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Volumn 5, Issue 9, 2010, Pages 1-9

Differences in muscle and adipose tissue gene expression and cardio-metabolic risk factors in the members of physical activity discordant twin pairs

Author keywords

[No Author keywords available]

Indexed keywords

BRANCHED CHAIN AMINO ACID; GENOMIC RNA; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; POLYUNSATURATED FATTY ACID; TRIACYLGLYCEROL;

EID: 77958598071     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0012609     Document Type: Article
Times cited : (62)

References (41)
  • 2
    • 70249134919 scopus 로고    scopus 로고
    • Molecular networks as sensors and drivers of common human diseases
    • Schadt EE (2009) Molecular networks as sensors and drivers of common human diseases. Nature 46: 218-223.
    • (2009) Nature , vol.46 , pp. 218-223
    • Schadt, E.E.1
  • 3
    • 0032506959 scopus 로고    scopus 로고
    • Relationship of leisuretime physical activity and mortality
    • The Finnish Twin Cohort
    • Kujala UM, Kaprio J, Sarna S, Koskenvuo M (1998) Relationship of leisuretime physical activity and mortality. The Finnish Twin Cohort. JAMA 279: 440-444.
    • (1998) JAMA , vol.279 , pp. 440-444
    • Kujala, U.M.1    Kaprio, J.2    Sarna, S.3    Koskenvuo, M.4
  • 4
    • 0037076018 scopus 로고    scopus 로고
    • Exercise capacity and mortality among men referred for exercise testing
    • Myers J, Prakash M, Froelicher V, Do D, Partington S, et al. (2002) Exercise capacity and mortality among men referred for exercise testing. NEJM 346: 793-801.
    • (2002) NEJM , vol.346 , pp. 793-801
    • Myers, J.1    Prakash, M.2    Froelicher, V.3    do, D.4    Partington, S.5
  • 5
    • 0038690458 scopus 로고    scopus 로고
    • Occurrence of chronic disease in former top-level athletes
    • Predominance of benefits, risks or selection effects?
    • Kujala UM, Marti P, Kaprio J, Hernelahti M, Tikkanen H, et al. (2003) Occurrence of chronic disease in former top-level athletes. Predominance of benefits, risks or selection effects? Sports Med 33: 553-561.
    • (2003) Sports Med , vol.33 , pp. 553-561
    • Kujala, U.M.1    Marti, P.2    Kaprio, J.3    Hernelahti, M.4    Tikkanen, H.5
  • 6
    • 19944431011 scopus 로고    scopus 로고
    • Cardiovascular risk factors emerge after artificial selection for low aerobic capacity
    • Wisløff U, Najjar SM, Ellingsen O, Haram PM, Swoap S, et al. (2005) Cardiovascular risk factors emerge after artificial selection for low aerobic capacity. Science 307: 418-420.
    • (2005) Science , vol.307 , pp. 418-420
    • Wisløff, U.1    Najjar, S.M.2    Ellingsen, O.3    Haram, P.M.4    Swoap, S.5
  • 7
    • 57149098106 scopus 로고    scopus 로고
    • Physical Activity Guidelines Advisory Committee, Washington, DC: U.S. Department of Health and Human Services
    • Physical Activity Guidelines Advisory Committee (2008) Physical Activity Guidelines Advisory Committee Report, 2008. Washington, DC: U.S. Department of Health and Human Services.
    • (2008) Physical Activity Guidelines Advisory Committee Report, 2008
  • 8
    • 65649117349 scopus 로고    scopus 로고
    • Cardiorespiratory fitness as a quantitative predictor of all-cause mortality and cardiovascular events in healthy men and women
    • Kodama S, Saito K, Tanaka S, Maki M, Yachi Y, et al. (2009) Cardiorespiratory fitness as a quantitative predictor of all-cause mortality and cardiovascular events in healthy men and women. JAMA 301: 2024-2035.
    • (2009) JAMA , vol.301 , pp. 2024-2035
    • Kodama, S.1    Saito, K.2    Tanaka, S.3    Maki, M.4    Yachi, Y.5
  • 9
    • 68549086921 scopus 로고    scopus 로고
    • Evidence of the effects of exercise therapy in the treatment of chronic disease
    • Kujala UM (2009) Evidence of the effects of exercise therapy in the treatment of chronic disease. Br J Sports Med 43: 550-555.
    • (2009) Br J Sports Med , vol.43 , pp. 550-555
    • Kujala, U.M.1
  • 10
    • 0035015391 scopus 로고    scopus 로고
    • Response of blood lipids to exercise training alone or combined with dietary intervention
    • Leon AS, Sanchez OA (2001) Response of blood lipids to exercise training alone or combined with dietary intervention. Med Sci Sports Exerc 33: S502-515.
    • (2001) Med Sci Sports Exerc , vol.33
    • Leon, A.S.1    Sanchez, O.A.2
  • 11
    • 0035112481 scopus 로고    scopus 로고
    • Invited review: Contractile activity-induced mitochondrial biogenesis in skeletal muscle
    • Hood DA (2001) Invited review: contractile activity-induced mitochondrial biogenesis in skeletal muscle. J Appl Physiol 90: 1137-1157.
    • (2001) J Appl Physiol , vol.90 , pp. 1137-1157
    • Hood, D.A.1
  • 12
    • 37249066135 scopus 로고    scopus 로고
    • Exercise training-induced improvements in insulin action
    • Hawley JA, Lessard SJ (2008) Exercise training-induced improvements in insulin action. Acta Physiol (Oxf) 192: 127-135.
    • (2008) Acta Physiol (Oxf) , vol.192 , pp. 127-135
    • Hawley, J.A.1    Lessard, S.J.2
  • 13
    • 72449176438 scopus 로고    scopus 로고
    • Exercise, abdominal obesity, skeletal muscle, and metabolic risk: Evidence for a dose response
    • Slentz CA, Houmard JA, Kraus WE (2009) Exercise, abdominal obesity, skeletal muscle, and metabolic risk: evidence for a dose response. Obesity 17(s3): S27-S33.
    • (2009) Obesity , vol.17 , Issue.s3
    • Slentz, C.A.1    Houmard, J.A.2    Kraus, W.E.3
  • 14
    • 76049118432 scopus 로고    scopus 로고
    • Intramuscular triacylglycerol and insulin resistance: Guilty as charged or wrongly accused?
    • Muoio DM (2010) Intramuscular triacylglycerol and insulin resistance: Guilty as charged or wrongly accused? Biochim Biophys Acta 1801: 281-288.
    • (2010) Biochim Biophys Acta , vol.1801 , pp. 281-288
    • Muoio, D.M.1
  • 15
    • 60849126439 scopus 로고    scopus 로고
    • Effects of 32-year leisure time physical activity discordance in twin pairs on health (TWINACTIVE Study): Aims, design and results for physical fitness
    • Leskinen T, Waller K, Mutikainen S, Aaltonen S, Ronkainen PHA, et al. (2009) Effects of 32-year leisure time physical activity discordance in twin pairs on health (TWINACTIVE Study): Aims, design and results for physical fitness. Twin Res Human Genetics 12: 108-117.
    • (2009) Twin Res Human Genetics , vol.12 , pp. 108-117
    • Leskinen, T.1    Waller, K.2    Mutikainen, S.3    Aaltonen, S.4    Ronkainen, P.H.A.5
  • 16
    • 70450273137 scopus 로고    scopus 로고
    • Leisure time physical activity and high-risk fat: A longitudinal population-based twin study
    • Leskinen T, Sipilä S, Alen M, Cheng S, Pietiläinen KH, et al. (2009) Leisure time physical activity and high-risk fat: A longitudinal population-based twin study. Int J Obes 33: 1211-1218.
    • (2009) Int J Obes , vol.33 , pp. 1211-1218
    • Leskinen, T.1    Sipilä, S.2    Alen, M.3    Cheng, S.4    Pietiläinen, K.H.5
  • 17
    • 39449085101 scopus 로고    scopus 로고
    • Associations between long-term physical activity, waist circumference and weight gain: A 30-year longitudinal twin study
    • Waller K, Kaprio J, Kujala UM (2008) Associations between long-term physical activity, waist circumference and weight gain: A 30-year longitudinal twin study. Int J Obes (Lond) 32: 353-361.
    • (2008) Int J Obes (Lond) , vol.32 , pp. 353-361
    • Waller, K.1    Kaprio, J.2    Kujala, U.M.3
  • 18
    • 58149389260 scopus 로고    scopus 로고
    • Introduction to symposium proceedings: The emerging interplay among muscle mitochondrial function, nutrition and disease
    • Short KR (2009) Introduction to symposium proceedings: the emerging interplay among muscle mitochondrial function, nutrition and disease. Am J Clin Nutr 89: 453S-454S.
    • (2009) Am J Clin Nutr , vol.89
    • Short, K.R.1
  • 19
    • 0014198263 scopus 로고
    • Effects of exercise on mitochondrial oxygen uptake and respiratory enzyme activity in skeletal muscle
    • Holloszy JO (1967) Effects of exercise on mitochondrial oxygen uptake and respiratory enzyme activity in skeletal muscle. J Biol Chem 242: 2278-2282.
    • (1967) J Biol Chem , vol.242 , pp. 2278-2282
    • Holloszy, J.O.1
  • 20
    • 0034927750 scopus 로고    scopus 로고
    • High-density lipoprotein binding to scavenger receptor-BI activates endothelial nitric oxide syntase
    • Yuhanna IS, Zhu Y, Cox BE, Hahner LD, Osborne-Lawrence S, et al. (2001) High-density lipoprotein binding to scavenger receptor-BI activates endothelial nitric oxide syntase. Nat Med 7: 853-857.
    • (2001) Nat Med , vol.7 , pp. 853-857
    • Yuhanna, I.S.1    Zhu, Y.2    Cox, B.E.3    Hahner, L.D.4    Osborne-Lawrence, S.5
  • 21
    • 67651093923 scopus 로고    scopus 로고
    • HDL-associated dehydroepiandrosterone fatty acyl esters: Enhancement of vasodilatatory effect of HDL
    • Paatela H, Mervaala E, Deb S, Wähä lä K, Tikkanen MJ (2009) HDL-associated dehydroepiandrosterone fatty acyl esters: Enhancement of vasodilatatory effect of HDL. Steroids 74: 814-818.
    • (2009) Steroids , vol.74 , pp. 814-818
    • Paatela, H.1    Mervaala, E.2    Deb, S.3    La Wähä, K.4    Tikkanen, M.J.5
  • 22
    • 12444296524 scopus 로고    scopus 로고
    • Failure of fat cell proliferation, mitochondrial function and fat oxidation results in ectopic fat storage, insulin resistance and type II diabetes mellitus
    • Heilbronn L, Smith SR, Ravussin E (2004) Failure of fat cell proliferation, mitochondrial function and fat oxidation results in ectopic fat storage, insulin resistance and type II diabetes mellitus. Int J Obes Relat Metab Disord 28: S12-S21.
    • (2004) Int J Obes Relat Metab Disord , vol.28
    • Heilbronn, L.1    Smith, S.R.2    Ravussin, E.3
  • 23
    • 33646559999 scopus 로고    scopus 로고
    • Role of amino acids in insulin signalling in adipocytes and their potential to decrease insulin resistance of adipose tissue
    • Hinault C, Van Obberghen E, Mothe-Satney I (2006) Role of amino acids in insulin signalling in adipocytes and their potential to decrease insulin resistance of adipose tissue. J Nutr Biochem 17: 374-378.
    • (2006) J Nutr Biochem , vol.17 , pp. 374-378
    • Hinault, C.1    van Obberghen, E.2    Mothe-Satney, I.3
  • 24
    • 41549125912 scopus 로고    scopus 로고
    • Global transcript profiles of fat in monozygotic twins discordant for BMI: Pathways behind acquired obesity
    • Pietiläinen KH, Naukkarinen J, Rissanen A, Saharinen J, Ellonen P, et al. (2008) Global transcript profiles of fat in monozygotic twins discordant for BMI: pathways behind acquired obesity. PLoS Med 5: e51.
    • (2008) PLoS Med , vol.5 , pp. 51
    • Pietiläinen, K.H.1    Naukkarinen, J.2    Rissanen, A.3    Saharinen, J.4    Ellonen, P.5
  • 25
    • 63449111894 scopus 로고    scopus 로고
    • A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance
    • Newgard CB, An J, Bain JR, Muehlbauer MJ, Stevens RD, et al. (2009) A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. Cell Metabolism 9: 311-326.
    • (2009) Cell Metabolism , vol.9 , pp. 311-326
    • Newgard, C.B.1    An, J.2    Bain, J.R.3    Muehlbauer, M.J.4    Stevens, R.D.5
  • 26
    • 50349102028 scopus 로고    scopus 로고
    • Acquired obesity and poor fitness impair expression of genes of mitochondrial oxidative phosphorylation in monozygotic twins discordant for obesity
    • Mustelin L, Pietiläinen KH, Rissanen A, Sovijä rvi AR, Piirilä P, et al. (2008) Acquired obesity and poor fitness impair expression of genes of mitochondrial oxidative phosphorylation in monozygotic twins discordant for obesity. Am J Physiol Endocrinol Metab 295: 148-154.
    • (2008) Am J Physiol Endocrinol Metab , vol.295 , pp. 148-154
    • Mustelin, L.1    Pietiläinen, K.H.2    Rissanen, A.3    Sovijä, R.V.I.4    Piirilä, A.R.P.5
  • 27
    • 61449266414 scopus 로고    scopus 로고
    • Serum saturated fatty acids containing triacylglycerols are better markers of insulin resistance than total serum triacylglycerol concentrations
    • Kotronen A, Velagapudi VR, Yetukuri L, Westerbacka J, Bergholm R, et al. (2009) Serum saturated fatty acids containing triacylglycerols are better markers of insulin resistance than total serum triacylglycerol concentrations. Diabetologia 52: 684-690.
    • (2009) Diabetologia , vol.52 , pp. 684-690
    • Kotronen, A.1    Velagapudi, V.R.2    Yetukuri, L.3    Westerbacka, J.4    Bergholm, R.5
  • 28
    • 44049092767 scopus 로고    scopus 로고
    • Signaling mechanisms in skeletal muscle: Acute responses and chronic adaptations to exercise
    • Röckl SC, Witczak CA, Goodyear LJ (2008) Signaling mechanisms in skeletal muscle: Acute responses and chronic adaptations to exercise. IUBMB Life 60: 145-153.
    • (2008) IUBMB Life , vol.60 , pp. 145-153
    • Röckl, S.C.1    Witczak, C.A.2    Goodyear, L.J.3
  • 30
    • 68949099630 scopus 로고    scopus 로고
    • Long-term leisure time physical activity and properties of bone: A twin study
    • Ma H, Leskinen T, Alen M, Cheng S, Sipilä S, et al. (2009) Long-term leisure time physical activity and properties of bone: A twin study. J Bone Mineral Res 24: 1427-1433.
    • (2009) J Bone Mineral Res , vol.24 , pp. 1427-1433
    • Ma, H.1    Leskinen, T.2    Alen, M.3    Cheng, S.4    Sipilä, S.5
  • 31
    • 78649810271 scopus 로고    scopus 로고
    • Gene expression centroids that link with low intrinsic aerobic exercise
    • in press, doi:10.1096/fj.10-157313
    • Kivelä R, Silvennoinen M, Lehti M, Rinnankoski-Tuikka R, Purhonen T, et al. (2010) Gene expression centroids that link with low intrinsic aerobic exercise.; FASEB J, in press, doi:10.1096/fj.10-157313.
    • (2010) FASEB J
    • Kivelä, R.1    Silvennoinen, M.2    Lehti, M.3    Rinnankoski-Tuikka, R.4    Purhonen, T.5
  • 32
    • 0020645217 scopus 로고
    • Response of succinate dehydrogenase activity in fibres of rabbit tibialis anterior muscle to chronic nerve stimulation
    • Pette D, Tyler KR (1983) Response of succinate dehydrogenase activity in fibres of rabbit tibialis anterior muscle to chronic nerve stimulation. J Physiol 338: 1-9.
    • (1983) J Physiol , vol.338 , pp. 1-9
    • Pette, D.1    Tyler, K.R.2
  • 33
    • 37649023136 scopus 로고    scopus 로고
    • Muscular transcriptome in postmenopausal women with or without hormone replacement
    • Pöllänen E, Ronkainen PH, Suominen H, Takala T, Koskinen S, et al. (2007) Muscular transcriptome in postmenopausal women with or without hormone replacement. Rejuvenation Res 10: 485-500.
    • (2007) Rejuvenation Res , vol.10 , pp. 485-500
    • Pöllänen, E.1    Ronkainen, P.H.2    Suominen, H.3    Takala, T.4    Koskinen, S.5
  • 34
    • 1342288026 scopus 로고    scopus 로고
    • Affy-analysis of Affymetrix GeneChip data at the probe level
    • Gautier L, Cope L, Bolstad BM, Irizarry RA (2004) Affy-analysis of Affymetrix GeneChip data at the probe level. Bioinformatics 20: 307-315.
    • (2004) Bioinformatics , vol.20 , pp. 307-315
    • Gautier, L.1    Cope, L.2    Bolstad, B.M.3    Irizarry, R.A.4
  • 35
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
    • Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, et al. (2005) Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 102: 15545-15550.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 15545-15550
    • Subramanian, A.1    Tamayo, P.2    Mootha, V.K.3    Mukherjee, S.4    Ebert, B.L.5
  • 36
    • 0038054341 scopus 로고    scopus 로고
    • PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
    • Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, et al. (2003) PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nature Genetics 4: 267-273.
    • (2003) Nature Genetics , vol.4 , pp. 267-273
    • Mootha, V.K.1    Lindgren, C.M.2    Eriksson, K.F.3    Subramanian, A.4    Sihag, S.5
  • 37
    • 54949084597 scopus 로고    scopus 로고
    • A systems biology strategy reveals biological pathways and plasma biomarker candidates for potentially toxic statin-induced changes in muscle
    • (doi:10.1371/journal.pone.0000097)
    • Laaksonen R, Katajamaa M, Päivä H, Sysi-Aho M, Saarinen L, et al. (2006) A systems biology strategy reveals biological pathways and plasma biomarker candidates for potentially toxic statin-induced changes in muscle. PLoS ONE 1: e97. (doi:10.1371/journal.pone.0000097).
    • (2006) PLoS ONE , vol.1 , pp. 97
    • Laaksonen, R.1    Katajamaa, M.2    Päivä, H.3    Sysi-Aho, M.4    Saarinen, L.5
  • 38
    • 33644867564 scopus 로고    scopus 로고
    • Mzmine, toolbox for processing and visualization of mass spectrometry based molecular profile data
    • Katajamaa M, Miettinen J, Oresic M (2006) Mzmine, toolbox for processing and visualization of mass spectrometry based molecular profile data. Bioinformatics 22: 634-636.
    • (2006) Bioinformatics , vol.22 , pp. 634-636
    • Katajamaa, M.1    Miettinen, J.2    Oresic, M.3
  • 39
    • 0036020892 scopus 로고    scopus 로고
    • A direct approach to false discovery rates
    • Storey JD (2002) A direct approach to false discovery rates. J R Stat Soc B 64: 479-498.
    • (2002) J R Stat Soc B , vol.64 , pp. 479-498
    • Storey, J.D.1
  • 40
    • 0033918632 scopus 로고    scopus 로고
    • A note on robust variance estimation for cluster-correlated data
    • Williams RL (2000) A note on robust variance estimation for cluster-correlated data. Biometrics 56: 645-646.
    • (2000) Biometrics , vol.56 , pp. 645-646
    • Williams, R.L.1
  • 41
    • 84875074722 scopus 로고    scopus 로고
    • The R Project for Statistical Computing website (accessed 2010)
    • The R Project for Statistical Computing website (accessed 2010) http://www.R-project.org.


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