An Introduction to the Neurobiology of Bipolar Illness Onset, Recurrence and Progression

Bipolar Disorder: Clinical and Neurobiological Foundations

Volumn , Issue , 2010, Pages 96-109

  Post, Robert M ^a   Kauer Sant'Anna, Marcia ^b  

^a GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Childhood onset bipolar illness accelerated rate of illness stage evolution; Episode sensitization and stress sensitization replicated with few exceptions; Genetic mechanisms calcium channel (CACNA1C) and neurotransmitter release mechanism (ANK 3), vulnerability to bipolar illness; Increases in BDNF in dopaminergic pathway defeat stress and cocaine sensitization; Multiple reflections of illness progression idea of using medical staging models in BD; Neurobiology of bipolar illness onset, recurrence and progression; Neurobiology of bipolar illness, precisely delineated and understood; Normal processes of learning and memory and responses to environmental stressors, short and long term changes in gene expression; Pathophysiological mechanisms dichotomous, genetic inheritance or environmental alterations; Prefrontal cortical deficits and hypofunctions versus paralimbic hyperfunction

Indexed keywords

EID: 78049286075     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470661277.ch11     Document Type: Chapter

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