Role of histidine 932 of the human mitochondrial DNA polymerase in nucleotide discrimination and inherited disease

Journal of Biological Chemistry

Volumn 285, Issue 44, 2010, Pages 34191-34201

  Batabyal, Dipanwita ^a   McKenzie, Jessica L ^a   Johnson, Kenneth A ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HERITABLE DISORDERS; HUMAN MITOCHONDRIAL DNA POLYMERASE; INHERITED DISEASE; KINETIC EFFECT; MITOCHONDRIAL GENOMES; PROGRESSIVE ACCUMULATION;

AMINO ACIDS; CATALYSIS; DNA; GENES; MITOCHONDRIA; PHYSIOLOGY;

NUCLEOTIDES;

ALANINE; DIDEOXYNUCLEOTIDE; DNA DIRECTED DNA POLYMERASE GAMMA; HISTIDINE; HISTIDINE 932A; HISTIDINE 932Y; MITOCHONDRIAL DNA; PYROPHOSPHATE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; BASE MISPAIRING; BASE PAIRING; CATALYSIS; CONTROLLED STUDY; ENZYME KINETICS; GENE EXPRESSION; GENE FUNCTION; GENE MUTATION; HUMAN; NONHUMAN; OPHTHALMOPLEGIA; POLYMERIZATION; PRIORITY JOURNAL;

BASE PAIR MISMATCH; CATALYSIS; CLONING, MOLECULAR; DIPHOSPHATES; DNA; DNA-DIRECTED DNA POLYMERASE; GENOME, MITOCHONDRIAL; HISTIDINE; HUMANS; KINETICS; MITOCHONDRIA; MUTAGENESIS; MUTATION; NUCLEOTIDES; PARKINSON DISEASE;

EID: 77958538173     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.156182     Document Type: Article

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