메뉴 건너뛰기




Volumn 116, Issue 22, 2010, Pages 5261-5271

The molecular pathogenesis of hereditary ovarian carcinoma

Author keywords

BRCA1; BRCA2; fallopian tube; Ki 67; ovarian cancer; p27; p53

Indexed keywords

KI 67 ANTIGEN; PROTEIN P21; PROTEIN P27; PROTEIN P53;

EID: 77958488424     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.25439     Document Type: Article
Times cited : (88)

References (40)
  • 1
    • 29144509766 scopus 로고    scopus 로고
    • BRCA1 and BRCA2 mutations account for a large proportion of ovarian carcinoma cases
    • et al.;: .
    • Pal T, Permuth-Wey J, Betts JA, et al. BRCA1 and BRCA2 mutations account for a large proportion of ovarian carcinoma cases. Cancer. 2005; 104: 2807-2816.
    • (2005) Cancer. , vol.104 , pp. 2807-2816
    • Pal, T.1    Permuth-Wey, J.2    Betts, J.A.3
  • 2
    • 0035098503 scopus 로고    scopus 로고
    • Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer
    • et al.;: .
    • Risch HA, McLaughlin JR, Cole DE, et al. Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer. Am J Hum Genet. 2001; 68: 700-710.
    • (2001) Am J Hum Genet. , vol.68 , pp. 700-710
    • Risch, H.A.1    McLaughlin, J.R.2    Cole, D.E.3
  • 3
    • 0028330276 scopus 로고
    • Risks of cancer in BRCA-1 mutation carriers. Breast Cancer Linkage Consortium
    • Ford D, Easton DF, Bishop DT, Narod SA, Goldgar DE,. Risks of cancer in BRCA-1 mutation carriers. Breast Cancer Linkage Consortium. Lancet. 1994; 343: 692-695.
    • (1994) Lancet. , vol.343 , pp. 692-695
    • Ford, D.1    Easton, D.F.2    Bishop, D.T.3    Narod, S.A.4    Goldgar, D.E.5
  • 4
    • 0142178215 scopus 로고    scopus 로고
    • Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2
    • New York Breast Cancer Study Group.;: .
    • King MC, Marks JH, Mandell JB,; New York Breast Cancer Study Group. Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2. Science. 2003; 302: 643-646.
    • (2003) Science. , vol.302 , pp. 643-646
    • King, M.C.1    Marks, J.H.2    Mandell, J.B.3
  • 5
    • 0034661872 scopus 로고    scopus 로고
    • Absence of premalignant histologic, molecular, or cell biological alterations in prophylactic oophorectomy specimens from BRCA1 heterozygotes
    • Barakat RR, Federici MG, Saigo PE, Robson ME, Offit K, Boyd J,. Absence of premalignant histologic, molecular, or cell biological alterations in prophylactic oophorectomy specimens from BRCA1 heterozygotes. Cancer. 2000; 89: 383-390.
    • (2000) Cancer. , vol.89 , pp. 383-390
    • Barakat, R.R.1    Federici, M.G.2    Saigo, P.E.3    Robson, M.E.4    Offit, K.5    Boyd, J.6
  • 6
    • 33750144168 scopus 로고    scopus 로고
    • Age-dependent morphological alterations of human ovaries from populations with and without BRCA mutations
    • et al.;: .
    • Cai KQ, Klein-Szanto A, Karthik D, et al. Age-dependent morphological alterations of human ovaries from populations with and without BRCA mutations. Gynecol Oncol. 2006; 103: 719-728.
    • (2006) Gynecol Oncol. , vol.103 , pp. 719-728
    • Cai, K.Q.1    Klein-Szanto, A.2    Karthik, D.3
  • 7
    • 0037897665 scopus 로고    scopus 로고
    • Expression of differentiation and proliferation related proteins in epithelium of prophylactically removed ovaries from women with a hereditary female adnexal cancer predisposition
    • et al.;: .
    • Piek JM, Verheijen RH, Menko FH, et al. Expression of differentiation and proliferation related proteins in epithelium of prophylactically removed ovaries from women with a hereditary female adnexal cancer predisposition. Histopathology. 2003; 43: 26-32.
    • (2003) Histopathology. , vol.43 , pp. 26-32
    • Piek, J.M.1    Verheijen, R.H.2    Menko, F.H.3
  • 8
    • 33749009287 scopus 로고    scopus 로고
    • Incidental carcinomas in prophylactic specimens in BRCA1 and BRCA2 germ-line mutation carriers, with emphasis on fallopian tube lesions: Report of 6 cases and review of the literature
    • Carcangiu ML, Peissel B, Pasini B, Spatti G, Radice P, Manoukian S,. Incidental carcinomas in prophylactic specimens in BRCA1 and BRCA2 germ-line mutation carriers, with emphasis on fallopian tube lesions: report of 6 cases and review of the literature. Am J Surg Pathol. 2006; 30: 1222-1230.
    • (2006) Am J Surg Pathol. , vol.30 , pp. 1222-1230
    • Carcangiu, M.L.1    Peissel, B.2    Pasini, B.3    Spatti, G.4    Radice, P.5    Manoukian, S.6
  • 9
    • 34548525798 scopus 로고    scopus 로고
    • Primary fallopian tube malignancies in BRCA-positive women undergoing surgery for ovarian cancer risk reduction
    • et al.;: .
    • Callahan MJ, Crum CP, Medeiros F, et al. Primary fallopian tube malignancies in BRCA-positive women undergoing surgery for ovarian cancer risk reduction. J Clin Oncol. 2007; 25: 3985-3990.
    • (2007) J Clin Oncol. , vol.25 , pp. 3985-3990
    • Callahan, M.J.1    Crum, C.P.2    Medeiros, F.3
  • 10
    • 0034810223 scopus 로고    scopus 로고
    • Occult carcinoma in prophylactic oophorectomy specimens: Prevalence and association with BRCA germline mutation status
    • Colgan TJ, Murphy J, Cole DE, Narod S, Rosen B,. Occult carcinoma in prophylactic oophorectomy specimens: prevalence and association with BRCA germline mutation status. Am J Surg Pathol. 2001; 25: 1283-1289.
    • (2001) Am J Surg Pathol. , vol.25 , pp. 1283-1289
    • Colgan, T.J.1    Murphy, J.2    Cole, D.E.3    Narod, S.4    Rosen, B.5
  • 11
    • 29144527583 scopus 로고    scopus 로고
    • Clinical and pathologic findings of prophylactic salpingo-oophorectomies in 159 BRCA1 and BRCA2 carriers
    • Finch A, Shaw P, Rosen B, Murphy J, Narod SA, Colgan TJ,. Clinical and pathologic findings of prophylactic salpingo-oophorectomies in 159 BRCA1 and BRCA2 carriers. Gynecol Oncol. 2006; 100: 58-64.
    • (2006) Gynecol Oncol. , vol.100 , pp. 58-64
    • Finch, A.1    Shaw, P.2    Rosen, B.3    Murphy, J.4    Narod, S.A.5    Colgan, T.J.6
  • 12
    • 33646816725 scopus 로고    scopus 로고
    • Predictors of occult neoplasia in women undergoing risk-reducing salpingo-oophorectomy
    • Lamb JD, Garcia RL, Goff BA, Paley PJ, Swisher EM,. Predictors of occult neoplasia in women undergoing risk-reducing salpingo-oophorectomy. Am J Obstet Gynecol. 2006; 194: 1702-1709.
    • (2006) Am J Obstet Gynecol. , vol.194 , pp. 1702-1709
    • Lamb, J.D.1    Garcia, R.L.2    Goff, B.A.3    Paley, P.J.4    Swisher, E.M.5
  • 13
    • 0036928961 scopus 로고    scopus 로고
    • Pathologic findings in prophylactic oophorectomy specimens in high-risk women
    • Leeper K, Garcia R, Swisher E, Goff B, Greer B, Paley P,. Pathologic findings in prophylactic oophorectomy specimens in high-risk women. Gynecol Oncol. 2002; 87: 52-56.
    • (2002) Gynecol Oncol. , vol.87 , pp. 52-56
    • Leeper, K.1    Garcia, R.2    Swisher, E.3    Goff, B.4    Greer, B.5    Paley, P.6
  • 14
    • 33645225423 scopus 로고    scopus 로고
    • The tubal fimbria is a preferred site for early adenocarcinoma in women with familial ovarian cancer syndrome
    • et al.;: .
    • Medeiros F, Muto MG, Lee Y, et al. The tubal fimbria is a preferred site for early adenocarcinoma in women with familial ovarian cancer syndrome. Am J Surg Pathol. 2006; 30: 230-236.
    • (2006) Am J Surg Pathol. , vol.30 , pp. 230-236
    • Medeiros, F.1    Muto, M.G.2    Lee, Y.3
  • 15
    • 16644400609 scopus 로고    scopus 로고
    • Risk-reducing salpingo-oophorectomy in BRCA mutation carriers: Role of serial sectioning in the detection of occult malignancy
    • et al.;: .
    • Powell CB, Kenley E, Chen L, et al. Risk-reducing salpingo-oophorectomy in BRCA mutation carriers: role of serial sectioning in the detection of occult malignancy. J Clin Oncol. 2005; 23: 127-132.
    • (2005) J Clin Oncol. , vol.23 , pp. 127-132
    • Powell, C.B.1    Kenley, E.2    Chen, L.3
  • 16
    • 0027960790 scopus 로고
    • Loss of heterozygosity in familial tumors from 3 BRCA1-linked kindreds
    • Neuhausen SL, Marshall CJ,. Loss of heterozygosity in familial tumors from 3 BRCA1-linked kindreds. Cancer Res. 1994; 54: 6069-6072.
    • (1994) Cancer Res. , vol.54 , pp. 6069-6072
    • Neuhausen, S.L.1    Marshall, C.J.2
  • 17
    • 0029007696 scopus 로고
    • Consistent loss of the wild type allele in breast cancers from a family linked to the BRCA2 gene on chromosome 13q12-13
    • et al.;: .
    • Collins N, McManus R, Wooster R, et al. Consistent loss of the wild type allele in breast cancers from a family linked to the BRCA2 gene on chromosome 13q12-13. Oncogene. 1995; 10: 1673-1675.
    • (1995) Oncogene. , vol.10 , pp. 1673-1675
    • Collins, N.1    McManus, R.2    Wooster, R.3
  • 18
    • 0028819984 scopus 로고
    • Different tumor types from BRCA2 carriers show wild-type chromosome deletions on 13q12-13
    • et al.;: .
    • Gudmundsson J, Johannesdottir G, Bergthorsson JT, et al. Different tumor types from BRCA2 carriers show wild-type chromosome deletions on 13q12-13. Cancer Res. 1995; 55: 4830-4832.
    • (1995) Cancer Res. , vol.55 , pp. 4830-4832
    • Gudmundsson, J.1    Johannesdottir, G.2    Bergthorsson, J.T.3
  • 19
    • 0035175430 scopus 로고    scopus 로고
    • Dysplastic changes in prophylactically removed fallopian tubes of women predisposed to developing ovarian cancer
    • et al.;: .
    • Piek JM, van Diest PJ, Zweemer RP, et al. Dysplastic changes in prophylactically removed fallopian tubes of women predisposed to developing ovarian cancer. J Pathol. 2001; 195: 451-456.
    • (2001) J Pathol. , vol.195 , pp. 451-456
    • Piek, J.M.1    Van Diest, P.J.2    Zweemer, R.P.3
  • 20
    • 0037439444 scopus 로고    scopus 로고
    • A review of p53 expression and mutation in human benign, low malignant potential, and invasive epithelial ovarian tumors
    • Kmet LM, Cook LS, Magliocco AM,. A review of p53 expression and mutation in human benign, low malignant potential, and invasive epithelial ovarian tumors. Cancer. 2003; 97: 389-404.
    • (2003) Cancer. , vol.97 , pp. 389-404
    • Kmet, L.M.1    Cook, L.S.2    Magliocco, A.M.3
  • 21
    • 0032880757 scopus 로고    scopus 로고
    • Is TP53 dysfunction required for BRCA1-associated carcinogenesis?
    • Schuijer M, Berns EM,. Is TP53 dysfunction required for BRCA1-associated carcinogenesis? Mol Cell Endocrinol. 1999; 155: 143-152.
    • (1999) Mol Cell Endocrinol. , vol.155 , pp. 143-152
    • Schuijer, M.1    Berns, E.M.2
  • 22
    • 0037219841 scopus 로고    scopus 로고
    • TP53 and ovarian cancer
    • Schuijer M, Berns EM,. TP53 and ovarian cancer. Hum Mutat. 2003; 21: 285-291.
    • (2003) Hum Mutat. , vol.21 , pp. 285-291
    • Schuijer, M.1    Berns, E.M.2
  • 23
    • 12844251290 scopus 로고    scopus 로고
    • Patterns of p53 mutations separate ovarian serous borderline tumors and low-and high-grade carcinomas and provide support for a new model of ovarian carcinogenesis
    • et al.;: .
    • Singer G, Stohr R, Cope L, et al. Patterns of p53 mutations separate ovarian serous borderline tumors and low-and high-grade carcinomas and provide support for a new model of ovarian carcinogenesis. Am J Surg Pathol. 2005; 29: 218-224.
    • (2005) Am J Surg Pathol. , vol.29 , pp. 218-224
    • Singer, G.1    Stohr, R.2    Cope, L.3
  • 24
    • 24344497920 scopus 로고    scopus 로고
    • Tumor-specific p53 sequences in blood and peritoneal fluid of women with epithelial ovarian cancer
    • et al.;: .
    • Swisher EM, Wollan M, Mahtani SM, et al. Tumor-specific p53 sequences in blood and peritoneal fluid of women with epithelial ovarian cancer. Am J Obstet Gynecol. 2005; 193: 662-667.
    • (2005) Am J Obstet Gynecol. , vol.193 , pp. 662-667
    • Swisher, E.M.1    Wollan, M.2    Mahtani, S.M.3
  • 25
    • 0034256961 scopus 로고    scopus 로고
    • P53 expression in fallopian tube carcinomas
    • et al. [letter].
    • Rosen AC, Ausch C, Klein M, et al. p53 expression in fallopian tube carcinomas [letter]. Cancer Lett. 2000; 156: 107.
    • (2000) Cancer Lett. , vol.156 , pp. 107
    • Rosen, A.C.1    Ausch, C.2    Klein, M.3
  • 26
    • 33846187651 scopus 로고    scopus 로고
    • A candidate precursor to serous carcinoma that originates in the distal fallopian tube
    • et al.;: .
    • Lee Y, Miron A, Drapkin R, et al. A candidate precursor to serous carcinoma that originates in the distal fallopian tube. J Pathol. 2007; 211: 26-35.
    • (2007) J Pathol. , vol.211 , pp. 26-35
    • Lee, Y.1    Miron, A.2    Drapkin, R.3
  • 27
    • 69549108233 scopus 로고    scopus 로고
    • Candidate serous cancer precursors in fallopian tube epithelium of BRCA1/2 mutation carriers
    • Shaw PA, Rouzbahman M, Pizer ES, Pintilie M, Begley H,. Candidate serous cancer precursors in fallopian tube epithelium of BRCA1/2 mutation carriers. Mod Pathol. 2009; 22: 1133-1138.
    • (2009) Mod Pathol. , vol.22 , pp. 1133-1138
    • Shaw, P.A.1    Rouzbahman, M.2    Pizer, E.S.3    Pintilie, M.4    Begley, H.5
  • 28
    • 42949138321 scopus 로고    scopus 로고
    • A candidate precursor to pelvic serous cancer (p53 signature) and its prevalence in ovaries and fallopian tubes from women with BRCA mutations
    • Folkins AK, Jarboe EA, Saleemuddin A,. A candidate precursor to pelvic serous cancer (p53 signature) and its prevalence in ovaries and fallopian tubes from women with BRCA mutations. Gynecol Oncol. 2008; 109: 168-173.
    • (2008) Gynecol Oncol. , vol.109 , pp. 168-173
    • Folkins, A.K.1    Jarboe, E.A.2    Saleemuddin, A.3
  • 29
    • 33846185401 scopus 로고    scopus 로고
    • The distal fallopian tube: A new model for pelvic serous carcinogenesis
    • et al.;: .
    • Crum CP, Drapkin R, Miron A, et al. The distal fallopian tube: a new model for pelvic serous carcinogenesis. Curr Opin Obstet Gynecol. 2007; 19: 3-9.
    • (2007) Curr Opin Obstet Gynecol. , vol.19 , pp. 3-9
    • Crum, C.P.1    Drapkin, R.2    Miron, A.3
  • 30
    • 33846624310 scopus 로고    scopus 로고
    • Intraepithelial carcinoma of the fimbria and pelvic serous carcinoma: Evidence for a causal relationship
    • et al.;: .
    • Kindelberger DW, Lee Y, Miron A, et al. Intraepithelial carcinoma of the fimbria and pelvic serous carcinoma: evidence for a causal relationship. Am J Surg Pathol. 2007; 31: 161-169.
    • (2007) Am J Surg Pathol. , vol.31 , pp. 161-169
    • Kindelberger, D.W.1    Lee, Y.2    Miron, A.3
  • 31
    • 0033984235 scopus 로고    scopus 로고
    • The Ki-67 protein: From the known and the unknown
    • Scholzen T, Gerdes J,. The Ki-67 protein: from the known and the unknown. J Cell Physiol. 2000; 182: 311-322.
    • (2000) J Cell Physiol. , vol.182 , pp. 311-322
    • Scholzen, T.1    Gerdes, J.2
  • 32
    • 0035479017 scopus 로고    scopus 로고
    • BRCA1-associated tumorigenesis: What have we learned from knockout mice?
    • Brodie SG, Deng CX,. BRCA1-associated tumorigenesis: what have we learned from knockout mice? Trends Genet. 2001; 17: S18-22.
    • (2001) Trends Genet. , vol.17 , pp. 18-22
    • Brodie, S.G.1    Deng, C.X.2
  • 33
    • 0033564697 scopus 로고    scopus 로고
    • CDK inhibitors: Positive and negative regulators of G1-phase progression
    • Sherr DJ, Roberts JM,. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev. 1999; 13: 1501-1512.
    • (1999) Genes Dev. , vol.13 , pp. 1501-1512
    • Sherr, D.J.1    Roberts, J.M.2
  • 34
    • 0037046491 scopus 로고    scopus 로고
    • BRCA1 transactivates the cyclin-dependent kinase inhibitor p27 (Kip1)
    • Williamson EA, Dadmanesh F, Koeffler HP,. BRCA1 transactivates the cyclin-dependent kinase inhibitor p27 (Kip1). Oncogene. 2002; 21: 3199-3206.
    • (2002) Oncogene. , vol.21 , pp. 3199-3206
    • Williamson, E.A.1    Dadmanesh, F.2    Koeffler, H.P.3
  • 36
    • 0034671186 scopus 로고    scopus 로고
    • Kip1 protein levels independently predict outcome after breast cancer
    • et al.;: .
    • Kip1 protein levels independently predict outcome after breast cancer. J Clin Oncol. 2000; 18: 4045-4052.
    • (2000) J Clin Oncol. , vol.18 , pp. 4045-4052
    • Chappuis, P.O.1    Kapusta, L.2    Begin, L.R.3
  • 37
    • 20144387584 scopus 로고    scopus 로고
    • Phenotypic characterization of BRCA1 and BRCA2 tumors based in a tissue microarray study with 37 immunohistochemical markers
    • et al.;: .
    • Palacios J, Honrado E, Osorio A, et al. Phenotypic characterization of BRCA1 and BRCA2 tumors based in a tissue microarray study with 37 immunohistochemical markers. Breast Cancer Res Treat. 2005; 90: 5-14.
    • (2005) Breast Cancer Res Treat. , vol.90 , pp. 5-14
    • Palacios, J.1    Honrado, E.2    Osorio, A.3
  • 38
    • 3242775263 scopus 로고    scopus 로고
    • Follow-up of in situ and early stage fallopian tube carcinoma in patients undergoing prophylactic surgery for proven or suspected BRCA-1 or BRCA-2 mutations
    • Agoff SN, Garcia RL, Goff BA, Swisher EM,. Follow-up of in situ and early stage fallopian tube carcinoma in patients undergoing prophylactic surgery for proven or suspected BRCA-1 or BRCA-2 mutations. Am J Surg Pathol. 2004; 28: 1112-1114.
    • (2004) Am J Surg Pathol. , vol.28 , pp. 1112-1114
    • Agoff, S.N.1    Garcia, R.L.2    Goff, B.A.3    Swisher, E.M.4
  • 39
    • 60549088557 scopus 로고    scopus 로고
    • Altered proliferation and differentiation properties of primary mammary epithelial cells from BRCA1 mutation carriers
    • et al.;: .
    • Burga LN, Tung NM, Troyan SL, et al. Altered proliferation and differentiation properties of primary mammary epithelial cells from BRCA1 mutation carriers. Cancer Res. 2009; 69: 1273-1278.
    • (2009) Cancer Res. , vol.69 , pp. 1273-1278
    • Burga, L.N.1    Tung, N.M.2    Troyan, S.L.3
  • 40
    • 55649115101 scopus 로고    scopus 로고
    • Risk factors for a serous cancer precursor ("p53 signature") in women with inherited BRCA mutations
    • et al.;: .
    • Saleemuddin A, Folkins AK, Garrett L, et al. Risk factors for a serous cancer precursor ("p53 signature") in women with inherited BRCA mutations. Gynecol Oncol. 2008; 111: 226-232.
    • (2008) Gynecol Oncol. , vol.111 , pp. 226-232
    • Saleemuddin, A.1    Folkins, A.K.2    Garrett, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.