-
2
-
-
0031837533
-
Huntington disease
-
10.1097/00005072-199805000-00001. 9596408
-
Huntington disease. JP Vonsattel M DiFiglia, J Neuropathol Exp Neurol 1998 57 369 384 10.1097/00005072-199805000-00001 9596408
-
(1998)
J Neuropathol Exp Neurol
, vol.57
, pp. 369-384
-
-
Vonsattel, J.P.1
Difiglia, M.2
-
3
-
-
11144237210
-
HAP1 and intracellular trafficking
-
10.1016/j.tips.2004.11.001. 15629196
-
HAP1 and intracellular trafficking. XJ Li SH Li, Trends Pharmacol Sci 2005 26 1 3 10.1016/j.tips.2004.11.001 15629196
-
(2005)
Trends Pharmacol Sci
, vol.26
, pp. 1-3
-
-
Li, X.J.1
Li, S.H.2
-
4
-
-
72949098095
-
Genetic and pharmacological inhibition of calcineurin corrects the BDNF transport defect in Huntington's disease
-
10.1186/1756-6606-2-33. 19860865
-
Genetic and pharmacological inhibition of calcineurin corrects the BDNF transport defect in Huntington's disease. JR Pineda R Pardo D Zala H Yu S Humbert F Saudou, Mol Brain 2009 2 33 10.1186/1756-6606-2-33 19860865
-
(2009)
Mol Brain
, vol.2
, pp. 33
-
-
Pineda, J.R.1
Pardo, R.2
Zala, D.3
Yu, H.4
Humbert, S.5
Saudou, F.6
-
5
-
-
63449090757
-
Huntingtin as an essential integrator of intracellular vesicular trafficking
-
10.1016/j.tcb.2009.01.005. 19269181
-
Huntingtin as an essential integrator of intracellular vesicular trafficking. JP Caviston EL Holzbaur, Trends Cell Biol 2009 19 147 155 10.1016/j.tcb.2009.01.005 19269181
-
(2009)
Trends Cell Biol
, vol.19
, pp. 147-155
-
-
Caviston, J.P.1
Holzbaur, E.L.2
-
6
-
-
77953846289
-
PARIS-htt: An optimised expression platform to study huntingtin reveals functional domains required for vesicular trafficking
-
10.1186/1756-6606-3-17. 20515468
-
pARIS-htt: an optimised expression platform to study huntingtin reveals functional domains required for vesicular trafficking. R Pardo M Molina-Calavita G Poizat G Keryer S Humbert F Saudou, Mol Brain 2010 3 17 10.1186/1756-6606-3- 17 20515468
-
(2010)
Mol Brain
, vol.3
, pp. 17
-
-
Pardo, R.1
Molina-Calavita, M.2
Poizat, G.3
Keryer, G.4
Humbert, S.5
Saudou, F.6
-
7
-
-
33744504676
-
Mechanisms of disease: Histone modifications in Huntington's disease
-
10.1038/ncpneuro0199. 16932577
-
Mechanisms of disease: Histone modifications in Huntington's disease. G Sadri-Vakili JH Cha, Nat Clin Pract Neurol 2006 2 330 338 10.1038/ncpneuro0199 16932577
-
(2006)
Nat Clin Pract Neurol
, vol.2
, pp. 330-338
-
-
Sadri-Vakili, G.1
Cha, J.H.2
-
8
-
-
68149134683
-
Nuclear accumulation of polyglutamine disease proteins and neuropathology
-
10.1186/1756-6606-2-21. 19575804
-
Nuclear accumulation of polyglutamine disease proteins and neuropathology. LS Havel S Li XJ Li, Mol Brain 2009 2 21 10.1186/1756-6606-2-21 19575804
-
(2009)
Mol Brain
, vol.2
, pp. 21
-
-
Havel, L.S.1
Li, S.2
Li, X.J.3
-
9
-
-
0033054555
-
Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin
-
10.1093/hmg/8.3.397. 9949199
-
Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin. G Schilling MW Becher AH Sharp HA Jinnah K Duan JA Kotzuk HH Slunt T Ratovitski JK Cooper NA Jenkins NG Copeland DL Price CA Ross DR Borchelt, Hum Mol Genet 1999 8 397 407 10.1093/hmg/8.3.397 9949199
-
(1999)
Hum Mol Genet
, vol.8
, pp. 397-407
-
-
Schilling, G.1
Becher, M.W.2
Sharp, A.H.3
Jinnah, H.A.4
Duan, K.5
Kotzuk, J.A.6
Slunt, H.H.7
Ratovitski, T.8
Cooper, J.K.9
Jenkins, N.A.10
Copeland, N.G.11
Price, D.L.12
Ross, C.A.13
Borchelt, D.R.14
-
10
-
-
0036165417
-
Mouse models of Huntington's disease
-
10.1016/S0165-6147(00)01884-8. 11804649
-
Mouse models of Huntington's disease. LB Menalled MF Chesselet, Trends Pharmacol Sci 2002 23 32 39 10.1016/S0165-6147(00)01884-8 11804649
-
(2002)
Trends Pharmacol Sci
, vol.23
, pp. 32-39
-
-
Menalled, L.B.1
Chesselet, M.F.2
-
11
-
-
51349162486
-
Rodent genetic models of Huntington disease
-
10.1016/j.nbd.2008.06.005. 18638556
-
Rodent genetic models of Huntington disease. MY Heng PJ Detloff RL Albin, Neurobiol Dis 2008 32 1 9 10.1016/j.nbd.2008.06.005 18638556
-
(2008)
Neurobiol Dis
, vol.32
, pp. 1-9
-
-
Heng, M.Y.1
Detloff, P.J.2
Albin, R.L.3
-
12
-
-
68949122506
-
IL-1/IL-1ra balance in the brain revisited - Evidence from transgenic mouse models
-
10.1016/j.bbi.2009.02.015. 19258032
-
IL-1/IL-1ra balance in the brain revisited - evidence from transgenic mouse models. S Spulber T Bartfai M Schultzberg, Brain Behav Immun 2009 23 573 579 10.1016/j.bbi.2009.02.015 19258032
-
(2009)
Brain Behav Immun
, vol.23
, pp. 573-579
-
-
Spulber, S.1
Bartfai, T.2
Schultzberg, M.3
-
13
-
-
0035487313
-
Cytokines and acute neurodegeneration
-
10.1038/35094583. 11584311
-
Cytokines and acute neurodegeneration. SM Allan NJ Rothwell, Nat Rev Neurosci 2001 2 734 744 10.1038/35094583 11584311
-
(2001)
Nat Rev Neurosci
, vol.2
, pp. 734-744
-
-
Allan, S.M.1
Rothwell, N.J.2
-
14
-
-
0031252311
-
Phenotypic and functional characterization of mice that lack the type i receptor for IL-1
-
9317135
-
Phenotypic and functional characterization of mice that lack the type I receptor for IL-1. MB Glaccum KL Stocking K Charrier JL Smith CR Willis C Maliszewski DJ Livingston JJ Peschon PJ Morrissey, J Immunol 1997 159 3364 3371 9317135
-
(1997)
J Immunol
, vol.159
, pp. 3364-3371
-
-
Glaccum, M.B.1
Stocking, K.L.2
Charrier, K.3
Smith, J.L.4
Willis, C.R.5
Maliszewski, C.6
Livingston, D.J.7
Peschon, J.J.8
Morrissey, P.J.9
-
15
-
-
26244445240
-
NF-kappaB in the survival and plasticity of neurons
-
10.1007/s11064-005-6961-x. 16187223
-
NF-kappaB in the survival and plasticity of neurons. MP Mattson, Neurochem Res 2005 30 883 893 10.1007/s11064-005-6961-x 16187223
-
(2005)
Neurochem Res
, vol.30
, pp. 883-893
-
-
Mattson, M.P.1
-
16
-
-
33747284324
-
Distinct roles of diverse nuclear factor-kappaB complexes in neuropathological mechanisms
-
10.1016/j.ejphar.2006.06.027. 16854410
-
Distinct roles of diverse nuclear factor-kappaB complexes in neuropathological mechanisms. M Pizzi P Spano, Eur J Pharmacol 2006 545 22 28 10.1016/j.ejphar.2006.06.027 16854410
-
(2006)
Eur J Pharmacol
, vol.545
, pp. 22-28
-
-
Pizzi, M.1
Spano, P.2
-
17
-
-
77952568816
-
Downregulation of NF-kappaB signaling by mutant huntingtin proteins induces oxidative stress and cell death
-
10.1007/s00018-010-0305-y. 20232225
-
Downregulation of NF-kappaB signaling by mutant huntingtin proteins induces oxidative stress and cell death. S Reijonen JP Kukkonen A Hyrskyluoto J Kivinen M Kairisalo N Takei D Lindholm L Korhonen, Cell Mol Life Sci 2010 67 1929 1941 10.1007/s00018-010-0305-y 20232225
-
(2010)
Cell Mol Life Sci
, vol.67
, pp. 1929-1941
-
-
Reijonen, S.1
Kukkonen, J.P.2
Hyrskyluoto, A.3
Kivinen, J.4
Kairisalo, M.5
Takei, N.6
Lindholm, D.7
Korhonen, L.8
-
18
-
-
4644307407
-
Activation of the IkappaB kinase complex and nuclear factor-kappaB contributes to mutant huntingtin neurotoxicity
-
10.1523/JNEUROSCI.2675-04.2004. 15371500
-
Activation of the IkappaB kinase complex and nuclear factor-kappaB contributes to mutant huntingtin neurotoxicity. A Khoshnan J Ko EE Watkin LA Paige PH Reinhart PH Patterson, J Neurosci 2004 24 7999 8008 10.1523/JNEUROSCI.2675-04.2004 15371500
-
(2004)
J Neurosci
, vol.24
, pp. 7999-8008
-
-
Khoshnan, A.1
Ko, J.2
Watkin, E.E.3
Paige, L.A.4
Reinhart, P.H.5
Patterson, P.H.6
-
19
-
-
0037791780
-
Interleukin-1 in the brain: Mechanisms of action in acute neurodegeneration
-
10.1111/j.1749-6632.2003.tb03136.x. 12794045
-
Interleukin-1 in the brain: mechanisms of action in acute neurodegeneration. HC Patel H Boutin SM Allan, Ann N Y Acad Sci 2003 992 39 47 10.1111/j.1749-6632.2003.tb03136.x 12794045
-
(2003)
Ann N y Acad Sci
, vol.992
, pp. 39-47
-
-
Patel, H.C.1
Boutin, H.2
Allan, S.M.3
-
20
-
-
0027501020
-
Interleukin-1 receptor antagonist
-
8379462
-
Interleukin-1 receptor antagonist. WP Arend, Adv Immunol 1993 54 167 227 8379462
-
(1993)
Adv Immunol
, vol.54
, pp. 167-227
-
-
Arend, W.P.1
-
21
-
-
49649117786
-
Accumulation of N-terminal mutant huntingtin in mouse and monkey models implicated as a pathogenic mechanism in Huntington's disease
-
10.1093/hmg/ddn175. 18558632
-
Accumulation of N-terminal mutant huntingtin in mouse and monkey models implicated as a pathogenic mechanism in Huntington's disease. CE Wang S Tydlacka AL Orr SH Yang RK Graham MR Hayden S Li AW Chan XJ Li, Hum Mol Genet 2008 17 2738 2751 10.1093/hmg/ddn175 18558632
-
(2008)
Hum Mol Genet
, vol.17
, pp. 2738-2751
-
-
Wang, C.E.1
Tydlacka, S.2
Orr, A.L.3
Yang, S.H.4
Graham, R.K.5
Hayden, M.R.6
Li, S.7
Chan, A.W.8
Li, X.J.9
-
22
-
-
29144460321
-
Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity
-
10.1083/jcb.200508072. 16365166
-
Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity. JY Shin ZH Fang ZX Yu CE Wang SH Li XJ Li, J Cell Biol 2005 171 1001 1012 10.1083/jcb.200508072 16365166
-
(2005)
J Cell Biol
, vol.171
, pp. 1001-1012
-
-
Shin, J.Y.1
Fang, Z.H.2
Yu, Z.X.3
Wang, C.E.4
Li, S.H.5
Li, X.J.6
-
23
-
-
0037444445
-
Mutant huntingtin causes context-dependent neurodegeneration in mice with Huntington's disease
-
12657678
-
Mutant huntingtin causes context-dependent neurodegeneration in mice with Huntington's disease. ZX Yu SH Li J Evans A Pillarisetti H Li XJ Li, J Neurosci 2003 23 2193 2202 12657678
-
(2003)
J Neurosci
, vol.23
, pp. 2193-2202
-
-
Yu, Z.X.1
Li, S.H.2
Evans, J.3
Pillarisetti, A.4
Li, H.5
Li, X.J.6
-
24
-
-
0035862896
-
Neurological abnormalities in a knock-in mouse model of Huntington's disease
-
10.1093/hmg/10.2.137. 11152661
-
Neurological abnormalities in a knock-in mouse model of Huntington's disease. CH Lin S Tallaksen-Greene WM Chien JA Cearley WS Jackson AB Crouse S Ren XJ Li RL Albin PJ Detloff, Hum Mol Genet 2001 10 137 144 10.1093/hmg/10.2.137 11152661
-
(2001)
Hum Mol Genet
, vol.10
, pp. 137-144
-
-
Lin, C.H.1
Tallaksen-Greene, S.2
Chien, W.M.3
Cearley, J.A.4
Jackson, W.S.5
Crouse, A.B.6
Ren, S.7
Li, X.J.8
Albin, R.L.9
Detloff, P.J.10
-
26
-
-
15944378214
-
Beta-Secretase, APP and Abeta in Alzheimer's disease
-
15709474
-
beta-Secretase, APP and Abeta in Alzheimer's disease. R Vassar, Subcell Biochem 2005 38 79 103 15709474
-
(2005)
Subcell Biochem
, vol.38
, pp. 79-103
-
-
Vassar, R.1
-
27
-
-
70349416042
-
Environmental neurotoxin dieldrin induces apoptosis via caspase-3-dependent proteolytic activation of protein kinase C delta (PKCdelta): Implications for neurodegeneration in Parkinson's disease
-
10.1186/1756-6606-1-12. 18945348
-
Environmental neurotoxin dieldrin induces apoptosis via caspase-3-dependent proteolytic activation of protein kinase C delta (PKCdelta): Implications for neurodegeneration in Parkinson's disease. AG Kanthasamy M Kitazawa Y Yang V Anantharam A Kanthasamy, Mol Brain 2008 1 12 10.1186/1756-6606-1-12 18945348
-
(2008)
Mol Brain
, vol.1
, pp. 12
-
-
Kanthasamy, A.G.1
Kitazawa, M.2
Yang, Y.3
Anantharam, V.4
Kanthasamy, A.5
-
28
-
-
79955694568
-
Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity
-
10.1186/1756-6606-1-17. 19021916
-
Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity. L Qiao,, et al. Mol Brain 2008 1 17 10.1186/1756-6606-1-17 19021916
-
(2008)
Mol Brain
, vol.1
, pp. 17
-
-
Qiao, L.1
-
29
-
-
64949185378
-
Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo
-
10.1186/1756-6606-2-5. 19203374
-
Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo. V Cullen M Lindfors J Ng A Paetau E Swinton P Kolodziej H Boston P Saftig J Woulfe MB Feany L Myllykangas MG Schlossmacher J Tyynela, Mol Brain 2009 2 5 10.1186/1756-6606-2-5 19203374
-
(2009)
Mol Brain
, vol.2
, pp. 5
-
-
Cullen, V.1
Lindfors, M.2
Ng, J.3
Paetau, A.4
Swinton, E.5
Kolodziej, P.6
Boston, H.7
Saftig, P.8
Woulfe, J.9
Feany, M.B.10
Myllykangas, L.11
Schlossmacher, M.G.12
Tyynela, J.13
-
30
-
-
0032802965
-
Actions of the pro-inflammatory cytokine IL-1 beta on central synaptic transmission
-
10.1017/S0958067099018928. 10481219
-
Actions of the pro-inflammatory cytokine IL-1 beta on central synaptic transmission. JJ O'Connor AN Coogan, Exp Physiol 1999 84 601 614 10.1017/S0958067099018928 10481219
-
(1999)
Exp Physiol
, vol.84
, pp. 601-614
-
-
O'Connor, J.J.1
Coogan, A.N.2
-
31
-
-
34547279579
-
Cytokines and neuronal ion channels in health and disease
-
17678965
-
Cytokines and neuronal ion channels in health and disease. B Viviani F Gardoni M Marinovich, Int Rev Neurobiol 2007 82 247 263 17678965
-
(2007)
Int Rev Neurobiol
, vol.82
, pp. 247-263
-
-
Viviani, B.1
Gardoni, F.2
Marinovich, M.3
-
32
-
-
43049154803
-
Effect of cytokines on neuronal excitability
-
10.1016/j.neulet.2008.03.052. 18420346
-
Effect of cytokines on neuronal excitability. M Schafers L Sorkin, Neurosci Lett 2008 437 188 193 10.1016/j.neulet.2008.03.052 18420346
-
(2008)
Neurosci Lett
, vol.437
, pp. 188-193
-
-
Schafers, M.1
Sorkin, L.2
-
33
-
-
39049146540
-
Blunted neurogenesis and gliosis due to transgenic overexpression of human soluble IL-1ra in the mouse
-
10.1111/j.1460-9568.2008.06050.x. 18279308
-
Blunted neurogenesis and gliosis due to transgenic overexpression of human soluble IL-1ra in the mouse. S Spulber M Oprica T Bartfai B Winblad M Schultzberg, Eur J Neurosci 2008 27 549 558 10.1111/j.1460-9568.2008.06050.x 18279308
-
(2008)
Eur J Neurosci
, vol.27
, pp. 549-558
-
-
Spulber, S.1
Oprica, M.2
Bartfai, T.3
Winblad, B.4
Schultzberg, M.5
-
34
-
-
0029974018
-
Interleukin-1 mediates induction of tolerance to global ischemia in gerbil hippocampal CA1 neurons
-
10.1097/00004647-199611000-00007. 8898685
-
Interleukin-1 mediates induction of tolerance to global ischemia in gerbil hippocampal CA1 neurons. T Ohtsuki CA Ruetzler K Tasaki JM Hallenbeck, J Cereb Blood Flow Metab 1996 16 1137 1142 10.1097/00004647-199611000-00007 8898685
-
(1996)
J Cereb Blood Flow Metab
, vol.16
, pp. 1137-1142
-
-
Ohtsuki, T.1
Ruetzler, C.A.2
Tasaki, K.3
Hallenbeck, J.M.4
-
35
-
-
29744460702
-
Status epilepticus induces time-dependent neuronal and astrocytic expression of interleukin-1 receptor type i in the rat limbic system
-
10.1016/j.neuroscience.2005.07.063. 16289587
-
Status epilepticus induces time-dependent neuronal and astrocytic expression of interleukin-1 receptor type I in the rat limbic system. T Ravizza A Vezzani, Neuroscience 2006 137 301 308 10.1016/j.neuroscience.2005.07.063 16289587
-
(2006)
Neuroscience
, vol.137
, pp. 301-308
-
-
Ravizza, T.1
Vezzani, A.2
-
36
-
-
76049118058
-
Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms
-
10.1073/pnas.0911503106. 20018729
-
Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms. J Bradford JY Shin M Roberts CE Wang XJ Li S Li, Proc Natl Acad Sci USA 2009 106 22480 22485 10.1073/pnas.0911503106 20018729
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 22480-22485
-
-
Bradford, J.1
Shin, J.Y.2
Roberts, M.3
Wang, C.E.4
Li, X.J.5
Li, S.6
-
37
-
-
77951077317
-
Astrocytic expression of Parkinson's disease-related A53T alpha-synuclein causes neurodegeneration in mice
-
10.1186/1756-6606-3-12. 20409326
-
Astrocytic expression of Parkinson's disease-related A53T alpha-synuclein causes neurodegeneration in mice. XL Gu CX Long L Sun C Xie X Lin H Cai, Mol Brain 2010 3 12 10.1186/1756-6606-3-12 20409326
-
(2010)
Mol Brain
, vol.3
, pp. 12
-
-
Gu, X.L.1
Long, C.X.2
Sun, L.3
Xie, C.4
Lin, X.5
Cai, H.6
|