Antioxidative and anti-inflammatory protection from carnosine in the striatum of MPTP-treated mice

Journal of Agricultural and Food Chemistry

Volumn 58, Issue 21, 2010, Pages 11510-11516

  Tsai, Shih Jei ^a,b   Kuo, Wei Wen ^c   Liu, Wen Hu ^a   Yin, Mei Chin ^c,d  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

^d ASIA UNIVERSITY   (Taiwan)

Author keywords

Carnosine; iNOS activity; mRNA expression; oxidative stress; Parkinson's disease

Indexed keywords

ANTI-INFLAMMATORIES; CARNOSINE; DRINKING WATER; GLUTATHIONE CONTENTS; GLUTATHIONE PEROXIDASE; GLUTATHIONES; HOMOVANILLIC ACID; INDUCIBLE NITRIC OXIDE SYNTHASE (INOS); INFLAMMATORY CYTOKINES; INOS ACTIVITY; INTERLEUKIN-6; MALONDIALDEHYDE; MRNA EXPRESSION; NEUROPROTECTIVE EFFECTS; PARKINSON'S DISEASE; REACTIVE OXYGEN SPECIES; STRIATUM; SUPEROXIDE DISMUTASES; TUMOR NECROSIS FACTORS;

ALDEHYDES; NEURODEGENERATIVE DISEASES; NITRIC OXIDE; OXIDATIVE STRESS; OXYGEN; PARKS; PLANTS (BOTANY); POTABLE WATER;

NUCLEIC ACIDS;

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; CARNOSINE; GLUTATHIONE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; MALONALDEHYDE; NEUROPROTECTIVE AGENT; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ARTICLE; C57BL MOUSE; CORPUS STRIATUM; DRUG EFFECT; HUMAN; IMMUNOLOGY; MALE; MOUSE; PARKINSON DISEASE;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; CARNOSINE; CORPUS STRIATUM; GLUTATHIONE; HUMANS; INTERLEUKIN-6; MALE; MALONDIALDEHYDE; MICE; MICE, INBRED C57BL; NEUROPROTECTIVE AGENTS; NITRIC OXIDE SYNTHASE TYPE II; PARKINSON DISEASE; TUMOR NECROSIS FACTOR-ALPHA;

MUS;

EID: 78149342453     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf103258p     Document Type: Article

References (31)

1. Schapira, A. H. Present and future drug treatment for Parkinson's disease J. Neurol. Neurosurg. Psychiatry 2005, 76, 1472-1478
2. Fuxe, K.; Manger, P.; Genedani, S.; Agnati, L. The nigrostriatal DA pathway and Parkinson's disease J. Neural. Transm. Suppl. 2006, 70, 71-83
3. 2 and ATP production and on dopamine and DOPAC in the striatum J. Physiol. Biochem. 1999, 55, 325-331
4. Bezard, E.; Dovero, S.; Prunier, C.; Ravenscroft, P.; Chalon, S.; Guilloteau, D.; Crossman, A. R.; Bioulac, B.; Brotchie, J. M.; Gross, C. E. Relationship between the appearance of symptoms and the level of nigrostriatal degeneration in a progressive 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine- lesioned macaque model of Parkinson's disease J. Neurosci. 2001, 21, 6853-6861
5. Beal, M. F. Mitochondria, oxidative damage, and inflammation in Parkinson's disease Ann. N.Y. Acad. Sci. 2003, 991, 120-131
6. Miller, R. L.; James-Kracke, M.; Sun, G. Y.; Sun, A. Y. Oxidative and inflammatory pathways in Parkinson's disease Neurochem. Res. 2009, 34, 55-65
7. Suganuma, H.; Hirano, T.; Arimoto, Y.; Inakuma, T. Effect of tomato intake on striatal monoamine level in a mouse model of experimental Parkinson's disease J. Nutr. Sci. Vitaminol. 2002, 48, 251-254
8. Chen, C. M.; Yin, M. C.; Hsu, C. C.; Liu, T. C. Anti-oxidative and anti-inflammatory effects of four cysteine-containing agents in striatum of MPTP-treated mice Nutrition 2007, 23, 589-597
9. Bonfanti, L.; Peretto, P.; De Marchis, S.; Fasolo, A. Carnosine-related dipeptides in the mammalian brain Prog. Neurobiol. 1999, 59, 333-353
10. Maynard, L. M.; Boissonneault, G. A.; Chow, L. K.; Bruckner, G. G. High levels of dietary carnosine are associated with increased concentrations of carnosine and histidine in rat soleus muscle J. Nutr. 2001, 131, 287-290
11. Liu, W. H.; Liu, T. C.; Yin, M. C. Beneficial effects of histidine and carnosine on ethanol-induced chronic liver injury Food Chem. Toxicol. 2008, 46, 1503-1509
12. Hipkiss, A. R. Carnosine, diabetes and Alzheimer's disease Expert Rev. Neurother. 2009, 9, 583-585
13. Shen, Y.; Hu, W. W.; Fan, Y. Y.; Dai, H. B.; Fu, Q. L.; Wei, E. Q.; Luo, J. H.; Chen, Z. Carnosine protects against NMDA-induced neurotoxicity in differentiated rat PC12 cells through carnosine-histidine-histamine pathway and H(1)/H(3) receptors Biochem. Pharmacol. 2007, 73, 709-717
14. Fu, Q.; Dai, H.; Hu, W.; Fan, Y.; Shen, Y.; Zhang, W.; Chen, Z. Carnosine protects against Abeta42-induced neurotoxicity in differentiated rat PC12 cells Cell Mol. Neurobiol. 2008, 28, 307-316
15. Richardson, J. R.; Caudle, W. M.; Wang, M.; Dean, E. D.; Pennell, K. D.; Miller, G. W. Developmental exposure to the pesticide dieldrin alters the dopamine system and increases neurotoxicity in an animal model of Parkinson's disease FASEB J. 2006, 20, 1695-1697
16. Gupta, R.; Dubey, D. K.; Kannan, G. M.; Flora, S. J. S. Concomitant administration of Moringa oleifera seed powder in the remediation of arsenic-induced oxidative stress in mouse Cell Biol. Int. 2007, 31, 44-56
17. Kamal, M. A.; Jiang, H.; Hu, Y.; Keep, R. F.; Smith, D. E. Influence of genetic knockout of Pept2 on the in vivo disposition of endogenous and exogenous carnosine in wild-type and Pept2 null mice Am. J. Physiol. Regul. Integr. Comp. Physiol. 2009, 296, R986-991
18. Benzie, I. F.; Strain, J. J. The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": the FRAP assay Anal. Chem. 1996, 239, 70-76
19. Sutherland, B. A.; Shaw, O. M.; Clarkson, A. N.; Jackson, D. N.; Sammut, I. A.; Appleton, I. Neuroprotective effects of (-)-epigallocatechin gallate following hypoxia-ischemia-induced brain damage: novel mechanisms of action FASEB J. 2005, 19, 258-260
20. Xu, Z.; Cawthon, D.; McCastlain, K. A.; Slikker, W., Jr.; Ali, S. F. Selective alterations of gene expression in mice induced by MPTP Synapse 2005, 55, 45-51
21. Lee, J. W.; Miyawaki, H.; Bobst, E. V.; Hester, J. D.; Ashraf, M.; Bobst, A. M. Improved functional recovery of ischemic rat hearts due to singlet oxygen scavengers histidine and carnosine J. Mol. Cell Cardiol. 1999, 31, 113-121
22. Bharath, S.; Hsu, M.; Kaur, D.; Rajagopalan, S.; Andersen, J. K. Glutathione, iron and Parkinson's disease Biochem. Pharmacol. 2002, 64, 1037-1048
23. Nagatsu, T.; Mogi, M.; Ichinose, H.; Togari, A. Changes in cytokines and neurotrophins in Parkinson's disease J. Neural. Trans. 2000, 60, 277-290
24. Ferger, B.; Leng, A.; Mura, A.; Hengerer, B.; Feldon, J. Genetic ablation of tumor necrosis factor-alpha (TNF-alpha) and pharmacological inhibition of TNF-synthesis attenuates MPTP toxicity in mouse striatum J. Neurochem. 2004, 89, 822-833
25. Okuno, T.; Nakatsuji, Y.; Kumanogoh, A.; Moriya, M.; Ichinose, H.; Sumi, H.; Fujimura, H.; Kikutani, H.; Sakoda, S. Loss of dopaminergic neurons by the induction of inducible nitric oxide synthase and cyclooxygenase-2 via CD 40: relevance to Parkinson's disease J. Neurosci. Res. 2005, 81, 874-882
26. Knott, C.; Stern, G.; Wilkin, G. P. Inflammatory regulators in Parkinson's disease: iNOS, lipocortin-1, and cyclooxygenase-1 and -2 Mol. Cell Neurosci. 2000, 16, 724-739
27. Madrigal, J. L.; Hurtado, O.; Moro, M. A.; Lizasoain, I.; Lorenzo, P.; Castrillo, A.; Boscá, L.; Leza, J. C. The increase in TNF-alpha levels is implicated in NF-kappaB activation and inducible nitric oxide synthase expression in brain cortex after immnbilization stress Neuropsychopharmacology 2002, 26, 155-163
28. Eberhardt, W.; Beeg, T.; Beck, K. F.; Walpen, S.; Gauer, S.; Böhles, H.; Pfeilschifter, J. Nitric oxide modulates expression of matrix metalloproteinase-9 in rat mesangial cells Kidney Int. 2000, 57, 59-69
29. Miller, G. W.; Gainetdinov, R. R.; Levey, A. I.; Caron, M. G. Dopamine transporters and neuronal injury Trends Pharmacol. Sci. 1999, 20, 424-429
30. Kurosaki, R.; Muramatsu, Y.; Watanabe, H.; Michimata, M.; Matsubara, M.; Imai, Y.; Araki, T. Role of dopamine transporter against MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity in mice Metab. Brain Dis. 2003, 18, 139-146
31. Park, Y. J.; Volpe, S. L.; Decker, E. A. Quantitation of carnosine in humans plasma after dietary consumption of beef J. Agric. Food Chem. 2005, 53, 4736-4739