-
1
-
-
0023821516
-
Identifcation of a putative regulator of early T cell activation genes
-
Shaw, J.P. et al. Identifcation of a putative regulator of early T cell activation genes. Science 241, 202-205 (1988).
-
(1988)
Science
, vol.241
, pp. 202-205
-
-
Shaw, J.P.1
-
2
-
-
0031451194
-
Tcn1p/Crz1p, a calcineurin-dependent transcription factor that differentially regulates gene expression in Saccharomyces cerevisiae
-
Matheos, D.P., Kingsbury, T.J., Ahsan, U.S. & Cunningham, K.W. Tcn1p/Crz1p, a calcineurin-dependent transcription factor that differentially regulates gene expression in Saccharomyces cerevisiae. Genes Dev. 11, 3445-3458 (1997).
-
(1997)
Genes Dev.
, vol.11
, pp. 3445-3458
-
-
Matheos, D.P.1
Kingsbury, T.J.2
Ahsan, U.S.3
Cunningham, K.W.4
-
3
-
-
0031438164
-
Calcineurin acts through the CRZ1/TCN1-encoded transcription factor to regulate gene expression in yeast
-
Stathopoulos, A.M. & Cyert, M.S. Calcineurin acts through the CRZ1/TCN1-encoded transcription factor to regulate gene expression in yeast. Genes Dev. 11, 3432-3444 (1997).
-
(1997)
Genes Dev.
, vol.11
, pp. 3432-3444
-
-
Stathopoulos, A.M.1
Cyert, M.S.2
-
4
-
-
0035479991
-
NFAT signaling in vertebrate development
-
Graef, I.A., Chen, F. & Crabtree, G.R. NFAT signaling in vertebrate development. Curr. Opin. Genet. Dev. 11, 505-512 (2001).
-
(2001)
Curr. Opin. Genet. Dev.
, vol.11
, pp. 505-512
-
-
Graef, I.A.1
Chen, F.2
Crabtree, G.R.3
-
5
-
-
0030070466
-
Regulation of PHO4 nuclear localization by the PHO80-PHO85 cyclin-CDK complex
-
O'Neill, E.M., Kaffman, A., Jolly, E.R. & O′Shea, E.K. Regulation of PHO4 nuclear localization by the PHO80-PHO85 cyclin-CDK complex. Science 271, 209-212 (1996).
-
(1996)
Science
, vol.271
, pp. 209-212
-
-
O'Neill, E.M.1
Kaffman, A.2
Jolly, E.R.3
O'Shea, E.K.4
-
6
-
-
0029943273
-
Visualization of glucocorticoid receptor translocation and intranuclear organization in living cells with a green fuorescent protein chimera
-
Htun, H., Barsony, J., Renyi, I., Gould, D.L. & Hager, G.L. Visualization of glucocorticoid receptor translocation and intranuclear organization in living cells with a green fuorescent protein chimera. Proc. Natl Acad. Sci. USA 93, 4845-4850 (1996).
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 4845-4850
-
-
Htun, H.1
Barsony, J.2
Renyi, I.3
Gould, D.L.4
Hager, G.L.5
-
7
-
-
50249142225
-
Analysis of the yeast kinome reveals a network of regulated protein localization during flamentous growth
-
Bharucha, N. et al. Analysis of the yeast kinome reveals a network of regulated protein localization during flamentous growth. Mol. Biol. Cell 19, 2708-2717 (2008).
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 2708-2717
-
-
Bharucha, N.1
-
8
-
-
0027756895
-
Controlling signal transduction with synthetic ligands
-
Spencer, D.M., Wandless, T.J., Schreiber, S.L. & Crabtree, G. Controlling signal transduction with synthetic ligands. Science 262, 1019-1024 (1993).
-
(1993)
Science
, vol.262
, pp. 1019-1024
-
-
Spencer, D.M.1
Wandless, T.J.2
Schreiber, S.L.3
Crabtree, G.4
-
9
-
-
0030013607
-
Controlling protein association and subcellular localization with a synthetic ligand that induces heterodimerization of proteins
-
Belshaw, P.J., Ho, S.N., Crabtree, G.R. & Schreiber, S.L. Controlling protein association and subcellular localization with a synthetic ligand that induces heterodimerization of proteins. Proc. Natl Acad. Sci. USA 93, 4604-4607 (1996).
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 4604-4607
-
-
Belshaw, P.J.1
Ho, S.N.2
Crabtree, G.R.3
Schreiber, S.L.4
-
10
-
-
0030878873
-
Inducible gene expression and protein translocation using nontoxic ligands identifed by a mammalian three-hybrid screen
-
Liberles, S.D., Diver, S.T., Austin, D.J. & Schreiber, S.L. Inducible gene expression and protein translocation using nontoxic ligands identifed by a mammalian three-hybrid screen. Proc. Natl Acad. Sci. USA 94, 7825-7830 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 7825-7830
-
-
Liberles, S.D.1
Diver, S.T.2
Austin, D.J.3
Schreiber, S.L.4
-
11
-
-
0024472603
-
A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase
-
Harding, W.M., Galat, A., Uehling, D.E. & Schreiber, S.L. A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase. Nature 341, 758-760 (1989).
-
(1989)
Nature
, vol.341
, pp. 758-760
-
-
Harding, W.M.1
Galat, A.2
Uehling, D.E.3
Schreiber, S.L.4
-
12
-
-
0025647885
-
Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin
-
Bierer, B.E. et al. Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin. Proc. Natl Acad. Sci. USA 87, 9231-9235 (1990).
-
(1990)
Proc. Natl Acad. Sci. USA
, vol.87
, pp. 9231-9235
-
-
Bierer, B.E.1
-
13
-
-
0028360374
-
A mammalian protein targeted by G1-arresting rapamycin-receptor complex
-
Brown, E.J. et al. A mammalian protein targeted by G1-arresting rapamycin-receptor complex. Nature 369, 756-758 (1994).
-
(1994)
Nature
, vol.369
, pp. 756-758
-
-
Brown, E.J.1
-
14
-
-
0028239893
-
RAFT1: A mammalian protein that binds FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs
-
Sabatini, D.M., Erdjument-Bromage, H., Lui, M., Tempst, P. & Snyder, S.H. RAFT1: a mammalian protein that binds FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs. Cell 78, 35-43 (1994).
-
(1994)
Cell
, vol.78
, pp. 35-43
-
-
Sabatini, D.M.1
Erdjument-Bromage, H.2
Lui, M.3
Tempst, P.4
Snyder, S.H.5
-
15
-
-
36048962201
-
Chemical control over protein-protein interactions: Beyond inhibitors
-
Gestwicki, J.E. & Marinec, P.S. Chemical Control Over Protein-Protein Interactions: Beyond Inhibitors. Comb. Chem. High Throughput Screen 10, 667-675 (2007).
-
(2007)
Comb. Chem. High Throughput Screen
, vol.10
, pp. 667-675
-
-
Gestwicki, J.E.1
Marinec, P.S.2
-
16
-
-
0024358184
-
Identifcation and characterization of a nuclear localization sequence-binding protein in yeast
-
Lee, W.-C. & Melese, T. Identifcation and characterization of a nuclear localization sequence-binding protein in yeast. Proc. Natl Acad. Sci. USA 86, 8808-8812 (1989).
-
(1989)
Proc. Natl Acad. Sci. USA
, vol.86
, pp. 8808-8812
-
-
Lee, W.-C.1
Melese, T.2
-
17
-
-
0024616796
-
Context affects nuclear protein localization in Saccharomyces cerevisiae
-
Nelson, M. & Silver, P. Context affects nuclear protein localization in Saccharomyces cerevisiae. Mol. Cell. Biol. 9, 384-389 (1989).
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 384-389
-
-
Nelson, M.1
Silver, P.2
-
18
-
-
0029745374
-
An RNA-export mediator with an essential nuclear export signal
-
Murphy, R. & Wente, S.R. An RNA-export mediator with an essential nuclear export signal. Nature 383, 357-360 (1996).
-
(1996)
Nature
, vol.383
, pp. 357-360
-
-
Murphy, R.1
Wente, S.R.2
-
19
-
-
50849105776
-
A small molecule-directed approach to control protein localization and function
-
Geda, P. et al. A small molecule-directed approach to control protein localization and function. Yeast 25, 577-594 (2008).
-
(2008)
Yeast
, vol.25
, pp. 577-594
-
-
Geda, P.1
-
20
-
-
67650493437
-
Conditional nuclear import and export of yeast proteins using a chemical inducer of dimerization
-
Patury, S., Geda, P., Dobry, C.J., Kumar, A. & Gestwicki, J.E. Conditional nuclear import and export of yeast proteins using a chemical inducer of dimerization. Cell Biochem. Biophys. (2009).
-
(2009)
Cell Biochem. Biophys.
-
-
Patury, S.1
Geda, P.2
Dobry, C.J.3
Kumar, A.4
Gestwicki, J.E.5
-
21
-
-
0033515037
-
Affnity modulation of small-molecule ligands by borrowing endogenous protein surfaces
-
Briesewitz, R., Ray, G.T., Wandless, T.J. & Crabtree, G.R. Affnity modulation of small-molecule ligands by borrowing endogenous protein surfaces. Proc. Natl Acad. Sci. USA 96, 1953-1958 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 1953-1958
-
-
Briesewitz, R.1
Ray, G.T.2
Wandless, T.J.3
Crabtree, G.R.4
-
22
-
-
0028845027
-
A general strategy for producing conditional alleles of Src-like tyrosine kinases
-
Spencer, D.M., Graef, I., Austin, D.J., Schreiber, S.L. & Crabtree, G. A general strategy for producing conditional alleles of Src-like tyrosine kinases. Proc. Natl Acad. Sci. USA 92, 9805-9809 (1995).
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 9805-9809
-
-
Spencer, D.M.1
Graef, I.2
Austin, D.J.3
Schreiber, S.L.4
Crabtree, G.5
-
23
-
-
0031239961
-
Rapid targeting of nuclear proteins to the cytoplasm
-
Klemm, J.D., Beals, C.R. & Crabtree, G.R. Rapid targeting of nuclear proteins to the cytoplasm. Curr. Biol. 7, 638-644 (1997).
-
(1997)
Curr. Biol.
, vol.7
, pp. 638-644
-
-
Klemm, J.D.1
Beals, C.R.2
Crabtree, G.R.3
-
24
-
-
0346156074
-
Conditional protein alleles using knockin mice and a chemical inducer of dimerization
-
Stankunas, K. et al. Conditional protein alleles using knockin mice and a chemical inducer of dimerization. Mol. Cell 12, 1615-1624 (2003).
-
(2003)
Mol. Cell
, vol.12
, pp. 1615-1624
-
-
Stankunas, K.1
-
25
-
-
33847405867
-
Chemical rescue of cleft palate and midline defects in conditional GSK-3beta mice
-
Liu, K.J., Arron, J.R., Stankunas, K., Crabtree, G.R. & Longaker, M.T. Chemical rescue of cleft palate and midline defects in conditional GSK-3beta mice. Nature 446, 79-82 (2007).
-
(2007)
Nature
, vol.446
, pp. 79-82
-
-
Liu, K.J.1
Arron, J.R.2
Stankunas, K.3
Crabtree, G.R.4
Longaker, M.T.5
-
26
-
-
77649268470
-
Organelle-specifc, rapid induction of molecular activities and membrane tethering
-
Komatsu, T. et al. Organelle-specifc, rapid induction of molecular activities and membrane tethering. Nat. Methods 7, 206-208.
-
Nat. Methods
, vol.7
, pp. 206-208
-
-
Komatsu, T.1
-
27
-
-
52049084405
-
The anchor-away technique: Rapid, conditional establishment of yeast mutant phenotypes
-
Haruki, H., Nishikawa, J. & Laemmli, U.K. The anchor-away technique: rapid, conditional establishment of yeast mutant phenotypes. Mol. Cell 31, 925-932 (2008).
-
(2008)
Mol. Cell
, vol.31
, pp. 925-932
-
-
Haruki, H.1
Nishikawa, J.2
Laemmli, U.K.3
-
28
-
-
68549090921
-
Quantifcation of nuclear protein transport using induced heterodimerization
-
Busch, A., Kiel, T. & Hubner, S. Quantifcation of nuclear protein transport using induced heterodimerization. Traffc 10, 1221-1227 (2009).
-
(2009)
Traffc
, vol.10
, pp. 1221-1227
-
-
Busch, A.1
Kiel, T.2
Hubner, S.3
-
29
-
-
84908087547
-
New mutant phenotype data curation system in the Saccharomyces Genome Database
-
2009
-
Costanzo, M.C. et al. New mutant phenotype data curation system in the Saccharomyces Genome Database. Database (Oxford) 2009, bap001 (2009).
-
(2009)
Database (Oxford)
-
-
Costanzo, M.C.1
-
30
-
-
0024442393
-
A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin
-
Siekierka, J.J., Hung, S.H.Y., Poe, M., Lin, C.S. & Sigal, N.H. A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin. Nature 341, 755-757 (1989).
-
(1989)
Nature
, vol.341
, pp. 755-757
-
-
Siekierka, J.J.1
Hung, S.H.Y.2
Poe, M.3
Lin, C.S.4
Sigal, N.H.5
-
31
-
-
0028137771
-
TOR1 and TOR2 are structurally and functionally similar but not identical phosphatidylinositol kinase homologues in yeast
-
Helliwell, S.B. et al. TOR1 and TOR2 are structurally and functionally similar but not identical phosphatidylinositol kinase homologues in yeast. Mol. Biol. Cell 5, 105-118 (1994).
-
(1994)
Mol. Biol. Cell
, vol.5
, pp. 105-118
-
-
Helliwell, S.B.1
-
32
-
-
0028825698
-
TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin
-
Lorenz, M.C. & Heitman, J. TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin. J. Biol. Chem. 270, 27531-27537 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 27531-27537
-
-
Lorenz, M.C.1
Heitman, J.2
-
33
-
-
0028561918
-
Interaction between FKBP12-rapamycin and TOR involves a conserved serine residue
-
Stan, R. et al. Interaction between FKBP12-rapamycin and TOR involves a conserved serine residue. J. Biol. Chem. 269, 32027-32030 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 32027-32030
-
-
Stan, R.1
-
34
-
-
30744467675
-
Rapamycin analogs with differential binding specifcity permit orthogonal control of protein activity
-
Bayle, J.H. et al. Rapamycin analogs with differential binding specifcity permit orthogonal control of protein activity. Chem. Biol. 13, 99-107 (2006).
-
(2006)
Chem. Biol.
, vol.13
, pp. 99-107
-
-
Bayle, J.H.1
-
35
-
-
34547602770
-
Rescue of degradation-prone mutants of the FK506-rapamycin binding (FRB) protein with chemical ligands
-
Stankunas, K. et al. Rescue of degradation-prone mutants of the FK506-rapamycin binding (FRB) protein with chemical ligands. Chembiochem 8, 1162-1169 (2007).
-
(2007)
Chembiochem
, vol.8
, pp. 1162-1169
-
-
Stankunas, K.1
-
36
-
-
0036138908
-
A variant of yellow fuorescent protein with fast and effcient maturation for cell-biological applications
-
Nagai, T. et al. A variant of yellow fuorescent protein with fast and effcient maturation for cell-biological applications. Nat. Biotechnol. 20, 87-90 (2002).
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 87-90
-
-
Nagai, T.1
-
37
-
-
0020529962
-
Transformation of intact yeast cells treated with alkali cations
-
Ito, H., Fukuda, Y., Murata, K. & Kimura, A. Transformation of intact yeast cells treated with alkali cations. J. Bacteriol. 153, 163-168 (1983).
-
(1983)
J. Bacteriol.
, vol.153
, pp. 163-168
-
-
Ito, H.1
Fukuda, Y.2
Murata, K.3
Kimura, A.4
-
38
-
-
0037087575
-
Subcellular localization of the yeast proteome
-
Kumar, A. et al. Subcellular localization of the yeast proteome. Genes Dev. 16, 707-719 (2002).
-
(2002)
Genes Dev.
, vol.16
, pp. 707-719
-
-
Kumar, A.1
-
39
-
-
77952020349
-
A profle of differentially abundant proteins at the yeast cell periphery during pseudohyphal growth
-
Xu, T. et al. A profle of differentially abundant proteins at the yeast cell periphery during pseudohyphal growth. J. Biol. Chem. 285, 15476-15488.
-
J. Biol. Chem.
, vol.285
, pp. 15476-15488
-
-
Xu, T.1
-
40
-
-
0029329592
-
Structure-activity studies of rapamycin analogs: Evidence that the C-7 methoxy group is part of the effector domain and positioned at the FKBP12-FRAP interface
-
Luengo, J.I. et al. Structure-activity studies of rapamycin analogs: evidence that the C-7 methoxy group is part of the effector domain and positioned at the FKBP12-FRAP interface. Chem. Biol. 2, 471-481 (1995).
-
(1995)
Chem. Biol.
, vol.2
, pp. 471-481
-
-
Luengo, J.I.1
-
41
-
-
0000444566
-
Kinetics of the reactions of allylsilanes, allylgermanes, and allylstannanes with carbenium ions
-
Hagen, G. & Mayr, H. Kinetics of the reactions of allylsilanes, allylgermanes, and allylstannanes with carbenium ions. J. Am. Chem. Soc. 113, 4954-4961 (1991).
-
(1991)
J. Am. Chem. Soc.
, vol.113
, pp. 4954-4961
-
-
Hagen, G.1
Mayr, H.2
-
42
-
-
38749144782
-
Large-scale analysis of yeast flamentous growth by systematic gene disruption and overexpression
-
Jin, R., Dobry, C.J., McCown, P.J. & Kumar, A. Large-scale analysis of yeast flamentous growth by systematic gene disruption and overexpression. Mol. Biol. Cell 19, 284-296 (2008).
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 284-296
-
-
Jin, R.1
Dobry, C.J.2
McCown, P.J.3
Kumar, A.4
-
43
-
-
40549143977
-
Multipurpose transposon-insertion libraries for large-scale analysis of gene function in yeast
-
Kumar, A. Multipurpose transposon-insertion libraries for large-scale analysis of gene function in yeast. Methods Mol. Biol. 416, 117-129 (2008).
-
(2008)
Methods Mol. Biol.
, vol.416
, pp. 117-129
-
-
Kumar, A.1
-
44
-
-
0032873415
-
Three new dominant drug resistance cassettes for gene disruption in Saccharomyces cerevisiae
-
Goldstein, A.L. & McCusker, J.H. Three new dominant drug resistance cassettes for gene disruption in Saccharomyces cerevisiae. Yeast 15, 1541-1553 (1999).
-
(1999)
Yeast
, vol.15
, pp. 1541-1553
-
-
Goldstein, A.L.1
McCusker, J.H.2
-
45
-
-
27744587302
-
Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex
-
Keogh, M.C. et al. Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex. Cell 123, 593-605 (2005).
-
(2005)
Cell
, vol.123
, pp. 593-605
-
-
Keogh, M.C.1
|