Epothilone B confers radiation dose enhancement in DAB2IP gene knock-down radioresistant prostate cancer cells

International Journal of Radiation Oncology Biology Physics

Volumn 78, Issue 4, 2010, Pages 1210-1218

  Kong, Zhaolu ^a,b   Raghavan, Pavithra ^a   Xie, Daxing ^a   Boike, Thomas ^a   Burma, Sandeep ^a,d   Chen, David ^a,d   Chakraborty, Arup ^c   Hsieh, Jer Tsong ^a,d,e   Saha, Debabrata ^a,d  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b FUDAN UNIVERSITY   (China)

^c ROSEMAN UNIVERSITY OF HEALTH SCIENCES   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^e CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Cell cycle check points; DNA Repair; Prostate cancer; Radiosensitization

Indexed keywords

CELL CULTURE; CELL DEATH; DISEASES; DNA; DOSIMETRY; ENZYME INHIBITION; IONIZING RADIATION; REPAIR;

APOPTOSIS; CELL CYCLE; DNA REPAIR; PROSTATE CANCERS; RADIO-SENSITIZATION;

RADIOTHERAPY;

DAB2 INTERACTIVE PROTEIN; DOUBLE STRANDED DNA; EPOTHILONE B; GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; DAB2IP PROTEIN, HUMAN; EPOTHILONE DERIVATIVE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; RADIOSENSITIZING AGENT; TUMOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER RADIOTHERAPY; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CLONOGENIC ASSAY; CONTROLLED STUDY; CYTOTOXICITY; DNA REPAIR; GENE SILENCING; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; IONIZING RADIATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; RADIATION DOSE; RADIATION DOSE FRACTIONATION; RADIOSENSITIVITY; RADIOSENSITIZATION; ANIMAL; DEFICIENCY; DOUBLE STRANDED DNA BREAK; DRUG EFFECTS; DRUG SCREENING; GENETICS; MITOSIS; MULTIMODALITY CANCER THERAPY; NUDE MOUSE; PROCEDURES; PROSTATIC NEOPLASMS; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; COMBINED MODALITY THERAPY; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; EPOTHILONES; G2 PHASE; GENE KNOCKDOWN TECHNIQUES; HUMANS; MALE; MICE; MICE, NUDE; MITOSIS; NEOPLASM PROTEINS; PROSTATIC NEOPLASMS; RADIATION TOLERANCE; RADIATION-SENSITIZING AGENTS; RAS GTPASE-ACTIVATING PROTEINS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 77958510735     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2010.06.019     Document Type: Article

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