α2B-adrenoceptor deficiency leads to postnatal respiratory failure in mice

Journal of Biological Chemistry

Volumn 285, Issue 44, 2010, Pages 34213-34219

  Haubold, Miriam ^a   Gilsbach, Ralf ^a   Hein, Lutz ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENERGIC RECEPTORS; ANGIOGENESIS; BELONG TO; CELL CYCLE; CYCLIND1; IN-VITRO; IN-VIVO; LUNG MORPHOLOGY; MESENCHYMAL CELLS; MUTANT MICE; NEGATIVE FEEDBACK LOOP; RESPIRATORY FAILURE; SIGNALING PATHWAYS; SONIC HEDGEHOGS; TYPE II;

BIOLOGICAL ORGANS; ENZYME INHIBITION; FEEDBACK; MORPHOLOGY; RESPIRATORY MECHANICS; SIGNALING;

GENE EXPRESSION;

ALPHA 2B ADRENERGIC RECEPTOR; CYCLIN D1; KI 67 ANTIGEN; SONIC HEDGEHOG PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREATHING; CELL CYCLE; CELL PROLIFERATION; CONTROLLED STUDY; CYANOSIS; EMBRYO; FEEDING BEHAVIOR; GENE EXPRESSION; LUNG ALVEOLUS CELL TYPE 2; LUNG DISEASE; MESENCHYME CELL; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; RESPIRATORY FAILURE;

ANIMALS; CYCLIN D1; DISEASE MODELS, ANIMAL; EPITHELIUM; HEDGEHOG PROTEINS; HETEROZYGOTE; KI-67 ANTIGEN; LUNG; LUNG DISEASES; MESODERM; MICE; MICE, INBRED C57BL; NEUROTRANSMITTER AGENTS; RECEPTORS, ADRENERGIC, ALPHA-2; VERATRUM ALKALOIDS;

ERINACEIDAE; MUS;

EID: 77958548739     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.129205     Document Type: Article

References (30)

1. Bylund, D. B., Eikenberg, D. C., Hieble, J. P., Langer, S. Z., Lefkowitz, R. J., Minneman, K. P., Molinoff, P. B., Ruffolo, R. R., Jr., and Trendelenburg, U. (1994) Pharmacol. Rev. 46, 121-136
2. Gilsbach, R., and Hein, L. (2008) Handb. Exp. Pharmacol 184, 261-288
3. Starke, K., Endo, T., and Taube, H. D. (1975) Nature 254, 440-441
4. Starke, K., Göthert, M., and Kilbinger, H. (1989) Physiol. Rev. 69, 864-989
5. Gilsbach, R., Röser, C., Beetz, N., Brede, M., Hadamek, K., Haubold, M., Leemhuis, J., Philipp, M., Schneider, J., Urbanski, M., Szabo, B., Weinshenker, D., and Hein, L. (2009) Mol. Pharmacol. 75, 1160-1170
6. Gilsbach, R., Schneider, J., Lother, A., Schickinger, S., Leemhuis, J., and Hein, L. (2010) Cardiovasc. Res. 86, 432-442
7. Link, R. E., Desai, K., Hein, L., Stevens, M. E., Chruscinski, A., Bernstein, D., Barsh, G. S., and Kobilka, B. K. (1996) Science 273, 803-805
8. MacMillan, L. B., Hein, L., Smith, M. S., Piascik, M. T., and Limbird, L. E. (1996) Science 273, 801-803
9. Muthig, V., Gilsbach, R., Haubold, M., Philipp, M., Ivacevic, T., Gessler, M., and Hein, L. (2007) Circ. Res. 101, 682-691
10. Philipp, M., Brede, M. E., Hadamek, K., Gessler, M., Lohse, M. J., and Hein, L. (2002) Nat. Genet. 31, 311-315
11. Beetz, N., Harrison, M. D., Brede, M., Zong, X., Urbanski, M. J., Sietmann, A., Kaufling, J., Barrot, M., Seeliger, M. W., Vieira-Coelho, M. A., Hamet, P., Gaudet, D., Seda, O., Tremblay, J., Kotchen, T. A., Kaldunski, M., Nüsing, R., Szabo, B., Jacob, H. J., Cowley, A. W., Jr., Biel, M., Stoll, M., Lohse, M. J., Broeckel, U., and Hein, L. (2009) J. Clin. Invest. 119, 3597-3612
12. Boettger, T., Beetz, N., Kostin, S., Schneider, J., Krüger, M., Hein, L., and Braun, T. (2009) J. Clin. Invest. 119, 2634-2647
13. Corti, M., Brody, A. R., and Harrison, J. H. (1996) Am. J. Respir. Cell Mol. Biol. 14, 309-315
14. Gilsbach, R., Kouta, M., Bönisch, H., and Brüss, M. (2006) BioTechniques 40, 173-177
15. Beetz, N., Hein, L., Meszaros, J., Gilsbach, R., Barreto, F., Meissner, M., Hoppe, U. C., Schwartz, A., Herzig, S., and Matthes, J. (2009) Cardiovasc. Res. 84, 396-406
16. Goldsmith, E. C., Hoffman, A., Morales, M. O., Potts, J. D., Price, R. L., McFadden, A., Rice, M., and Borg, T. K. (2004) Dev. Dyn. 230, 787-794
17. Kobayashi, M., Inoue, K., Warabi, E., Minami, T., and Kodama, T. (2005) J. Atheroscler. Thromb. 12, 138-142
18. Dobbs, L. G. (1990) Am. J. Physiol. 258, L134-L147
19. Kalina, M., and Riklis, S. (1988) Histochemistry 88, 175-179
20. Chen, J. K., Taipale, J., Cooper, M. K., and Beachy, P. A. (2002) Genes Dev. 16, 2743-2748
21. Cooper, M. K., Porter, J. A., Young, K. E., and Beachy, P. A. (1998) Science 280, 1603-1607
22. Trendelenburg, A. U., Philipp, M., Meyer, A., Klebroff, W., Hein, L., and Starke, K. (2003) Naunyn Schmiedebergs Arch. Pharmacol. 368, 504-512
23. Huhtinen, A., and Scheinin, M. (2008) Eur. J. Pharmacol. 587, 48-56
24. Talke, P., Stapelfeldt, C., Lobo, E., Brown, R., Scheinin, M., and Snapir, A. (2005) Anesthesiology 102, 536-542
25. Otto, C., Hein, L., Brede, M., Jahns, R., Engelhardt, S., Gröne, H. J., and Schütz, G. (2004) Circulation 110, 3245-3251
26. Cussac, D., Schaak, S., Denis, C., Flordellis, C., Calise, D., and Paris, H. (2001) Br. J. Pharmacol. 133, 1387-1395
27. Pepicelli, C. V., Lewis, P. M., and McMahon, A. P. (1998) Curr. Biol. 8, 1083-1086
28. Chiang, C., Litingtung, Y., Lee, E., Young, K. E., Corden, J. L., Westphal, H., and Beachy, P. A. (1996) Nature 383, 407-413
29. Miller, L. A., Wert, S. E., Clark, J. C., Xu, Y., Perl, A. K., and Whitsett, J. A. (2004) Dev. Dyn. 231, 57-71
30. Bellusci, S., Furuta, Y., Rush, M. G., Henderson, R., Winnier, G., and Hogan, B. L. (1997) Development 124, 53-63