Molecular scaffolds with high propensity to form multi-target activity cliffs

Journal of Chemical Information and Modeling

Volumn 50, Issue 4, 2010, Pages 500-510

  Hu, Ye ^a   Bajorath, Jürgen ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BINDERS; LANDFORMS;

CHEMICAL COMPLEXITY; MOLECULAR SCAFFOLDS; MULTI-TARGETS; MULTIPLE TARGETS; STRUCTURE ACTIVITY RELATIONSHIPS;

SCAFFOLDS;

ARTICLE; CHEMICAL STRUCTURE; CONFORMATION; DRUG DEVELOPMENT; FACTUAL DATABASE; HUMAN; METHODOLOGY; STRUCTURE ACTIVITY RELATION;

DATABASES, FACTUAL; DRUG DISCOVERY; HUMANS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77952000491     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci100059q     Document Type: Article

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