-
3
-
-
0032478818
-
+ conduction and selectivity
-
+ conduction and selectivity Science 280, 69-77
-
(1998)
Science
, vol.280
, pp. 69-77
-
-
Doyle, D.A.1
Morais, C.J.2
Pfuetzner, R.A.3
Kuo, A.4
Gulbis, J.M.5
Cohen, S.L.6
Chait, B.T.7
MacKinnon, R.8
-
5
-
-
2142758648
-
Ion binding affinity in the cavity of the KcsA potassium channel
-
Zhou, Y. and MacKinnon, R. (2004) Ion binding affinity in the cavity of the KcsA potassium channel Biochemistry 43, 4978-4982
-
(2004)
Biochemistry
, vol.43
, pp. 4978-4982
-
-
Zhou, Y.1
MacKinnon, R.2
-
6
-
-
0242657337
-
Potassium channels
-
MacKinnon, R. (2003) Potassium channels FEBS Lett. 555, 62-65
-
(2003)
FEBS Lett.
, vol.555
, pp. 62-65
-
-
MacKinnon, R.1
-
7
-
-
28544453561
-
Principles of selective ion transport in channels and pumps
-
Gouaux, E. and MacKinnon, R. (2005) Principles of selective ion transport in channels and pumps Science 310, 1461-1465
-
(2005)
Science
, vol.310
, pp. 1461-1465
-
-
Gouaux, E.1
MacKinnon, R.2
-
8
-
-
7244251461
-
Control of ion selectivity in potassium channels by electrostatic and dynamic properties of carbonyl ligands
-
Noskov, S. Y., Berneche, S., and Roux, B. (2004) Control of ion selectivity in potassium channels by electrostatic and dynamic properties of carbonyl ligands Nature 431, 830-834
-
(2004)
Nature
, vol.431
, pp. 830-834
-
-
Noskov, S.Y.1
Berneche, S.2
Roux, B.3
-
9
-
-
34250333069
-
+ channels is due to topological control of the permeant ion's coordinated state
-
+ channels is due to topological control of the permeant ion's coordinated state Proc. Natl. Acad. Sci. U.S.A. 104, 9260-9265
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 9260-9265
-
-
Bostick, D.L.1
Iii, L.B.C.2
-
10
-
-
35348997382
-
The predominant role of coordination number in potassium channel selectivity
-
Thomas, M., Jayatilaka, D., and Corry, B. (2007) The predominant role of coordination number in potassium channel selectivity Biophys. J. 93, 2635-2643
-
(2007)
Biophys. J.
, vol.93
, pp. 2635-2643
-
-
Thomas, M.1
Jayatilaka, D.2
Corry, B.3
-
11
-
-
34548262701
-
Tuning ion coordination architectures to enable selective partitioning
-
Varma, S. and Rempe, S. B. (2007) Tuning ion coordination architectures to enable selective partitioning Biophys. J. 93, 1093-1099
-
(2007)
Biophys. J.
, vol.93
, pp. 1093-1099
-
-
Varma, S.1
Rempe, S.B.2
-
12
-
-
38049095537
-
+ selectivity in K channels and valinomycin: Over-coordination versus cavity-size constraints
-
+ selectivity in K channels and valinomycin: over-coordination versus cavity-size constraints J. Mol. Biol. 376, 13-22
-
(2008)
J. Mol. Biol.
, vol.376
, pp. 13-22
-
-
Varma, S.1
Sabo, D.2
Rempe, S.B.3
-
13
-
-
0030752535
-
Single channel seeks permeant ion for brief but intimate relationship
-
Yellen, G. (1997) Single channel seeks permeant ion for brief but intimate relationship J. Gen. Physiol. 110, 83-85
-
(1997)
J. Gen. Physiol.
, vol.110
, pp. 83-85
-
-
Yellen, G.1
-
15
-
-
33749575060
-
Effects of conducting and blocking ions on the structure and stability of the potassium channel KcsA
-
Renart, M. L., Barrera, F. N., Molina, M. L., Encinar, J. A., Poveda, J. A., Fernandez, A. M., Gomez, J., and Gonzalez-Ros, J. M. (2006) Effects of conducting and blocking ions on the structure and stability of the potassium channel KcsA J. Biol. Chem. 281, 29905-29915
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 29905-29915
-
-
Renart, M.L.1
Barrera, F.N.2
Molina, M.L.3
Encinar, J.A.4
Poveda, J.A.5
Fernandez, A.M.6
Gomez, J.7
Gonzalez-Ros, J.M.8
-
16
-
-
1542297730
-
K channel gating by an affinity-switching selectivity filter
-
VanDongen, A. M. (2004) K channel gating by an affinity-switching selectivity filter Proc. Natl. Acad. Sci. U.S.A. 101, 3248-3252
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 3248-3252
-
-
Vandongen, A.M.1
-
18
-
-
27444441821
-
Unfolding and refolding in vitro of a tetrameric, alpha-helical membrane protein: The prokaryotic potassium channel KcsA
-
Barrera, F. N., Renart, M. L., Molina, M. L., Poveda, J. A., Encinar, J. A., Fernandez, A. M., Neira, J. L., and Gonzalez-Ros, J. M. (2005) Unfolding and refolding in vitro of a tetrameric, alpha-helical membrane protein: the prokaryotic potassium channel KcsA Biochemistry 44, 14344-14352
-
(2005)
Biochemistry
, vol.44
, pp. 14344-14352
-
-
Barrera, F.N.1
Renart, M.L.2
Molina, M.L.3
Poveda, J.A.4
Encinar, J.A.5
Fernandez, A.M.6
Neira, J.L.7
Gonzalez-Ros, J.M.8
-
20
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli, U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227, 680-685
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
21
-
-
1642483662
-
Redesigning the folding energetics of a model three-helix bundle protein by site-directed mutagenesis
-
Lopes, D. H., Chapeaurouge, A., Manderson, G. A., Johansson, J. S., and Ferreira, S. T. (2004) Redesigning the folding energetics of a model three-helix bundle protein by site-directed mutagenesis J. Biol. Chem. 279, 10991-10996
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 10991-10996
-
-
Lopes, D.H.1
Chapeaurouge, A.2
Manderson, G.A.3
Johansson, J.S.4
Ferreira, S.T.5
-
22
-
-
77953896086
-
Occupancy of nonannular lipid binding sites on KcsA greatly increases the stability of the tetrameric protein
-
in press
-
Triano, I., Barrera, F. N., Renart, M. L., Molina, M. L., Fernandez-Ballester, G., Poveda, J. A., Fernandez, A. M., Encinar, J. A., Ferrer-Montiel, A. V., Otzen, D., and Gonzalez-Ros, J. M. (2010) Occupancy of nonannular lipid binding sites on KcsA greatly increases the stability of the tetrameric protein, Biochemistry (in press).
-
(2010)
Biochemistry
-
-
Triano, I.1
Barrera, F.N.2
Renart, M.L.3
Molina, M.L.4
Fernandez-Ballester, G.5
Poveda, J.A.6
Fernandez, A.M.7
Encinar, J.A.8
Ferrer-Montiel, A.V.9
Otzen, D.10
Gonzalez-Ros, J.M.11
-
23
-
-
39649096540
-
Protein self-assembly and lipid binding in the folding of the potassium channel KcsA
-
Barrera, F. N., Renart, M. L., Poveda, J. A., de, K. B., Killian, J. A., and Gonzalez-Ros, J. M. (2008) Protein self-assembly and lipid binding in the folding of the potassium channel KcsA Biochemistry 47, 2123-2133
-
(2008)
Biochemistry
, vol.47
, pp. 2123-2133
-
-
Barrera, F.N.1
Renart, M.L.2
Poveda, J.A.3
De, K.B.4
Killian, J.A.5
Gonzalez-Ros, J.M.6
-
24
-
-
33645502287
-
Thermodynamics of unfolding of an integral membrane protein in mixed micelles
-
Sehgal, P. and Otzen, D. E. (2006) Thermodynamics of unfolding of an integral membrane protein in mixed micelles Protein Sci. 15, 890-899
-
(2006)
Protein Sci.
, vol.15
, pp. 890-899
-
-
Sehgal, P.1
Otzen, D.E.2
-
25
-
-
0008262867
-
Differential scanning microcalorimetry
-
(Harding, S. E. and Chowdhry, B. Z., Eds.), Oxford University Press, Oxford, U.K.
-
Cooper, A., Nutley, M. A., and Wadood, A. (2000) Differential scanning microcalorimetry, in Protein-Ligand Interactions: hydrodynamics and calorimetry (Harding, S. E. and Chowdhry, B. Z., Eds.) pp 287-318, Oxford University Press, Oxford, U.K.
-
(2000)
Protein-Ligand Interactions: Hydrodynamics and Calorimetry
, pp. 287-318
-
-
Cooper, A.1
Nutley, M.A.2
Wadood, A.3
Harding, S.E.4
Chowdhry, B.Z.5
-
26
-
-
0000826487
-
Biochemical applications of differential scanning calorimetry
-
Sturtevant, J. M. (1987) Biochemical applications of differential scanning calorimetry Annu. Rev. Phys. Chem. 38, 463-488
-
(1987)
Annu. Rev. Phys. Chem.
, vol.38
, pp. 463-488
-
-
Sturtevant, J.M.1
-
27
-
-
33846622066
-
Ligand effects on protein thermodynamic stability
-
Sanchez-Ruiz, J. M. (2007) Ligand effects on protein thermodynamic stability Biophys. Chem. 126, 43-49
-
(2007)
Biophys. Chem.
, vol.126
, pp. 43-49
-
-
Sanchez-Ruiz, J.M.1
-
28
-
-
0002518285
-
Optical spectroscopy to characterize protein conformation
-
(Creighton, T. E., Ed.) 2 nd ed., IRL Press, Oxford, U.K.
-
Schmid, F. X. (1997) Optical spectroscopy to characterize protein conformation, in Protein Structure: A Practical Approach (Creighton, T. E., Ed.) 2 nd ed., pp 261-298, IRL Press, Oxford, U.K.
-
(1997)
Protein Structure: A Practical Approach
, pp. 261-298
-
-
Schmid, F.X.1
Creighton, T.E.2
-
29
-
-
33745041507
-
Molecular determinants of gating at the potassium-channel selectivity filter
-
Cordero-Morales, J. F., Cuello, L. G., Zhao, Y., Jogini, V., Cortes, D. M., Roux, B., and Perozo, E. (2006) Molecular determinants of gating at the potassium-channel selectivity filter Nat. Struct. Mol. Biol. 13, 311-318
-
(2006)
Nat. Struct. Mol. Biol.
, vol.13
, pp. 311-318
-
-
Cordero-Morales, J.F.1
Cuello, L.G.2
Zhao, Y.3
Jogini, V.4
Cortes, D.M.5
Roux, B.6
Perozo, E.7
-
31
-
-
0033823118
-
The barium site in a potassium channel by x-ray crystallography
-
Jiang, Y. and MacKinnon, R. (2000) The barium site in a potassium channel by x-ray crystallography J. Gen. Physiol. 115, 269-272
-
(2000)
J. Gen. Physiol.
, vol.115
, pp. 269-272
-
-
Jiang, Y.1
MacKinnon, R.2
-
33
-
-
0142185496
-
+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates
-
+ selectivity filter: charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates J. Mol. Biol. 333, 965-975
-
(2003)
J. Mol. Biol.
, vol.333
, pp. 965-975
-
-
Zhou, Y.1
MacKinnon, R.2
-
35
-
-
17044400911
-
A gate in the selectivity filter of potassium channels
-
Berneche, S. and Roux, B. (2005) A gate in the selectivity filter of potassium channels Structure 13, 591-600
-
(2005)
Structure
, vol.13
, pp. 591-600
-
-
Berneche, S.1
Roux, B.2
-
37
-
-
33750530193
-
Detection of the opening of the bundle crossing in KcsA with fluorescence lifetime spectroscopy reveals the existence of two gates for ion conduction
-
Blunck, R., Cordero-Morales, J. F., Cuello, L. G., Perozo, E., and Bezanilla, F. (2006) Detection of the opening of the bundle crossing in KcsA with fluorescence lifetime spectroscopy reveals the existence of two gates for ion conduction J. Gen. Physiol. 128, 569-581
-
(2006)
J. Gen. Physiol.
, vol.128
, pp. 569-581
-
-
Blunck, R.1
Cordero-Morales, J.F.2
Cuello, L.G.3
Perozo, E.4
Bezanilla, F.5
-
38
-
-
71449094441
-
Mechanism of potassium-channel selectivity revealed by Na(+) and Li(+) binding sites within the KcsA pore
-
Thompson, A. N., Kim, I., Panosian, T. D., Iverson, T. M., Allen, T. W., and Nimigean, C. M. (2009) Mechanism of potassium-channel selectivity revealed by Na(+) and Li(+) binding sites within the KcsA pore Nat. Struct. Mol. Biol. 16, 1317-1324
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 1317-1324
-
-
Thompson, A.N.1
Kim, I.2
Panosian, T.D.3
Iverson, T.M.4
Allen, T.W.5
Nimigean, C.M.6
-
39
-
-
55949109148
-
Conformational changes in the selectivity filter of the open-state KcsA channel: An energy minimization study
-
Miloshevsky, G. V. and Jordan, P. C. (2008) Conformational changes in the selectivity filter of the open-state KcsA channel: an energy minimization study Biophys. J. 95, 3239-3251
-
(2008)
Biophys. J.
, vol.95
, pp. 3239-3251
-
-
Miloshevsky, G.V.1
Jordan, P.C.2
-
40
-
-
77950913923
-
Structural basis underlying the dual gate properties of KcsA
-
Imai, S., Osawa, M., Takeuchi, K., and Shimada, I. (2010) Structural basis underlying the dual gate properties of KcsA Proc. Natl. Acad. Sci. U.S.A. 107, 6216-6221
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 6216-6221
-
-
Imai, S.1
Osawa, M.2
Takeuchi, K.3
Shimada, I.4
-
41
-
-
0035996966
-
K(+) versus Na(+) ions in a K channel selectivity filter: A simulation study
-
Shrivastava, I. H., Tieleman, D. P., Biggin, P. C., and Sansom, M. S. (2002) K(+) versus Na(+) ions in a K channel selectivity filter: a simulation study Biophys. J. 83, 633-645
-
(2002)
Biophys. J.
, vol.83
, pp. 633-645
-
-
Shrivastava, I.H.1
Tieleman, D.P.2
Biggin, P.C.3
Sansom, M.S.4
-
43
-
-
9744272384
-
Influence of C-terminal protein domains and protein-lipid interactions on tetramerization and stability of the potassium channel KcsA
-
Molina, M. L., Encinar, J. A., Barrera, F. N., Fernandez-Ballester, G., Riquelme, G., and Gonzalez-Ros, J. M. (2004) Influence of C-terminal protein domains and protein-lipid interactions on tetramerization and stability of the potassium channel KcsA Biochemistry 43, 14924-14931
-
(2004)
Biochemistry
, vol.43
, pp. 14924-14931
-
-
Molina, M.L.1
Encinar, J.A.2
Barrera, F.N.3
Fernandez-Ballester, G.4
Riquelme, G.5
Gonzalez-Ros, J.M.6
-
44
-
-
0030752535
-
Single channel seeks permeant ion for brief but intimate relationship
-
Yellen, G. (1997) Single channel seeks permeant ion for brief but intimate relationship J. Gen. Physiol. 110, 83-85
-
(1997)
J. Gen. Physiol.
, vol.110
, pp. 83-85
-
-
Yellen, G.1
-
45
-
-
33644686444
-
A structural perspective on enzymes activated by monovalent cations
-
DiCera, E. (2006) A structural perspective on enzymes activated by monovalent cations J. Biol. Chem. 281, 1305-1308
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 1305-1308
-
-
Dicera, E.1
|