A new method for bronchial-provocation testing in asthmatic subjects using a dry powder of mannitol

American Journal of Respiratory and Critical Care Medicine

Volumn 156, Issue 3 I, 1997, Pages 758-765

  Anderson, Sandra D ^b   Brannan, John ^c   Spring, Joanne ^c   Spalding, Natasha ^c   Rodwell, Leanne T ^c   Chan, Kim ^a   Gonda, Igor ^a   Walsh, Andrew ^a   Clark, Andrew R ^a  

^a GENENTECH INC   (United States)

^b ROYAL PRINCE ALFRED HOSPITAL   (Australia)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

MANNITOL; METHACHOLINE;

ADULT; ARTERIAL OXYGEN TENSION; ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC VALUE; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; INHALATIONAL DRUG ADMINISTRATION; MALE; PRIORITY JOURNAL; PROVOCATION TEST;

EID: 0030783036     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.156.3.9701113     Document Type: Article

References (35)

1. Sterk, P. J., L. M. Fabbri, Ph. H. Quanjer, D. W. Cockcroft, P. M. O'Byrne, S. D. Anderson, E. F. Juniper, and J.-L. Malo. 1993. Airway responsiveness: standardized challenge testing with pharmacological, physical and sensitizing stimuli in adults. Eur. Respir. J. 6(Suppl. 16):53-83.
2. Haby, M. M., J. K. Peat, C. M. Mellis, S. D. Anderson, and A. J. Woolcock. 1995. An exercise challenge for epidemiological studies of childhood asthma: validity and repeatability. Eur. Respir. J. 8:729-736.
3. Scott, G. C., and S. R. Braun. 1991. A survey of the current use and methods of analysis of bronchial provocational challenges. Chest 100:322-328.
4. Anderson, S. D., L. T. Rodwell, J. Du Toit, and I. H. Young. 1991. Duration of protection of inhaled salmeterol in exercise-induced asthma. Chest 100:1254-1260.
5. Eliasson, A. H., Y. Y. Phillips, and K. R. Rajagopal. 1992. Sensitivity and specificity of bronchial provocation testing: an evaluation of four techniques in exercise-induced bronchospasm. Chest 102:347-355.
6. Juniper, E. F., P. A. Kline, M. A. Vanzieleghem, E. H. Ramsdale, P. M. O'Byrne, and F. Hargreave. 1990. Effect of long-term treatment with inhaled corticosteroids on airway hyperresponsiveness and clinical asthma in non-steroid dependent asthmatics. Am. Rev. Respir. Dis. 142:832-836.
7. Toelle, B. G., J. K. Peat, C. M. Salome, C. M. Mellis, and A. J. Woolcock. 1992. Toward a definition of asthma for epidemiology. Am. Rev. Respir. Dis. 146:633-637.
8. Schoeffel, R. E., S. D. Anderson, and R. E. Altounyan. 1981. Bronchial hyperreactivity in response to inhalation of ultrasonically nebulised solutions of distilled water and saline. B.M.J. 283:1285-1287.
9. Eschenbacher, W. L., H. A. Boushey, and D. Sheppard. 1984. Alteration in osmolarity of inhaled aerosols cause bronchoconstriction and cough, but absence of a permanent anion causes cough alone. Am. Rev. Respir. Dis. 129:211-215.
10. Smith, C. M., and S. D. Anderson. 1989. Inhalation provocation tests using non-isotonic aerosols. J. Allergy Clin. Immunol. 84:781-790.
11. Rodwell, L. T., S. D. Anderson, J. du Toit, and J. P. Scale. 1993. Nedocromil sodium inhibits the airway response to hyperosmolar challenge in patients with asthma. Am. Rev. Respir. Dis. 146:1149-1155.
12. Riedler, J., T. Reade, M. Dalton, D. Holst, and C. F. Robertson. 1994. Hypertonic saline challenge in an epidemiological survey of asthma in children. Am. J. Respir. Crit. Care Med. 150:1632-1639.
13. Anderson, S. D., C. M. Smith, L. T. Rodwell, J. I. du Toit, J. Riedler, and C. F. Robertson. 1995. The use of non-isotonic aerosols for evaluating bronchial hyperresponsiveness. In S. Spector, editor. Provocation Challenge Procedures. Marcel Dekker, New York. 249-278.
14. Boulet, L.-P., H. Turcotte, and S. Tennina. 1989. Comparative efficacy of salbutamol, ipratropium and cromoglycate in the prevention of bronchospasm induced by exercise and hyperosmolar challenges. J. Allergy Clin. Immunol. 83:882-887.
15. Rodwell, L. T., S. D. Anderson, and J. P. Seale. 1992. Inhaled steroids modify bronchial responses to hyperosmolar saline. Eur. Respir. J. 5: 953-962.
16. Anderson, S. D., J. I. du Toit, L. T. Rodwell, and C. R. Jenkins. 1994. The acute effect of sodium cromoglycate on airway narrowing induced by 4.5% saline in asthmatic patients, before and during treatment with aerosol corticosteroids. Chest 105:673-680.
17. Anderson, S. D., and C. M. Smith. 1991. Osmotic challenges in the assessment of bronchial hyperresponsiveness. Am. Rev. Respir. Dis. 143: S43-S46.
18. Finnerty, J. P., C. Wilmont, and S. T. Holgate. 1989. Inhibition of hypertonic saline-induced bronchoconstriction by terfenadine and flurbiprofen: evidence for the predominant role of histamine. Am. Rev. Respir. Dis. 140:593-597.
19. Finney, M. J. B., S. D. Anderson, and J. L. Black. 1990. Terfenadine modifies airway narrowing induced by the inhalation of non-isotonic aerosols in subjects with asthma. Am. Rev. Respir. Dis. 141:1151-1157.
20. Rodwell, L. T., S. D. Anderson, and J. P. Seale. 1991. Inhaled clemastine inhibits airway narrowing caused by aerosols of non-isotonic saline. Eur. Respir. J. 4:1126-1134.
21. Eggleston, P. A., A. Kagey-Sobotka, and L. M. Lichtenstein. 1987. A comparison of the osmotic activation of basophils and human lung mast cells. Am. Rev. Respir. Dis. 135:1043-1048.
22. Pedersen, S., and G. Steffersen. 1986. Fenoterol powder inhaler technique in children: influence of inspiratory flow rate and breatholding. Eur. J. Respir. Dis. 68:207-214.
23. Fahy, D., B. Meakin, G. Ganderton, and A. B. Millar. 1993. Do changes in peak inspiratory flow occur with inspiration through dry powder inhalers? Thorax 48:460.
24. Vidgren, M. T., A. Karkkainen, P. Karjalainen, P. Paronen, and J. Nuutinen. 1988. Effect of powder inhaler design on drug deposition in the respiratory tract. Int. J. Pharm. 41:211-216.
25. Quanjer, Ph. H., G. J. Tammeling, J. E. Cotes, O. F. Pederson, R. Pelsin, and J.-C. Yernault. 1993. Lung volumes and forced ventilatory flows. Eur. Respir. J. 6(Suppl. 16):5-40.
26. Yan, K., C. Salome, and A. J. Woolcock. 1983. Rapid method for measurement of bronchial responsiveness. Thorax 38:760-765.
27. Peat, J. K., W. R. Unger, and D. Combe. 1994. Measuring changes in logarithmic data, with special reference to bronchial responsiveness. J. Clin. Epidemiol. 47:1099-1108.
28. Peat, J. K., C. M. Salome, G. Berry, and A. J. Woolcock. 1992. Relation of dose-response slope to respiratory symptoms and lung function in a population study of adults living in Busselton. Western Australia. Am. Rev. Respir. Dis. 146:860-865.
29. Bland, J. M., and D. G. Altman. 1986. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1: 307-310.
30. Chinn, S., J. R. Britton, P. G. J. Burney, A. E. Tattersfield, and A. O. Papacosta. 1987. Estimation and repeatability of the response to inhaled histamine in a community survey. Thorax 42:45-52.
31. Peat, J. K., C. M. Salome, A. Bauman, B. G. Toelle, S. L. Wachinger, and A. J. Woolcock. 1991. Repeatability of histamine bronchial challenge and comparability with methacholine bronchial challenge in a population of Australian schoolchildren Am. Rev. Respir. Dis. 144:338-343.
32. Riedler, J., T. Reade, and C. F. Robertson. 1994. Repeatability of the response to 4.5% NaCl challenge in children with mild to severe asthma. Pediatr. Pulmonol. 18:330-336.
33. Anderson, S. D., I. Gonda, J. F. Spring, B. Moore, N. Spalding, L. T. Rodwell, H. K. Chan, C. Hsu, A. Walsh, and A. R. Clark. 1996. A novel bronchial powder provocation test (BPT) using a dry respirable powder of sodium chloride (abstract). Am. J. Respir. Crit. Care Med. 153:A621.
34. Smith, C. M., and S. D. Anderson. 1989. Inhalational challenge using hypertonic saline in asthmatic subjects: a comparison with responses to hyperpnoea, methacholine, and water. Eur. Respir. J. 3:144-151.
35. Handbook of Pharmaceutical Excipients. 1986. American Pharmaceutical Association, Washington DC. 177-180.