Synthesis and in vitro antifungal activities of new 3-substituted benzopyrone derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 23, 2010, Pages 7106-7109

  Lv, Zhiliang ^a   Sheng, Chunquan ^a   Zhang, Yikai ^a   Wang, Tiantian ^a   Feng, Jilu ^a   Sun, Hailing ^a   Zhong, Hanyu ^a   Zhang, Mingfeng ^a   Chen, Huan ^a   Li, Ke ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Antifungal activity; Benzopyrone derivative; Lanosterol 14 demethylase (CYP51); Molecular docking; Synthesis

Indexed keywords

BENZOPYRAN DERIVATIVE; FLUCONAZOLE; KETOCONAZOLE; POSACONAZOLE; VORICONAZOLE;

ANTIFUNGAL ACTIVITY; ARTICLE; DRUG DESIGN; DRUG SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR DOCKING; STRUCTURE ACTIVITY RELATION; TRICHOPHYTON RUBRUM;

14-ALPHA DEMETHYLASE INHIBITORS; ANTIFUNGAL AGENTS; BENZOPYRANS; COMPUTER SIMULATION; DRUG DESIGN; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MICROBIAL SENSITIVITY TESTS; PROTEIN BINDING; PYRONES; STEROL 14-DEMETHYLASE; STRUCTURE-ACTIVITY RELATIONSHIP; TRICHOPHYTON;

TRICHOPHYTON RUBRUM;

EID: 78149284125     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.09.072     Document Type: Article

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