Fracture toughness and compressive properties of cancellous bone at the head of the femur and relationships to non-invasive skeletal assessment measurements

Medical Engineering and Physics

Volumn 32, Issue 9, 2010, Pages 991-997

  Cook, R B ^a   Curwen, C ^b   Tasker, T ^b   Zioupos, P ^c  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b GLOUCESTERSHIRE ROYAL HOSPITAL   (United Kingdom)

^c CRANFIELD UNIVERSITY   (United Kingdom)

Author keywords

Cancellous bone; Fracture toughness; Osteoporosis; Quantitative ultrasound; QUS; Strength

Indexed keywords

CANCELLOUS BONE; OSTEOPOROSIS; QUANTITATIVE ULTRASOUNDS; QUS; STRENGTH;

BONE; COMPRESSIVE STRENGTH; FORECASTING; FRACTURE; SURGERY; ULTRASONICS;

FRACTURE TOUGHNESS;

ADULT; ARTICLE; BONE DENSITY; BONE EXAMINATION; BONE RADIOGRAPHY; CANCELLOUS BONE; COMPRESSIVE STRENGTH; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; FEMUR FRACTURE; FEMUR HEAD; FEMUR NECK FRACTURE; HUMAN; HUMAN TISSUE; INTERMETHOD COMPARISON; MALE; NON INVASIVE MEASUREMENT; POROSITY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RISK ASSESSMENT;

AGED; AGED, 80 AND OVER; BIOMECHANICS; BONE DENSITY; COMPRESSIVE STRENGTH; FEMALE; FEMUR HEAD; FRACTURES, BONE; HUMANS; MALE; MIDDLE AGED; RISK ASSESSMENT;

EID: 78049242401     PISSN: 13504533     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.medengphy.2010.06.014     Document Type: Article

References (31)

1. Linde F., Hvid I., Madsen F. The effect of specimen geometry on the mechanical behaviour of trabecular bone specimens. J. Biomech. 1992, 25:359-368.
2. Li B., Aspden R.M. Composition and mechanical properties of cancellous bone from the femoral head of patients with osteoporosis and osteoarthritis. J. Bone Miner. Res. 1997, 12:641-651.
3. Kopperdahl D.L., Keaveny T.M. Yield strain behavior of trabecular bone. J. Biomech. 1998, 31:601-608.
4. Cook R.B., Zioupos P. The fracture toughness of cancellous bone. J. Biomech. 2009, 42:2054-2060.
5. Kanis J.A., Johnell O., Oden A., Johansson H., McCloskey E. FRAX and the assessment of fracture probability in men and women from the UK. Osteoporosis Int. 2008, 19:385-397.
6. Kanis J.A., Oden A., Johansson H., Borgström F., Ström O., McCloskey E. FRAX and its applications to clinical practice. Bone 2009, 44:734-743.
7. Cook R.B., Collin D., Tucker J., Zioupos P. Comparison of questionnaire and quantitative ultrasound techniques as screening tools for DXA. Osteoporosis Int. 2005, 16:1565-1575.
8. Cook R.B., Collin D., Tucker J., Zioupos P. The ability of peripheral quantitative ultrasound to identify patients with low bone mineral density in the hip or spine. Ultrasound Med. Biol. 2005, 31:625-632.
9. Cook, R.B. Non-invasively assessed skeletal bone status and its relationship to the biomechanical properties and condition of cancellous bone. PhD Thesis. Cranfield University; 2005. https://dspace.lib.cranfield.ac.uk/bitstream/1826/1032/1/Thesis.pdf.
10. Minnock E., Cook R., Collins D., Tucker J., Zioupos P. Using risk factors and quantitative ultrasound to identify postmenopausal Caucasian women at risk of osteoporosis. J. Clin. Densitom. 2008, 11:485-493.
11. Zioupos P., Cook R.B., Hutchinson J.R. Some basic relationships between density values in cancellous and cortical bone. J. Biomech. 2008, 41:1961-1968.
12. Dubois E.F.L., van den Bergh J.P.W., Smals A.G.H., van de Meerendonk C.W.D., Zwinderman A.H., Schweitzer D.H. Comparison of quantitative ultrasound parameters with dual energy X-ray absorptiometry in pre- and postmenopausal women. Neth. J. Med. 2001, 58:62-70.
13. Jørgensen H.L., Hassager C. Improved reproducibility of broadband ultrasound attenuation of the Os Calcis by using a specific region of interest. Bone 1997, 21:109-112.
14. Krestan C.R., Grampp S., Resch-Holeczke A., Henk C.B., Imhof H., Resch H. Diagnostic disagreement of imaging quantitative sonography of the calcaneus with dual X-ray absorptiometry of the spine and femur. Am. J. Roentgenol. 2001, 177:213-216.
15. Njeh C.F., Hans D., Li J., Fan B., Fuerst T., He Y.Q., Tsuda-Futami E., Lu Y., Wu C.Y., Genant H.K. Comparison of six calcaneal quantitative ultrasound devices: precision and hip fracture discrimination. Osteoporosis Int. 2000, 11:1051-1062.
16. Njeh C.F., Chen M.B., Fan B., Grigorian M., Shepherd J.A., Saeed I., Genant H.K. Evaluation of a gel-coupled quantitative ultrasound device for bone status assessment. Ultrasound Med. Biol. 2001, 20:1219-1228.
17. Sørensen H.A., Jørgensen N.R., Jensen J.E., Rasmussen A.M., Hansen B., Nielsen S.P., Sørensen O.H. Comparison of quantitative ultrasound and dual x-ray absorptiometry in estrogen-treated early postmenopausal women. J. Clin. Densitom. 2001, 4:97-104.
18. Njeh C.F., Wu C., Fan B., Hans D., Fuerst T., He Y., Genant H.K. Estimation of wrist fracture load using phalangeal speed of sound: an in vitro study. Ultrasound Med. Biol. 2000, 26:1517-1523.
19. Ashman R.B., Corin J.D., Turner C.H. Elastic properties of cancellous bone measurements by an ultrasonic technique. J. Biomech. 1987, 20:979-986.
20. Ashman R.B., Rho J.-Y. Elastic modulus of trabecular bone material. J. Biomech. 1988, 21:177-181.
21. Ho Ba Tho M.-C., Rho J.Y., Ashman R.B. Anatomical variation of human cancellous bone mechanical properties in-vitro. Stud. Health Technol. Inform. 1997, 40:157-173.
22. Bouxsein M.L., Radloff S.E. Quantitative ultrasound of the calcaneus reflects the mechanical properties of calcaneal trabecular bone. J. Bone Miner. Res. 1997, 12:839-846.
23. Lochmüller E.-M., Müller R., Kuhn V., Lill C.A., Eckstein F. Can novel densitometric techniques replace or improve DXA in predicting bone strength in osteoporosis at the hip and other skeletal sites?. J. Bone Miner. Res. 2003, 18:906-912.
24. Nicholson P.H., Lowet G., Cheng X.G., Boonen S., van der Perre G., Dequeker J. Assessment of the strength of the proximal femur in vitro: relationship with ultrasonic measurements of the calcaneus. Bone 1997, 20:219-224.
25. Wu C., Hans D., He Y., Fan B., Njeh C.F., Augat P., Richards J., Genant H.K. Prediction of bone strength of distal forearm using radius bone mineral density and phalangeal speed of sound. Bone 2000, 26:529-533.
26. Han S., Medige J., Faran K., Feng Z., Ziv I. The ability of quantitative ultrasound to predict the mechanical properties of trabecular bone under different strain rates. Med. Eng. Phys. 1997, 19:742-747.
27. Hans D., Wu C., Njeh C., Zhao S., Augat P., Newitt D., Link T., Lu Y., Majumdar S., Genant H.K. Ultrasound velocity of trabecular cubes reflects mainly bone density and elasticity. Calcified Tissue Int. 1999, 64:18-23.
28. Langton C.M., Njeh C.F., Hodgskinson R., Currey J.D. Prediction of mechanical properties of the human calcaneus by broadband ultrasound attenuation. Bone 1996, 18:495-503.
29. Njeh C.F., Kuo C.W., Langton C.M., Atrah H.I., Boivin C.M. Prediction of human femoral bone strength using ultrasound velocity and BMD: an in vitro study. Osteoporosis Int. 1997, 7:471-477.
30. Drozdzowska B., Pluskiewicz W., Prezedlacki J. Prediction of the biomechanical properties of cancellous bone using ultrasound velocity and bone mineral density - an in vitro study. Med. Sci. Monit. 2002, 8:15-20.
31. Gluer C.-C., Wu C.Y., Genant H.K. Broadband ultrasound attenuation signals depend on trabecular orientation: an in vitro study. Osteoporosis Int. 1993, 3:185-191.