Improvement of intestinal absorption of poorly absorbable drugs by polyamidoamine (PAMAM) dendrimers as novel absorption enhancers

Yakugaku Zasshi

Volumn 130, Issue 9, 2010, Pages 1123-1127

  Yamamoto, Akira ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Absorption enhancement; Absorption enhancer; Drug absorption; Intestinal absorption; Intestinal toxicity; Polyamidoamine (PAMAM) dendrimer

Indexed keywords

6 CARBOXYFLUORESCEIN; CALCITONIN; DENDRIMER; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; INSULIN; LACTATE DEHYDROGENASE; POLYAMIDOAMINE; 6-CARBOXYFLUORESCEIN; FLUORESCEIN DERIVATIVE; MACROMOLECULE; PAMAM STARBURST;

CONCENTRATION (PARAMETERS); CONFERENCE PAPER; DRUG ABSORPTION; ENZYME ACTIVITY; INTESTINE ABSORPTION; MEMBRANE DAMAGE; MOLECULAR WEIGHT; NONHUMAN; RAT; SAFETY; SMALL INTESTINE; ANIMAL; DRUG DELIVERY SYSTEM; DRUG DESIGN; HUMAN; INTESTINE MUCOSA; MACROMOLECULE; METABOLISM;

ANIMALS; CALCITONIN; DENDRIMERS; DRUG DELIVERY SYSTEMS; DRUG DESIGN; FLUORESCEINS; HUMANS; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; INTESTINE, SMALL; MACROMOLECULAR SUBSTANCES; RATS;

EID: 77958606883     PISSN: 00316903     EISSN: 13475231     Source Type: Journal    
DOI: 10.1248/yakushi.130.1123     Document Type: Conference Paper

References (11)

1. Lee V. H. L., Yamamoto A., Adv. Drug Delivery Rev., 4, 171-207 (1990).
2. Lee V. H. L., Yamamoto A., Kompella U. B., Crit. Rev. Ther. Drug Carrier Syst., 8, 91-192 (1991).
3. Yamamoto A., Tatsumi H., Maruyama M., Uchiyama T., Okada N., Fujita T., J. Pharmacol. Exp. Ther., 296, 84-90 (2001).
4. Fetih G., Habib F., Okada N., Fujita T., Attia M., Yamamoto A., J. Control. Release, 106, 287-297 (2005).
5. Gao Y., He L., Katsumi H., Sakane T., Fujita T., Yamamoto A., Int. J. Pharm., 354, 126-134 (2008).
6. Gao Y., He L., Katsumi H., Sakane T., Fujita T., Yamamoto A., Int. J. Pharm., 359, 70-78 (2008).
7. Miyake M., Minami T., Hirota M., Toguchi H., Odomi M., Ogawara K., Higaki K., Kimura T., J. Control. Release, 111, 27-34 (2006).
8. Morishita M., Kamei N., Ehara J., Isowa K., Takayama K., J. Control. Release, 118, 177-184 (2007).
9. Kondoh M., Masuyama A., Takahashi A., Asano N., Mizuguchi H., Koizumi N., Fujii M., Hayakawa T., Horiguchi Y., Watanabe Y., Mol. Pharmacol., 67, 749-756 (2005).
10. Fetih G., Lindberg S., Itoh K., Okada N., Fujita T., Habib F., Artursson P., Attia M., Yamamoto A., Int. J. Pharm., 293, 127-135 (2005).
11. Lin Y., Fujimori T., Kawaguchi N., Tsujimoto Y., Nishimi M., Dong Z., Katsumi H., Sakane T., Yamamoto A., J. Control. Release. (in press)