The genus Sideritis: botanical and pharmacological aspects;Aspectos botánicos y farmacológicos del género Sideritis

Revista de Fitoterapia

Volumn 9, Issue 2, 2009, Pages 133-145

  Burgos, Elena González ^a   Cuadrado, M Pilar Gómez Serranillos ^a   Ruiz Poveda, Olga M Palomino ^a   Accame, M Emilia Carretero ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Essential oil; Flavonoids; Pharmacological activity; Sideritis; Terpenes

Indexed keywords

APIGENIN; CIRSIMARITIN; ESSENTIAL OIL; FLAVONE; FLAVONOID; SIDERITIS EXTRACT; TERPENE;

ANALGESIA; ANALGESIC ACTIVITY; ANGIOSPERM; ANTIINFLAMMATORY ACTIVITY; ANTIMICROBIAL ACTIVITY; CYTOTOXICITY; DRUG STRUCTURE; FLOWER; INFLAMMATION; NONHUMAN; REVIEW; SIDERITIS; SOUTHERN EUROPE; TRADITIONAL MEDICINE; ULCER;

EID: 77958532729     PISSN: 15760952     EISSN: 19885806     Source Type: Journal    
DOI: None     Document Type: Review

References (70)

1. Logoglu E, Arslan S, Öktemer A, Sakiyan I. Biological activities of some natural compounds from Sideritis sipylea Boiss. Phytother Res 2006; 20(4): 294-297.
2. Küpeli E, Sahin F, Yesilada E, Çalis I, Ezer N. In vivo anti-inflammatory and antinociceptive activity evaluation of phenolic compounds compounds from Sideritis stricta. Z Naturforsch 2007; 62(7-8): 519-525. (Pubitemid 47407714)
3. Font Quer P. Plantas Medicinales, el Dioscórides Renovado. Barcelona: Península, 1999.
4. Rios JL, Jiménez FJ, Villar A. Essential oil from Sideritis funkiana. Planta Med 1986; 52(6): 531-532.
5. Aligiannis N, Kalpoutzakis E, Chinou I.B, Mitakou S. Composition and antimicrobial activity of the essential oils of five taxa of Sideritis from Greece. J Agric Food Chem 2001; 49(2): 811-815. (Pubitemid 32172633)
6. Pardo de Santayana M, Blanco E, Morales R. Plants known as té in Spain: an ethno-pharmaco-botanical review. J Ethnopharmacol 2005; 98(1-2): 1-19.
7. Tomás-Barberán FA, Ferreres F, Tomás-Lorente F, Rivera-Nunez D, Obon-de-Castro CA chemotaxonomical study of some Portuguese Sideritis species. Biochem Systemat Ecol 1990; 18(4): 245-249.
8. Gil MI, Ferreres F, Marrero, A, Tomás-Lorente F, Tomás-Barberán FA. Distribution of flavonoid aglycones and glycosides in Sideri-tis species from the Canary Islands and Madeira. Phytochemistry 1993; 34(1): 227-232.
9. Tomás-Lorente F, Ferreres F, Tomás-Barberán FA, Rivera D, Obón C. Some flavonoids and the diterpene borjatriol from some Spanish Sideritis species. Biochem Systemat Ecol 1988; 16(1): 33-42.
10. Dewick, PM. Medicinal natural products: a biosynthetic approach. Chichester: John Wiley & Sons, 2007.
11. Palomino OM, Gomez-Serranillos P, Carretero E, Villar A. Highperformance liquid chromatography of flavonoids from Sideritis species. J Chromatogr 1996; 731(1-2): 103-108.
12. Hernández-Pérez M, Rabanal Gallego RM. Analgesic and antiinflammatory properties of Sideritis lotsyi var. Mascaensis. Phytother Res 2002; 16(3): 264-266.
13. Darias V, Bravo L, Rabanal R, Sánchez-Mateo CC, Martín-Herrera DA. Cytostatic and antibacterial activity of some compounds isolated from several Lamiaceae species from the Canary Islands. Planta Med 1990; 56(1): 70-72.
14. Topçu G, Gören A. Diterpenes from Sideritis sipylea and S. dichotoma. Turk J Chem 2002; 26(2): 189-194.
15. Ghoumari H, Benajiba M, Azmani A, García-Granados A, Martínez A, Parra A et al. Ent-kauranoid derivatives from Sideritis moorei. Phytochemistry 2005; 66(12): 1492-1498.
16. Tsaknis J, Lalas S. Extraction and identification of natural antioxidant from Sideritis euboea (Mountain Tea). J Agric Food Chem 2005; 53(16): 6375-6381.
17. Güvenç A, Houghton. PJ, Duman H., Coskun. M, Sahin. P. Antioxidant activity studies on selected Sideritis species native to Turkey. Pharmaceut Biol 2005, 43(2):173-177.
18. Laer U, Glombitza KW, Neugebauer M. The essential oil of Sideritis syriaca. Planta Med 1996; 62(1):81-82.
19. Villar A, Navarro A, Zafra-Polo MC, Rios JL. Constituents of the essential oil of Sideritis mugronensis [medicinal plant, mono -and sesquiterpenes; Spain]. Plantes Medicinales et Phytotherapie 1984; 18(3): 150-153.
20. Tomas-Barberan FA, Gil MI, Ferreres F, Rivera D, Obon C, Tomas-Lorente F. Distribution of 8-hydroxyflavone glycosides and flavonoid aglycones in some Spanish Sideritis species. Biochem Systemat Ecol 1993; 21(4): 487-497.
21. Tomas Barberan FA, Rejdali M, Harborne JB, Heywood VH. External and vacuolar flavonoids from Ibero-North African Sideritis species. A chemosystematic approach. Phytochemistry 1988; 27(1):165-170.
22. Piozzi F, Bruno M, Rosselli S, Maggio A. The diterpenoids from the genus Sideritis. En: Atta-ur-Rahman (Ed) Studies in natural products chemistry Vol 33, 493-540. Bioactive Natural Products. Elservier 2006.
23. Sahin F, Ezer N, Çalis I. Terpenic and phenolic compounds from Sideritis stricta. Turk J Chem 2006; 30:495-504.
24. Zarzuelo A. Anti-inflammatory and anti-ulcerative activity of various species of the genus Sideritis from the Alpujarra region of Spain. Fitoterapia 1993; 64: 26-30.
25. Gürbüz I, özkan AM, Yesilada E, Kutsal O. Anti-ulcerogenic activity of some plants used in folk medicine of Pinarbasi (Kayseri, Turkey). J Ethnopharmacol 2005; 101(1-3):313-318.
26. Basile A, Senatore F, Gargano R, Sorbo S, Del Pezzo M, Lavitola A, et al. Antibacterial and antioxidant activities in Sideritis italica (Miller) Greuter et Burdet essential oils. J Ethnopharmacol 2006; 107(2):240-248.
27. Alcaraz MJ, Tordera M. Studies on the gastric anti-ulcer activity of hypolaetin-8-glucoside. Phytother Res 1988; 2(2):85-88.
28. Villar A, Recio MC, Ríos JL, Zafra-Polo MC. Antimicrobial activity of essential oils from Sideritis species. Pharmazie 1986; 41(4):298-299.
29. Díaz RM, Garcia-Granados A, Moreno E, Parra A, Quevedo- Sarmiento J, Sáenz de Buruaga A et al. Studies on the relationship of structure to antimicrobial properties of diterpenoid compounds from Sideritis. Planta Med 1988; 54(4):301.
30. Rodríguez-Linde ME, Díaz RM, García-Granados A, Quevedo-Sarmiento J, Moreno E, Onorato MR, et al. Antimicrobial activity of natural and semisynthetic diterpenoids from Sideritis spp. Microbios 1994; 77(310):7-13.
31. Villar A, Jiménez MJ, Alcaraz MJ. The antiinflamatory activity of the genus Sideritis: a new insight. Plantes Medicinales et Phytotherapie 1986; 20(1):31-36.
32. Barberan FAT, Mañez S, Villar A. Identification of antiinflammatory agents from sideritis species growing in Spain. J Nat Prod 1987; 50(2):313-314.
33. Hernández-Pérez M, Rabanal RM. Evolution of the antiinflamatory and analgesic activity of Sideritis canariensis var. pannosa in mice. J Ethnopharmacol 2002; 81(1):43-47.
34. Hernández-Pérez M., Sánchez-Mateo CC, Montalbetti-Moreno Y, Rabanal RM. Studies on the analgesic and antiinflammatory effects of Sideritis candicans Ait. Var. eriocephala Webb aerial parts. J Ethnopharmacol 2004; 93(2-3):279-284.
35. Alcaraz MJ, Jiménez MJ, Valverde S, Sanz J, Rabanal RM, Villar A. Antiinflammatory compounds from Sideritis javalambrensis n-hexane extract. J Nat Prod 1989; 52(5):1088-1091.
36. Godoy A, de las Heras B, Vivas JM, Villar A. Anti-inflammatory properties of a lipid fraction obtained from Sideritis javalambrensis. Biol Pharmaceut Bull 2000; 23(10):1193-1197.
37. Villar A, Salom R, Alcaraz MJ. An approach to the antiinflammatory activity of borjatriol Planta Med 1984; 1: 90-92.
38. Alcaraz MJ, Villar A. Effect of borjatriol on the synthesis of prostaglandins. Pharmazie 1987; 42 (4): 278.
39. Villar A, Alcaraz MJ. Effect of borjatriol on nystatin oedema. Pharmazie 1984; 39(4): 278-279.
40. Villar A, Salom R, Alcaraz MJ. Effect of borjatriol on established adjuvant arthritis. Pharmazie 1983; 38(8):566
41. de las Heras B, Villar A, Vivas JM, Hoult JRS. Novel anti-inflammatory plant labdanes: Comparison of in vitro properties with aspirin and indomethacin. Inflamm Res 1994; 41(1):114-117.
42. De las Heras B, Hoult JRS. Non-cytotoxic inhibition of macrophage eicosanoid biosynthesis and effects on leukocyte functions and reactive oxygen species of two novel anti-inflammatory plant diterpenoids. Planta Med 1994; 60(6): 501-506.
43. de las Heras B, Abad MJ, Silván AM, Pascual R, Bermejo P, Rodríguez B et al. Effects of six diterpenes on macrophage eicosanoid biosynthesis. Life Sci 2001; 70(3):269-278.
44. de las Heras B, Navarro A, Díaz-Guerra MJ, Bermejo P, Castrillo A, Boscá L et al. Inhibition of NOS-2 expression in macrophages through the inactivation of NF-?B by andalusol. Brit J Pharmacol 1999; 128(3):605-612.
45. Castrillo A, de las Heras B, Hortelano S, Rodríguez B, Villar A, Boscá L. Inhibition of the nuclear factor ?B (NF-?B) pathway by tetracyclic kaurene diterpenes in macrophages. J Biol Chem 2001; 276(19):15854-15860.
46. Navarro A, de las Heras B, Villar AM. Andalusol, a diterpenoid with anti-inflammatory activity from Siderits foetens Clemen. Z Naturforsch 1997; 52(11-12):844-849.
47. Navarro A, de las Heras B, Villar AM. Anti-Inflammatory and immunomodulating properties of a sterol fraction from Sideritis foetens Clem. Biol Pharm Bull 2001; 24(5):470-473.
48. Villar A, Gasco MA, Alcaraz MJ. Anti-inflammatory and antiulcer properties of hypolaetin-8-glucoside, a novel plant flavonoid. J Pharm Pharmacol 1984; 36(12):820-823.
49. Jiménez MJ, Alcaraz MJ, Ferrandiz ML, Villar A. Anti-Inflammatory activity of a flavone from Sideritis leucantha. Planta Med 1986; 52(6):541.
50. Moroney MA, Alcaraz MJ, Forder RA, Carey F, Hoult JRS. Selectivity of neutrophil 5-lipoxygenase and cyclo-oxygenase inhibition by an anti-inflammatory flavonoid glycoside and related aglycone flavonoids. J Pharm Pharmacol 1988; 40(11):787-792.
51. Küpeli E, Sahin P, Çalis I, Yesilada E, Ezer N. Phenolic compounds of Sideritis ozturkii and their in vivo antiinflammatory and antinociceptive activities. J Ethnopharmacol 2007; 112(2):356-360. (Pubitemid 46756079)
52. Ferrándiz ML, Nair AG, Alcaraz MJ. Inhibition of sheep platelet arachidonate metabolism by flavonoids from Spanish and Indian medicinal herbs. Pharmazie 1990; 45(3):206.
53. Ferrándiz ML, Alcaraz MJ. Anti-inflammatory activity and inhibition of arachidonic acid metabolism by flavonoids. Inflamm Res 1991; 32(3):283-288.
54. Bas E, Recio MC, Giner RM, Máñez S, Cerdá- Nicolás M, Ríos JL. Anti-inflammatory activity of 5-O-demethylnobiletin, a polymethoxyflavone isolated from Sideritis tragoriganum. Planta Med 2006; 72(2):136-142.
55. Akcos Y, Ezer N, Çalis I, Demirdamar R, Tel BC. Polyphenolic compounds of Sideritis lycia and their antiinflamatory activity. Pharmaceut Biol 1999; 37(2):118-122.
56. Pinar Sahin F, Ezer N, Çalis I. Three acylated glycosides from Sideritis ozturkii Aytac & Aksoy. Phytochemistry 2004; 65(14):2095-2099.
57. Charami MT, Lazari D, Karioti A, Skaltsa H, Hadjipavlou-Litina D, Souleles C. Antioxidant and antiinflammatory activities of Sideritis perfoliata subsp. perfoliata (Lamiaceae). Phytother Res 2008; 22(4): 450-454.
58. Tunalier Z, Kosar M, Ozturk N, Baser KHC, Duman H, Kirimer N. Antioxidant properties and phenolic composition of Sideritis species. Chem Nat Comp 2004; 40(3): 206-210.
59. Sagdica O, Aksoy A, Ozkan G, Ekici L, Albayrak S. Biological activities of the extracts of two endemic Sideritis species in Turkey. Innovat Food Sci Emerg Tech 2008; 9(1): 80-84.
60. Özkan G, Sagdiç O, özcan M, özçelik H, Ünver A. Antioxidant and antibacterial activities of Turkish endemic Sideritis extracts. Grasas y Aceites 2005; 56(1):16-20.
61. Nakiboglu M, Urek RO, Kayali HA, Tarhan L. Antioxidant capacities of endemic Sideritis sipylea and Origanum sipyleum from Turkey. Food Chem 2007; 104:630-635.
62. Gabrieli CN, Kefalas PG, Kokkalou EL. Antioxidant activity of flavonoids from Sideritis raeseri. J Ethnopharmacol 2005; 96(3):423-428.
63. Rios JL, Manez S, Paya M, Alcaraz MJ. Antioxidant activity of flavonoids from Sideritis javalambrensis. Phytochemistry 1992; 31(6): 1947-1950.
64. Huguet AI, Manez S, Alcaraz M J. Superoxide scavenging properties of flavonoids in a non-enzymic system. Z Naturforsch 1990; 45:19-24.
65. Ertas A, öztürk M, Boga M, Topçu G. Antioxidant and anticholinesterase activity evaluation of ent-kaurane diterpenoids from Sideritis arguta. J Nat Prod 2009: 72(3): 500-502.
66. Bruno M, Rosselli S, Pibiri I, Kilgore N, Lee K. Anti-HIV agents derived from the ent-kaurane diterpenoid linearol. J Nat Prod 2002; 65(11): 1594-1597.
67. Bondì; M, Bruno M, Piozzi F, Husnu Can Baser K, Simmond M. Diversity and antifeedant activity of diterpenes from Turkish species of Sideritis. Biochem Syst Ecol 2000; 28(4): 299-303.
68. Loizzo MR, Tundis R, Menichini F, Saab AM, Statti GA, Menichini F. Cytotoxic activity of essential oils from labiatae and lauraceae families against in vitro human tumor models. Anticancer Res 2007; 27(5A): 3293-3299.
69. Aboutabl EA, Nassarb MI, Elsakhawy FM, Maklad YA, Osman AF, El-Khrisy EAM. Phytochemical and pharmacological studies on Sideritis taurica Stephan ex Wild. J Ethnopharmacol 2002; 82(2-3):177-184.
70. Morales R, Quintanar A, Cabezas P, Pujadas Salvá AJ (Eds.) Flora iberica Vol XII. Madrid: CSIC; 2010 en prensa.