Novel anti-Tn single-chain Fv-Fc fusion proteins derived from immunized phage library and antibody Fc domain

Anticancer Research

Volumn 30, Issue 9, 2010, Pages 3397-3405

  Kubota, Tsuguo ^a   Matsushita, Takefumi ^a   Niwa, Rinpei ^a   Kumagai, Izumi ^b   Nakamura, Kazuyasu ^a  

^a KYOWA HAKKO KOGYO CO LTD   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

Antibody dependent cellular cytotoxicity (ADCC); Fc fusion; GalNAc( 1 3) Ser Thr; Phage display; Single chain antibody; Tn antigen

Indexed keywords

HYBRID PROTEIN; IMMUNOGLOBULIN FC FRAGMENT; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; PEPTIDE LIBRARY; TN ANTIGEN; TUMOR ANTIGEN;

ANIMAL CELL; ANTIBODY SPECIFICITY; ANTIGEN BINDING; ARTICLE; CYTOTOXICITY; DNA SEQUENCE; FEMALE; IMMUNIZATION; MOUSE; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL; ANIMAL; ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; BAGG ALBINO MOUSE; CELL SEPARATION; FLOW CYTOMETRY; HUMAN; IMMUNOLOGY; JURKAT CELL LINE; PEPTIDE LIBRARY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYNTHESIS;

ANIMALS; ANTIBODY-DEPENDENT CELL CYTOTOXICITY; ANTIGENS, TUMOR-ASSOCIATED, CARBOHYDRATE; CELL SEPARATION; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNIZATION; IMMUNOGLOBULIN FC FRAGMENTS; JURKAT CELLS; MICE; MICE, INBRED BALB C; PEPTIDE LIBRARY; RECOMBINANT FUSION PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SINGLE-CHAIN ANTIBODIES;

EID: 77958524856     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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