Hypoxic preconditioning failure in aging hippocampal neurons: Impaired gene expression and rescue with intracellular calcium chelation

Journal of Neuroscience Research

Volumn 88, Issue 16, 2010, Pages 3520-3529

  Bickler, Philip E ^a   Fahlman, Christian S ^a   Gray, Jonathan J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Aging; Hippocampus; Hypoxia; Ischemia; Ischemic tolerance

Indexed keywords

1,2 BIS(2 AMINOPHENOXY)ETHANE N,N,N',N' TETRAACETIC ACID TETRAKIS(ACETOXYMETHYL ESTER); CALCIUM; CALCIUM CHELATING AGENT; HEAT SHOCK PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN BCL 2; PROTEIN C JUN; PROTEIN KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG;

AGED; ANIMAL CELL; ARTICLE; BRAIN SLICE; CALCIUM CELL LEVEL; CELL AGING; CELL CULTURE; CELL DEATH; CELL SURVIVAL; CHELATION; CONTROLLED STUDY; GENE EXPRESSION; HIPPOCAMPUS; HYPOXIC PRECONDITIONING; IN VITRO STUDY; ISCHEMIC PRECONDITIONING; NERVE CELL; NEUROPROTECTION; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

AGING; ANIMALS; CALCIUM; CALCIUM SIGNALING; CELL SURVIVAL; GENE EXPRESSION REGULATION; HIPPOCAMPUS; HYPOXIA, BRAIN; ISCHEMIC PRECONDITIONING; MICROARRAY ANALYSIS; NEURONS; ORGAN CULTURE TECHNIQUES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RNA; SIGNAL TRANSDUCTION;

EID: 78049415812     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22508     Document Type: Article

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