Extended Safety Data for the Oral Cavity Probiotic Streptococcus salivarius K12

Probiotics and Antimicrobial Proteins

Volumn 2, Issue 3, 2010, Pages 135-144

  Burton, J P ^a   Chilcott, C N ^a   Wescombe, P A ^a   Tagg, J R ^b  

^a BLIS Technologies Ltd   (New Zealand)

^b UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Bacteriocins; BLIS; Probiotics; Safety; Streptococcus salivarius

Indexed keywords

BACTERIOCIN; PROBIOTIC AGENT;

ACUTE TOXICITY; ARTICLE; BACTERIAL MUTATION; BIOCHEMISTRY; BODY WEIGHT; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG SAFETY; FEMALE; GENOTOXICITY; HEMATOLOGY; HISTOPATHOLOGY; HUMAN; LOZENGE; MALE; MORNING DOSAGE; MUTAGENICITY; NONHUMAN; ORGAN WEIGHT; PHENOTYPE; PRESCHOOL CHILD; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RAT; REVERTANT; SCHOOL CHILD; SCORING SYSTEM; STREPTOCOCCUS SALIVARIUS; URINALYSIS;

BACTERIA (MICROORGANISMS); RATTUS; STREPTOCOCCUS SALIVARIUS;

EID: 77958456141     PISSN: 18671306     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12602-010-9045-4     Document Type: Article

References (30)

1. Abdelgadir WS, Hamad SH, Jakobsen MPLM (2001) Characterisation of the dominant microbiota of Sudanese fermented milk Rob. International Dairy Journal 11: 63-70.
2. Bentley RW, Leigh JA, Collins MD (1991) Intrageneric structure of Streptococcus based on comparative analysis of small-subunit rRNA sequences. Int J Syst Bacteriol 41: 487-494.
3. Bishop CJ, Aanensen DM, Jordan GE, Kilian M, Hanage WP, Spratt BG (2009) Assigning strains to bacterial species via the internet. BMC Biol 7: 3.
4. Burton JP, Wescombe PA, Moore CJ, Chilcott CN, Tagg JR (2006) Safety assessment of the oral cavity probiotic Streptococcus salivarius K12. Appl Environ Microbiol 72: 3050-3053.
5. Callon C, Millet L, Montel MC (2004) Diversity of lactic acid bacteria isolated from AOC Salers cheese. J Dairy Res 71: 231-244.
6. Carlsson J, Grahnen H, Jonsson G, Wikner S (1970) Early establishment of Streptococcus salivarius in the mouth of infants. J Dent Res 49: 415-418.
7. Cosseau C, Devine DA, Dullaghan E, Gardy JL, Chikatamarla A, Gellatly S, Yu LL, Pistolic J, Falsafi R, Tagg J, Hancock RE (2008) The commensal Streptococcus salivarius K12 downregulates the innate immune responses of human epithelial cells and promotes host-microbe homeostasis. Infect Immun 76: 4163-4175.
8. Devine DA, Pistolic J, Abouserwel A, Saha S, Percival R, Hancock EM (2009) Presented at the IADR, Miami, Florida, USA.
9. Dierksen KP, Tagg J (2000) The influence of indigenous bacteriocin-producing Streptococcus salivarius on the acquisition of Streptococcus pyogenes by primary school children in Dunedin, New Zealand. In: Martin DRTJ (ed) Streptococci and streptococcal diseases entering the new millennium. Securacopy, Auckland, pp 81-85.
10. EPA posting date. EPA Health Effects Test Guidelines OPPTs 870. 5100 Bacteria Reverse Mutation Test. [Online.].
11. Farrow JA, Collins MD (1984) DNA base composition, DNA-DNA homology and long-chain fatty acid studies on Streptococcus thermophilus and Streptococcus salivarius. J Gen Microbiol 130: 357-362.
12. FDA/CFSAN (2003) Bacterial reverse mutation test. In: Toxicological principles for the safety assessment of food ingredients, FDA/CFSAN Office of Food Additive Safety Redbook 2000: IV. C. 1. a.
13. Heikkila MP, Saris PE (2003) Inhibition of Staphylococcus aureus by the commensal bacteria of human milk. J Appl Microbiol 95: 471-478.
14. Hillman JD, McDonell E, Hillman CH, Zahradnik RT, Soni MG (2009) Safety assessment of ProBiora3, a probiotic mouthwash: subchronic toxicity study in rats. Int J Toxicol 28: 357-367.
15. Hyink O, Wescombe PA, Upton M, Ragland N, Burton JP, Tagg JR (2007) Salivaricin A2 and the novel lantibiotic salivaricin B are encoded at adjacent loci on a 190-kilobase transmissible megaplasmid in the oral probiotic strain Streptococcus salivarius K12. Appl Environ Microbiol 73: 1107-1113.
16. Innings A, Krabbe M, Ullberg M, Herrmann B (2005) Identification of 43 Streptococcus species by pyrosequencing analysis of the rnpB gene. J Clin Microbiol 43: 5983-5991.
17. Kurwijila L (2005) Technologies for enhancing value addition, quality and safety of milk produced by smallholder farmers in Africa. In: Proceedings of the 4th AACAA and 31st TSAP Annual Meeting.
18. Marti{dotless}n R, Langa S, Reviriego C, Marin ML, Olivares M, Boza J, Jimenez L, Fernandez J, Xaus J, Rodriguez JM (2004) The commensal microflora of human milk: new perspectives for food bacteriotherapy and probiotics. Trends Food Sci Technol 15: 121-127.
19. Mogensen G, Salminen S, O'Brien J, Ouwehand A, Holzapfel W, Shortt C, Fonden R, Miller GD, Donohue D, Playne M, Crittenden R, Bianchi Salvadori B, Zink R (2002) Health benefits and safety evaluation of certain food components. Food microorganisms-health benefits, safety evaluation and strains with documented history of use in foods. Int Dairy Federation (IDF) 4-20.
20. Mora D, Ricci G, Guglielmetti S, Daffonchio D, Fortina MG (2003) 16S-23S rRNA intergenic spacer region sequence variation in Streptococcus thermophilus and related dairy streptococci and development of a multiplex ITS-SSCP analysis for their identification. Microbiology 149: 807-813.
21. Obodai M, Dodd CE (2006) Characterization of dominant microbiota of a Ghanaian fermented milk product, nyarmie, by culture- and nonculture-based methods. J Appl Microbiol 100: 1355-1363.
22. OECD (1997) OECD guideline for the testing of chemicals (471): Bacterial Reverse Mutation Test.
23. Ongol MP, Asano K (2009) Main microorganisms involved in the fermentation of Ugandan ghee. Int J Food Microbiol.
24. Pesic-Mikulec D (2005) Microbiological study of fresh white cheese applied ecology and environmental research. 4: 129-134.
25. Riani C (2009) Effects of oral streptococci and selected probiotic bacteria on the pathogen Streptococcus pyogenes: viability, biofilms, molecular functions, and virulence traits. der Univesitat Rostock, Rostock.
26. Tagg J, Burton JP, Wescombe P, Chilcott C (2008) Streptococci as effector organisms for probiotic and replacement therapy. In: Versalovic J, Wilson M (eds) Therapeutic microbiology: probiotic and related strategies. American Society for Microbiology, USA.
27. Tagg JR, Bannister LV (1979) "Fingerprinting" beta-haemolytic streptococci by their production of and sensitivity to bacteriocine-like inhibitors. J Med Microbiol 12: 397-411.
28. van Hoorde K, Verstraete T, Vandamme P, Huys G (2008) Diversity of lactic acid bacteria in two Flemish artisan raw milk Gouda-type cheeses. Food Microbiol 25: 929-935.
29. Wescombe PA, Heng NC, Burton JP, Chilcott CN, Tagg JR (2009) Streptococcal bacteriocins and the case for Streptococcus salivarius as model oral probiotics. Future Microbiol 4: 819-835.
30. WHO (2002) Guidelines for the evaluation of probiotics in food. Food and Agriculture Organization of the United Nations, World Health Organisation, Geneva.