Aspergillus fumigatus allergen expression is coordinately regulated in response to hydrogen peroxide and cyclic AMP

Clinical and Molecular Allergy

Volumn 8, Issue , 2010, Pages

  Fraczek, Marcin G ^a,b   Rashid, Rifat ^a,b   Denson, Marian ^a,b   Denning, David W ^a,b   Bowyer, Paul ^a,b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ASCARIS ANTIGEN; BETA TUBULIN; CYCLIC AMP; HYDROGEN PEROXIDE; LIPID; MINERAL OIL;

ANOXIA; ANTIGEN EXPRESSION; ARTICLE; ASPERGILLUS FUMIGATUS; CONTROLLED STUDY; FUNGAL CELL CULTURE; FUNGAL GENETICS; FUNGAL STRAIN; FUNGUS GROWTH; GENE EXPRESSION; HEAT SHOCK; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; IMMUNE RESPONSE; MACROPHAGE; NONHUMAN; NORMAL HUMAN; OUTCOME ASSESSMENT; OXIDATIVE STRESS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 78049347983     PISSN: None     EISSN: 14767961     Source Type: Journal    
DOI: 10.1186/1476-7961-8-15     Document Type: Article

References (43)

1. (ISAAC) The International Survey of Asthma and Allergy in Childhood Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis and atopic eczema. Lancet 1998, 351:1225-1232. 10.1016/S0140-6736(97)07302-9, 9643741, (ISAAC) The International Survey of Asthma and Allergy in Childhood.
2. Dietert RR, Zelikoff JT. Early-life environment, developmental immunotoxicology, and the risk of pediatric allergic disease including asthma. Birth Defects Res B Dev Reprod Toxicol 2008, 83:547-60. 10.1002/bdrb.20170, 19085948.
3. Frieri M. Advances in the understanding of allergic asthma. Allergy Asthma Proc 2007, 28:614-9. 10.2500/aap.2007.28.2952, 18201423.
4. Aalberse R. Structural biology of allergens. J Allergy Clin Immunol 2000, 106:228-38. 10.1067/mai.2000.110226, 10932064.
5. Aalberse RC, Akkerdaas J, van Ree R. Cross-reactivity of IgE antibodies to allergens. Allergy 2001, 56:478-90. 10.1034/j.1398-9995.2001.056006478.x, 11421891.
6. Vijay HM, Kurup VP. Fungal allergens. Clin Allergy Immunol 2008, 21:141-60.
7. Green BJ, Tovey ER, Sercombe JK, Blachere FM, Beezhold DH, Schmechel D. Airborne fungal fragments and allergenicity. Med Mycol 2006, 44(Suppl 1):S245-55. 10.1080/13693780600776308, 17050446.
8. Gershwin LJ. Effects of allergenic extracts on airway epithelium. Curr Allergy Asthma Rep 2007, 7:357-62. 10.1007/s11882-007-0054-7, 17697644.
9. Reed CE. Inflammatory effect of environmental proteases on airway mucosa. Curr Allergy Asthma Rep 2007, 7:368-74. 10.1007/s11882-007-0056-5, 17697646.
10. Simon-Nobbe B, Denk U, Pöll V, Rid R, Breitenbach M. The spectrum of fungal allergy. Int Arch Allergy Immunol 2008, 145:58-86. 10.1159/000107578, 17709917.
11. Woodfolk JA. Allergy and dermatophytes. Clin Microbiol Rev 2005, 18:30-43. 10.1128/CMR.18.1.30-43.2005, 544172, 15653817.
12. Saubolle MA. Fungal pneumonias. Semin Respir Infect 2000, 15:162-77. 10.1053/srin.2000.9598, 10983933.
13. Hickman-Davis JM, Fang FC, Nathan C, Shepherd VL, Voelker DR, Wright JR. Lung surfactant and reactive oxygen-nitrogen species: antimicrobial activity and host-pathogen interactions. Am J Physiol Lung Cell Mol Physiol 2001, 281:L517-23.
14. Wright JR. Pulmonary surfactant: a front line of lung host defense. J Clin Invest 2003, 111:1453-5. 155177, 12750392.
15. Kobayashi H. Airway biofilms: implications for pathogenesis and therapy of respiratory tract infections. Treat Respir Med 2005, 4:241-53. 10.2165/00151829-200504040-00003, 16086598.
16. Segal BH. Role of macrophages in host defense against aspergillosis and strategies for immune augmentation. Oncologist 2007, 12(Suppl 2):7-13.
17. Zmeili OS, Soubani AO. Pulmonary aspergillosis: a clinical update. Qjm 2007, 100:317-34. 10.1093/qjmed/hcm035, 17525130.
18. Dagenais TR, Keller NP. Pathogenesis of Aspergillus fumigatus in Invasive Aspergillosis. Clin Microbiol Rev 2009, 22:447-65. 10.1128/CMR.00055-08, 2708386, 19597008.
19. Hope WW. Invasion of the alveolar-capillary barrier by Aspergillus spp.: therapeutic and diagnostic implications for immunocompromised patients with invasive pulmonary aspergillosis.". Med Mycol 2009, 47(Suppl 1):S291-8. 10.1080/13693780802510232, 19306226.
20. Slavin RG, Hutcheson PS, Chauhan B, Bellone CJ. An overview of allergic bronchopulmonary aspergillosis with some new insights. Allergy Asthma Proc 2004, 25:395-9.
21. Denning DW, O'Driscoll BR, Hogaboam CM, Bowyer P, Niven RM. The link between fungi and severe asthma: a summary of the evidence. Eur Respir J 2006, 27:615-26. 10.1183/09031936.06.00074705, 16507864.
22. Denning DW, O'Driscoll BR, Powell G, Chew F, Atherton GT, Vyas A, Miles J, Morris J, Niven RM. Randomized controlled trial of oral antifungal treatment for severe asthma with fungal sensitization: The Fungal Asthma Sensitization Trial (FAST) study. Am J Respir Crit Care Med 2009, 179:11-8. 10.1164/rccm.200805-737OC, 18948425.
23. O'Driscoll BR, Powell G, Chew F, Niven RM, Miles JF, Vyas A, Denning DW. Comparison of skin prick tests with specific serum immunoglobulin E in the diagnosis of fungal sensitization in patients with severe asthma. Clin Exp Allergy 2009, 39:1677-83. 10.1111/j.1365-2222.2009.03339.x, 19689458.
24. Bowyer P, Fraczek M, Denning DW. Comparative genomics of fungal allergens and epitopes shows widespread distribution of closely related allergen and epitope orthologues. BMC Genomics 2006, 7:251. 10.1186/1471-2164-7-251, 1613252, 17029625.
25. Bowyer P, Denning DW. Genomic analysis of allergen genes in Aspergillus spp: the relevance of genomics to everyday research. Med Mycol 2007, 45:17-26. 10.1080/13693780600972907, 17325940.
26. Nierman WC, Pain A, Anderson MJ, Wortman JR, Kim HS, Arroyo J, Berriman M, et al. Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus. Nature 2005, 438:1151-6. 10.1038/nature04332, 16372009.
27. Freitas JS, Silva EM, Rossi A. Identification of nutrient-dependent changes in extracellular pH and acid phosphatase secretion in Aspergillus nidulans. Genet Mol Res 2007, 6:721-9.
28. Latge JP. The pathobiology of Aspergillus fumigatus. Trends Microbiol 2001, 9:382-389. 10.1016/S0966-842X(01)02104-7, 11514221.
29. Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 2001, 29:e45. 10.1093/nar/29.9.e45, 55695, 11328886.
30. Toledano MB, Delaunay A, Biteau B, Spector D, Azevedo D. Oxidative stress responses in yeast. Yeast Stress Responses 2003, 305-387. Springer-Verlag, Hohman MW, Berlin S.
31. Ibrahim-Granet O, Philippe B, Boleti H, Boisvieux-Ulrich E, Grenet D, Stern M, Latgé JP. Phagocytosis and intracellular fate of Aspergillus fumigatus conidia inalveolar macrophages. Infection and Immunity 2003, 71:891-903. 10.1128/IAI.71.2.891-903.2003, 145364, 12540571.
32. Philippe B, Ibrahim-Granet O, Prévost MC, Gougerot-Pocidalo MA, Sanchez Perez M, Van der Meeren A, Latgé JP. Killing of Aspergillus fumigatus by alveolar macrophages is mediated by reactive oxidant intermediates. Infection and Immunity 2003, 71:3034-3042. 10.1128/IAI.71.6.3034-3042.2003, 155721, 12761080.
33. Schwede F, Maronde E, Genieser H, Jastorff B. Cyclic nucleotide analogs as biochemical tools and prospective drugs. Pharmacol Ther 2000, 87:199-226. 10.1016/S0163-7258(00)00051-6, 11008001.
34. Hope WW, Walsh TJ, Denning DW. Laboratory diagnosis of invasive aspergillosis. Lancet Infect Dis 2005, 5:609-622. 10.1016/S1473-3099(05)70238-3, 16183515.
35. Latge JP. Aspergillus fumigatus and aspergillosis. Clin Microbiol Rev 1999, 12:310-350. 88920, 10194462.
36. Forman HJ, Torres M. Reactive oxygen species and cell signaling: respiratory burst in macrophage signalling. Am J Respir Crit Care Med 2002, 166:4-8.
37. Asif AR, Oellerich M, Amstrong VW, Riemenschneider B, Monod M, Reichard U. Proteome of conidial surface associated proteins of Aspergillus fumigatus reflecting potential vaccine candidates and allergens. J Proteome Res 2006, 5:954-962. 10.1021/pr0504586, 16602703.
38. Harcus D, Nantel A, Marcil A, Rigby T, Whiteway M. Transcription profiling of cyclic AMP signaling in Candida albicans. Mol Biol Cell 2004, 15:4490-4499. 10.1091/mbc.E04-02-0144, 519143, 15269278.
39. Wan H, Winton HL, Soeller C, Stewart GA, Thompson PJ, Gruenert DC, Cannell MB, Garrod DR, Robinson C. Tight junction properties of the immortalized human bronchial epithelial cell lines Calu-3 and 16HBE14o-. Eur Respir J 2000, 15:1058-68. 10.1034/j.1399-3003.2000.01514.x, 10885425.
40. Thornton DJ, Rousseau K, McGuckin MA. Structure and function of the polymeric mucins in airways mucus. Annu Rev Physiol 2008, 70:459-486. 10.1146/annurev.physiol.70.113006.100702, 17850213.
41. Sugui JA, Kim HS, Zarember KA, Chang YC, Gallin JI, Nierman WC, Kwon-Chung KJ. Genes differentially expressed in conidia and hyphae of Aspergillus fumigatus upon exposure to human neutrophils. PLoS One 2008, 3:e2655. 10.1371/journal.pone.0002655, 2481287, 18648542.
42. Lessing F, Kniemeyer O, Wozniok I, Loeffler J, Kurzai O, Haertl A, Brakhage A. The Aspergillus fumigatus transcriptional regulator AfYap1 represents the major regulator for defense against reactive oxygen intermediates but is dispensable for pathogenicity in an intranasal mouse infection model. Eukaryot Cell 2007, 6(12):2290-302. 10.1128/EC.00267-07, 2168236, 17921349.
43. McDonagh A, Fedorova ND, Crabtree J, Yu Y, Kim S, Chen D, Loss O, Cairns T, Goldman G, Armstrong-James D, Haynes K, Haas H, Schrettl M, May G, Nierman WC, Bignell E. Sub-telomere directed gene expression during initiation of invasive aspergillosis. PLoS Pathog 2008, 4(9):e1000154. 10.1371/journal.ppat.1000154, 2526178, 18787699.