Investigation of toxicological effects of Shuanghuanglian injection in Beagle dogs by metabonomic and traditional approaches

Experimental Biology and Medicine

Volumn 235, Issue 11, 2010, Pages 1356-1364

  Yan, Guangyan ^a   Zhao, Yinglan ^a   Deng, Pengchi ^b   Lv, Lei ^a   Wang, Yanli ^c   Bu, Qian ^a   Liu, Bin ^a   Hu, Chunyan ^a   Zhuo, Yanqiang ^a   Yang, Xunning ^a   Wang, Li ^a   Cen, Xiaobo ^a,d  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

^c TIANJIN CHILDREN S HOSPITAL   (China)

^d High Tech Development District of Chengdu   (China)

Author keywords

Hemolysis; Metabonomic; Shuanghuanglian injection; Toxicity

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CHOLINE; CREATINE KINASE; CREATININE; FERRIC FERROCYANIDE; HEMOGLOBIN; HEMOSIDERIN; LACTIC ACID; PHOSPHORYLCHOLINE; SHUANGHUANGLIAN; TAURINE; TOXIC SUBSTANCE; UNCLASSIFIED DRUG;

ACANTHOCYTOSIS; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; BIOMICS; BLOOD ANALYSIS; BLOOD TOXICITY; CLINICAL CHEMISTRY; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; CREATININE BLOOD LEVEL; DOG; ERYTHROCYTE COUNT; ERYTHROCYTE VOLUME; FEMALE; HEMOGLOBIN DETERMINATION; HEMOLYSIS; HEMOLYTIC ANEMIA; HEMOSIDEROSIS; HISTOPATHOLOGY; KIDNEY; LACTATE BLOOD LEVEL; LIVER; MALE; MEAN CORPUSCULAR HEMOGLOBIN; METABONOMICS; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RETICULOCYTE COUNT; SPLEEN; TOXICITY TESTING; TOXICOKINETICS; TRANSMISSION ELECTRON MICROSCOPY; UREA NITROGEN BLOOD LEVEL;

ANEMIA, HEMOLYTIC; ANIMALS; BIOLOGICAL MARKERS; BODY WEIGHT; CHOLINE; DOGS; DRUGS, CHINESE HERBAL; INJECTIONS, INTRAVENOUS; KIDNEY; LACTIC ACID; LIVER; METABOLOMICS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; ORGAN SIZE; PHOSPHORYLCHOLINE; SERUM; SPLEEN; TAURINE;

ANIMALIA; CANIS FAMILIARIS;

EID: 78049321044     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1258/ebm.2010.009390     Document Type: Article

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