Invited review: Inbred strains should replace outbred stocks in toxicology, safety testing, and drug development

Toxicologic Pathology

Volumn 38, Issue 5, 2010, Pages 681-690

  Festing, Michael F W ^a  

^a Understanding Animal Research   (United Kingdom)

Author keywords

attrition rates.; chloramphenicol; drug development; inbred strains; outbred stocks; safety pharmacology; toxicity testing

Indexed keywords

CHLORAMPHENICOL;

DRUG DEVELOPMENT; DRUG SAFETY; GENE EXPRESSION PROFILING; GENETIC VARIABILITY; INBRED STRAIN; MOUSE STRAIN; NONHUMAN; OUTBRED STRAIN; PRIORITY JOURNAL; RAT STRAIN; REVIEW; TOXICITY TESTING; ANIMAL; DRUG SCREENING; GENETICS; METHODOLOGY;

ANIMALIA;

ANIMALS; ANIMALS, INBRED STRAINS; DRUG EVALUATION, PRECLINICAL; TOXICITY TESTS;

EID: 77958616421     PISSN: 01926233     EISSN: 15331601     Source Type: Journal    
DOI: 10.1177/0192623310373776     Document Type: Review

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