Cell delivery: From cell transplantation to organ engineering

Cell Transplantation

Volumn 19, Issue 6-7, 2010, Pages 655-665

  Soto Gutierrez, Alejandro ^a   Yagi, Hiroshi ^a   Uygun, Basak E ^a   Navarro Alvarez, Nalu ^b   Uygun, Korkut ^a   Kobayashi, Naoya ^c   Yang, Yong Guang ^b   Yarmush, Martin L ^a,d  

^a SHRINERS HOSPITALS FOR CHILDREN   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c OKAYAMA UNIVERSITY   (Japan)

^d RUTGERS UNIVERSITY   (United States)

Author keywords

Cell transplant; Decellularized matrices; Natural scaffolds; Organ engineering

Indexed keywords

TISSUE SCAFFOLD;

BIOENGINEERING; CELL DIFFERENTIATION; CELL HOMING; CELL POPULATION; CELL PROLIFERATION; CELL SURVIVAL; CELL THERAPY; CELL TRANSFER; CELL TRANSPLANTATION; CHRONIC LIVER DISEASE; EXTRACELLULAR MATRIX; HEPATOCYTE TRANSPLANTATION; HUMAN; LIVER FAILURE; NONHUMAN; PRIORITY JOURNAL; REVIEW; STEM CELL; STEM CELL TRANSPLANTATION; TISSUE ENGINEERING;

ANIMALS; BIOENGINEERING; CELL TRANSPLANTATION; TISSUE ENGINEERING;

EID: 77958557321     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/096368910X508753     Document Type: Review

References (66)

1. Azuma, H.; Paulk, N.; Ranade, A.; Dorrell, C.; Al-Dhalimy, M.; Ellis, E.; Strom, S.; Kay, M. A.; Finegold, M.; Grompe, M. Robust expansion of human hepatocytes in Fah-/-/Rag2-/-/Il2rg-/- mice. Nat. Biotechnol. 25(8): 903-910; 2007.
2. Badylak, S. F. The extracellular matrix as a biologic scaffold material. Biomaterials 28(25):3587-3593; 2007.
3. Badylak, S. F.; Freytes, D. O.; Gilbert, T. W. Extracellular matrix as a biological scaffold material: Structure and function. Acta Biomater. 5(1):1-13; 2009.
4. Basma, H.; Soto-Gutierrez, A.; Yannam, G. R.; Liu, L.; Ito, R.; Yamamoto, T.; Ellis, E.; Carson, S. D.; Sato, S.; Chen, Y.; Muirhead, D.; Navarro-Alvarez, N.; Wong, R. J.; Roy-Chowdhury, J.; Platt, J. L.; Mercer, D. F.; Miller, J. D.; Strom, S. C.; Kobayashi, N.; Fox, I. J. Differentiation and transplantation of human embryonic stem cell-derived hepatocytes. Gastroenterology 136(3):990-999; 2009.
5. Chan, G.; Mooney, D. J. New materials for tissue engineering: Towards greater control over the biological response. Trends Biotechnol. 26(7):382-392; 2008.
6. D'Amour, K. A.; Bang, A. G.; Eliazer, S.; Kelly, O. G.; Agulnick, A. D.; Smart, N. G.; Moorman, M. A.; Kroon, E.; Carpenter, M. K.; Baetge, E. E. Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat. Biotechnol. 24(11):1392-1401; 2006.
7. Dhawan, A.; Mitry, R. R.; Hughes, R. D.; Lehec, S.; Terry, C.; Bansal, S.; Arya, R.; Wade, J. J.; Verma, A.; Heaton, N. D.; Rela, M.; Mieli-Vergani, G. Hepatocyte transplantation for inherited factor VII deficiency. Transplantation 78(12):1812-1814; 2004.
8. Ferreira, L. S.; Gerecht, S.; Fuller, J.; Shieh, H. F.; Vunjak-Novakovic, G.; Langer, R. Bioactive hydrogel scaffolds for controllable vascular differentiation of human embryonic stem cells. Biomaterials 28(17):2706-2717; 2007.
9. Fisher, R. A.; Strom, S. C. Human hepatocyte transplantation: Worldwide results. Transplantation 82(4):441-449; 2006.
10. Fox, I. J.; Chowdhury, J. R.; Kaufman, S. S.; Goertzen, T. C.; Chowdhury, N. R.; Warkentin, P. I.; Dorko, K.; Sauter, B. V.; Strom, S. C. Treatment of the Crigler-Najjar syndrome type I with hepatocyte transplantation. N. Engl. J. Med. 338(20):1422-1426; 1998.
11. Ghosh, K.; Ingber, D. E. Micromechanical control of cell and tissue development: Implications for tissue engineering. Adv. Drug Deliv. Rev. 59(13):1306-1318; 2007.
12. Gilbert, T. W.; Sellaro, T. L.; Badylak, S. F. Decellularization of tissues and organs. Biomaterials 27(19):3675- 3683; 2006.
13. Goldman, S. A. Disease targets and strategies for the therapeutic modulation of endogenous neural stem and progenitor cells. Clin. Pharmacol. Ther. 82(4):453-460; 2007.
14. Gouon-Evans, V.; Boussemart, L.; Gadue, P.; Nierhoff, D.; Koehler, C. I.; Kubo, A.; Shafritz, D. A.; Keller, G. BMP-4 is required for hepatic specification of mouse embryonic stem cell-derived definitive endoderm. Nat. Biotechnol. 24(11):1402-1411; 2006.
15. Griffith, L. G.; Swartz, M. A. Capturing complex 3D tissue physiology in vitro. Nat. Rev. Mol. Cell Biol. 7(3): 211-224; 2006.
16. Grikscheit, T. C.; Siddique, A.; Ochoa, E. R.; Srinivasan, A.; Alsberg, E.; Hodin, R. A.; Vacanti, J. P. Tissue-engineered small intestine improves recovery after massive small bowel resection. Ann. Surg. 240(5):748-754; 2004.
17. Grossman, M.; Rader, D. J.; Muller, D. W.; Kolansky, D. M.; Kozarsky, K.; Clark, 3rd, B. J.; Stein, E. A.; Lupien, P. J.; Brewer, Jr., H. B.; Raper, S. E.; Wilson, J. M. A pilot study of ex vivo gene therapy for homozygous familial hypercholesterolaemia. Nat. Med. 1(11): 1148-1154; 1995.
18. Grossman, M.; Raper, S. E.; Kozarsky, K.; Stein, E. A.; Engelhardt, J. F.; Muller, D.; Lupien, P. J.; Wilson, J. M. Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolaemia. Nat. Genet. 6(4):335-341; 1994.
19. Guha, C.; Parashar, B.; Deb, N. J.; Garg, M.; Gorla, G. R.; Singh, A.; Roy-Chowdhury, N.; Vikram, B.; Roy-Chowdhury, J. Normal hepatocytes correct serum bilirubin after repopulation of Gunn rat liver subjected to irradiation/partial resection. Hepatology 36(2):354-362; 2002.
20. Gupta, S.; Chowdhury, J. R. Therapeutic potential of hepatocyte transplantation. Semin. Cell Dev. Biol. 13(6): 439-446; 2002.
21. Hoffman, A. S. Hydrogels for biomedical applications. Adv. Drug Deliv. Rev. 54(1):3-12; 2002.
22. Illouz, S.; Alexandre, E.; Pattenden, C.; Mark, L.; Bachellier, P.; Webb, M.; Berry, D.; Dennison, A.; Richert, L. Differential effects of curcumin on cryopreserved versus fresh primary human hepatocytes. Phytother. Res. 22(12): 1688-1691; 2008.
23. Ingber, D. E. Mechanical control of tissue growth: Function follows form. Proc. Natl. Acad. Sci. USA 102(33): 11571-11572; 2005.
24. Kawashita, Y.; Guha, C.; Moitra, R.; Wang, X.; Fox, I. J.; Roy-Chowdhury, J.; Roy-Chowdhury, N. Hepatic repopulation with stably transduced conditionally immortalized hepatocytes in the Gunn rat. J. Hepatol. 49(1):99-106; 2008.
25. Kroon, E.; Martinson, L. A.; Kadoya, K.; Bang, A. G.; Kelly, O. G.; Eliazer, S.; Young, H.; Richardson, M.; Smart, N. G.; Cunningham, J.; Agulnick, A. D.; D'Amour, K. A.; Carpenter, M. K.; Baetge, E. E. Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo. Nat. Biotechnol. 26(4):443-452; 2008.
26. Kumaran, V.; Joseph, B.; Benten, D.; Gupta, S. Integrin and extracellular matrix interactions regulate engraftment of transplanted hepatocytes in the rat liver. Gastroenterology 129(5):1643-1653; 2005.
27. Laconi, E.; Oren, R.; Mukhopadhyay, D. K.; Hurston, E.; Laconi, S.; Pani, P.; Dabeva, M. D.; Shafritz, D. A. Long-term, near-total liver replacement by transplantation of isolated hepatocytes in rats treated with retrorsine. Am. J. Pathol. 153(1):319-329; 1998.
28. Langer, R. Tissue engineering: perspectives, challenges, and future directions. Tissue Eng. 13(1):1-2; 2007.
29. Lutolf, M. P.; Hubbell, J. A. Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering. Nat. Biotechnol. 23(1):47-55; 2005.
30. Macchiarini, P.; Jungebluth, P.; Go, T.; Asnaghi, M. A.; Rees, L. E.; Cogan, T. A.; Dodson, A.; Martorell, J.; Bellini, S.; Parnigotto, P. P.; Dickinson, S. C.; Hollander, A. P.; Mantero, S.; Conconi, M. T.; Birchall, M. A. Clinical transplantation of a tissue-engineered airway. Lancet 372(9655):2023-2030; 2008.
31. Mas, V. R.; Maluf, D. G.; Thompson, M.; Ferreira-Gonzalez, A.; Fisher, R. A. Engraftment measurement in human liver tissue after liver cell transplantation by short tandem repeats analysis. Cell Transplant. 13(3):231-236; 2004.
32. Mito, K.; Ohnishi, T.; Saito, T.; Ebata, H. Hepatocellular transplantation. Gastroenterol. Jpn. 13:480-490; 1978.
33. Mitry, R. R.; Dhawan, A.; Hughes, R. D.; Bansal, S.; Lehec, S.; Terry, C.; Heaton, N. D.; Karani, J. B.; Mieli-Vergani, G.; Rela, M. One liver, three recipients: segment IV from split-liver procedures as a source of hepatocytes for cell transplantation. Transplantation 77(10):1614-1616; 2004.
34. Nagata, H.; Ito, M.; Shirota, C.; Edge, A.; McCowan, T. C.; Fox, I. J. Route of hepatocyte delivery affects hepatocyte engraftment in the spleen. Transplantation 76(4): 732-734; 2003.
35. Nagata, H.; Nishitai, R.; Shirota, C.; Zhang, J. L.; Koch, C. A.; Cai, J.; Awwad, M.; Schuurman, H. J.; Christians, U.; Abe, M.; Baranowska- Kortylewicz, J.; Platt, J. L.; Fox, I. J. Prolonged survival of porcine hepatocytes in cynomolgus monkeys. Gastroenterology 132(1):321-329; 2007.
36. Nagaya, M.; Katsuta, H.; Kaneto, H.; Bonner-Weir, S.; Weir, G. C. Adult mouse intrahepatic biliary epithelial cells induced in vitro to become insulin-producing cells. J. Endocrinol. 201(1):37-47; 2009.
37. Nahmias, Y.; Berthiaume, F.; Yarmush, M. L. Integration of technologies for hepatic tissue engineering. Adv. Biochem. Eng. Biotechnol. 103:309-329; 2007.
38. Nahmias, Y.; Schwartz, R. E.; Hu, W. S.; Verfaillie, C. M.; Odde, D. J. Endothelium-mediated hepatocyte recruitment in the establishment of liver-like tissue in vitro. Tissue Eng. 12(6):1627-1638; 2006.
39. Navarro-Alvarez, N.; Rivas-Carrillo, J. D.; Soto-Gutierrez, A.; Yuasa, T.; Okitsu, T.; Noguchi, H.; Matsumoto, S.; Takei, J.; Tanaka, N.; Kobayashi, N. Reestablishment of microenvironment is necessary to maintain in vitro and in vivo human islet function. Cell Transplant. 17(1-2): 111-119; 2008.
40. Navarro-Alvarez, N.; Soto-Gutierrez, A.; Rivas-Carrillo, E.; Chen, Y.; Yamamoto, T.; Yuasa, T.; Misawa, H.; Takei, J.; Tanaka, N.; Kobayashi, N. Self-assembling peptide nanofiber as a novel culture system for isolated porcine hepatocytes. Cell Transplant. 15(10):921-927; 2006.
41. Niklason, L. E.; Koh, J.; Solan, A. Tissue engineering of the lymphatic system. Ann. NY Acad. Sci. 979:27-34; 2002.
42. Oertel, M.; Menthena, A.; Chen, Y. Q.; Shafritz, D. A. Comparison of hepatic properties and transplantation of Thy-1(+) and Thy-1(-) cells isolated from embryonic day 14 rat fetal liver. Hepatology 46(4):1236-1245; 2007.
43. Oertel, M.; Menthena, A.; Chen, Y. Q.; Teisner, B.; Jensen, C. H.; Shafritz, D. A. Purification of fetal liver stem/progenitor cells containing all the repopulation potential for normal adult rat liver. Gastroenterology 134(3): 823-832; 2008.
44. Oertel, M.; Menthena, A.; Dabeva, M. D.; Shafritz, D. A. Cell competition leads to a high level of normal liver reconstitution by transplanted fetal liver stem/progenitor cells. Gastroenterology 130(2):507-520; 2006.
45. Ohashi, K.; Waugh, J. M.; Dake, M. D.; Yokoyama, T.; Kuge, H.; Nakajima, Y.; Yamanouchi, M.; Naka, H.; Yoshioka, A.; Kay, M. A. Liver tissue engineering at extrahepatic sites in mice as a potential new therapy for genetic liver diseases. Hepatology 41(1):132-140; 2005.
46. Ohashi, K.; Yokoyama, T.; Yamato, M.; Kuge, H.; Kanehiro, H.; Tsutsumi, M.; Amanuma, T.; Iwata, H.; Yang, J.; Okano, T.; Nakajima, Y. Engineering functional two- and three-dimensional liver systems in vivo using hepatic tissue sheets. Nat. Med. 13(7):880-885; 2007.
47. Ott, H. C.; Matthiesen, T. S.; Goh, S. K.; Black, L. D.; Kren, S. M.; Netoff, T. I.; Taylor, D. A. Perfusion-decellularized matrix: Using nature's platform to engineer a bioartificial heart. Nat. Med. 14(2):213-221; 2008.
48. Park, I. H.; Arora, N.; Huo, H.; Maherali, N.; Ahfeldt, T.; Shimamura, A.; Lensch, M. W.; Cowan, C.; Hochedlinger, K.; Daley, G. Q. Disease-specific induced pluripotent stem cells. Cell 134(5):877-886; 2008.
49. Puppi, J.; Tan, N.; Mitry, R. R.; Hughes, R. D.; Lehec, S.; Mieli-Vergani, G.; Karani, J.; Champion, M. P.; Heaton, N.; Mohamed, R.; Dhawan, A. Hepatocyte transplantation followed by auxiliary liver transplantation - a novel treatment for ornithine transcarbamylase deficiency. Am. J. Transplant. 8(2):452-457; 2008.
50. Rhim, J. A.; Sandgren, E. P.; Degen, J. L.; Palmiter, R. D.; Brinster, R. L. Replacement of diseased mouse liver by hepatic cell transplantation. Science 263(5150):1149-1152; 1994.
51. Schmeichel, K. L.; Bissell, M. J. Modeling tissue-specific signaling and organ function in three dimensions. J. Cell Sci. 116(Pt. 12):2377-2388; 2003.
52. Silva, E. A.; Mooney, D. J. Synthetic extracellular matrices for tissue engineering and regeneration. Curr. Top. Dev. Biol. 64:181-205; 2004.
53. Skuk, D.; Paradis, M.; Goulet, M.; Tremblay, J. P. Ischemic central necrosis in pockets of transplanted myoblasts in nonhuman primates: Implications for cell-transplantation strategies. Transplantation 84(10):1307-1315; 2007.
54. Soto-Gutierrez, A.; Basma, H.; Navarro-Alvarez, N.; Uygun, B.; Yarmush, M.; Kobayashi, N.; Fox, I. J. Differentiating stem cells into liver. Biotechnol. Genet. Eng. Rev. 25:149-164; 2008.
55. Soto-Gutierrez, A.; Kobayashi, N.; Rivas-Carrillo, J. D.; Navarro-Alvarez, N.; Zhao, D.; Okitsu, T.; Noguchi, H.; Basma, H.; Tabata, Y.; Chen, Y.; Tanaka, K.; Narushima, M.; Miki, A.; Ueda, T.; Jun, H. S.; Yoon, J. W.; Lebkowski, J.; Tanaka, N.; Fox, I. J. Reversal of mouse hepatic failure using an implanted liver-assist device containing ES cell-derived hepatocytes. Nat. Biotechnol. 24(11): 1412-1419; 2006.
56. Soto-Gutierrez, A.; Navarro-Alvarez, N.; Rivas-Carrillo, J. D.; Tanaka, K.; Chen, Y.; Misawa, H.; Okitsu, T.; Noguchi, H.; Tanaka, N.; Kobayashi, N. Construction and transplantation of an engineered hepatic tissue using a polyaminourethane-coated nonwoven polytetrafluoroethylene fabric. Transplantation 83(2):129-137; 2007.
57. Strom, S. C.; Chowdhury, J. R.; Fox, I. J. Hepatocyte transplantation for the treatment of human disease. Semin. Liver Dis. 19(1):39-48; 1999.
58. Strom, S. C.; Fisher, R. A.; Rubinstein, W. S.; Barranger, J. A.; Towbin, R. B.; Charron, M.; Mieles, L.; Pisarov, L. A.; Dorko, K.; Thompson, M. T.; Reyes, J. Transplantation of human hepatocytes. Transplant. Proc. 29(4): 2103-2106; 1997.
59. Tanaka, K.; Soto-Gutierrez, A.; Navarro-Alvarez, N.; Rivas-Carrillo, J. D.; Jun, H. S.; Kobayashi, N. Functional hepatocyte culture and its application to cell therapies. Cell Transplant. 15(10):855-864; 2006.
60. Wang, S.; Nagrath, D.; Chen, P. C.; Berthiaume, F.; Yarmush, M. L. Three-dimensional primary hepatocyte culture in synthetic self-assembling peptide hydrogel. Tissue Eng. Part A 14(2):227-236; 2008.
61. Wobus, A. M.; Boheler, K. R. Embryonic stem cells: Prospects for developmental biology and cell therapy. Physiol. Rev. 85(2):635-678; 2005.
62. Wu, Y. M.; Joseph, B.; Berishvili, E.; Kumaran, V.; Gupta, S. Hepatocyte transplantation and drug-induced perturbations in liver cell compartments. Hepatology 47(1):279-287; 2008.
63. Yang, Y. G.; Sykes, M. Xenotransplantation: Current status and a perspective on the future. Nat. Rev. Immunol. 7(7):519-531; 2007.
64. Yokoyama, T.; Ohashi, K.; Kuge, H.; Kanehiro, H.; Iwata, H.; Yamato, M.; Nakajima, Y. In vivo engineering of metabolically active hepatic tissues in a neovascularized subcutaneous cavity. Am. J. Transplant. 6(1):50-59; 2006.
65. Zacchigna, S.; Ruiz de Almodovar, C.; Carmeliet, P. Similarities between angiogenesis and neural development: What small animal models can tell us. Curr. Top. Dev. Biol. 80:1-55; 2008.
66. Zhang, S. Designer self-assembling Peptide nanofiber scaffolds for study of 3-d cell biology and beyond. Adv. Cancer Res. 99:335-362; 2008.