Identification of nutrient-dependent changes in extracellular pH and acid phosphatase secretion in Aspergillus nidulans

Genetics and Molecular Research

Volumn 6, Issue 3, 2007, Pages 721-729

  Freitas, J S ^a   Silva, E M ^a   Rossi, A ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Acid phosphatase; Ambient pH; Aspergillus nidulans; Colonial growth; Enzyme secretion; palC gene

Indexed keywords

ACID PHOSPHATASE; BUFFER; PHOSPHATE; TROMETAMOL;

ACIDITY; ARTICLE; ASPERGILLUS NIDULANS; CONIDIUM; CULTURE MEDIUM; ENZYME ACTIVITY; ENZYME RELEASE; FUNGAL GENE; FUNGAL STRAIN; FUNGUS CULTURE; FUNGUS GROWTH; FUNGUS MUTANT; NONHUMAN; NUTRIENT; PALC4 GENE; PH; SIGNAL TRANSDUCTION;

ACID PHOSPHATASE; ASPERGILLUS NIDULANS; COLONY COUNT, MICROBIAL; FOOD; HYDROGEN-ION CONCENTRATION;

EMERICELLA NIDULANS;

EID: 36048940303     PISSN: None     EISSN: 16765680     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Anhê AC, Lima-Oliveira AP and Azeredo-Oliveira MT (2007). Acid phosphatase activity distribution in salivary glands of triatomines (Heteroptera, Reduviidae, Triatominae). Genet. Mol. Res. 6: 197-205.
2. Arst HN Jr, Bignell E and Tilburn J (1994). Two new genes involved in signalling ambient pH in Aspergillus nidulans. Mol. Gen. Genet. 245: 787-790.
3. Baek YU, Martin SJ and Davis DA (2006). Evidence for novel pH-dependent regulation of Candida albicans Rim101, a direct transcriptional repressor of the cell wall beta-glycosidase Phr2. Eukaryot. Cell 5: 1550-1559.
4. Caddick MX, Brownlee AG and Arst HN Jr (1986). Regulation of gene expression by pH of the growth medium in Aspergillus nidulans. Mol. Gen. Genet. 203: 346-353.
5. Clutterbuck AJ (1993). Aspergillus nidulans. In: Genetic maps. Locus maps of complex genomes (O'Brien SJ, ed.). Cold Spring Harbor Laboratory Press, New York, 3.71-3.84.
6. Cove DJ (1966). The induction and repression of nitrate reductase in the fungus Aspergillus nidulans. Biochim. Biophys. Acta 113: 51-56.
7. Díez E, Álvaro J, Espeso EA, Rainbow L, et al. (2002). Activation of the Aspergillus PacC zinc finger transcription factor requires two proteolytic steps. EMBO J. 21: 1350-1359.
8. Dorn G (1965a). Genetic analysis of the phosphatases in Aspergillus nidulans. Genet. Res. 10: 13-26.
9. Dorn G (1965b). Phosphatase mutants in Aspergillus nidulans. Science 150: 1183-1184.
10. Han SW, Nahas E and Rossi A (1987). Regulation of synthesis and secretion of acid and alkaline phosphatases in Neurospora crassa. Curr. Genet. 11: 521-527.
11. Hartree EF (1972). Determination of protein: a modification of the Lowry method that gives a linear photometric response. Anal. Biochem. 48: 422-427.
12. Heinonen JK and Lahti RJ (1981). A new and convenient colorimetric determination of inorganic orthophosphate and its application to the assay of inorganic pyrophosphatase. Anal. Biochem. 113: 313-317.
13. Li M, Martin SJ, Bruno VM, Mitchell AP, et al. (2004). Candida albicans Rim13p, a protease required for Rim101p processing at acidic and alkaline pHs. Eukaryot. Cell 3: 741-751.
14. Maccheroni W Jr, Pombeiro SRC, Martinez-Rossi NM and Rossi A (1991). pH and acid phosphatase determinations after growth of Aspergillus nidulans on solid medium. Fungal Genet. Newsl. 38: 78-79. (http://www.fgsc.net/ fgn38/maccheroni.pdf).
15. Maccheroni W Jr, Martinez-Rossi NM and Rossi A (1995). Does gene palB regulate the transcription or the post-translational modification of Pi-repressible phosphatases of Aspergillus nidulans? Braz. J. Med. Biol. Res. 28: 31-38.
16. Maccheroni W Jr, May GS, Martinez-Rossi NM and Rossi A (1997). The sequence of palF, an environmental pH response gene in Aspergillus nidulans. Gene 194: 163-167.
17. Maccheroni W Jr, May GS, Martinez-Rossi NM and Rossi A (2000). The levels of mRNA expressed by gene palF of A. nidulans do not appear to be pH regulated. Fungal Genet. Newsl. 47: 72-73. (http://www.fgsc.net/ fgn47/47Maccheroni.htm).
18. Martinez-Rossi NM, Nozawa SR, May GS, Ferreira-Nozawa MS, et al. (2002). Characterization of pacC-1, a wide domain regulatory gene responsive to ambient pH in Neurospora crassa. Fungal Genet. Newsl. 49: 4. Abstracts Neurospora 2002 Conference. (http://www.fgsc.net/asil2002/posterabs.htm).
19. McCluskey K (2003). The fungal genetics stock center: from molds to molecules. Adv. Appl. Microbiol. 52: 245-262.
20. Nahas E and Rossi A (1984). Properties of repressible alkaline phosphatase secreted by the wild type strain 74A of Neurospora crassa. Phytochemistry 23: 507-510.
21. Nahas E, Terenzi HF and Rossi A (1982). Effect of carbon source and pH on the production and secretion of acid phosphatase (EC 3.1.3.2) and alkaline phosphatase (EC 3.1.3.1) in Neurospora crassa. J. Genet. Microbiol. 128: 2017-2021.
22. Negrete-Urtasun S, Reiter W, Díez E, Denison SH, et al. (1999). Ambient pH signal transduction in Aspergillus: completion of gene characterization. Mol. Microbiol. 33: 994-1003.
23. Nozawa SR and Rossi A (2000). Gene pacA+ codes for the multiple active forms of Pi-repressible acid phosphatase in the Aspergillus nidulans. World J. Microbiol. Biotechnol. 16: 333-336.
24. Nozawa SR, May GS, Martinez-Rossi NM, Ferreira-Nozawa MS, et al. (2003a). Mutation in a calpain-like protease affects the posttranslational mannosylation of phosphatases in Aspergillus nidulans. Fungal Genet. Biol. 38: 220-227.
25. Nozawa SR, Ferreira-Nozawa MS, Martinez-Rossi NM and Rossi A (2003b). The pH-induced glycosylation of secreted phosphatases is mediated in Aspergillus nidulans by the regulatory gene pacC-dependent pathway. Fungal Genet. Biol. 39: 286-295. Addendum: Nozawa et al. (2003). Fungal Genet. Biol. 40: 287-288.
26. Orejas M, Espeso EA, Tilburn J, Sarkar S, et al. (1995). Activation of the Aspergillus PacC transcription factor in response to alkaline ambient pH requires proteolysis of the carboxy-terminal moiety. Genes Dev. 9: 1622-1632.
27. Payton M, McCullough W and Roberts CF (1976). Agar as a carbon source and its effect on the utilization of other carbon sources by acetate non-utilizing (acu) mutants of Aspergillus nidulans. J. Gen. Microbiol. 94: 228-233.
28. Peñalva MA and Arst HN Jr (2002). Regulation of gene expression by ambient pH in filamentous fungi and yeasts. Microbiol. Mol. Biol. Rev. 66: 426-446.
29. Peñas MM, Hervás-Aguilar A, Múnera-Huertas T, Reoyo E, et al. (2007). Further characterization of the signaling proteolysis step in the Aspergillus nidulans pH signal transduction pathway. Eukaryot. Cell 6: 960-970.
30. Pérez-Esteban B, Orejas M, Gomez-Pardo E and Peñalva MA (1993). Molecular characterization of a fungal secondary metabolism promoter: transcription of the Aspergillus nidulans isopenicillin N synthetase gene is modulated by upstream negative elements. Mol. Microbiol. 9: 881-895.
31. Rossi A and Arst HN Jr (1990). Mutants of Aspergillus nidulans able to grow at extremely acidic pH acidify the medium less than wild type when grown at more moderate pH. FEMS Microbiol. Lett. 54: 51-53.
32. Silva EM, Freitas JS, Gras DE, Leal J, et al. (2007). Identification of genes up regulated in the palA1 mutant strain of Aspergillus nidulans. Fungal Genet. Newsl. 54: 316-316. Abstracts 24th Fungal Genetics Conference. (http://www.fgsc.net/asil2007/xxivFGCposterAbs.htm).
33. Thedei G Jr and Rossi A (2006). Identification of non-specific alkaline phosphatases in hyphal cells of the fungus Neurospora crassa by in situ histochemistry. Genet. Mol. Res. 5: 483-486.
34. Thedei G Jr, Doubowetz TH and Rossi A (1994). Effect of carbon source and extracellular pH on the acidification of the culture medium and phosphatase excretion in Neurospora crassa. Braz. J. Med. Biol. Res. 27: 1129-1134.
35. Tilburn J, Sarkar S, Widdick DA, Espeso EA, et al. (1995). The Aspergillus PacC zinc finger transcription factor mediates regulation of both acid- and alkaline-expressed genes by ambient pH. EMBO J. 14: 779-790.
36. Tilburn J, Sánchez-Ferrero JC, Reoyo E, Arst HN Jr, et al. (2005). Mutational analysis of the pH signal transduction component PalC of Aspergillus nidulans supports distant similarity to BRO1 domain family members. Genetics 171: 393-401.