메뉴 건너뛰기




Volumn 16, Issue 39, 2010, Pages 4986-4991

Up-regulation of PIK3CA promotes metastasis in gastric carcinoma

Author keywords

Akt; Gastric cancer; Metastasis; Phosphatidylinositol 3 kinase Akt pathway; PIK3CA

Indexed keywords

MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

EID: 78049499656     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v16.i39.4986     Document Type: Article
Times cited : (56)

References (26)
  • 2
    • 23944437140 scopus 로고    scopus 로고
    • Frequent loss of membranous E-cadherin in gastric cancers: A cross-talk with Wnt in determining the fate of beta-catenin
    • Cheng XX, Wang ZC, Chen XY, Sun Y, Kong QY, Liu J, Gao X, Guan HW, Li H. Frequent loss of membranous E-cadherin in gastric cancers: A cross-talk with Wnt in determining the fate of beta-catenin. Clin Exp Metastasis 2005; 22: 85-93
    • (2005) Clin Exp Metastasis , vol.22 , pp. 85-93
    • Cheng, X.X.1    Wang, Z.C.2    Chen, X.Y.3    Sun, Y.4    Kong, Q.Y.5    Liu, J.6    Gao, X.7    Guan, H.W.8    Li, H.9
  • 3
    • 33745298519 scopus 로고    scopus 로고
    • Nuclear factor-kappaB in cancer development and progression
    • Karin M. Nuclear factor-kappaB in cancer development and progression. Nature 2006; 441: 431-436
    • (2006) Nature , vol.441 , pp. 431-436
    • Karin, M.1
  • 4
    • 0028601306 scopus 로고
    • Molecular cloning, cDNA sequence, and chromosomal localization of the human phosphatidylinositol 3-kinase p110 alpha (PIK3CA) gene
    • Volinia S, Hiles I, Ormondroyd E, Nizetic D, Antonacci R, Rocchi M, Waterfield MD. Molecular cloning, cDNA sequence, and chromosomal localization of the human phosphatidylinositol 3-kinase p110 alpha (PIK3CA) gene. Genomics 1994; 24: 472-477
    • (1994) Genomics , vol.24 , pp. 472-477
    • Volinia, S.1    Hiles, I.2    Ormondroyd, E.3    Nizetic, D.4    Antonacci, R.5    Rocchi, M.6    Waterfield, M.D.7
  • 7
    • 65549088020 scopus 로고    scopus 로고
    • Frequent mutations and amplifications of the PIK3CA gene in pituitary tumors
    • Lin Y, Jiang X, Shen Y, Li M, Ma H, Xing M, Lu Y. Frequent mutations and amplifications of the PIK3CA gene in pituitary tumors. Endocr Relat Cancer 2009; 16: 301-310
    • (2009) Endocr Relat Cancer , vol.16 , pp. 301-310
    • Lin, Y.1    Jiang, X.2    Shen, Y.3    Li, M.4    Ma, H.5    Xing, M.6    Lu, Y.7
  • 8
    • 13944284494 scopus 로고    scopus 로고
    • Oncogenic mutations of PIK3CA in human cancers
    • Samuels Y, Velculescu VE. Oncogenic mutations of PIK3CA in human cancers. Cell Cycle 2004; 3: 1221-1224
    • (2004) Cell Cycle , vol.3 , pp. 1221-1224
    • Samuels, Y.1    Velculescu, V.E.2
  • 10
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-Kinase AKT pathway in human cancer
    • Vivanco I, Sawyers CL. The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat Rev Cancer 2002; 2: 489-501
    • (2002) Nat Rev Cancer , vol.2 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 14
    • 31944444234 scopus 로고    scopus 로고
    • Cancer-specific mutations in PIK3CA are oncogenic in vivo
    • Bader AG, Kang S, Vogt PK. Cancer-specific mutations in PIK3CA are oncogenic in vivo. Proc Natl Acad Sci USA 2006; 103: 1475-1479
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 1475-1479
    • Bader, A.G.1    Kang, S.2    Vogt, P.K.3
  • 15
    • 78049503985 scopus 로고    scopus 로고
    • Correlation of the expression of PIK3CA gene with the differetiation and invasiveness of gastric cancer cells
    • Liu JF, Li W, Qi YC. Correlation of the expression of PIK3CA gene with the differetiation and invasiveness of gastric cancer cells. Shiyong Zhongliuxue Zazhi 2010; 24: 127-129
    • (2010) Shiyong Zhongliuxue Zazhi , vol.24 , pp. 127-129
    • Liu, J.F.1    Li, W.2    Qi, Y.C.3
  • 16
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001; 25: 402-408
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 17
    • 3242674366 scopus 로고    scopus 로고
    • Cyclooxygenase-2 and inducible nitric oxide synthase expression in human astrocytic gliomas: Correlation with angiogenesis and prognostic significance
    • Hara A, Okayasu I. Cyclooxygenase-2 and inducible nitric oxide synthase expression in human astrocytic gliomas: correlation with angiogenesis and prognostic significance. Acta Neuropathol 2004; 108: 43-48
    • (2004) Acta Neuropathol , vol.108 , pp. 43-48
    • Hara, A.1    Okayasu, I.2
  • 19
    • 0036841057 scopus 로고    scopus 로고
    • Genomic gain of PIK3CA and increased expression of p110alpha are associated with progression of dysplasia into invasive squamous cell carcinoma
    • Woenckhaus J, Steger K, Werner E, Fenic I, Gamerdinger U, Dreyer T, Stahl U. Genomic gain of PIK3CA and increased expression of p110alpha are associated with progression of dysplasia into invasive squamous cell carcinoma. J Pathol 2002; 198: 335-342
    • (2002) J Pathol , vol.198 , pp. 335-342
    • Woenckhaus, J.1    Steger, K.2    Werner, E.3    Fenic, I.4    Gamerdinger, U.5    Dreyer, T.6    Stahl, U.7
  • 21
    • 60849109531 scopus 로고    scopus 로고
    • Genetic variations in the PI3K/PTEN/AKT/mTOR pathway are associated with clinical outcomes in esophageal cancer patients treated with chemoradiotherapy
    • Hildebrandt MA, Yang H, Hung MC, Izzo JG, Huang M, Lin J, Ajani JA, Wu X. Genetic variations in the PI3K/PTEN/AKT/mTOR pathway are associated with clinical outcomes in esophageal cancer patients treated with chemoradiotherapy. J Clin Oncol 2009; 27: 857-871
    • (2009) J Clin Oncol , vol.27 , pp. 857-871
    • Hildebrandt, M.A.1    Yang, H.2    Hung, M.C.3    Izzo, J.G.4    Huang, M.5    Lin, J.6    Ajani, J.A.7    Wu, X.8
  • 22
    • 0033604585 scopus 로고    scopus 로고
    • The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB
    • Kandel ES, Hay N. The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB. Exp Cell Res 1999; 253: 210-229
    • (1999) Exp Cell Res , vol.253 , pp. 210-229
    • Kandel, E.S.1    Hay, N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.