IMPDH activity in thiopurine-treated patients with inflammatory bowel disease - Relation to TPMT activity and metabolite concentrations

British Journal of Clinical Pharmacology

Volumn 65, Issue 1, 2008, Pages 69-77

  Haglund, Sofie ^a,b   Taipalensuu, Jan ^a   Peterson, Curt ^b   Almer, Sven ^b  

^a RYHOV COUNTY HOSPITAL   (Sweden)

^b LINKÖPING UNIVERSITY   (Sweden)

Author keywords

6 mercaptopurine; Azathioprine; IMPDH; Inflammatory bowel disease; Inosine 5 monophosphate dehydrogenase; Thiopurine

Indexed keywords

AZATHIOPRINE; CORTICOSTEROID; DRUG METABOLITE; INOSINATE DEHYDROGENASE; MERCAPTOPURINE; MESALAZINE; THIOPURINE METHYLTRANSFERASE;

ADULT; AGED; ARTICLE; BLOOD CELL COUNT; BLOOD DONOR; CORRELATION ANALYSIS; DISEASE ACTIVITY; DNA EXTRACTION; DRUG EFFECT; ENTERITIS; ENZYME ACTIVITY; ENZYME SYNTHESIS; ERYTHROCYTE; FEMALE; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MONONUCLEAR CELL; PRIORITY JOURNAL; REMISSION; UNSPECIFIED SIDE EFFECT;

6-MERCAPTOPURINE; ADULT; AGED; AGED, 80 AND OVER; AZATHIOPRINE; BIOLOGICAL MARKERS; FEMALE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; IMP DEHYDROGENASE; INFLAMMATORY BOWEL DISEASES; MALE; METHYLTRANSFERASES; MIDDLE AGED; POLYMORPHISM, GENETIC;

EID: 37249032702     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2007.02985.x     Document Type: Article

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