Occupancy of nonannular lipid binding sites on KcsA greatly increases the stability of the tetrameric protein

Biochemistry

Volumn 49, Issue 25, 2010, Pages 5397-5404

  Triano, I ^a   Barrera, F N ^a   Renart, M L ^a   Molina, M L ^a   Fernandez Ballester G ^a   Poveda, J A ^a   Fernandez A M ^a   Encinar, J A ^a   Ferrer Montiel, A V ^a   Otzen, D ^a   Gonzalez Ros J M ^a  

^a MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

A-THERMAL; ACYL CHAIN; ALKYL SULFATES; ANIONIC PHOSPHOLIPIDS; CARBON ATOMS; CONCENTRATION-DEPENDENT; DOCKING MODELS; HYDROPHOBIC POCKETS; LIPID BINDING SITES; MIXED MICELLES; PHOSPHATIDIC ACIDS; PHOSPHATIDYLGLYCEROLS; POTASSIUM CHANNELS; PROTEIN DOMAINS; PROTEIN STABILITY; PROTEIN STABILIZATION; TRANSMEMBRANE SEGMENTS; X-RAY CRYSTALLOGRAPHIC STRUCTURES;

AMPHIPHILES; BINDING ENERGY; BINDING SITES; BIOCHEMISTRY; HYDROCARBONS; MOLECULAR INTERACTIONS; PHOSPHOLIPIDS; POTASSIUM; PYROLYSIS; STABILITY;

PROTEINS;

ALKYLSULFATE; AMPHOPHILE; CARBON; DODECYL SULFATE SODIUM; DODECYLBETA DEXTRO MALTOSIDE; HYDROXYBENZOIC ACID DERIVATIVE; KCSA; LIPID; PHOSPHATIDIC ACID; PHOSPHATIDYLGLYCEROL; PHOSPHOLIPID; SULFATE; TETRAMER; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DENATURATION; HYDROPHOBICITY; MICELLE; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN STABILITY; THERMAL ANALYSIS; THERMODYNAMICS;

BACTERIAL PROTEINS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; LIPID METABOLISM; MODELS, MOLECULAR; POTASSIUM CHANNELS; PROTEIN CONFORMATION; PROTEIN DENATURATION; SPECTROMETRY, FLUORESCENCE;

PROKARYOTA;

EID: 77953896086     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi1003712     Document Type: Article

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