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Volumn 109, Issue 2, 2000, Pages 336-341

Affinity purification of heparin-dependent antibodies to platelet factor 4 developed in heparin-induced thrombocytopenia: Biological characteristics and effects on platelet activation

Author keywords

Antibodies to heparin PF4; Heparin induced thrombocytopenia; Platelet activation

Indexed keywords

ANTIBODY; HEPARIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; SEROTONIN; THROMBOCYTE FACTOR 4;

EID: 0034079490     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2000.02034.x     Document Type: Article
Times cited : (61)

References (21)
  • 1
    • 0026638091 scopus 로고
    • Platelet factor 4 complexed to heparin is the target for antibodies generated in heparin-induced thrombocytopenia
    • Amiral, J., Bridey, F., Dreyfus, M., Vissac, A., Fressinaud, E., Wolf, M. & Meyer, D. (1992) Platelet factor 4 complexed to heparin is the target for antibodies generated in heparin-induced thrombocytopenia. Thrombosis and Haemostasis, 68, 95-96.
    • (1992) Thrombosis and Haemostasis , vol.68 , pp. 95-96
    • Amiral, J.1    Bridey, F.2    Dreyfus, M.3    Vissac, A.4    Fressinaud, E.5    Wolf, M.6    Meyer, D.7
  • 3
    • 0029878458 scopus 로고    scopus 로고
    • Pathogenicity of IgA and/or IgM antibodies to heparin-PF4 complexes in patients with heparin-induced thrombocytopenia
    • Amiral, J., Wolf, M., Fischer, A.M., Boyer-Neumann, C., Vissac, A.M. & Meyer, D. (1996) Pathogenicity of IgA and/or IgM antibodies to heparin-PF4 complexes in patients with heparin-induced thrombocytopenia. British Journal of Haematology, 92, 954-959.
    • (1996) British Journal of Haematology , vol.92 , pp. 954-959
    • Amiral, J.1    Wolf, M.2    Fischer, A.M.3    Boyer-Neumann, C.4    Vissac, A.M.5    Meyer, D.6
  • 4
    • 0029918326 scopus 로고    scopus 로고
    • The pathogenesis of the antiphospholipid syndrome: A hypothesis based on parallelisms with heparin-induced thrombocytopenia
    • Arnout, J. (1996) The pathogenesis of the antiphospholipid syndrome: a hypothesis based on parallelisms with heparin-induced thrombocytopenia. Thrombosis and Haemostasis, 75, 536-541.
    • (1996) Thrombosis and Haemostasis , vol.75 , pp. 536-541
    • Arnout, J.1
  • 6
    • 0031239845 scopus 로고    scopus 로고
    • Activation of platelets by sera containing IgG1 heparin-dependent antibodies: An explanation for the predominance of the Fc gamma RIIa 'low responder' (his (131)) gene in patients with heparin-induced thrombocytopenia
    • Denomme, G.A., Warkentin, T.E., Horsewood, P., Sheppard, J.A.I., Warner, M.N. & Kelton, J.G. (1997) Activation of platelets by sera containing IgG1 heparin-dependent antibodies: an explanation for the predominance of the Fc gamma RIIa 'low responder' (his (131)) gene in patients with heparin-induced thrombocytopenia. Journal of Laboratory and Clinical Medicine, 130, 278-284.
    • (1997) Journal of Laboratory and Clinical Medicine , vol.130 , pp. 278-284
    • Denomme, G.A.1    Warkentin, T.E.2    Horsewood, P.3    Sheppard, J.A.I.4    Warner, M.N.5    Kelton, J.G.6
  • 7
    • 0029086769 scopus 로고
    • Characterization of the structural requirements for a carbohydrate based anticoagulant with a reduced risk of inducing the immunological type of heparin-associated thrombocytopenia
    • Greinacher, A., Alban, S., Dummel, V., Franz, G. & Mueller-Eckhardt, C. (1995) Characterization of the structural requirements for a carbohydrate based anticoagulant with a reduced risk of inducing the immunological type of heparin-associated thrombocytopenia. Thrombosis and Haemostasis, 74, 886-892.
    • (1995) Thrombosis and Haemostasis , vol.74 , pp. 886-892
    • Greinacher, A.1    Alban, S.2    Dummel, V.3    Franz, G.4    Mueller-Eckhardt, C.5
  • 8
    • 0028014541 scopus 로고
    • Heparin-associated thrombocytopenia: Isolation of the antibody and characterization of a multimolecular PF4-heparin complex as the major antigen
    • Greinacher, A., Potzsch, B., Amiral, J., Dummel, V., Eichner, A. & Mueller-Eckhardt, C. (1994) Heparin-associated thrombocytopenia: isolation of the antibody and characterization of a multimolecular PF4-heparin complex as the major antigen. Thrombosis and Haemostasis, 71, 247-251.
    • (1994) Thrombosis and Haemostasis , vol.71 , pp. 247-251
    • Greinacher, A.1    Potzsch, B.2    Amiral, J.3    Dummel, V.4    Eichner, A.5    Mueller-Eckhardt, C.6
  • 10
    • 0028243705 scopus 로고
    • Immunoglobulin G from patients with heparin-induced thrombocytopenia binds to a complex of heparin and platelet factor 4
    • Kelton, J., Smith, J., Warkentin, T., Hayward, C., Denomme, G. & Horsewood, P. (1994) Immunoglobulin G from patients with heparin-induced thrombocytopenia binds to a complex of heparin and platelet factor 4. Blood, 83, 3232-3239.
    • (1994) Blood , vol.83 , pp. 3232-3239
    • Kelton, J.1    Smith, J.2    Warkentin, T.3    Hayward, C.4    Denomme, G.5    Horsewood, P.6
  • 11
    • 0025241790 scopus 로고
    • Biologic and biochemic properties of recombinant platelet factor 4 demonstrate identity with the native protein
    • Park, K.S., Rifat, S., Eck, H., Adachi, K., Surrey, S. & Poncz, M. (1990) Biologic and biochemic properties of recombinant platelet factor 4 demonstrate identity with the native protein. Blood, 75, 1290-1295.
    • (1990) Blood , vol.75 , pp. 1290-1295
    • Park, K.S.1    Rifat, S.2    Eck, H.3    Adachi, K.4    Surrey, S.5    Poncz, M.6
  • 12
    • 0030703541 scopus 로고    scopus 로고
    • Differences in specificity of heparin-dependent antibodies developed in heparin-induced thrombocytopenia and consequences on cross-reactivity with danaparoid sodium
    • Pouplard, C., Amiral, J., Borg, J.Y., Vissac, A.M., Delahousse, B. & Gruel, Y. (1997) Differences in specificity of heparin-dependent antibodies developed in heparin-induced thrombocytopenia and consequences on cross-reactivity with danaparoid sodium. British Journal of Haematology, 99, 273-280.
    • (1997) British Journal of Haematology , vol.99 , pp. 273-280
    • Pouplard, C.1    Amiral, J.2    Borg, J.Y.3    Vissac, A.M.4    Delahousse, B.5    Gruel, Y.6
  • 13
    • 0033580605 scopus 로고    scopus 로고
    • Antibodies to platelet factor 4-heparin after cardiopulmonary bypass in patients anticoagulated with unfractionated heparin or a low-molecular-weight heparin - Clinical implications for heparin-induced thrombocytopenia
    • Pouplard, C., May, M.A., Iochmann, S., Amiral, J., Vissac, A.M., Marchand, M. & Gruel, Y. (1999a) Antibodies to platelet factor 4-heparin after cardiopulmonary bypass in patients anticoagulated with unfractionated heparin or a low-molecular-weight heparin - clinical implications for heparin-induced thrombocytopenia. Circulation, 99, 2530-2536.
    • (1999) Circulation , vol.99 , pp. 2530-2536
    • Pouplard, C.1    May, M.A.2    Iochmann, S.3    Amiral, J.4    Vissac, A.M.5    Marchand, M.6    Gruel, Y.7
  • 14
    • 0032926268 scopus 로고    scopus 로고
    • Decision analysis for use of platelet aggregation test, carbon 14 serotonin release assay, and heparin-platelet factor 4 enzyme-linked immunosorbent assay for diagnosis of heparin-induced thrombocytopenia
    • Pouplard, C., Amiral, J., Borg, J.Y., Laporte-Simitsidis, S., Delahousse, B. & Gruel, Y. (1999b) Decision analysis for use of platelet aggregation test, carbon 14 serotonin release assay, and heparin-platelet factor 4 enzyme-linked immunosorbent assay for diagnosis of heparin-induced thrombocytopenia. American Journal of Clinical Pathology, 111, 700-706.
    • (1999) American Journal of Clinical Pathology , vol.111 , pp. 700-706
    • Pouplard, C.1    Amiral, J.2    Borg, J.Y.3    Laporte-Simitsidis, S.4    Delahousse, B.5    Gruel, Y.6
  • 15
    • 0022640930 scopus 로고
    • A diagnostic test for heparin-induced thrombocytopenia
    • Sheridan, D., Carter, C. & Kelton, J. (1986) A diagnostic test for heparin-induced thrombocytopenia. Blood, 67, 27-30.
    • (1986) Blood , vol.67 , pp. 27-30
    • Sheridan, D.1    Carter, C.2    Kelton, J.3
  • 16
    • 0032006889 scopus 로고    scopus 로고
    • Antibodies from patients with heparin-induced thrombocytopenia/thrombosis recognize different epitopes on heparin: Platelet factor 4
    • Suh, J.S., Aster, R.H. & Visentin, G.P. (1998) Antibodies from patients with heparin-induced thrombocytopenia/thrombosis recognize different epitopes on heparin: platelet factor 4. Blood, 91, 916-922.
    • (1998) Blood , vol.91 , pp. 916-922
    • Suh, J.S.1    Aster, R.H.2    Visentin, G.P.3
  • 18
    • 0032723867 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: Molecular pathogenesis
    • Visentin, G. (1999) Heparin-induced thrombocytopenia: molecular pathogenesis. Thrombosis and Haemostasis, 82, 448-456.
    • (1999) Thrombosis and Haemostasis , vol.82 , pp. 448-456
    • Visentin, G.1
  • 19
    • 0028009642 scopus 로고
    • Antibodies from patients with heparin-induced thrombocytopenia/thrombosis are specific for platelet factor 4 complexed with heparin or bound to endothelial cells
    • Visentin, G., Ford, S., Scott, J. & Aster, R. (1994) Antibodies from patients with heparin-induced thrombocytopenia/thrombosis are specific for platelet factor 4 complexed with heparin or bound to endothelial cells. Journal of Clinical Investigation, 93, 81-88.
    • (1994) Journal of Clinical Investigation , vol.93 , pp. 81-88
    • Visentin, G.1    Ford, S.2    Scott, J.3    Aster, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.