Tail-mediated collapse of HMGB1 is dynamic and occurs via differential binding of the acidic tail to the A and B domains

Journal of Molecular Biology

Volumn 403, Issue 5, 2010, Pages 706-722

  Stott, Katherine ^a   Watson, Matthew ^a   Howe, Françoise S ^a   Grossmann, J Günter ^a   Thomas, Jean O ^a,b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b SCIENCE AND TECHNOLOGY FACILITIES COUNCIL   (United Kingdom)

Author keywords

Acidic tail; Ensemble optimization method (EOM); NMR spectroscopy; Paramagnetic relaxation enhancement (PRE); Small angle X ray scattering (SAXS)

Indexed keywords

(1 OXYL 2,2,5,5 TETRAMETHYL 3 PYRROLIDIN 3 YL)METHYL METHANETHIOSULFONATE; HIGH MOBILITY GROUP B1 PROTEIN; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; GEL FILTRATION; MOLECULAR DYNAMICS; NITROGEN NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; X RAY CRYSTALLOGRAPHY;

EID: 77958472027     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2010.07.045     Document Type: Article

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