Airway hyperresponsiveness to mannitol and methacholine and exhaled nitric oxide: A random-sample population study

Journal of Allergy and Clinical Immunology

Volumn 126, Issue 5, 2010, Pages 952-958

  Sverrild, Asger ^a   Porsbjerg, Celeste ^a   Thomsen, Simon Francis ^a   Backer, Vibeke ^a  

^a BISPEBJERG HOSPITAL   (Denmark)

Author keywords

Airway hyperresponsiveness; Asthma; Diagnosis; Epidemiology; Exhaled nitric oxide; Inflammation; Mannitol; Methacholine; Population

Indexed keywords

MANNITOL; METHACHOLINE; NITRIC OXIDE;

AIRWAY; ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; CONTROLLED STUDY; DENMARK; FEMALE; HUMAN; INFLAMMATION; MALE; POPULATION RESEARCH; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY;

ADOLESCENT; AREA UNDER CURVE; ASTHMA; BRONCHIAL HYPERREACTIVITY; BRONCHIAL PROVOCATION TESTS; BRONCHOCONSTRICTOR AGENTS; CROSS-SECTIONAL STUDIES; EXHALATION; FEMALE; HUMANS; MALE; MANNITOL; METHACHOLINE CHLORIDE; NITRIC OXIDE; ROC CURVE; SENSITIVITY AND SPECIFICITY; YOUNG ADULT;

EID: 78049463959     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2010.08.028     Document Type: Article

References (31)

1. R.O. Crapo, R. Casaburi, A.L. Coates, P.L. Enright, J.L. Hankinson, and C.G. Irvin Guidelines for methacholine and exercise challenge testing-1999 Am J Respir Crit Care Med 161 2000 309 329
2. V. Backer, S. Groth, A. Dirksen, N. Bach-Mortensen, K.K. Hansen, and E.M. Laursen Sensitivity and specificity of the histamine challenge test for the diagnosis of asthma in an unselected sample of children and adolescents Eur Respir J 4 1991 1093 1100
3. A.H. Henriksen, T. Lingaas-Holmen, M. Sue-Chu, and L. Bjermer Combined use of exhaled nitric oxide and airway hyperresponsiveness in characterizing asthma in a large population survey Eur Respir J 15 2000 849 855
4. D.W. Cockcroft, and B.E. Davis Diagnostic and therapeutic value of airway challenges in asthma Curr Allergy Asthma Rep 9 2009 247 253
5. M. Van Den Berge, R.J. Meijer, H.A. Kerstjens, D.M. de Reus, G.H. Koeter, and H.F. Kauffman PC(20) adenosine 5′-monophosphate is more closely associated with airway inflammation in asthma than PC(20) methacholine Am J Respir Crit Care Med 163 2001 1546 1550
6. S.D. Anderson, J. Brannan, J. Spring, N. Spalding, L.T. Rodwell, and K. Chan A new method for bronchial-provocation testing in asthmatic subjects using a dry powder of mannitol Am J Respir Crit Care Med 156 1997 758 765
7. C. Porsbjerg, J.D. Brannan, S.D. Anderson, and V. Backer Relationship between airway responsiveness to mannitol and to methacholine and markers of airway inflammation, peak flow variability and quality of life in asthma patients Clin Exp Allergy 38 2008 43 50
8. A. Sverrild, C. Porsbjerg, S.F. Thomsen, and V. Backer Diagnostic properties of inhaled mannitol in the diagnosis of asthma: a population study J Allergy Clin Immunol 124 2009 928 932 e1
9. J.A. Winder, K. Nash, and J.W. Brunn Validation of a life quality (LQ) test for asthma Ann Allergy Asthma Immunol 85 2000 467 472
10. E.B. Gade, S.F. Thomsen, C. Porsbjerg, and V. Backer The bronchial response to mannitol is attenuated by a previous methacholine test: but not vice versa Clin Exp Allergy 39 2009 966 971
11. R.O. Crapo, R. Casaburi, A.L. Coates, P.L. Enright, J.L. Hankinson, and C.G. Irvin Guidelines for methacholine and exercise challenge testing-1999. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, July 1999 Am J Respir Crit Care Med 161 2000 309 329
12. M.R. Miller, J. Hankinson, V. Brusasco, F. Burgos, R. Casaburi, and A. Coates Standardisation of spirometry Eur Respir J 26 2005 319 338
13. K. Yan, C. Salome, and A.J. Woolcock Rapid method for measurement of bronchial responsiveness Thorax 38 1983 760 765
14. ATS workshop proceedings: exhaled nitric oxide and nitric oxide oxidative metabolism in exhaled breath condensate: executive summary Am J Respir Crit Care Med 173 2006 811 813
15. D.E. Shaw, M.A. Berry, M. Thomas, R.H. Green, C.E. Brightling, and A.J. Wardlaw The use of exhaled nitric oxide to guide asthma management: a randomized controlled trial Am J Respir Crit Care Med 176 2007 231 237
16. M.A. Berry, D.E. Shaw, R.H. Green, C.E. Brightling, A.J. Wardlaw, and I.D. Pavord The use of exhaled nitric oxide concentration to identify eosinophilic airway inflammation: an observational study in adults with asthma Clin Exp Allergy 35 2005 1175 1179
17. S. Dreborg Skin tests used in type I allergy testing Allergy 44 suppl 10 1989 22 30
18. R. Pellegrino, G. Viegi, V. Brusasco, R.O. Crapo, F. Burgos, and R. Casaburi Interpretative strategies for lung function tests Eur Respir J 26 2005 948 968
19. C. Porsbjerg, L. Rasmussen, S.F. Thomsen, J.D. Brannan, S.D. Anderson, and V. Backer Response to mannitol in asymptomatic subjects with airway hyperresponsiveness to methacholine Clin Exp Allergy 37 2007 22 28
20. D.J. Hewitt Interpretation of the "positive" methacholine challenge Am J Ind Med 51 2008 769 781
21. L.M. van Den Toorn, J.B. Prins, S.E. Overbeek, H.C. Hoogsteden, and J.C. de Jongste Adolescents in clinical remission of atopic asthma have elevated exhaled nitric oxide levels and bronchial hyperresponsiveness Am J Respir Crit Care Med 162 2000 953 957
22. S.D. Anderson, B. Charlton, J.M. Weiler, S. Nichols, S.L. Spector, and D.S. Pearlman Comparison of mannitol and methacholine to predict exercise-induced bronchoconstriction and a clinical diagnosis of asthma Respir Res 10 2009 4
23. A. James, and G. Ryan Testing airway hyperresponsiveness using inhaled methacholine or histamine Respirology 2 1997 97 105
24. D.W. Cockcroft, and B.E. Davis The bronchoprotective effect of inhaling methacholine by using total lung capacity inspirations has a marked influence on the interpretation of the test results J Allergy Clin Immunol 17 2006 1244 1248
25. G.M. Moller, S.E. Overbeek, C.G. van Helden-Meeuwsen, H.C. Hoogsteden, and J.M. Bogaard Eosinophils in the bronchial mucosa in relation to methacholine dose-response curves in atopic asthma J Appl Physiol 86 1999 1352 1356
26. C. Porsbjerg, T.K. Lund, L. Pedersen, and V. Backer Inflammatory subtypes in asthma are related to airway hyperresponsiveness to mannitol and exhaled NO J Asthma 46 2009 606 612
27. J.D. Brannan, M. Gulliksson, S.D. Anderson, N. Chew, and M. Kumlin Evidence of mast cell activation and leukotriene release after mannitol inhalation Eur Respir J 22 2003 491 496
28. A.D. Smith, J.O. Cowan, K.P. Brassett, S. Filsell, C. McLachlan, and G. Monti-Sheehan Exhaled nitric oxide: a predictor of steroid response Am J Respir Crit Care Med 172 2005 453 459
29. J.D. Brannan, H. Koskela, S.D. Anderson, and H.K. Chan Budesonide reduces sensitivity and reactivity to inhaled mannitol in asthmatic subjects Respirology 7 2002 37 44
30. H. Koskela, L. Hyvärinen, J.D. Brannan, H.-K. Chan, and S.D. Anderson Sensitivity and validity of three bronchial provocation tests to demonstrate the effect of inhaled corticosteroids in asthma Chest 124 2003 1341 1349
31. J.D. Leuppi, C.M. Salome, C.R. Jenkins, S.D. Anderson, W. Xuan, and G.B. Marks Predictive markers of asthma exacerbations during stepwise dose-reduction of inhaled corticosteroids Am J Respir Crit Care Med 163 2001 406 412