-
1
-
-
63349111371
-
Forum on: The role of recombinant factor VIII in children with severe haemophilia a
-
Franchini M, Coppola A, Molinari AC, et al. Forum on: the role of recombinant factor VIII in children with severe haemophilia A. Haemophilia 2009; 15: 578-86.
-
(2009)
Haemophilia
, vol.15
, pp. 578-586
-
-
Franchini, M.1
Coppola, A.2
Molinari, A.C.3
-
2
-
-
0035822038
-
The hemophilias - From royal genes to gene therapy
-
Mannucci PM, Tuddenham EG. The hemophilias - from royal genes to gene therapy. N Engl J Med 2001; 344: 1773-9.
-
(2001)
N Engl J Med
, vol.344
, pp. 1773-1779
-
-
Mannucci, P.M.1
Tuddenham, E.G.2
-
3
-
-
0024555758
-
Use of recombinant antihemophilic factor in the treatment of two patients with classic hemophilia
-
White GC 2nd, McMillan CW, Kingdon HS, Shoemaker CB. Use of recombinant antihemophilic factor in the treatment of two patients with classic hemophilia. N Engl J Med 1989; 320: 166-70.
-
(1989)
N Engl J Med
, vol.320
, pp. 166-170
-
-
White II, G.C.1
McMillan, C.W.2
Kingdon, H.S.3
Shoemaker, C.B.4
-
5
-
-
77954871125
-
Recombinant factor VIII concentrates
-
Franchini M, Lippi G. Recombinant factor VIII concentrates. Semin Thromb Hemost 2010; 36: 493-7.
-
(2010)
Semin Thromb Hemost
, vol.36
, pp. 493-497
-
-
Franchini, M.1
Lippi, G.2
-
6
-
-
77953549604
-
Mortality and causes of death in Italian persons with haemophilia, 1990-2007
-
Tagliaferri A, Rivolta GF, Iorio A, et al. Mortality and causes of death in Italian persons with haemophilia, 1990-2007. Haemophilia 2010; 16: 437-46.
-
(2010)
Haemophilia
, vol.16
, pp. 437-446
-
-
Tagliaferri, A.1
Rivolta, G.F.2
Iorio, A.3
-
7
-
-
33750995901
-
Prophylaxis in haemophilia patients with inhibitors
-
Leissinger CA. Prophylaxis in haemophilia patients with inhibitors. Haemophilia 2006; 12(Suppl 6): 67-73.
-
(2006)
Haemophilia
, vol.12
, Issue.SUPPL. 6
, pp. 67-73
-
-
Leissinger, C.A.1
-
8
-
-
44249093256
-
Back to the future: A recent history of haemophilia treatment
-
Mannucci PM. Back to the future: a recent history of haemophilia treatment. Haemophilia 2008; 14(Suppl 3): 10-8.
-
(2008)
Haemophilia
, vol.14
, Issue.SUPPL. 3
, pp. 10-18
-
-
Mannucci, P.M.1
-
9
-
-
1142273431
-
Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion
-
Llewelyn CA, Hewitt PE, Knight RS, et al. Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion. Lancet 2004; 363: 417-21.
-
(2004)
Lancet
, vol.363
, pp. 417-421
-
-
Llewelyn, C.A.1
Hewitt, P.E.2
Knight, R.S.3
-
10
-
-
43949134531
-
Recombinant clotting factors
-
Pipe SW. Recombinant clotting factors. Thromb Haemost 2008; 99: 840-50.
-
(2008)
Thromb Haemost
, vol.99
, pp. 840-850
-
-
Pipe, S.W.1
-
11
-
-
0141482007
-
Cost of care and quality of life for patients with hemophilia complicated by inhibitors: The COCIS study group
-
DOI 10.1182/blood-2003-03-0941
-
Gringeri A, Mantovani LG, Scalone L, Mannucci PM. Cost of care and quality of life for patients with hemophilia complicated by inhibitors: the COCIS Study Group. Blood 2003; 102: 2358-63. (Pubitemid 37193570)
-
(2003)
Blood
, vol.102
, Issue.7
, pp. 2358-2363
-
-
Gringeri, A.1
Mantovani, L.G.2
Scalone, L.3
Mannucci, P.M.4
-
12
-
-
33750704965
-
The need for previously untreated patient population studies in understanding the development of factor VIII inhibitors
-
Gomperts ED. The need for previously untreated patient population studies in understanding the development of factor VIII inhibitors. Haemophilia 2006; 12: 573-8.
-
(2006)
Haemophilia
, vol.12
, pp. 573-578
-
-
Gomperts, E.D.1
-
13
-
-
33646262886
-
Overview of inhibitors
-
Astermark J. Overview of inhibitors. Semin Hematol 2006; 43 (2 Suppl 4):S3-7.
-
(2006)
Semin Hematol
, vol.43
, Issue.2 SUPPL. 4
-
-
Astermark, J.1
-
14
-
-
0028285537
-
High titer inhibitors in severe haemophilia A. A meta-analysis based on eight long-term follow-up studies concerning inhibitors associated with crude or intermediate purity factor VIII products
-
Briet E, Rosendaal FR, Kreuz W, et al. High titer inhibitors in severe haemophilia A. A meta-analysis based on eight long-term follow-up studies concerning inhibitors associated with crude or intermediate purity factor VIII products. Thromb Haemost 1994; 72: 162-4.
-
(1994)
Thromb Haemost
, vol.72
, pp. 162-164
-
-
Briet, E.1
Rosendaal, F.R.2
Kreuz, W.3
-
15
-
-
76749138587
-
Assessing risk factors: Prevention of inhibitors in haemophilia
-
Chambost H. Assessing risk factors: prevention of inhibitors in haemophilia. Haemophilia 2010; 16(Suppl 2): 10-5.
-
(2010)
Haemophilia
, vol.16
, Issue.SUPPL. 2
, pp. 10-15
-
-
Chambost, H.1
-
16
-
-
33751010515
-
Recombinant vs. plasma-derived products, especially those with intact VWF, regarding inhibitor development
-
Ettingshausen CE, Kreuz W. Recombinant vs. plasma-derived products, especially those with intact VWF, regarding inhibitor development. Haemophilia 2006; 12(Suppl 6): 102-6.
-
(2006)
Haemophilia
, vol.12
, Issue.SUPPL. 6
, pp. 102-106
-
-
Ettingshausen, C.E.1
Kreuz, W.2
-
17
-
-
0042626369
-
The incidence of inhibitor development according to specific mutations -and treatment?
-
Goodeve A. The incidence of inhibitor development according to specific mutations -and treatment? Blood Coagul Fibrinolysis 2003; 14(Suppl 1): S17-21.
-
(2003)
Blood Coagul Fibrinolysis
, vol.14
, Issue.SUPPL. 1
-
-
Goodeve, A.1
-
18
-
-
33751017726
-
The epidemiology of factor VIII inhibitors
-
Hay CR. The epidemiology of factor VIII inhibitors. Haemophilia 2006; 12(Suppl 6): 23-9.
-
(2006)
Haemophilia
, vol.12
, Issue.SUPPL. 6
, pp. 23-29
-
-
Hay, C.R.1
-
19
-
-
33751014075
-
Genetic risk factors for inhibitors to factors VIII and IX
-
Oldenburg J, Pavlova A. Genetic risk factors for inhibitors to factors VIII and IX. Haemophilia 2006; 12(Suppl 6): 15-22.
-
(2006)
Haemophilia
, vol.12
, Issue.SUPPL. 6
, pp. 15-22
-
-
Oldenburg, J.1
Pavlova, A.2
-
20
-
-
0032787813
-
Incidence of inhibitors in haemophilia a patients - A review of recent studies of recombinant and plasma-derived factor VIII concentrates
-
DOI 10.1046/j.1365-2516.1999.00300.x
-
Scharrer I, Bray GL, Neutzling O. Incidence of inhibitors in haemophilia A patients - a review of recent studies of recombinant and plasma-derived factor VIII concentrates. Haemophilia 1999; 5: 145-54. (Pubitemid 29326763)
-
(1999)
Haemophilia
, vol.5
, Issue.3
, pp. 145-154
-
-
Scharrer, I.1
Bray, G.L.2
Neutzling, O.3
-
21
-
-
0027496218
-
Incidence of inhibitors in haemophiliacs. A review of the literature
-
Scharrer I, Neutzling O. Incidence of inhibitors in haemophiliacs. A review of the literature. Blood Coagul Fibrinolysis 1993; 4: 753-8.
-
(1993)
Blood Coagul Fibrinolysis
, vol.4
, pp. 753-758
-
-
Scharrer, I.1
Neutzling, O.2
-
22
-
-
0001961415
-
Experiences with recombinant factor VIII products: Development of inhibitors and immune tolerance therapy
-
Scharrer I, Neutzling O, Schwaab R, et al. Experiences with recombinant factor VIII products: development of inhibitors and immune tolerance therapy. Ann Hematol 1998; 76(Suppl 1): A1-6.
-
(1998)
Ann Hematol
, vol.76
, Issue.SUPPL. 1
-
-
Scharrer, I.1
Neutzling, O.2
Schwaab, R.3
-
23
-
-
78049310001
-
VWF-containing FVIII concentrates and inhibitors in hemophilia A: A critical literature review
-
Franchini M, Lippi G. VWF-containing FVIII concentrates and inhibitors in hemophilia A: a critical literature review. Thromb Haemost 2010.
-
(2010)
Thromb Haemost
-
-
Franchini, M.1
Lippi, G.2
-
24
-
-
34548358878
-
Methodological shortcomings in assessment of factor VIII concentrate inhibition
-
Verbruggen B, van Heerde W, Budde U. Methodological shortcomings in assessment of factor VIII concentrate inhibition. Haemophilia 2007; 13: 680-1.
-
(2007)
Haemophilia
, vol.13
, pp. 680-681
-
-
Verbruggen, B.1
Van Heerde, W.2
Budde, U.3
-
25
-
-
33846244931
-
VWF protects FVIII from endocytosis by dendritic cells and subsequent presentation to immune effectors
-
Dasgupta S, Repesse Y, Bayry J, et al. VWF protects FVIII from endocytosis by dendritic cells and subsequent presentation to immune effectors. Blood 2007; 109: 610-2.
-
(2007)
Blood
, vol.109
, pp. 610-612
-
-
Dasgupta, S.1
Repesse, Y.2
Bayry, J.3
-
26
-
-
33748586497
-
Recombinant factor VIII and factor VIII-von Willebrand factor complex do not present danger signals for human dendritic cells
-
Pfistershammer K, Stockl J, Siekmann J, et al. Recombinant factor VIII and factor VIII-von Willebrand factor complex do not present danger signals for human dendritic cells. Thromb Haemost 2006; 96: 309-16.
-
(2006)
Thromb Haemost
, vol.96
, pp. 309-316
-
-
Pfistershammer, K.1
Stockl, J.2
Siekmann, J.3
-
27
-
-
0036282373
-
Inhibitor development in previously untreated patients with hemophilia a: A prospective long-term follow-up comparing plasma-derived and recombinant products
-
DOI 10.1055/s-2002-32664
-
Kreuz W, Ettingshausen CE, Zyschka A, et al. Inhibitor development in previously untreated patients with hemophilia A: a prospective long-term follow-up comparing plasma-derived and recombinant products. Semin Thromb Hemost 2002; 28: 285-90. (Pubitemid 34634343)
-
(2002)
Seminars in Thrombosis and Hemostasis
, vol.28
, Issue.3
, pp. 285-290
-
-
Kreuz, W.1
Escuriola Ettingshausen, C.2
Zyschka, A.3
Oldenburg, J.4
Martinez Saguer, I.5
Ehrenforth, S.6
Klingebiel, T.7
-
28
-
-
0034917204
-
Purity of factor VIII product and incidence of inhibitors in previously untreated patients with haemophilia a
-
DOI 10.1046/j.1365-2516.2001.00513.x
-
Mauser-Bunschoten EP, van der Bom JG, Bongers M, et al. Purity of factor VIII product and incidence of inhibitors in previously untreated patients with haemophilia A. Haemophilia 2001; 7: 364-8. (Pubitemid 32677654)
-
(2001)
Haemophilia
, vol.7
, Issue.4
, pp. 364-368
-
-
Mauser-Bunschoten, E.P.1
Van Der Bom, J.G.2
Bongers, M.3
Twijnstra, M.4
Roosendaal, G.5
Fischer, K.6
Van Den Berg, H.M.7
-
29
-
-
30344434999
-
Influence of the type of factor VIII concentrate on the incidence of factor VIII inhibitors in previously untreated patients with severe hemophilia A
-
Goudemand J, Rothschild C, Demiguel V, et al. Influence of the type of factor VIII concentrate on the incidence of factor VIII inhibitors in previously untreated patients with severe hemophilia A. Blood 2006; 107: 46-51.
-
(2006)
Blood
, vol.107
, pp. 46-51
-
-
Goudemand, J.1
Rothschild, C.2
Demiguel, V.3
-
30
-
-
33846922841
-
Early factor VIII exposure and subsequent inhibitor development in children with severe haemophilia A
-
Chalmers EA, Brown SA, Keeling D, et al. Early factor VIII exposure and subsequent inhibitor development in children with severe haemophilia A. Haemophilia 2007; 13: 149-55.
-
(2007)
Haemophilia
, vol.13
, pp. 149-155
-
-
Chalmers, E.A.1
Brown, S.A.2
Keeling, D.3
-
31
-
-
34249711370
-
Recombinant versus plasma-derived factor VIII products and the development of inhibitors in previously untreated patients with severe hemophilia A: The CANAL cohort study
-
DOI 10.1182/blood-2006-11-056317
-
Gouw SC, van der Bom JG, Auerswald G, et al. Recombinant versus plasma-derived factor VIII products and the development of inhibitors in previously untreated patients with severe hemophilia A: the CANAL cohort study. Blood 2007; 109: 4693-7. (Pubitemid 46827760)
-
(2007)
Blood
, vol.109
, Issue.11
, pp. 4693-4697
-
-
Gouw, S.C.1
Van Der Bom, J.G.2
Auerswald, G.3
Ettinghausen, C.E.4
Tedgard, U.5
Van Den Berg, H.M.6
-
32
-
-
77955945267
-
Inhibitor incidence in previously untreated patients (PUPs) with hemophilia A and B. A prospective multicenter study of the pediatric study group of the German, Swiss and Austrian Society of Thrombosis and Hemostasis (GTH)
-
The GTH-PUP-Study Group Scharrer I, Schramm W, eds. New York, NY: Springer Berlin Heidelberg
-
Kreuz W, Auerswald G, Budde U, et al. Inhibitor incidence in previously untreated patients (PUPs) with hemophilia A and B. A prospective multicenter study of the pediatric study group of the German, Swiss and Austrian Society of Thrombosis and Hemostasis (GTH). The GTH-PUP-Study Group. In: Scharrer I, Schramm W, eds. 35th Hemophilia Symposium. New York, NY: Springer Berlin Heidelberg; 2006:34-7.
-
(2006)
35th Hemophilia Symposium
, pp. 34-37
-
-
Kreuz, W.1
Auerswald, G.2
Budde, U.3
-
33
-
-
0026583950
-
Treatment of hemophilia a with a highly purified factor VIII concentrate prepared by anti-FVIIIc immunoaffinity chromatography
-
Addiego JE Jr, Gomperts E, Liu SL, et al. Treatment of hemophilia A with a highly purified factor VIII concentrate prepared by anti-FVIIIc immunoaffinity chromatography. Thromb Haemost 1992; 67: 19-27.
-
(1992)
Thromb Haemost
, vol.67
, pp. 19-27
-
-
Addiego Jr., J.E.1
Gomperts, E.2
Liu, S.L.3
-
34
-
-
15344351616
-
Full-length sucrose-formulated recombinant factor VIII for treatment of previously untreated or minimally treated young children with severe haemophilia A: Results of an international clinical investigation
-
DOI 10.1160/TH03-10-0643
-
Kreuz W, Gill JC, Rothschild C, et al. Full-length sucrose-formulated recombinant factor VIII for treatment of previously untreated or minimally treated young children with severe haemophilia A: results of an international clinical investigation. Thromb Haemost 2005; 93: 457-67. (Pubitemid 40392533)
-
(2005)
Thrombosis and Haemostasis
, vol.93
, Issue.3
, pp. 457-467
-
-
Kreuz, W.1
Gill, J.C.2
Rothschild, C.3
Manco-Johnson, M.J.4
Lusher, J.M.5
Kellermann, E.6
Gorina, E.7
Larson, P.J.8
-
35
-
-
38349109840
-
Safety and efficacy of sucrose-formulated full-length recombinant factor VIII: Experience in the standard clinical setting
-
Musso R, Santagostino E, Faradji A, et al. Safety and efficacy of sucrose-formulated full-length recombinant factor VIII: experience in the standard clinical setting. Thromb Haemost 2008; 99: 52-8.
-
(2008)
Thromb Haemost
, vol.99
, pp. 52-58
-
-
Musso, R.1
Santagostino, E.2
Faradji, A.3
-
36
-
-
0038383605
-
The epidemiology of inhibitors in haemophilia a: A systematic review
-
Wight J, Paisley S. The epidemiology of inhibitors in haemophilia A: a systematic review. Haemophilia 2003; 9: 418-35. (Pubitemid 36874391)
-
(2003)
Haemophilia
, vol.9
, Issue.4
, pp. 418-435
-
-
Wight, J.1
Paisley, S.2
-
37
-
-
1542301024
-
Reported inhibitor incidence in FVIII PUP studies: Comparing apples with oranges?
-
Scharrer I, Ehrlich HJ. Reported inhibitor incidence in FVIII PUP studies: comparing apples with oranges? Haemophilia 2004; 10: 197-8.
-
(2004)
Haemophilia
, vol.10
, pp. 197-198
-
-
Scharrer, I.1
Ehrlich, H.J.2
-
38
-
-
77954506432
-
Rate of inhibitor development in previously-untreated hemophilia a patients treated with plasma-derived or recombinant factor VIII concentrates. A systematic review
-
Epub ahead of print
-
Iorio A, Halimeh S, Holzhauer S, et al. Rate of inhibitor development in previously-untreated hemophilia a patients treated with plasma-derived or recombinant factor VIII concentrates. A systematic review. J Thromb Haemost 2010:[Epub ahead of print].
-
(2010)
J Thromb Haemost
-
-
Iorio, A.1
Halimeh, S.2
Holzhauer, S.3
-
39
-
-
0347662157
-
Surveillance for factor VIII inhibitor development in the Canadian hemophilia a population following the widespread introduction of recombinant factor VIII replacement therapy
-
DOI 10.1016/S0955-3886(98)00024-1, PII S0955388698000241
-
Giles AR, Rivard GE, Teitel J, Walker I. Surveillance for factor VIII inhibitor development in the Canadian Hemophilia A population following the widespread introduction of recombinant factor VIII replacement therapy. Transfus Sci 1998; 19: 139-48. (Pubitemid 28438925)
-
(1998)
Transfusion Science
, vol.19
, Issue.2
, pp. 139-148
-
-
Giles, A.R.1
Rivard, G.E.2
Teitel, J.3
Walker, I.4
-
40
-
-
0030044206
-
Immune tolerance and the immune modulation protocol
-
Berntorp E, Nilsson IM. Immune tolerance and the immune modulation protocol. Vox Sang 1996; 70(Suppl 1): 36-41.
-
(1996)
Vox Sang
, vol.70
, Issue.SUPPL. 1
, pp. 36-41
-
-
Berntorp, E.1
Nilsson, I.M.2
-
41
-
-
0034524781
-
Variation in inhibitor reactivity in acquired haemophilia a with different concentrates
-
DOI 10.1046/j.1365-2257.2000.00328.x
-
Sukhu K, Keeling DM, Giangrande PL. Variation in inhibitor reactivity in acquired haemophilia A with different concentrates. Clin Lab Haematol 2000; 22: 287-90. (Pubitemid 32047103)
-
(2000)
Clinical and Laboratory Haematology
, vol.22
, Issue.5
, pp. 287-290
-
-
Sukhu, K.1
Keeling, D.M.2
Giangrande, P.L.F.3
-
42
-
-
2542560221
-
The role of plasma-derived factor VIII/von Willebrand factor concentrates in the treatment of hemophilia a patients
-
EREP05
-
Auerswald G, Spranger T, Brackmann HH. The role of plasma-derived factor VIII/von Willebrand factor concentrates in the treatment of hemophilia A patients. Haematologica 2003; 88: EREP05.
-
(2003)
Haematologica
, vol.88
-
-
Auerswald, G.1
Spranger, T.2
Brackmann, H.H.3
-
43
-
-
25444521967
-
Immune tolerance induction with highly purified plasma-derived factor VIII containing von Willebrand factor in hemophilia A patients with high-responding inhibitors
-
Orsini F, Rotschild C, Beurrier P, et al. Immune tolerance induction with highly purified plasma-derived factor VIII containing von Willebrand factor in hemophilia A patients with high-responding inhibitors. Haematologica. 2005; 90: 1288-90.
-
(2005)
Haematologica
, vol.90
, pp. 1288-1290
-
-
Orsini, F.1
Rotschild, C.2
Beurrier, P.3
-
44
-
-
40349087270
-
The use of factor VIII/von Willebrand factor concentrate for immune tolerance induction in haemophilia a patients with high-titre inhibitors: Association of clinical outcome with inhibitor epitope profile
-
DOI 10.1111/j.1365-2516.2007.01620.x
-
Greninger DA, Saint-Remy JM, Jacquemin M, et al. The use of factor VIII/von Willebrand factor concentrate for immune tolerance induction in haemophilia A patients with high-titre inhibitors: association of clinical outcome with inhibitor epitope profile. Haemophilia 2007; 14: 295-302. (Pubitemid 351338690)
-
(2008)
Haemophilia
, vol.14
, Issue.2
, pp. 295-302
-
-
Greninger, D.A.1
Saint-Remy, J.M.2
Jacquemin, M.3
Benhida, A.4
Dimichele, D.M.5
-
45
-
-
37749029633
-
Immune tolerance therapy utilizing factor VIII/von Willebrand factor concentrate in haemophilia A patients with high titre factor VIII inhibitors
-
Kurth MA, Dimichele D, Sexauer C, et al. Immune tolerance therapy utilizing factor VIII/von Willebrand factor concentrate in haemophilia A patients with high titre factor VIII inhibitors. Haemophilia 2007; 14: 50-55.
-
(2007)
Haemophilia
, vol.14
, pp. 50-55
-
-
Kurth, M.A.1
Dimichele, D.2
Sexauer, C.3
-
46
-
-
34447287337
-
Immune tolerance induction with a high purity von Willebrand factor/VIII complex concentrate in haemophilia A patients with inhibitors at high risk of a poor response
-
Gringeri A, Musso R, Mazzucconi MG, et al. Immune tolerance induction with a high purity von Willebrand factor/VIII complex concentrate in haemophilia A patients with inhibitors at high risk of a poor response. Haemophilia 2007; 13: 373-9.
-
(2007)
Haemophilia
, vol.13
, pp. 373-379
-
-
Gringeri, A.1
Musso, R.2
Mazzucconi, M.G.3
-
47
-
-
34347360724
-
International workshop on immune tolerance induction: Consensus recommendations
-
Dimichele DM, Hoots WK, Pipe SW, et al. International workshop on immune tolerance induction: consensus recommendations. Haemophilia 2007; 13(Suppl 1): 1-22.
-
(2007)
Haemophilia
, vol.13
, Issue.SUPPL. 1
, pp. 1-22
-
-
Dimichele, D.M.1
Hoots, W.K.2
Pipe, S.W.3
-
48
-
-
78049303656
-
International prospective randomized immune tolerance (ITI) study: Preliminary results of therapeutic efficacy and safety
-
on behalf of the International Immune Tolerance Study Group. abstract 07S03
-
Dimichele DM, Goldberg I, Foulkes M, on behalf of the International Immune Tolerance Study Group. International prospective randomized immune tolerance (ITI) study: preliminary results of therapeutic efficacy and safety [abstract 07S03]. Haemophilia 2010; 16(Suppl 4): 29.
-
(2010)
Haemophilia
, vol.16
, Issue.SUPPL. 4
, pp. 29
-
-
Dimichele, D.M.1
Goldberg, I.2
Foulkes, M.3
|