Subtypes and variants of Mycoplasma pneumoniae: Local and temporal changes in Germany 2003-2006 and absence of a correlation between the genotype in the respiratory tract and the occurrence of genotype-specific antibodies in the sera of infected patients

Epidemiology and Infection

Volumn 138, Issue 12, 2010, Pages 1829-1837

  Dumke, R ^a   Von Baum, H ^b   Luck P C ^a   Jacobs, E ^a  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b UNIVERSITY HOSPITAL ULM   (Germany)

Author keywords

Community acquired pneumonia; Genotype distribution; Host response; Mycoplasma pneumoniae

Indexed keywords

ADHESIN; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; PROTEIN P1; UNCLASSIFIED DRUG; BACTERIAL DNA; BACTERIUM ANTIBODY; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G;

ADULT; ARTICLE; BACTERIAL STRAIN; BACTERIUM DETECTION; BACTERIUM ISOLATE; COMMUNITY ACQUIRED PNEUMONIA; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENOTYPE; GERMANY; HUMAN; MYCOPLASMA PNEUMONIAE; NONHUMAN; OUTPATIENT; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATORY SYSTEM; BACTERIUM IDENTIFICATION; BLOOD; CHEMISTRY; CLASSIFICATION; COMMUNICABLE DISEASE; DNA SEQUENCE; GENETICS; IMMUNOLOGY; ISOLATION AND PURIFICATION; MICROBIOLOGY; MYCOPLASMA PNEUMONIA; POLYMERASE CHAIN REACTION; SEROTYPING;

ADULT; ANTIBODIES, BACTERIAL; BACTERIAL TYPING TECHNIQUES; COMMUNITY-ACQUIRED INFECTIONS; DNA, BACTERIAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENOTYPE; GERMANY; HUMANS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; MYCOPLASMA PNEUMONIAE; PNEUMONIA, MYCOPLASMA; POLYMERASE CHAIN REACTION; RESPIRATORY SYSTEM; SEQUENCE ANALYSIS, DNA; SEROTYPING;

EID: 78149247808     PISSN: 09502688     EISSN: 14694409     Source Type: Journal    
DOI: 10.1017/S0950268810000622     Document Type: Article

References (41)

1. Fernald GW, Collier AM, Clyde Jr. WA. Respiratory infections due to Mycoplasma pneumoniae in infants and children. Pediatrics 1975; 55: 327-335.
2. Clyde Jr. WA. Mycoplasma pneumoniae infections of man. In: Tully JG, Whitcomb RF, eds. The Mycoplasmas. Human and Animal Mycoplasmas, vol. II. New York: Academic Press, 1979, pp. 275-306.
3. Blasi F. Atypical pathogens and respiratory tract infections. European Respiratory Journal 2004; 24: 171-181. (Pubitemid 39029084)
4. Gaillat J, et al. Community epidemiology of Chlamydia and Mycoplasma pneumoniae in LRTI in France over 29 month. European Journal of Epidemiology 2005; 20: 643-651. (Pubitemid 41126040)
5. Howard LSGE, et al. Microbiological profile of community-acquired pneumonia in adults over the last 20 years. Journal of Infection 2005; 50: 107-113.
6. Marrie TJ, et al. Etiology of community-acquired pneumonia treated in an ambulatory setting. Respiratory Medicine 2005; 99: 60-65. (Pubitemid 40017385)
7. Miyashita N, et al. Community-acquired pneumonia in Japan: a prospective ambulatory and hospitalized patient study. Journal of Medical Microbiology 2005; 54: 395-400. (Pubitemid 40489548)
8. Gutierrez F, et al. The influence of age and gender on the population-based incidence of community-acquired pneumonia caused by different microbial pathogens. Journal of Infection 2006; 53: 166-174. (Pubitemid 44227814)
9. Huang HH, et al. Community-acquired pneumonia in Shanghai, China: microbial etiology and implications for empirical therapy in a prospective study of 389 patients. European Journal of Clinical Microbiology and Infectious Diseases 2006; 25: 369-374.
10. Smith CB, Friedewald WT, Chanock RM. Shedding of Mycoplasma pneumoniae after tetracycline and erythromycin therapy. New England Journal of Medicine 1967; 276: 1172-1175.
11. Tsiodras S, et al. Central nervous system manifestations of Mycoplasma pneumoniae infections. Journal of Infection 2005; 51: 343-354. (Pubitemid 43008958)
12. Lind K, et al. A seroepidemiological study of Mycoplasma pneumoniae infections in Denmark over the 50-year period 1946-1995. European Journal of Epidemiology 1997; 13: 581-586. (Pubitemid 27306179)
13. Eun BW, et al. Mycoplasma pneumoniae in Korean children: the epidemiology of pneumonia over an 18-year period. Journal of Infection 2008; 56: 326-331.
14. Waites KB, Talkington DF. Mycoplasma pneumoniae and its role as a human pathogen. Clinical Microbiology Reviews 2004; 17: 697-728. (Pubitemid 39372513)
15. Daxboeck F, Krause R, Wenisch C. Laboratory diagnosis of Mycoplasma pneumoniae infection. Clinical Microbiology and Infection 2003; 9: 263-273. (Pubitemid 36546384)
16. Loens K, Ursi D, Goossens H, Ieven M. Molecular diagnosis of Mycoplasma pneumoniae respiratory tract infections. Journal of Clinical Microbiology 2003; 41: 4915-4923. (Pubitemid 37429897)
17. Jacobs E, et al. Are outbreaks and sporadic respiratory infections by Mycoplasma pneumoniae due to two distinct subtypes? European Journal of Clinical Microbiology and Infectious Diseases 1996; 15: 38-44. (Pubitemid 26051260)
18. Kenri T, et al. Genotyping analysis of Mycoplasma pneumoniae clinical strains in Japan between 1995 and 2005: type shift phenomenon of M. pneumoniae clinical strains. Journal of Medical Microbiology 2008; 57: 469-475. (Pubitemid 351537022)
19. Dumke R, et al. Subtyping of Mycoplasma pneumoniae isolates based on extended genome sequencing and on expression profiles. International Journal of Medical Microbiology 2003; 292: 513-525. (Pubitemid 36258462)
20. Pereyre S, et al. First report of macrolide-resistant strains and description of a novel nucleotide sequence variation in the P1 adhesin gene in Mycoplasma pneumoniae clinical strains isolated in France over 12 years. Journal of Clinical Microbiology 2007; 45: 3534-3539. (Pubitemid 350156844)
21. Schwartz SB, et al. Genotyping of Mycoplasma pneumoniae isolates using real-time PCR and highresolution melt analysis. Clinical Microbiology and Infection 2009; 15: 756-762.
22. Dumke R, et al. Culture-independent molecular subtyping of Mycoplasma pneumoniae in clinical samples. Journal of Clinical Microbiology 2006; 44: 2567-2570. (Pubitemid 44092428)
23. Dumke R, Schurwanz N, Jacobs E. Characterisation of subtype- and variant-specific antigen regions of the P1 adhesin of Mycoplasma pneumoniae. International Journal of Medical Microbiology 2008; 298: 483-491. (Pubitemid 351734785)
24. Welte T, Suttorp N, Marre R. CAPNETZ - community-acquired pneumonia competence network. Infection 2004; 32: 234-238. (Pubitemid 39070604)
25. von Baum H, et al. Community-acquired Legionella pneumonia: new insights from the German competence network for community acquired pneumonia. Clinical Infectious Diseases 2008; 46: 1356-1364. (Pubitemid 351589933)
26. Dumke R, et al. Sensitive detection of Mycoplasma pneumoniae in human respiratory tract samples by optimized real-time PCR approach. Journal of Clinical Microbiology 2007; 45: 2726-2730. (Pubitemid 47295516)
27. Schurwanz N, Jacobs E, Dumke R. A strategy to create chimeric proteins derived from functional adhesin regions of Mycoplasma pneumoniae for vaccine development. Infection and Immunity 2009; 77: 5007-5015.
28. Dégrange S, et al. Development of multiple-locus variable-number tandem-repeat analysis for molecular typing of Mycoplasma pneumoniae. Journal of Clinical Microbiology 2009; 47: 914-923.
29. Ruland K, Wenzel R, Herrmann R. Analysis of three different repeated DNA elements present in the P1 operon of Mycoplasma pneumoniae: size, number and distribution on the genome. Nucleic Acid Research 1990; 18: 6311-6317. (Pubitemid 20379180)
30. Himmelreich R, et al. Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae. Nucleic Acid Research 1996; 24: 4420-4449. (Pubitemid 26388629)
31. Su CJ, et al. Sequence divergency of the cytadhesin gene of Mycoplasma pneumoniae. Infection and Immunity 1990; 58: 2669-2674. (Pubitemid 20228255)
32. Kenri T, et al. Identification of a new variable sequence in the P1 cytadhesin gene of Mycoplasma pneumoniae: evidence for the generation of antigenic variation by DNA recombination between repetitive sequences. Infection and Immunity 1999; 67: 4557-4562. (Pubitemid 29400433)
33. Dorigo-Zetsma JW, et al. Mycoplasma pneumoniae P1 type 1- and type 2-specific sequences within the P1 cytadhesin gene of individual strains. Infection and Immunity 2001; 69: 5612-5618.
34. Dumke R, et al. Preference, adaptation and survival of Mycoplasma pneumoniae subtypes in an animal model. International Journal of Medical Microbiology 2004; 294: 149-155.
35. Hu PC, et al. Demonstration of antibodies to Mycoplasma pneumoniae attachment protein in human sera and respiratory secretions. Infection and Immunity 1983; 41: 437-439.
36. Thacker WL, Talkington DF. Analysis of complement fixation and commercial enzyme immunoassays for detection of antibodies to Mycoplasma pneumoniae in human serum. Clinical and Diagnostic Laboratory Immunology 2000; 7: 778-780.
37. Csango PA, Pederson JE, Hess RD. Comparison of four Mycoplasma pneumoniae IgM, IgG- and IgA-specific enzyme immunoassays in blood donors and patients. Clinical Microbiology and Infection 2004; 10: 1094-1098.
38. Hammerschlag MR. Mycoplasma pneumoniae infections. Current Opinion in Infectious Diseases 2001; 14: 181-186.
39. Svenstrup HF, et al. Adhesion and inhibition assay of Mycoplasma genitalium and M. pneumoniae by immunofluorescence microscopy. Journal of Medical Microbiology 2002; 51: 361-373.
40. Chaudhry R, et al. Expression and immunological characterization of the carboxy-terminal region of the P1 adhesin protein of Mycoplasma pneumoniae. Journal of Clinical Microbiology 2005; 43: 321-325. (Pubitemid 40096318)
41. Nilsson AC, Björkman P, Persson K. Polymerase chain reaction is superior to serology for the diagnosis of acute Mycoplasma pneumoniae infection and reveals a high rate of persistent infection. BMC Microbiology 2008; 8: 93-100. (Pubitemid 351952126)