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Volumn 115, Issue 1-2, 2005, Pages 45-51

Pharmacokinetics of UH and LMWH are similar with respect to antithrombin activity

Author keywords

Anticoagulation; Heparin; Low molecular weight heparin; Pharmacokinetics

Indexed keywords

DALTEPARIN; ENOXAPARIN; HEPARIN; LOW MOLECULAR WEIGHT HEPARIN; TINZAPARIN; WARFARIN;

EID: 9644265348     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2004.07.010     Document Type: Article
Times cited : (16)

References (33)
  • 1
    • 0035125568 scopus 로고    scopus 로고
    • Antithrombotic therapy for venous thromboembolic disease
    • T.M. Hyers, G. Agnelli, R.D. Hull, T.A. Morris, M. Samama, and V. Tapson Antithrombotic therapy for venous thromboembolic disease Chest 119 1 Suppl 2001 176S 193S [JID-0231335]
    • (2001) Chest , vol.119 , Issue.1
    • Hyers, T.M.1    Agnelli, G.2    Hull, R.D.3    Morris, T.A.4    Samama, M.5    Tapson, V.6
  • 2
    • 0031856036 scopus 로고    scopus 로고
    • Use of an algorithm for administering subcutaneous heparin in the treatment of deep venous thrombosis
    • P. Prandoni, P. Bagatella, E. Bernardi, B. Girolami, L. Rossi, and L. Scarano Use of an algorithm for administering subcutaneous heparin in the treatment of deep venous thrombosis Ann. Intern. Medicin. 129 4 1998 299 302
    • (1998) Ann. Intern. Medicin. , vol.129 , Issue.4 , pp. 299-302
    • Prandoni, P.1    Bagatella, P.2    Bernardi, E.3    Girolami, B.4    Rossi, L.5    Scarano, L.6
  • 3
    • 0026593425 scopus 로고
    • Low molecular weight heparin
    • J. Hirsh, and M.N. Levine Low molecular weight heparin Blood 79 1 1992 1 17
    • (1992) Blood , vol.79 , Issue.1 , pp. 1-17
    • Hirsh, J.1    Levine, M.N.2
  • 4
    • 0034325120 scopus 로고    scopus 로고
    • Anti-thrombotic efficacies of enoxaparin, dalteparin, and unfractionated heparin in venous thromboembolism
    • T.A. Morris, J.J. Marsh, R. Konopka, C.A. Pedersen, and PG. Chiles Anti-thrombotic efficacies of enoxaparin, dalteparin, and unfractionated heparin in venous thromboembolism Thromb. Res. 100 3 2000 185 194 [JID-0326377]
    • (2000) Thromb. Res. , vol.100 , Issue.3 , pp. 185-194
    • Morris, T.A.1    Marsh, J.J.2    Konopka, R.3    Pedersen, C.A.4    Chiles, P.G.5
  • 5
    • 0027410948 scopus 로고
    • A comparison of the antithrombotic effects of heparin and of low molecular weight heparins with increasing antifactor xa/antifactor iia ratio in the rabbit
    • D. Carrie, C. Caranobe, and B. Boneu A comparison of the antithrombotic effects of heparin and of low molecular weight heparins with increasing antifactor xa/antifactor iia ratio in the rabbit Br. J. Hematol. 83 1993 622 626
    • (1993) Br. J. Hematol. , vol.83 , pp. 622-626
    • Carrie, D.1    Caranobe, C.2    Boneu, B.3
  • 6
    • 0027399508 scopus 로고
    • Factor xa inhibition: Correlation between the plasma levels of anti-xa activity and occurrence of thrombosis and haemorrhage
    • A. Leizorovicz, L. Bara, M.M. Samama, and M.C. Haugh Factor xa inhibition: correlation between the plasma levels of anti-xa activity and occurrence of thrombosis and haemorrhage Haemostasis 23 Suppl 1 1993 89 98
    • (1993) Haemostasis , vol.23 , Issue.1 , pp. 89-98
    • Leizorovicz, A.1    Bara, L.2    Samama, M.M.3    Haugh, M.C.4
  • 7
    • 0028346093 scopus 로고
    • Pharmacokinetics and pharmacodynamics of a low molecular weight heparin (enoxaparin) after subcutaneous injection, comparison with unfractionated heparin-a three way cross over study in human volunteers
    • A.V. Bendetowicz, S. Beguin, H. Caplain, and H.C. Hemker Pharmacokinetics and pharmacodynamics of a low molecular weight heparin (enoxaparin) after subcutaneous injection, comparison with unfractionated heparin-a three way cross over study in human volunteers Thromb. Haemost. 71 1994 305 313
    • (1994) Thromb. Haemost. , vol.71 , pp. 305-313
    • Bendetowicz, A.V.1    Beguin, S.2    Caplain, H.3    Hemker, H.C.4
  • 9
    • 0026663920 scopus 로고
    • Treatment doses of different low molecular weight heparins and unfractionated heparins differ in their anticoagulating effects in respect to aptt, heptest, anti-iia- and anti-xa-activity
    • E. Lindhoff-Last, G. Mosch, and H.K. Breddin Treatment doses of different low molecular weight heparins and unfractionated heparins differ in their anticoagulating effects in respect to aptt, heptest, anti-iia- and anti-xa-activity Lab. Med. 16 1992 174 177
    • (1992) Lab. Med. , vol.16 , pp. 174-177
    • Lindhoff-Last, E.1    Mosch, G.2    Breddin, H.K.3
  • 10
    • 0030958260 scopus 로고    scopus 로고
    • Dosage, anticoagulant, and antithrombotic effects of heparin and low-molecular-weight heparin in the treatment of deep vein thrombosis
    • J. Harenberg, G. Stehle, M. Blauth, K. Huck, K. Mall, and D.L. Heene Dosage, anticoagulant, and antithrombotic effects of heparin and low-molecular-weight heparin in the treatment of deep vein thrombosis Semin. Thromb. Hemost. 23 1 1997 83 90
    • (1997) Semin. Thromb. Hemost. , vol.23 , Issue.1 , pp. 83-90
    • Harenberg, J.1    Stehle, G.2    Blauth, M.3    Huck, K.4    Mall, K.5    Heene, D.L.6
  • 11
    • 0343484317 scopus 로고    scopus 로고
    • Conjectures and refutations on the mode of action of heparins. the limited importance of anti-factor xa activity as a pharmaceutical mechanism and a yardstick for therapy
    • S. Beguin, D. Welzel, R. Al Dieri, and H.C. Hemker Conjectures and refutations on the mode of action of heparins. The limited importance of anti-factor xa activity as a pharmaceutical mechanism and a yardstick for therapy Haemostasis 29 2-3 1999 170 178 [JID-0371574]
    • (1999) Haemostasis , vol.29 , Issue.23 , pp. 170-178
    • Beguin, S.1    Welzel, D.2    Al Dieri, R.3    Hemker, H.C.4
  • 12
    • 0028072085 scopus 로고
    • Inhibition by heparin of the human blood coagulation intrinsic pathway factor x activator
    • R.T. Barrow, E.T. Parker, S. Krishnaswamy, and P. Lollar Inhibition by heparin of the human blood coagulation intrinsic pathway factor x activator J. Biol. Chem. 269 43 1994 26796 26800
    • (1994) J. Biol. Chem. , vol.269 , Issue.43 , pp. 26796-26800
    • Barrow, R.T.1    Parker, E.T.2    Krishnaswamy, S.3    Lollar, P.4
  • 13
    • 0029848050 scopus 로고    scopus 로고
    • The relation between the activated partial thromboplastin time response and recurrence in patients with venous thrombosis treated with continuous intravenous heparin
    • S. Anand, J.S. Ginsberg, C. Kearon, M. Gent, and J. Hirsh The relation between the activated partial thromboplastin time response and recurrence in patients with venous thrombosis treated with continuous intravenous heparin Arch. Intern. Med. 156 15 1996 1677 1681
    • (1996) Arch. Intern. Med. , vol.156 , Issue.15 , pp. 1677-1681
    • Anand, S.1    Ginsberg, J.S.2    Kearon, C.3    Gent, M.4    Hirsh, J.5
  • 14
    • 0033610234 scopus 로고    scopus 로고
    • Recurrent venous thrombosis and heparin therapy: An evaluation of the importance of early activated partial thromboplastin times
    • S.S. Anand, S. Bates, J.S. Ginsberg, M. Levine, H. Buller, and M. Prins Recurrent venous thrombosis and heparin therapy: an evaluation of the importance of early activated partial thromboplastin times Arch. Intern. Med. 159 17 1999 2029 2032
    • (1999) Arch. Intern. Med. , vol.159 , Issue.17 , pp. 2029-2032
    • Anand, S.S.1    Bates, S.2    Ginsberg, J.S.3    Levine, M.4    Buller, H.5    Prins, M.6
  • 15
    • 1842369696 scopus 로고    scopus 로고
    • Low-molecular-weight heparin in the treatment of patients with venous thromboembolism. the Columbus Investigators
    • Low-molecular-weight heparin in the treatment of patients with venous thromboembolism. The Columbus Investigators N. Engl. J. Med. 337 10 1997 657 662
    • (1997) N. Engl. J. Med. , vol.337 , Issue.10 , pp. 657-662
  • 16
    • 0032860918 scopus 로고    scopus 로고
    • Comparison of low-molecular-weight heparin, administered primarily at home, with unfractionated heparin, administered in hospital, and subcutaneous heparin, administered at home for deep-vein thrombosis
    • G. Belcaro, A.N. Nicolaides, M.R. Cesarone, G. Laurora, L. Incandela, and A. Barsotti Comparison of low-molecular-weight heparin, administered primarily at home, with unfractionated heparin, administered in hospital, and subcutaneous heparin, administered at home for deep-vein thrombosis Angiology 50 1999 781 787
    • (1999) Angiology , vol.50 , pp. 781-787
    • Belcaro, G.1    Nicolaides, A.N.2    Cesarone, M.R.3    Laurora, G.4    Incandela, L.5    Barsotti, A.6
  • 17
    • 0029842386 scopus 로고    scopus 로고
    • Once-daily subcutaneous dalteparin, a low molecular weight heparin, for the initial treatment of acute deep vein thrombosis
    • J.N. Fiessinger, M. Lopez-Fernandez, E. Gatterer, S. Granqvist, A. Kher, and C.G. Olsson Once-daily subcutaneous dalteparin, a low molecular weight heparin, for the initial treatment of acute deep vein thrombosis Thromb. Haemost. 76 2 1996 195 199
    • (1996) Thromb. Haemost. , vol.76 , Issue.2 , pp. 195-199
    • Fiessinger, J.N.1    Lopez-Fernandez, M.2    Gatterer, E.3    Granqvist, S.4    Kher, A.5    Olsson, C.G.6
  • 18
    • 0031755859 scopus 로고    scopus 로고
    • Efficacy of a low molecular weight heparin administered intravenously or subcutaneously in comparison with intravenous unfractionated heparin in the treatment of deep venous thrombosis. Certoparin-Study Group
    • C.M. Kirchmaier, H. Wolf, H. Scheafer, B. Ehlers, and H.K. Breddin Efficacy of a low molecular weight heparin administered intravenously or subcutaneously in comparison with intravenous unfractionated heparin in the treatment of deep venous thrombosis. Certoparin-Study Group Int. Angiol. 17 3 1998 135 145
    • (1998) Int. Angiol. , vol.17 , Issue.3 , pp. 135-145
    • Kirchmaier, C.M.1    Wolf, H.2    Scheafer, H.3    Ehlers, B.4    Breddin, H.K.5
  • 19
    • 0029969612 scopus 로고    scopus 로고
    • Treatment of venous thrombosis with intravenous unfractionated heparin administered in the hospital as compared with subcutaneous low-molecular-weight heparin administered at home. the Tasman Study Group [see comments] [published erratum appears in N. Engl. J. Med. 1997 Oct 23;337(17):1251]
    • M.M. Koopman, P. Prandoni, F. Piovella, P.A. Ockelford, D.P. Brandjes, and J. van der Meer Treatment of venous thrombosis with intravenous unfractionated heparin administered in the hospital as compared with subcutaneous low-molecular-weight heparin administered at home. The Tasman Study Group [see comments] [published erratum appears in N. Engl. J. Med. 1997 Oct 23;337(17):1251] N. Engl. J. Med. 334 11 1996 682 687
    • (1996) N. Engl. J. Med. , vol.334 , Issue.11 , pp. 682-687
    • Koopman, M.M.1    Prandoni, P.2    Piovella, F.3    Ockelford, P.A.4    Brandjes, D.P.5    Van Der Meer, J.6
  • 20
    • 0006590545 scopus 로고    scopus 로고
    • A comparison of low-molecular-weight heparin administered primarily at home with unfractionated heparin administered in the hospital for proximal deep-vein thrombosis [see comments]
    • M. Levine, M. Gent, J. Hirsh, J. Leclerc, D. Anderson, and J. Weitz A comparison of low-molecular-weight heparin administered primarily at home with unfractionated heparin administered in the hospital for proximal deep-vein thrombosis [see comments] N. Engl. J. Med. 334 11 1996 677 681
    • (1996) N. Engl. J. Med. , vol.334 , Issue.11 , pp. 677-681
    • Levine, M.1    Gent, M.2    Hirsh, J.3    Leclerc, J.4    Anderson, D.5    Weitz, J.6
  • 21
    • 0027931443 scopus 로고
    • Comparison of once-daily subcutaneous fragmin with continuous intravenous unfractionated heparin in the treatment of deep vein thrombosis
    • P. Lindmarker, M. Holmstreom, S. Granqvist, H. Johnsson, and D. Lockner Comparison of once-daily subcutaneous fragmin with continuous intravenous unfractionated heparin in the treatment of deep vein thrombosis Thromb. Haemost. 72 2 1994 186 190
    • (1994) Thromb. Haemost. , vol.72 , Issue.2 , pp. 186-190
    • Lindmarker, P.1    Holmstreom, M.2    Granqvist, S.3    Johnsson, H.4    Lockner, D.5
  • 22
    • 9544233577 scopus 로고    scopus 로고
    • A multicentre comparison of once-daily subcutaneous dalteparin (low molecular weight heparin) and continuous intravenous heparin in the treatment of deep vein thrombosis
    • K. Luomanmeaki, S. Grankvist, C. Hallert, I. Jauro, K. Ketola, and H.C. Kim A multicentre comparison of once-daily subcutaneous dalteparin (low molecular weight heparin) and continuous intravenous heparin in the treatment of deep vein thrombosis J. Int. Med. 240 2 1996 85 92
    • (1996) J. Int. Med. , vol.240 , Issue.2 , pp. 85-92
    • Luomanmeaki, K.1    Grankvist, S.2    Hallert, C.3    Jauro, I.4    Ketola, K.5    Kim, H.C.6
  • 23
    • 0035814834 scopus 로고    scopus 로고
    • Subcutaneous enoxaparin once or twice daily compared with intravenous unfractionated heparin for treatment of venous thromboembolic disease
    • G. Merli, T.E. Spiro, C.G. Olsson, U. Abildgaard, B.L. Davidson, and A. Eldor Subcutaneous enoxaparin once or twice daily compared with intravenous unfractionated heparin for treatment of venous thromboembolic disease Ann. Intern. Med. 134 3 2001 191 202
    • (2001) Ann. Intern. Med. , vol.134 , Issue.3 , pp. 191-202
    • Merli, G.1    Spiro, T.E.2    Olsson, C.G.3    Abildgaard, U.4    Davidson, B.L.5    Eldor, A.6
  • 24
    • 0029565163 scopus 로고
    • Subcutaneous low-molecular-weight heparin fragmin versus intravenous unfractionated heparin in the treatment of acute non massive pulmonary embolism: An open randomized pilot study
    • G. Meyer, F. Brenot, G. Pacouret, G. Simonneau, J. Gillet, and B. Charbonnier Subcutaneous low-molecular-weight heparin fragmin versus intravenous unfractionated heparin in the treatment of acute non massive pulmonary embolism: an open randomized pilot study Thromb. Haemost. 74 6 1995 1432 1435
    • (1995) Thromb. Haemost. , vol.74 , Issue.6 , pp. 1432-1435
    • Meyer, G.1    Brenot, F.2    Pacouret, G.3    Simonneau, G.4    Gillet, J.5    Charbonnier, B.6
  • 25
    • 0026569416 scopus 로고
    • Comparison of subcutaneous low-molecular-weight heparin with intravenous standard heparin in proximal deep-vein thrombosis
    • P. Prandoni, A.W. Lensing, H.R. Buller, M. Carta, A. Cogo, and M. Vigo Comparison of subcutaneous low-molecular-weight heparin with intravenous standard heparin in proximal deep-vein thrombosis Lancet 339 8791 1992 441 445
    • (1992) Lancet , vol.339 , Issue.8791 , pp. 441-445
    • Prandoni, P.1    Lensing, A.W.2    Buller, H.R.3    Carta, M.4    Cogo, A.5    Vigo, M.6
  • 26
    • 8544273238 scopus 로고    scopus 로고
    • A comparison of low-molecular-weight heparin with unfractionated heparin for acute pulmonary embolism. the Thesee Study Group. Tinzaparine ou heparine standard: Evaluations dans l'embolie pulmonaire
    • G. Simonneau, H. Sors, B. Charbonnier, Y. Page, J.P. Laaban, and R. Azarian A comparison of low-molecular-weight heparin with unfractionated heparin for acute pulmonary embolism. The Thesee Study Group. Tinzaparine ou heparine standard: evaluations dans l'embolie pulmonaire N. Engl. J. Med. 337 10 1997 663 669
    • (1997) N. Engl. J. Med. , vol.337 , Issue.10 , pp. 663-669
    • Simonneau, G.1    Sors, H.2    Charbonnier, B.3    Page, Y.4    Laaban, J.P.5    Azarian, R.6
  • 27
    • 0026576068 scopus 로고
    • Subcutaneous low-molecular-weight heparin compared with continuous intravenous heparin in the treatment of proximal-vein thrombosis [see comments]
    • R.D. Hull, G.E. Raskob, G.F. Pineo, D. Green, A.A. Trowbridge, and C.G. Elliott Subcutaneous low-molecular-weight heparin compared with continuous intravenous heparin in the treatment of proximal-vein thrombosis [see comments] N. Engl. J. Med. 326 15 1992 975 982
    • (1992) N. Engl. J. Med. , vol.326 , Issue.15 , pp. 975-982
    • Hull, R.D.1    Raskob, G.E.2    Pineo, G.F.3    Green, D.4    Trowbridge, A.A.5    Elliott, C.G.6
  • 28
    • 0019931840 scopus 로고
    • Subcutaneous administration of heparin. a randomised comparison with intravenous administration of heparin to patients with deep-vein thrombosis
    • G. Andersson, B. Fagrell, K. Holmgren, H. Johnsson, B. Ljungberg, and E. Nilsson Subcutaneous administration of heparin. A randomised comparison with intravenous administration of heparin to patients with deep-vein thrombosis Thromb. Res. 27 1982 631 639
    • (1982) Thromb. Res. , vol.27 , pp. 631-639
    • Andersson, G.1    Fagrell, B.2    Holmgren, K.3    Johnsson, H.4    Ljungberg, B.5    Nilsson, E.6
  • 29
    • 0029034399 scopus 로고
    • Comparing subcutaneous danaparoid with intravenous unfractionated heparin for the treatment of venous thromboembolism. a randomized controlled trial [see comments]
    • H.W. de Valk, J.D. Banga, J.W. Wester, C.B. Brouwer, M.W. van Hessen, and O.J. Meuwissen Comparing subcutaneous danaparoid with intravenous unfractionated heparin for the treatment of venous thromboembolism. A randomized controlled trial [see comments] Ann. Intern. Med. 123 1 1995 1 9
    • (1995) Ann. Intern. Med. , vol.123 , Issue.1 , pp. 1-9
    • De Valk, H.W.1    Banga, J.D.2    Wester, J.W.3    Brouwer, C.B.4    Van Hessen, M.W.5    Meuwissen, O.J.6
  • 30
    • 0023275245 scopus 로고
    • Adjusted subcutaneous heparin or continuous intravenous heparin in patients with acute deep vein thrombosis. a randomized trial
    • D.J. Doyle, A.G. Turpie, J. Hirsh, C. Best, D. Kinch, and M.N. Levine Adjusted subcutaneous heparin or continuous intravenous heparin in patients with acute deep vein thrombosis. A randomized trial Ann. Intern. Med. 107 1987 441 445
    • (1987) Ann. Intern. Med. , vol.107 , pp. 441-445
    • Doyle, D.J.1    Turpie, A.G.2    Hirsh, J.3    Best, C.4    Kinch, D.5    Levine, M.N.6
  • 31
    • 0020035103 scopus 로고
    • Adjusted dose subcutaneous heparin versus warfarin sodium in the long-term treatment of venous thrombosis
    • R. Hull, T. Delmore, C. Carter, J. Hirsh, E. Genton, and M. Gent Adjusted dose subcutaneous heparin versus warfarin sodium in the long-term treatment of venous thrombosis N. Engl. J. Med. 306 4 1982 189 194
    • (1982) N. Engl. J. Med. , vol.306 , Issue.4 , pp. 189-194
    • Hull, R.1    Delmore, T.2    Carter, C.3    Hirsh, J.4    Genton, E.5    Gent, M.6
  • 32
    • 0024405893 scopus 로고
    • Unfractionated heparin and cy 216: Pharmacokinetics and bioavailabilities of the antifactor xa and iia effects after intravenous and subcutaneous injection in the rabbit
    • L. Briant, C. Caranobe, S. Saivin, P. Sie, B. Bayrou, and G. Houin Unfractionated heparin and cy 216: pharmacokinetics and bioavailabilities of the antifactor xa and iia effects after intravenous and subcutaneous injection in the rabbit Thromb. Haemost. 61 1989 348 353
    • (1989) Thromb. Haemost. , vol.61 , pp. 348-353
    • Briant, L.1    Caranobe, C.2    Saivin, S.3    Sie, P.4    Bayrou, B.5    Houin, G.6
  • 33
    • 0024240522 scopus 로고
    • The antithrombotic activity and pharmacokinetics of enoxaparine, a low molecular weight heparin, in humans given single subcutaneous doses of 20 to 80 mg
    • A.M. Frydman, L. Bara, Y. Le Roux, M. Woler, F. Chauliac, and M.M. Samama The antithrombotic activity and pharmacokinetics of enoxaparine, a low molecular weight heparin, in humans given single subcutaneous doses of 20 to 80 mg J. Clin. Pharmacol. 28 1988 609 618
    • (1988) J. Clin. Pharmacol. , vol.28 , pp. 609-618
    • Frydman, A.M.1    Bara, L.2    Le Roux, Y.3    Woler, M.4    Chauliac, F.5    Samama, M.M.6


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