Genomic analysis of allergen genes in Aspergillus spp.: The relevance of genomics to everyday research

Medical Mycology

Volumn 45, Issue 1, 2007, Pages 17-26

  Bowyer, Paul ^a   Denning, David W ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; ASPARTIC ACID; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 88; HEAT SHOCK PROTEIN 90; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; ASPERGILLUS; ASPERGILLUS FUMIGATUS; CONTROLLED STUDY; CROSS REACTION; DNA SEQUENCE; FUNGAL GENETICS; FUNGAL STRAIN; GENOMICS; NOMENCLATURE; NONHUMAN; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; GENETICS; IMMUNOLOGY; ISOLATION AND PURIFICATION; METHODOLOGY; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; SEQUENCE ALIGNMENT;

ASPERGILLUS; ASPERGILLUS FUMIGATUS; FUNGI;

ALLERGENS; AMINO ACID SEQUENCE; ASPERGILLUS; BASE SEQUENCE; GENOMICS; MOLECULAR SEQUENCE DATA; SEQUENCE ALIGNMENT;

EID: 34249746426     PISSN: 13693786     EISSN: 14602709     Source Type: Journal    
DOI: 10.1080/13693780600972907     Document Type: Article

References (53)

1. (1998) Steering committee. Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis and atopic eczema. Lancet, 351, pp. 1225-1232.
2. (1996) Variations in the prevalence of respiratory symptoms, self-reported asthma attacks and the use of asthma medications in the European community respiratory health survey (ECRHS). Eur Respir J, 9, pp. 687-695.
3. Andersson, K. and Lidholm, J. (2003) Characteristics and immunobiology of grass pollen allergens. Int Arch Allergy Immunol, 130, pp. 87-107.
4. Aalberse, RC. (2000) Structural biology of allergens. J Allergy Clin Immunol, 106, pp. 228-238.
5. Edwards, MR, Collins, AM and Ward, RL. (2001) The application of phage display in allergy research: Characterization of IgE, identification of allergens and development of novel therapeutics. Curr Pharm Biotechnol, 2, pp. 225-240.
6. Crameri, R. (2001) High throughput screening: A rapid way to recombinant allergens. Allergy, 56, pp. 30-34.
7. Cromwell, O., Suck, R. and Kahlert, H. (2004) Transition of recombinant allergens from bench to clinical application. Methods, 32, pp. 300-312.
8. Wallner, M., Gruber, P. and Radauer, C. (2004) Lab scale and medium scale production of recombinant allergens in Escherichia coli. Methods, 32, pp. 219-226.
9. Wu, CH and Lee, MF. (2005) Molecular characteristics of cockroach allergens. Cell Mol Immunol, 2, pp. 177-180.
10. Valenta, R. (2002) The future of antigen-specific immunotherapy of allergy. Nat Rev Immunol, 2, pp. 446-453.
11. Dolen, WK. (2001) Skin testing and immunoassays for allergen-specific IgE. Clin Rev Allergy Immunol, 21, pp. 229-239.
12. Mothes, N., Valenta, R. and Spitzauer, S. (2006) Allergy testing: The role of recombinant allergens. Clin Chem Lab Med, 44, pp. 125-132.
13. Kazemi-Shirazi, L., Niederberger, V. and Linhart, B. (2002) Recombinant marker allergens: Diagnostic gatekeepers for the treatment of allergy. Int Arch Allergy Immunol, 127, pp. 259-268.
14. Valenta, R., Lidholm, J. and Niederberger, V. (1999) The recombinant allergen-based concept of component-resolved diagnostics and immunotherapy (CRD and CRIT). Clin Exp Allergy, 29, pp. 896-904.
15. Deinhofer, K., Sevcik, H. and Balic, N. (2004) Microarrayed allergens for IgE profiling. Methods, 32, pp. 249-254.
16. Jeong, KY, Hongb, CS and Yong, TS. (2006) Recombinant allergens for diagnosis and immunotherapy of allergic disorders,with emphasis on cockroach allergy. Curr Protein Pept Sci, 7, pp. 57-71.
17. Pons, L., Palmer, K. and Burks, W. (2005) Towards immunotherapy for peanut allergy. Curr Opin Allergy Clin Immunol, 5, pp. 558-562.
18. Pons, L. and Burks, W. (2005) Novel treatments for food allergy. Expert Opin Investig Drugs, 14, pp. 829-834.
19. Sampson, HA. (2004) Update on food allergy. J Allergy Clin Immunol, 113, pp. 805-819.
20. Romagnani, S. (2003) New therapeutic strategies in allergic diseases. Drugs Today (Barc), 39, pp. 849-865.
21. Nelson, HS. (2006) Advances in upper airway diseases and allergen immunotherapy. J Allergy Clin Immunol, 117, pp. 1047-1053.
22. Schmidt-Weber, CB and Blaser, K. (2006) Immunological mechanisms of specific allergen immunotherapy. Inflamm Allergy Drug Targets, 5, pp. 15-21.
23. Nelson, HS. (2006) Efficacy and safety of allergen immunotherapy in children. Ann Allergy Asthma Immunol, 96, p. S2.
24. Weber, RW. (2005) Cross-reactivity of pollen allergens: Recommendations for immunotherapy vaccines. Curr Opin Allergy Clin Immunol, 5, pp. 563-569.
25. Mari, A., Schneider, P., Wally, V., Breitenbach, M. and Simon-Nobbe, B. (2003) Sensitization to fungi: Epidemiology, comparative skin tests, and IgE reactivity of fungal extracts. Clin Exp Allergy, 33, pp. 1429-1438.
26. Denning, DW, O'Driscoll, BR, Hogaboam, CM, Bowyer, P. and Niven, RM. (2006) The link between fungi and severe asthma: A summary of the evidence. Eur Respir J, 27, pp. 615-626.
27. Ronning, CM, Fedorova, ND and Bowyer, P. (2005) Genomics of Aspergillus fumigatus. Rev Iberoam Micol, 22, pp. 223-228.
28. Kurup, VP. (2005) Aspergillus antigens: Which are important?. Med Mycol, 43, p. S189.
29. Rementeria, A., Lopez-Molina, N. and Ludwig, A. (2005) Genes and molecules involved in Aspergillus fumigatus virulence. Rev Iberoam Micol, 22, pp. 1-23.
30. Bille, J., Marchetti, O. and Calandra, T. (2005) Changing face of health-care associated fungal infections. Curr Opin Infect Dis, 18, pp. 314-319.
31. Moss, RB. (2005) Pathophysiology and immunology of allergic bronchopulmonary aspergillosis. Med Mycol, 43, p. S203.
32. Slavin, RG, Hutcheson, PS, Chauhan, B. and Bellone, CJ. (2004) An overview of allergic bronchopulmonary aspergillosis with some new insights. Allergy Asthma Proc, 25, pp. 395-399.
33. Calera, JA, Ovejero, MC and Lopez-Medrano, R. (1997) Characterization of the Aspergillus nidulans aspnd1 gene demonstrates that the ASPND1 antigen, which it encodes, and several Aspergillus fumigatus immunodominant antigens belong to the same family. Infect Immun, 65, pp. 1335-1344.
34. Nierman, WC, Pain, A. and Anderson, MJ (2005) Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus. Nature, 438, pp. 1151-1156.
35. Baker, D. and Sali, A. (2001) Protein structure prediction and structural genomics. Science, 294, pp. 93-96.
36. Mari, A. and Riccioli, D. (2004) The Allergome Website - A database of allergenic molecules. aim, structure, and data of a web-based resource. J Allergy Clin Immunol, 113, p. S301.
37. Fiers, MW, Kleter, GA and Nijland, H. (2004) Allermatch, a webtool for the prediction of potential allergenicity according to current FAO/WHO Codex alimentarius guidelines. BMC Bioinformatics, 5, p. 133.
38. Boeckmann, B., Bairoch, A. and Apweiler, R. (2003) The SWISS-PROT protein knowledgebase and its supplement TrEMBL in 2003. Nucleic Acids Res, 31, pp. 365-370.
39. Hileman, RE, Silvanovich, A. and Goodman, RE (2002) Bioinformatic methods for allergenicity assessment using a comprehensive allergen database. Int Arch Allergy Immunol, 128, pp. 280-291.
40. Altschul, SF, Madden, TL and Schäffer, AA (1997) Gapped BLAST and PSI-BLAST: A new generation of protein database search programs. Nucleic Acids Res, 25, pp. 3389-3402.
41. Kumar, A., Reddy, LV, Sochanik, A. and Kurup, VP. (1993) Isolation and characterization of a recombinant heat shock protein of Aspergillus fumigatus. J Allergy Clin Immunol, 91, pp. 1024-1030.
42. Kurup, VP and Banerjee, B. (2000) Fungal allergens and peptide epitopes Peptides, 21, pp. 589-599.
43. Denikus, N., Orfaniotou, F. and Wulf, G. (2005) Fungal antigens expressed during invasive aspergillosis. Infect Immun, 73, p. 4704.
44. Ramadan, G., Davies, B., Kurup, VP and Keever-Taylor, CA. (2005) Generation of cytotoxic T cell responses directed to human leucocyte antigen Class I restricted epitopes from the Aspergillus f16 allergen. Clin Exp Immunol, 140, pp. 81-91.
45. Ramadan, G., Davies, B., Kurup, VP and Keever-Taylor, CA. (2005) Generation of Th1 T cell responses directed to a HLA Class II restricted epitope from the Aspergillus f16 allergen. Clin Exp Immunol, 139, pp. 257-267.
46. Bozza, S., Gaziano, R. and Lipford, GB (2002) Vaccination of mice against invasive aspergillosis with recombinant Aspergillus proteins and CpG oligodeoxynucleotides as adjuvants. Microbes Infect, 4, pp. 1281-1290.
47. Banerjee, B., Kurup, VP, Greenberger, PA, Johnson, BD and Fink, JN. (2001) Cloning and expression of Aspergillus fumigatus allergen Asp f 16 mediating both humoral and cell-mediated immunity in allergic bronchopulmonary aspergillosis (ABPA). Clin Exp Allergy, 31, pp. 761-770.
48. Hemmann, S. (1998) Cloning, characterization and clinical evaluation of recombinant Aspergillus fumigatus allergens [PhD Thesis]. University of Zurich, University of Zurich, Zurich
49. Shankar, J., Gupta, PD and Sridhara, S. (2005) Immunobiochemical analysis of cross-reactive glutathione-S-transferase allergen from different fungal sources. Immunol Invest, 34, pp. 37-51.
50. Nigam, S., Ghosh, PC and Sarma, PU. (2003) A new glycoprotein allergen/ antigen with the protease activity from Aspergillus fumigatus. Int Arch Allergy Immunol, 132, pp. 124-131.
51. Toida, J., Kondoh, K., Fukuzawa, M., Ohnishi, K. and Sekiguchi, J. (1995) Purification and characterization of a lipase from Aspergillus oryzae. Biosci Biotechnol Biochem, 59, pp. 1199-1203.
52. Brant, A., Hole, A. and Cannon, J. (2004) Occupational asthma caused by cellulase and lipase in the detergent industry. Occup Environ Med, 61, pp. 793-795.
53. Rhyner, C., Weichel, M. and Fluckiger, S. (2004) Cloning allergens via phage display. Methods, 32, pp. 212-218.