Endogenous mechanisms of neuroprotection

Epilepsia

Volumn 48, Issue SUPPL. 8, 2007, Pages 72-73

  Simon, Roger ^a,b   Henshall, David ^a   Stoehr, Sabine ^a   Meller, Robert ^a  

^a Robert Stone Dow Laboratories   (United States)

^b LEGACY RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN INJURY; BRAIN ISCHEMIA; BRAIN NERVE CELL; CELL SURVIVAL; CONFERENCE PAPER; ELECTROENCEPHALOGRAM; EPILEPSY; GENE EXPRESSION REGULATION; GENE INDUCTION; GENE REPRESSION; GENETIC TRANSCRIPTION; HUMAN; ISCHEMIC PRECONDITIONING; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; SEIZURE;

ANIMALS; BRAIN; CELL DEATH; CELLS, CULTURED; DIZOCILPINE MALEATE; EPILEPSY; GENE EXPRESSION REGULATION; HIPPOCAMPUS; HUMANS; ISCHEMIC PRECONDITIONING; MICE; MICROARRAY ANALYSIS; NEURONAL PLASTICITY; PHENOTYPE;

EID: 35748956821     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2007.01356.x     Document Type: Conference Paper

References (12)

1. Chen J, Graham SH, Zhu RL, Simon RP 1996) Stress proteins and tolerance to focal cerebral ischemia. J Cereb Blood Flow Metab 16 : 566 577.
2. da Silva R, Lucchinetti E, Pasch T, Schaub MC, Zaugg M 2004) Ischemic but not pharmacological preconditioning elicits a gene expression profile similar to unprotected myocardium. Physiol Genomics 20 : 117 130.
3. Dirnagl U, Simon RP, Hallenbeck JM 2003) Ischemic tolerance and endogenous neuroprotection. Trends Neurosci 26 : 248 254.
4. Furshpan EJ, Potter DD 1989) Seizure-like activity and cellular damage in rat hippocampal neurons in cell culture. Neuron 3 : 199 207.
5. Gidday JM 2006) Cerebral preconditioning and ischaemic tolerance. Nat Rev Neurosci 7 : 437 448.
6. Meller R, Schindler CK, Chu XP, Xiong ZG, Cameron JA, Simon RP, Henshall DC 2003) Seizure-like activity leads to the release of BAD from 14-3-3 protein and cell death in hippocampal neurons in vitro. Cell Death Differ 10 : 539 547.
7. Plamondon H, Blondeau N, Heurteaux C, Lazdunski M 1999) Mutually protective actions of kainic acid epileptic preconditioning and sublethal global ischemia on hippocampal neuronal death: involvement of adenosine A1 receptors and K(ATP) channels. J Cereb Blood Flow Metab 19 : 1296 1308.
8. Sasahira M, Lowry T, Simon RP, Greenberg DA 1995) Epileptic tolerance: prior seizures protect against seizure-induced neuronal injury. Neurol Lett 185 (2 95 98.
9. Sergeev P, da Silva R, Lucchinetti E, Zaugg K, Pasch T, Schaub MC, Zaugg M 2004) Trigger-dependent gene expression profiles in cardiac preconditioning: evidence for distinct genetic programs in ischemic and anesthetic preconditioning. Anesthesiology 100 : 474 488.
10. Stenzel-Poore MP, Stevens SL, Xiong Z, Lessov NS, Harrington CA, Mori M, Meller R, Rosenzweig HL, Tobar E, Shaw TE, Chu X, Simon RP 2003) Effect of ischaemic preconditioning on genomic response to cerebral ischaemia; similarity to neuroprotective strategies in hibernation and hypoxia-tolerant states. Lancet 362 (9389 1028 1037.
11. Stenzel-Poore M, Stevens SL, King JS, Simon RP 2007) Preconditioning reprograms the response to ischemic injury and primes the emergence of unique endogenous neurprotectie phentoypes: a speculative synthesis. Stroke 38 (2 Suppl 680 685.
12. Weih M, Kallenberg K, Bergk A, Dirnagl U, Harms L, Wernecke KD, Einhaupl KM 1999) Attenuated stroke severity after prodromal TIA: a role for ischemic tolerance in the brain? Stroke 30 : 1851 1854.