A Parallel excitation based fluorescence molecular tomography system for whole-body simultaneous imaging of small animals

Annals of Biomedical Engineering

Volumn 38, Issue 11, 2010, Pages 3440-3448

  Liu, Fei ^a   Liu, Xin ^a   Wang, Daifa ^a   Zhang, Bin ^a   Bai, Jing ^a  

^a Tsinghua University   (China)

Author keywords

Fluorescence molecular tomography; Image reconstruction techniques; Medical and biological imaging

Indexed keywords

ANIMAL BODY; DATA SETS; FLUORESCENCE MARKERS; FLUORESCENCE MOLECULAR TOMOGRAPHY; FLUORESCENT TARGETS; IMAGE RECONSTRUCTION TECHNIQUES; IMAGING PROCESS; IN-VIVO; IN-VIVO IMAGING; MEDICAL AND BIOLOGICAL IMAGING; NON-CONTACT; NUDE MICE; ORDERS OF MAGNITUDE; PARALLEL EXCITATION; PHYSIOLOGICAL PROCESS; SIMULTANEOUS IMAGING; SINGLE POINT; SMALL ANIMAL; SPATIAL SAMPLING; WHOLE-BODY;

ANIMALS; FLUORESCENCE; IMAGE RECONSTRUCTION; PERMITTIVITY; PHYSIOLOGY; TOMOGRAPHY;

MEDICAL IMAGING;

ANIMAL; ARTICLE; COMPUTER ASSISTED EMISSION TOMOGRAPHY; FLUORESCENCE; IMAGE PROCESSING; INSTRUMENTATION; METHODOLOGY; MOUSE;

ANIMALS; FLUORESCENCE; IMAGE PROCESSING, COMPUTER-ASSISTED; MICE; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 78149282081     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-010-0093-4     Document Type: Article

References (36)

1. EI Altinoǧlu TJ Russin JM Kaiser BM Barth PC Eklund M Kester JH Adair 2008 Near-infrared emitting fluorophore-doped calcium phosphate nanoparticles for in vivo imaging of human breast cancer ACS Nano. 2 10 2075 2084 10.1021/nn800448r 19206454
2. NC Deliolanis J Dunham T Wurdinger JL Figueiredo T Bakhos V Ntziachristos 2009 In vivo imaging of murine tumors using complete-angle projection fluorescence molecular tomography J. Biomed. Opt. 14 3 030509 10.1117/1.3149854 19566290
3. N Deliolanis T Lasser D Hyde A Soubret J Ripoll V Ntziachristos 2007 Free-space fluorescence molecular tomography utilizing 360 degrees geometry projections Opt. Lett. 32 4 382 384 10.1364/OL.32.000382 17356660
4. N Deliolanis T Lasser M Niedre A Soubret V Ntziachristos 2006 In vivo lung cancer imaging in mice using 360 degrees free-space fluorescence molecular tomography Conf. Proc. IEEE Eng. Med. Biol. Soc. 1 2370 2372 10.1109/IEMBS.2006.260683 17946109
5. A Garofalakis G Zacharakis H Meyer EN Economou C Mamalaki J Papamatheakis D Kioussis V Ntziachristos J Ripoll 2007 Three-dimensional in vivo imaging of green fluorescent protein-expressing T cells in mice with noncontact fluorescence molecular tomography Mol. Imaging 6 2 96 107 17445504
6. K Gotoh T Yamada O Ishikawa H Takahashi H Eguchi M Yano H Ohigashi Y Tomita Y Miyamoto S Imaoka 2009 A novel image-guided surgery of hepatocellular carcinoma by indocyanine green fluorescence imaging navigation J. Surg. Oncol. 100 1 75 79 10.1002/jso.21272 19301311
7. EE Graves J Ripoll R Weissleder V Ntziachristos 2003 A submillimeter resolution fluorescence molecular imaging system for small animal imaging Med. Phys. 30 5 901 911 1:CAS:528:DC%2BD3sXjtl2ksLo%3D 10.1118/1.1568977 12772999
8. EE Graves R Weissleder V Ntziachristos 2004 Fluorescence molecular imaging of small animal tumor models Curr. Mol. Med. 4 4 419 430 1:CAS:528:DC%2BD2cXksFGjt7o%3D 10.2174/1566524043360555 15354872
9. J Haller D Hyde N Deliolanis R de Kleine M Niedre V Ntziachristos 2008 Visualization of pulmonary inflammation using noninvasive fluorescence molecular imaging J. Appl. Physiol. 104 3 795 802 1:CAS:528:DC%2BD1cXkt1OhtLc%3D 10.1152/japplphysiol.00959.2007 18202169
10. G Hu JJ Yao J Bai 2008 Full-angle optical imaging of near-infrared fluorescent probes implanted in small animals Prog. Nat. Sci. 18 6 707 711 10.1016/j.pnsc.2007.11.021
11. D Hyde R de Kleine SA MacLaurin E Miller DH Brooks T Krucker V Ntziachristos 2009 Hybrid FMT-CT imaging of amyloid-beta plaques in a murine Alzheimer's disease model Neuroimage 44 4 1304 1311 10.1016/j.neuroimage.2008. 10.038 19041402
12. D Hyde EL Miller DH Brooks V Ntziachristos 2010 Data specific spatially varying regularization for multimodal fluorescence molecular tomography IEEE Trans. Med. Imaging 29 2 365 374 10.1109/TMI.2009.2031112 19758858
13. A Joshi W Bangerth EM Sevick-Muraca 2004 Adaptive finite element based tomography for fluorescence optical imaging in tissue Opt. Express 12 22 5402 5417 10.1364/OPEX.12.005402 19484100
14. T Kitai T Inomoto M Miwa T Shikayama 2005 Fluorescence navigation with indocyanine green for detecting sentinel lymph nodes in breast cancer Breast Cancer 12 3 211 215 10.2325/jbcs.12.211 16110291
15. X Liu D Wang F Liu J Bai 2010 Principal component analysis of dynamic fluorescence diffuse optical tomography images Opt. Express 18 6 6300 6314 1:CAS:528:DC%2BC3cXjvFehsb0%3D 10.1364/OE.18.006300 20389653
16. G Luker K Luker 2008 Optical imaging: current applications and future directions J. Nucl. Med. 49 1 1 4 10.2967/jnumed.107.045799 18077528
17. H Meyer A Garofalakis G Zacharakis S Psycharakis C Mamalaki D Kioussis EN Economou V Ntziachristos J Ripoll 2007 Noncontact optical imaging in mice with full angular coverage and automatic surface extraction Appl. Opt. 46 17 3617 3627 10.1364/AO.46.003617 17514324
18. I Miyashiro N Miyoshi M Hiratsuka K Kishi T Yamada M Ohue H Ohigashi M Yano O Ishikawa S Imaoka 2008 Detection of sentinel node in gastric cancer surgery by indocyanine green fluorescence imaging: comparison with infrared imaging Ann. Surg. Oncol. 15 6 1640 1643 10.1245/s10434-008-9872-7 18379850
19. X Montet JL Figueiredo H Alencar V Ntziachristos U Mahmood R Weissleder 2007 Tomographic fluorescence imaging of tumor vascular volume in mice Radiology 242 3 751 758 10.1148/radiol.2423052065 17325064
20. X Montet V Ntziachristos J Grimm R Weissleder 2005 Tomographic fluorescence mapping of tumor targets Cancer Res. 65 14 6330 6336 1:CAS:528:DC%2BD2MXmt1egsbc%3D 10.1158/0008-5472.CAN-05-0382 16024635
21. V Ntziachristos 2006 Fluorescence molecular imaging Annu. Rev. Biomed. Eng. 8 1 33 1:CAS:528:DC%2BD28Xpt1Clt7k%3D 10.1146/annurev.bioeng.8.061505. 095831 16834550
22. V Ntziachristos J Ripoll LV Wang R Weissleder 2005 Looking and listening to light: the evolution of whole-body photonic imaging Nat. Biotechnol. 23 3 313 320 1:CAS:528:DC%2BD2MXitF2nt7k%3D 10.1038/nbt1074 15765087
23. V Ntziachristos EA Schellenberger J Ripoll D Yessayan E Graves A Bogdanov L Josephson R Weissleder 2004 Visualization of antitumor treatment by means of fluorescence molecular tomography with an annexin V-Cy5.5 conjugate Proc. Natl Acad. Sci. USA 101 33 12294 12299 1:CAS:528:DC%2BD2cXntFekt7Y%3D 10.1073/pnas.0401137101 15304657
24. V Ntziachristos CH Tung C Bremer R Weissleder 2002 Fluorescence molecular tomography resolves protease activity in vivo Nat. Med. 8 7 757 760 1:CAS:528:DC%2BD38XkvFeht7w%3D 10.1038/nm729 12091907
25. V Ntziachristos R Weissleder 2002 Charge-coupled-device based scanner for tomography of fluorescent near-infrared probes in turbid media Med. Phys. 29 5 803 809 10.1118/1.1470209 12033576
26. MA O'Leary DA Boas XD Li B Chance AG Yodh 1996 Fluorescence lifetime imaging in turbid media Opt. Lett. 21 2 158 160 10.1364/OL.21.000158 19865337
27. S Patwardhan S Bloch S Achilefu J Culver 2005 Time-dependent whole-body fluorescence tomography of probe bio-distributions in mice Opt. Express 13 7 2564 2577 1:CAS:528:DC%2BD2MXjvVGgsrs%3D 10.1364/OPEX.13.002564 19495147
28. M Rudin R Weissleder 2003 Molecular imaging in drug discovery and development Nat. Rev. Drug Discov. 2 2 123 131 1:CAS:528:DC%2BD3sXot12muw%3D%3D 10.1038/nrd1007 12563303
29. RB Schulz A Ale A Sarantopoulos M Freyer E Soehngen M Zientkowska V Ntziachristos 2010 Hybrid system for simultaneous fluorescence and x-ray computed tomography IEEE Trans. Med. Imaging 29 2 465 473 10.1109/TMI.2009. 2035310 19906585
30. M Schweiger SR Arridge M Hiraoka DT Delpy 1995 The finite element method for the propagation of light in scattering media: boundary and source conditions Med. Phys. 22 11 1779 1792 1:STN:280:DyaK287lvFyltg%3D%3D 10.1118/1.597634 8587533
31. X Song D Wang N Chen J Bai H Wang 2007 Reconstruction for free-space fluorescence tomography using a novel hybrid adaptive finite element algorithm Opt. Express 15 26 18300 18317 10.1364/OE.15.018300 19551128
32. A Soubret J Ripoll V Ntziachristos 2005 Accuracy of fluorescent tomography in the presence of heterogeneities: study of the normalized Born ratio IEEE Trans. Med. Imaging 24 10 1377 1386 10.1109/TMI.2005.857213 16229423
33. DF Wang X Liu J Bai 2009 Analysis of fast full angle fluorescence diffuse optical tomography with beam-forming illumination Opt. Express 17 24 21376 21395 1:CAS:528:DC%2BD1MXhsVyks7nM 10.1364/OE.17.021376 19997378
34. DF Wang X Liu Y Chen J Bai 2010 In vivo fluorescence molecular tomography based on optimal small animal surface reconstruction Chin. Opt. Lett. 8 1 82 85 10.3788/COL20100801.0082
35. KP Withrow JP Gleysteen A Safavy J Skipper RA Desmond K Zinn EL Rosenthal 2007 Assessment of indocyanine green-labeled cetuximab to detect xenografted head and neck cancer cell lines Otolaryngol. Head Neck Surg. 137 5 729 734 10.1016/j.otohns.2007.06.736 17967636
36. Zhang, H., H. Li, G. Hu, G. S. Hu, and J. Bai. Micro-CT in a dual-modality fluorescence/computed tomography system for small animal imaging. IEEE Nucl. Sci. Symp. Conf. Rec. 3735-3737, 2007.