-
1
-
-
0141609865
-
Heparin-induced thrombocytopenia
-
Chong B.H. Heparin-induced thrombocytopenia. J Thromb Haemost 2003, 1:1471-1478.
-
(2003)
J Thromb Haemost
, vol.1
, pp. 1471-1478
-
-
Chong, B.H.1
-
2
-
-
0032958624
-
Antigens involved in heparin-induced thrombocytopenia
-
Amiral J. Antigens involved in heparin-induced thrombocytopenia. Semin Hematol 1999, 36:7-11.
-
(1999)
Semin Hematol
, vol.36
, pp. 7-11
-
-
Amiral, J.1
-
3
-
-
0032728857
-
Further characterization of antibody and antigen in heparin-induced thrombocytopenia
-
Newman P.M., Chong B.H. Further characterization of antibody and antigen in heparin-induced thrombocytopenia. Br J Haematol 1999, 107:303-309.
-
(1999)
Br J Haematol
, vol.107
, pp. 303-309
-
-
Newman, P.M.1
Chong, B.H.2
-
4
-
-
0034079490
-
Affinity purification of heparin-dependent antibodies to platelet factor 4 developed in heparin-induced thrombocytopenia: biological characteristics and effects on platelet activation
-
Amiral J., Pouplard C., Vissac A.M., et al. Affinity purification of heparin-dependent antibodies to platelet factor 4 developed in heparin-induced thrombocytopenia: biological characteristics and effects on platelet activation. Br J Haematol 2000, 109:336-341.
-
(2000)
Br J Haematol
, vol.109
, pp. 336-341
-
-
Amiral, J.1
Pouplard, C.2
Vissac, A.M.3
-
5
-
-
0034081558
-
Investigation of a platelet factor 4 polymorphism on the immune response in patients with heparin-induced thrombocytopenia
-
Horsewood P., Kelton J.G. Investigation of a platelet factor 4 polymorphism on the immune response in patients with heparin-induced thrombocytopenia. Platelets 2000, 11:23-27.
-
(2000)
Platelets
, vol.11
, pp. 23-27
-
-
Horsewood, P.1
Kelton, J.G.2
-
6
-
-
0032747473
-
Functional heterogeneity of antiheparin-platelet factor 4 antibodies: implications in the pathogenesis of the HIT syndrome
-
Ahmad S., Walenga J.M., Jeske W.P., et al. Functional heterogeneity of antiheparin-platelet factor 4 antibodies: implications in the pathogenesis of the HIT syndrome. Clin Appl Thromb Hemost 1999, 5(Suppl 1):S32-S37.
-
(1999)
Clin Appl Thromb Hemost
, vol.5
, Issue.SUPPL 1
-
-
Ahmad, S.1
Walenga, J.M.2
Jeske, W.P.3
-
7
-
-
0032211182
-
Defining an antigenic epitope on platelet factor 4 associated with heparin-induced thrombocytopenia
-
Ziporen L., Li Z.Q., Park K.S., et al. Defining an antigenic epitope on platelet factor 4 associated with heparin-induced thrombocytopenia. Blood 1998, 92:3250-3259.
-
(1998)
Blood
, vol.92
, pp. 3250-3259
-
-
Ziporen, L.1
Li, Z.Q.2
Park, K.S.3
-
8
-
-
0029819851
-
The epitope specificity of heparin-induced thrombocytopenia
-
Horsewood P., Warkentin T.E., Hayward C.P., et al. The epitope specificity of heparin-induced thrombocytopenia. Br J Haematol 1996, 95:161-167.
-
(1996)
Br J Haematol
, vol.95
, pp. 161-167
-
-
Horsewood, P.1
Warkentin, T.E.2
Hayward, C.P.3
-
9
-
-
0030703541
-
Differences in specificity of heparin-dependent antibodies developed in heparin-induced thrombocytopenia and consequences on cross-reactivity with danaparoid sodium
-
Pouplard C., Amiral J., Borg J.Y., et al. Differences in specificity of heparin-dependent antibodies developed in heparin-induced thrombocytopenia and consequences on cross-reactivity with danaparoid sodium. Br J Haematol 1997, 99:273-280.
-
(1997)
Br J Haematol
, vol.99
, pp. 273-280
-
-
Pouplard, C.1
Amiral, J.2
Borg, J.Y.3
-
10
-
-
0030136628
-
Platelet binding of IgG from patients with heparin-induced thrombocytopenia
-
[see comments]
-
Horne M.K., Alkins B.R. Platelet binding of IgG from patients with heparin-induced thrombocytopenia. J Lab Clin Med 1996, 127:435-442. [see comments].
-
(1996)
J Lab Clin Med
, vol.127
, pp. 435-442
-
-
Horne, M.K.1
Alkins, B.R.2
-
11
-
-
35448956532
-
No difference in risk for thrombocytopenia during treatment of pulmonary embolism and deep venous thrombosis with either low-molecular-weight heparin or unfractionated heparin: a meta-analysis
-
Morris T.A., Castrejon S., Devendra G., et al. No difference in risk for thrombocytopenia during treatment of pulmonary embolism and deep venous thrombosis with either low-molecular-weight heparin or unfractionated heparin: a meta-analysis. Chest 2007, 132:1131-1139.
-
(2007)
Chest
, vol.132
, pp. 1131-1139
-
-
Morris, T.A.1
Castrejon, S.2
Devendra, G.3
-
12
-
-
0033029056
-
Failure of early heparin cessation as treatment for heparin-induced thrombocytopenia
-
Wallis D.E., Workman D.L., Lewis B.E., et al. Failure of early heparin cessation as treatment for heparin-induced thrombocytopenia. Am J Med 1999, 106:629-635.
-
(1999)
Am J Med
, vol.106
, pp. 629-635
-
-
Wallis, D.E.1
Workman, D.L.2
Lewis, B.E.3
-
13
-
-
45949103154
-
Treatment and prevention of heparin-induced thrombocytopenia: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th edition)
-
Warkentin T.E., Greinacher A., Koster A., et al. Treatment and prevention of heparin-induced thrombocytopenia: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th edition). Chest 2008, 133:340S-380S.
-
(2008)
Chest
, vol.133
-
-
Warkentin, T.E.1
Greinacher, A.2
Koster, A.3
-
14
-
-
0038285887
-
Argatroban anticoagulation in patients with heparin-induced thrombocytopenia
-
Lewis B.E., Wallis D.E., Leya F., et al. Argatroban anticoagulation in patients with heparin-induced thrombocytopenia. Arch Intern Med 2003, 163:1849-1856.
-
(2003)
Arch Intern Med
, vol.163
, pp. 1849-1856
-
-
Lewis, B.E.1
Wallis, D.E.2
Leya, F.3
-
16
-
-
0025204512
-
Pharmacology of low molecular weight heparins
-
Harenberg J. Pharmacology of low molecular weight heparins. Semin Thromb Hemost 1990, 16(Suppl):12-18.
-
(1990)
Semin Thromb Hemost
, vol.16
, Issue.SUPPL
, pp. 12-18
-
-
Harenberg, J.1
-
17
-
-
0026690347
-
Role of the antithrombin-binding pentasaccharide in heparin acceleration of antithrombin-proteinase reactions. Resolution of the antithrombin conformational change contribution to heparin rate enhancement
-
Olson S.T., Bjork I., Sheffer R., et al. Role of the antithrombin-binding pentasaccharide in heparin acceleration of antithrombin-proteinase reactions. Resolution of the antithrombin conformational change contribution to heparin rate enhancement. J Biol Chem JID -2985121R 1992, 267:12528-12538.
-
(1992)
J Biol Chem JID -2985121R
, vol.267
, pp. 12528-12538
-
-
Olson, S.T.1
Bjork, I.2
Sheffer, R.3
-
18
-
-
0024339952
-
The action of a synthetic pentasaccharide on thrombin generation in whole plasma
-
Beguin S., Choay J., Hemker H.C. The action of a synthetic pentasaccharide on thrombin generation in whole plasma. Thromb Haemost 1989, 61:397-401.
-
(1989)
Thromb Haemost
, vol.61
, pp. 397-401
-
-
Beguin, S.1
Choay, J.2
Hemker, H.C.3
-
19
-
-
2642617786
-
Biochemical and pharmacological properties of SANORG 34006, a potent and long-acting synthetic pentasaccharide
-
Herbert J.M., Herault J.P., Bernat A., et al. Biochemical and pharmacological properties of SANORG 34006, a potent and long-acting synthetic pentasaccharide. Blood 1998, 91:4197-4205.
-
(1998)
Blood
, vol.91
, pp. 4197-4205
-
-
Herbert, J.M.1
Herault, J.P.2
Bernat, A.3
-
20
-
-
0026593425
-
Low molecular weight heparin
-
Hirsh J., Levine M.N. Low molecular weight heparin. Blood 1992, 79:1-17.
-
(1992)
Blood
, vol.79
, pp. 1-17
-
-
Hirsh, J.1
Levine, M.N.2
-
21
-
-
9644265348
-
Pharmacokinetics of UH and LMWH are similar with respect to antithrombin activity
-
Morris T.A., Jacobson A., Marsh J.J., et al. Pharmacokinetics of UH and LMWH are similar with respect to antithrombin activity. Thromb Res 2005, 115:45-51.
-
(2005)
Thromb Res
, vol.115
, pp. 45-51
-
-
Morris, T.A.1
Jacobson, A.2
Marsh, J.J.3
-
22
-
-
33747592631
-
Comparison of fixed-dose weight-adjusted unfractionated heparin and low-molecular-weight heparin for acute treatment of venous thromboembolism
-
Kearon C., Ginsberg J.S., Julian J.A., et al. Comparison of fixed-dose weight-adjusted unfractionated heparin and low-molecular-weight heparin for acute treatment of venous thromboembolism. JAMA 2006, 296:935-942.
-
(2006)
JAMA
, vol.296
, pp. 935-942
-
-
Kearon, C.1
Ginsberg, J.S.2
Julian, J.A.3
-
23
-
-
0035522304
-
Fondaparinux compared with enoxaparin for the prevention of venous thromboembolism after elective major knee surgery
-
Bauer K.A., Eriksson B.I., Lassen M.R., et al. Fondaparinux compared with enoxaparin for the prevention of venous thromboembolism after elective major knee surgery. N Engl J Med JID -0255562 2001, 345:1305-1310.
-
(2001)
N Engl J Med JID -0255562
, vol.345
, pp. 1305-1310
-
-
Bauer, K.A.1
Eriksson, B.I.2
Lassen, M.R.3
-
24
-
-
0035522302
-
Fondaparinux compared with enoxaparin for the prevention of venous thromboembolism after hip-fracture surgery
-
Eriksson B.I., Bauer K.A., Lassen M.R., et al. Fondaparinux compared with enoxaparin for the prevention of venous thromboembolism after hip-fracture surgery. N Engl J Med 2001, 345:1298-1304.
-
(2001)
N Engl J Med
, vol.345
, pp. 1298-1304
-
-
Eriksson, B.I.1
Bauer, K.A.2
Lassen, M.R.3
-
25
-
-
0037129742
-
Postoperative fondaparinux versus preoperative enoxaparin for prevention of venous thromboembolism in elective hip-replacement surgery: a randomised double-blind comparison
-
Lassen M.R., Bauer K.A., Eriksson B.I., et al. Postoperative fondaparinux versus preoperative enoxaparin for prevention of venous thromboembolism in elective hip-replacement surgery: a randomised double-blind comparison. Lancet JID -2985213R 2002, 359:1715-1720.
-
(2002)
Lancet JID -2985213R
, vol.359
, pp. 1715-1720
-
-
Lassen, M.R.1
Bauer, K.A.2
Eriksson, B.I.3
-
26
-
-
0037129720
-
Postoperative fondaparinux versus postoperative enoxaparin for prevention of venous thromboembolism after elective hip-replacement surgery: a randomised double-blind trial
-
Turpie A.G., Bauer K.A., Eriksson B.I., et al. Postoperative fondaparinux versus postoperative enoxaparin for prevention of venous thromboembolism after elective hip-replacement surgery: a randomised double-blind trial. Lancet JID -2985213R 2002, 359:1721-1726.
-
(2002)
Lancet JID -2985213R
, vol.359
, pp. 1721-1726
-
-
Turpie, A.G.1
Bauer, K.A.2
Eriksson, B.I.3
-
27
-
-
0038010814
-
Duration of prophylaxis against venous thromboembolism with fondaparinux after hip fracture surgery: a multicenter, randomized, placebo-controlled, double-blind study
-
Eriksson B.I., Lassen M.R. Duration of prophylaxis against venous thromboembolism with fondaparinux after hip fracture surgery: a multicenter, randomized, placebo-controlled, double-blind study. Arch Intern Med 2003, 163:1337-1342.
-
(2003)
Arch Intern Med
, vol.163
, pp. 1337-1342
-
-
Eriksson, B.I.1
Lassen, M.R.2
-
28
-
-
2542424669
-
Fondaparinux or enoxaparin for the initial treatment of symptomatic deep venous thrombosis: a randomized trial
-
Buller H.R., Davidson B.L., Decousus H., et al. Fondaparinux or enoxaparin for the initial treatment of symptomatic deep venous thrombosis: a randomized trial. Ann Intern Med 2004, 140:867-873.
-
(2004)
Ann Intern Med
, vol.140
, pp. 867-873
-
-
Buller, H.R.1
Davidson, B.L.2
Decousus, H.3
-
29
-
-
0142182561
-
Subcutaneous fondaparinux versus intravenous unfractionated heparin in the initial treatment of pulmonary embolism
-
Buller H.R., Davidson B.L., Decousus H., et al. Subcutaneous fondaparinux versus intravenous unfractionated heparin in the initial treatment of pulmonary embolism. N Engl J Med 2003, 349:1695-1702.
-
(2003)
N Engl J Med
, vol.349
, pp. 1695-1702
-
-
Buller, H.R.1
Davidson, B.L.2
Decousus, H.3
-
30
-
-
78049468403
-
-
Prescribing label for ARIXTRA, NDA no. 021345. Approved 12/23/2009, in Administration FaD (ed)
-
Prescribing label for ARIXTRA, NDA no. 021345. Approved 12/23/2009, in Administration FaD (ed), 2009.
-
(2009)
-
-
-
31
-
-
34250749333
-
Heparin-induced thrombocytopenia associated with fondaparinux
-
[discussion 2655]
-
Warkentin T.E., Maurer B.T., Aster R.H. Heparin-induced thrombocytopenia associated with fondaparinux. N Engl J Med 2007, 356:2653-2655. [discussion 2655].
-
(2007)
N Engl J Med
, vol.356
, pp. 2653-2655
-
-
Warkentin, T.E.1
Maurer, B.T.2
Aster, R.H.3
-
32
-
-
43749116913
-
Fondaparinux-related thrombocytopenia in a previous low-molecular-weight heparin (LMWH)-induced heparin-induced thrombocytopenia (HIT)
-
Rota E., Bazzan M., Fantino G. Fondaparinux-related thrombocytopenia in a previous low-molecular-weight heparin (LMWH)-induced heparin-induced thrombocytopenia (HIT). Thromb Haemost 2008, 99:779-781.
-
(2008)
Thromb Haemost
, vol.99
, pp. 779-781
-
-
Rota, E.1
Bazzan, M.2
Fantino, G.3
-
33
-
-
0037239007
-
Evaluation of the pharmacological properties and clinical results of the synthetic pentasaccharide (fondaparinux)
-
Samama M.M., Gerotziafas G.T. Evaluation of the pharmacological properties and clinical results of the synthetic pentasaccharide (fondaparinux). Thromb Res 2003, 109:1-11.
-
(2003)
Thromb Res
, vol.109
, pp. 1-11
-
-
Samama, M.M.1
Gerotziafas, G.T.2
-
34
-
-
34548768174
-
Idraparinux versus standard therapy for venous thromboembolic disease
-
Buller H.R., Cohen A.T., Davidson B., et al. Idraparinux versus standard therapy for venous thromboembolic disease. N Engl J Med 2007, 357:1094-1104.
-
(2007)
N Engl J Med
, vol.357
, pp. 1094-1104
-
-
Buller, H.R.1
Cohen, A.T.2
Davidson, B.3
-
35
-
-
34548712332
-
Extended prophylaxis of venous thromboembolism with idraparinux
-
Buller H.R., Cohen A.T., Davidson B., et al. Extended prophylaxis of venous thromboembolism with idraparinux. N Engl J Med 2007, 357:1105-1112.
-
(2007)
N Engl J Med
, vol.357
, pp. 1105-1112
-
-
Buller, H.R.1
Cohen, A.T.2
Davidson, B.3
-
36
-
-
77952703086
-
Reversibility of the anti-FXa activity of idrabiotaparinux (biotinylated idraparinux) by intravenous avidin infusion
-
Paty I., Trellu M., Destors J.M., et al. Reversibility of the anti-FXa activity of idrabiotaparinux (biotinylated idraparinux) by intravenous avidin infusion. J Thromb Haemost 2010, 8(4):722-729.
-
(2010)
J Thromb Haemost
, vol.8
, Issue.4
, pp. 722-729
-
-
Paty, I.1
Trellu, M.2
Destors, J.M.3
-
37
-
-
0037171819
-
Structure-based design of novel potent nonpeptide thrombin inhibitors
-
Hauel N.H., Nar H., Priepke H., et al. Structure-based design of novel potent nonpeptide thrombin inhibitors. J Med Chem 2002, 45:1757-1766.
-
(2002)
J Med Chem
, vol.45
, pp. 1757-1766
-
-
Hauel, N.H.1
Nar, H.2
Priepke, H.3
-
38
-
-
34548575058
-
Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: a randomised, double-blind, non-inferiority trial
-
Eriksson B.I., Dahl O.E., Rosencher N., et al. Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: a randomised, double-blind, non-inferiority trial. Lancet 2007, 370:949-956.
-
(2007)
Lancet
, vol.370
, pp. 949-956
-
-
Eriksson, B.I.1
Dahl, O.E.2
Rosencher, N.3
-
39
-
-
35449007749
-
Oral dabigatran etexilate vs. subcutaneous enoxaparin for the prevention of venous thromboembolism after total knee replacement: the RE-MODEL randomized trial
-
Eriksson B.I., Dahl O.E., Rosencher N., et al. Oral dabigatran etexilate vs. subcutaneous enoxaparin for the prevention of venous thromboembolism after total knee replacement: the RE-MODEL randomized trial. J Thromb Haemost 2007, 5:2178-2185.
-
(2007)
J Thromb Haemost
, vol.5
, pp. 2178-2185
-
-
Eriksson, B.I.1
Dahl, O.E.2
Rosencher, N.3
-
40
-
-
57649123692
-
Oral thrombin inhibitor dabigatran etexilate vs North American enoxaparin regimen for prevention of venous thromboembolism after knee arthroplasty surgery
-
Ginsberg J.S., Davidson B.L., Comp P.C., et al. Oral thrombin inhibitor dabigatran etexilate vs North American enoxaparin regimen for prevention of venous thromboembolism after knee arthroplasty surgery. J Arthroplasty 2009, 24:1-9.
-
(2009)
J Arthroplasty
, vol.24
, pp. 1-9
-
-
Ginsberg, J.S.1
Davidson, B.L.2
Comp, P.C.3
-
41
-
-
71849117615
-
Dabigatran versus warfarin in the treatment of acute venous thromboembolism
-
Schulman S., Kearon C., Kakkar A.K., et al. Dabigatran versus warfarin in the treatment of acute venous thromboembolism. N Engl J Med 2009, 361:2342-2352.
-
(2009)
N Engl J Med
, vol.361
, pp. 2342-2352
-
-
Schulman, S.1
Kearon, C.2
Kakkar, A.K.3
-
42
-
-
0142182558
-
Secondary prevention of venous thromboembolism with the oral direct thrombin inhibitor ximelagatran
-
Schulman S., Wahlander K., Lundstrom T., et al. Secondary prevention of venous thromboembolism with the oral direct thrombin inhibitor ximelagatran. N Engl J Med 2003, 349:1713-1721.
-
(2003)
N Engl J Med
, vol.349
, pp. 1713-1721
-
-
Schulman, S.1
Wahlander, K.2
Lundstrom, T.3
-
43
-
-
24944536065
-
Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor
-
Roehrig S., Straub A., Pohlmann J., et al. Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor. J Med Chem 2005, 48:5900-5908.
-
(2005)
J Med Chem
, vol.48
, pp. 5900-5908
-
-
Roehrig, S.1
Straub, A.2
Pohlmann, J.3
-
44
-
-
22844442726
-
In vitro and in vivo studies of the novel antithrombotic agent BAY 59-7939-an oral, direct Factor Xa inhibitor
-
Perzborn E., Strassburger J., Wilmen A., et al. In vitro and in vivo studies of the novel antithrombotic agent BAY 59-7939-an oral, direct Factor Xa inhibitor. J Thromb Haemost 2005, 3:514-521.
-
(2005)
J Thromb Haemost
, vol.3
, pp. 514-521
-
-
Perzborn, E.1
Strassburger, J.2
Wilmen, A.3
-
45
-
-
51349095537
-
Population pharmacokinetics and pharmacodynamics of once- and twice-daily rivaroxaban for the prevention of venous thromboembolism in patients undergoing total hip replacement
-
Mueck W., Borris L.C., Dahl O.E., et al. Population pharmacokinetics and pharmacodynamics of once- and twice-daily rivaroxaban for the prevention of venous thromboembolism in patients undergoing total hip replacement. Thromb Haemost 2008, 100:453-461.
-
(2008)
Thromb Haemost
, vol.100
, pp. 453-461
-
-
Mueck, W.1
Borris, L.C.2
Dahl, O.E.3
-
46
-
-
42949123582
-
Population pharmacokinetics and pharmacodynamics of rivaroxaban-an oral, direct factor Xa inhibitor-in patients undergoing major orthopaedic surgery
-
Mueck W., Eriksson B.I., Bauer K.A., et al. Population pharmacokinetics and pharmacodynamics of rivaroxaban-an oral, direct factor Xa inhibitor-in patients undergoing major orthopaedic surgery. Clin Pharmacokinet 2008, 47:203-216.
-
(2008)
Clin Pharmacokinet
, vol.47
, pp. 203-216
-
-
Mueck, W.1
Eriksson, B.I.2
Bauer, K.A.3
-
47
-
-
45949099359
-
Rivaroxaban versus enoxaparin for thromboprophylaxis after hip arthroplasty
-
Eriksson B.I., Borris L.C., Friedman R.J., et al. Rivaroxaban versus enoxaparin for thromboprophylaxis after hip arthroplasty. N Engl J Med 2008, 358:2765-2775.
-
(2008)
N Engl J Med
, vol.358
, pp. 2765-2775
-
-
Eriksson, B.I.1
Borris, L.C.2
Friedman, R.J.3
-
48
-
-
46049106502
-
Extended duration rivaroxaban versus short-term enoxaparin for the prevention of venous thromboembolism after total hip arthroplasty: a double-blind, randomised controlled trial
-
Kakkar A.K., Brenner B., Dahl O.E., et al. Extended duration rivaroxaban versus short-term enoxaparin for the prevention of venous thromboembolism after total hip arthroplasty: a double-blind, randomised controlled trial. Lancet 2008, 372:31-39.
-
(2008)
Lancet
, vol.372
, pp. 31-39
-
-
Kakkar, A.K.1
Brenner, B.2
Dahl, O.E.3
-
49
-
-
45949103416
-
Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty
-
Lassen M.R., Ageno W., Borris L.C., et al. Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty. N Engl J Med 2008, 358:2776-2786.
-
(2008)
N Engl J Med
, vol.358
, pp. 2776-2786
-
-
Lassen, M.R.1
Ageno, W.2
Borris, L.C.3
-
50
-
-
34447317298
-
Treatment of proximal deep-vein thrombosis with the oral direct factor Xa inhibitor rivaroxaban (BAY 59-7939): the ODIXa-DVT (Oral Direct Factor Xa Inhibitor BAY 59-7939 in Patients With Acute Symptomatic Deep-Vein Thrombosis) study
-
Agnelli G., Gallus A., Goldhaber S.Z., et al. Treatment of proximal deep-vein thrombosis with the oral direct factor Xa inhibitor rivaroxaban (BAY 59-7939): the ODIXa-DVT (Oral Direct Factor Xa Inhibitor BAY 59-7939 in Patients With Acute Symptomatic Deep-Vein Thrombosis) study. Circulation 2007, 116:180-187.
-
(2007)
Circulation
, vol.116
, pp. 180-187
-
-
Agnelli, G.1
Gallus, A.2
Goldhaber, S.Z.3
-
51
-
-
53849123533
-
A dose-ranging study evaluating once-daily oral administration of the factor Xa inhibitor rivaroxaban in the treatment of patients with acute symptomatic deep vein thrombosis: the Einstein-DVT Dose-Ranging Study
-
Buller H.R., Lensing A.W., Prins M.H., et al. A dose-ranging study evaluating once-daily oral administration of the factor Xa inhibitor rivaroxaban in the treatment of patients with acute symptomatic deep vein thrombosis: the Einstein-DVT Dose-Ranging Study. Blood 2008, 112:2242-2247.
-
(2008)
Blood
, vol.112
, pp. 2242-2247
-
-
Buller, H.R.1
Lensing, A.W.2
Prins, M.H.3
-
52
-
-
35848929515
-
Discovery of 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrah ydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide (apixaban, BMS-562247), a highly potent, selective, efficacious, and orally bioavailable inhibitor of blood coagulation factor Xa
-
Pinto D.J., Orwat M.J., Koch S., et al. Discovery of 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrah ydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide (apixaban, BMS-562247), a highly potent, selective, efficacious, and orally bioavailable inhibitor of blood coagulation factor Xa. J Med Chem 2007, 50:5339-5356.
-
(2007)
J Med Chem
, vol.50
, pp. 5339-5356
-
-
Pinto, D.J.1
Orwat, M.J.2
Koch, S.3
-
53
-
-
58149458160
-
Apixaban metabolism and pharmacokinetics after oral administration to humans
-
Raghavan N., Frost C.E., Yu Z., et al. Apixaban metabolism and pharmacokinetics after oral administration to humans. Drug Metab Dispos 2009, 37:74-81.
-
(2009)
Drug Metab Dispos
, vol.37
, pp. 74-81
-
-
Raghavan, N.1
Frost, C.E.2
Yu, Z.3
-
54
-
-
68249158084
-
Apixaban or enoxaparin for thromboprophylaxis after knee replacement
-
Lassen M.R., Raskob G.E., Gallus A., et al. Apixaban or enoxaparin for thromboprophylaxis after knee replacement. N Engl J Med 2009, 361:594-604.
-
(2009)
N Engl J Med
, vol.361
, pp. 594-604
-
-
Lassen, M.R.1
Raskob, G.E.2
Gallus, A.3
-
55
-
-
47649098524
-
Efficacy and safety of the oral direct factor Xa inhibitor apixaban for symptomatic deep vein thrombosis. The Botticelli DVT dose-ranging study
-
Buller H., Deitchman D., Prins M., et al. Efficacy and safety of the oral direct factor Xa inhibitor apixaban for symptomatic deep vein thrombosis. The Botticelli DVT dose-ranging study. J Thromb Haemost 2008, 6:1313-1318.
-
(2008)
J Thromb Haemost
, vol.6
, pp. 1313-1318
-
-
Buller, H.1
Deitchman, D.2
Prins, M.3
-
56
-
-
63149141508
-
Discovery of betrixaban (PRT054021), N-(5-chloropyridin-2-yl)-2-(4-(N, N-dimethylcarbamimidoyl)benzamido)-5-meth oxybenzamide, a highly potent, selective, and orally efficacious factor Xa inhibitor
-
Zhang P., Huang W., Wang L., et al. Discovery of betrixaban (PRT054021), N-(5-chloropyridin-2-yl)-2-(4-(N, N-dimethylcarbamimidoyl)benzamido)-5-meth oxybenzamide, a highly potent, selective, and orally efficacious factor Xa inhibitor. Bioorg Med Chem Lett 2009, 19:2179-2185.
-
(2009)
Bioorg Med Chem Lett
, vol.19
, pp. 2179-2185
-
-
Zhang, P.1
Huang, W.2
Wang, L.3
-
57
-
-
60849097858
-
A randomized evaluation of betrixaban, an oral factor Xa inhibitor, for prevention of thromboembolic events after total knee replacement (EXPERT)
-
Turpie A.G., Bauer K.A., Davidson B.L., et al. A randomized evaluation of betrixaban, an oral factor Xa inhibitor, for prevention of thromboembolic events after total knee replacement (EXPERT). Thromb Haemost 2009, 101:68-76.
-
(2009)
Thromb Haemost
, vol.101
, pp. 68-76
-
-
Turpie, A.G.1
Bauer, K.A.2
Davidson, B.L.3
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