393-403
    • Yang, J.J.1    Cheng, C.2    Yang, W.3
  • 83
    • 67649859295 scopus 로고    scopus 로고
    • HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to fucloxacillin
    • Daly AK, Donaldson PT, Bhatnagar P et al.: HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to fucloxacillin. Nat. Genet. 41(7), 816-819 (2009).
    • (2009) Nat. Genet. , vol.41 , Issue.7 , pp. 816-819
    • Daly, A.K.1    Donaldson, P.T.2    Bhatnagar, P.3
  • 84
    • 49949104757 scopus 로고    scopus 로고
    • SLCO1B1 variants and statin-induced myopathy-a genomewide study
    • Link E, Parish S, Armitage J et al.: SLCO1B1 variants and statin-induced myopathy-a genomewide study. N. Engl. J. Med. 359(8), 789-799 (2008).
    • (2008) N. Engl. J. Med. , vol.359 , Issue.8 , pp. 789-799
    • Link, E.1    Parish, S.2    Armitage, J.3
  • 85
    • 70350574270 scopus 로고    scopus 로고
    • Whole genome association study identifes polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia
    • Volpi S, Heaton C, Mack K et al.: Whole genome association study identifes polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia. Mol. Psychiatry 14(11), 1024-1031 (2009).
    • (2009) Mol. Psychiatry , vol.14 , Issue.11 , pp. 1024-1031
    • Volpi, S.1    Heaton, C.2    MacK, K.3
  • 86
    • 44049102035 scopus 로고    scopus 로고
    • Genome-wide pharmacogenetic investigation of a hepatic adverse event without clinical signs of immunopathology suggests an underlying immune pathogenesis
    • Kindmark A, Jawaid A, Harbron CG et al.: Genome-wide pharmacogenetic investigation of a hepatic adverse event without clinical signs of immunopathology suggests an underlying immune pathogenesis. Pharmacogenomics J. 8(3), 186-195 (2008).
    • (2008) Pharmacogenomics J. , vol.8 , Issue.3 , pp. 186-195
    • Kindmark, A.1    Jawaid, A.2    Harbron, C.G.3
  • 87
    • 53449093633 scopus 로고    scopus 로고
    • Bisphosphonate-related osteonecrosis of the jaw is associated with polymorphisms of the cytochrome P450 CYP2C8 in multiple myeloma: A genome-wide single nucleotide polymorphism ana lysis
    • Sarasquete ME, Garcia-Sanz R, Marin L et al.: Bisphosphonate-related osteonecrosis of the jaw is associated with polymorphisms of the cytochrome P450 CYP2C8 in multiple myeloma: a genome-wide single nucleotide polymorphism ana lysis. Blood 112(7), 2709-2712 (2008).
    • (2008) Blood , vol.112 , Issue.7 , pp. 2709-2712
    • Sarasquete, M.E.1    Garcia-Sanz, R.2    Marin, L.3
  • 88
    • 77950461601 scopus 로고    scopus 로고
    • Origins and functional impact of copy number variation in the human genome
    • Conrad DF, Pinto D, Redon R et al.: Origins and functional impact of copy number variation in the human genome. Nature 464(7289), 704-712 (2010).
    • (2010) Nature , vol.464 , Issue.7289 , pp. 704-712
    • Conrad, D.F.1    Pinto, D.2    Redon, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.