-
1
-
-
0032958470
-
Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats
-
DOI 10.1038/5013
-
TJ Aitman AM Glazier CA Wallace LD Cooper PJ Norsworthy FN Wahid KM Al-Majali PM Trembling CJ Mann CC Shoulders D Graf E St Lezin TW Kurtz V Kren M Pravenec A Ibrahimi NA Abumrad LW Stanton J Scott 1999 Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats Nat Genet 21 76 83 10.1038/5013 9916795 (Pubitemid 29036288)
-
(1999)
Nature Genetics
, vol.21
, Issue.1
, pp. 76-83
-
-
Aitman, T.J.1
Glazier, A.M.2
Wallace, C.A.3
Cooper, L.D.4
Norsworthy, P.J.5
Wahid, F.N.6
Al-Majali, K.M.7
Trembling, P.M.8
Mann, C.J.9
Shoulders, C.C.10
Graf, D.11
St. Lezin, E.12
Kurtz, T.W.13
Kren, V.14
Pravenec, M.15
Ibrahimi, A.16
Abumrad, N.A.17
Stanton, L.W.18
Scott, J.19
-
2
-
-
36348940009
-
Intestinal monoacylglycerol metabolism: Developmental and nutritional regulation of monoacylglycerol lipase and monoacylglycerol acyltransferase
-
DOI 10.1074/jbc.M706994200
-
SH Chon YX Zhou JL Dixon J Storch 2007 Intestinal monoacylglycerol metabolism: developmental and nutritional regulation of monoacylglycerol lipase and monoacylglycerol acyltransferase J Biol Chem 282 33346 33357 10.1074/jbc.M706994200 17848545 (Pubitemid 350159529)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.46
, pp. 33346-33357
-
-
Chon, S.-H.1
Yin, X.Z.2
Dixon, J.L.3
Storch, J.4
-
3
-
-
0348111308
-
Expression of the Insulin-responsive Glucose Transporter GLUT4 in Adipocytes Is Dependent on Liver X Receptor α
-
DOI 10.1074/jbc.M302287200
-
KT Dalen SM Ulven K Bamberg JA Gustafsson HI Nebb 2003 Expression of the insulin-responsive glucose transporter GLUT4 in adipocytes is dependent on liver X receptor alpha J Biol Chem 278 48283 48291 10.1074/jbc.M302287200 12970362 (Pubitemid 37526713)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.48
, pp. 48283-48291
-
-
Dalen, K.T.1
Ulven, S.M.2
Bamberg, K.3
Gustafsson, J.-A.4
Nebb, H.I.5
-
4
-
-
0036079637
-
Increased hepatic lipogenesis but decreased expression of lipogenic gene in adipose tissue in human obesity
-
11739082
-
F Diraison E Dusserre H Vidal M Sothier M Beylot 2002 Increased hepatic lipogenesis but decreased expression of lipogenic gene in adipose tissue in human obesity Am J Physiol Endocrinol Metab 282 E46 E51 11739082
-
(2002)
Am J Physiol Endocrinol Metab
, vol.282
-
-
Diraison, F.1
Dusserre, E.2
Vidal, H.3
Sothier, M.4
Beylot, M.5
-
5
-
-
26044482425
-
Phosphatidylinositol 3-kinase is required for the transcriptional activation of cyclin D2 in BCR activated primary mouse B lymphocytes
-
DOI 10.1002/eji.200425812
-
J Glassford E Vigorito I Soeiro PA Madureira G Zoumpoulidou JJ Brosens M Turner EW Lam 2005 Phosphatidylinositol 3-kinase is required for the transcriptional activation of cyclin D2 in BCR activated primary mouse B lymphocytes Eur J Immunol 35 2748 2761 10.1002/eji.200425812 16114097 (Pubitemid 41404058)
-
(2005)
European Journal of Immunology
, vol.35
, Issue.9
, pp. 2748-2761
-
-
Glassford, J.1
Vigorito, E.2
Soeiro, I.3
Madureira, P.A.4
Zoumpoulidou, G.5
Brosens, J.J.6
Turner, M.7
Lam, E.W.-F.8
-
6
-
-
40849101548
-
Subtle changes in peptide conformation profoundly affect recognition of the non-classical MHC class i molecule HLA-E by the CD94-NKG2 natural killer cell receptors
-
10.1016/j.jmb.2008.01.098 18339401
-
HL Hoare LC Sullivan CS Clements LK Ely T Beddoe KN Henderson J Lin HH Reid AG Brooks J Rossjohn 2008 Subtle changes in peptide conformation profoundly affect recognition of the non-classical MHC class I molecule HLA-E by the CD94-NKG2 natural killer cell receptors J Mol Biol 377 1297 1303 10.1016/j.jmb.2008.01.098 18339401
-
(2008)
J Mol Biol
, vol.377
, pp. 1297-1303
-
-
Hoare, H.L.1
Sullivan, L.C.2
Clements, C.S.3
Ely, L.K.4
Beddoe, T.5
Henderson, K.N.6
Lin, J.7
Reid, H.H.8
Brooks, A.G.9
Rossjohn, J.10
-
7
-
-
0037471351
-
Rhythmic, reciprocal ghrelin and leptin signaling: New insight in the development of obesity
-
DOI 10.1016/S0167-0115(02)00305-1
-
SP Kalra M Bagnasco EE Otukonyong MG Dube PS Kalra 2003 Rhythmic, reciprocal ghrelin and leptin signaling: new insight in the development of obesity Regul Pept 111 1 11 10.1016/S0167-0115(02)00305-1 12609743 (Pubitemid 36254743)
-
(2003)
Regulatory Peptides
, vol.111
, Issue.1-3
, pp. 1-11
-
-
Kalra, S.P.1
Bagnasco, M.2
Otukonyong, E.E.3
Dube, M.G.4
Kalra, P.S.5
-
8
-
-
6344281175
-
Association of the gene encoding wingless-type mammary tumor virus integration-site family member 5B (WNT5B) with type 2 diabetes
-
DOI 10.1086/425340
-
A Kanazawa S Tsukada A Sekine T Tsunoda A Takahashi A Kashiwagi Y Tanaka T Babazono M Matsuda K Kaku Y Iwamoto R Kawamori R Kikkawa Y Nakamura S Maeda 2004 Association of the gene encoding wingless-type mammary tumor virus integration-site family member 5B (WNT5B) with type 2 diabetes Am J Hum Genet 75 832 843 10.1086/425340 15386214 (Pubitemid 39390490)
-
(2004)
American Journal of Human Genetics
, vol.75
, Issue.5
, pp. 832-843
-
-
Kanazawa, A.1
Tsukada, S.2
Sekine, A.3
Tsunoda, T.4
Takahashi, A.5
Kashiwagi, A.6
Tanaka, Y.7
Babazono, T.8
Matsuda, M.9
Kaku, K.10
Iwamoto, Y.11
Kawamori, R.12
Kikkawa, R.13
Nakamura, Y.14
Maeda, S.15
-
9
-
-
25144482784
-
Type 2 diabetes mouse model TallyHo carries an obesity gene on chromosome 6 that exaggerates dietary obesity
-
DOI 10.1152/physiolgenomics.00197.2004
-
JH Kim TP Stewart W Zhang HY Kim PM Nishina JK Naggert 2005 Type 2 diabetes mouse model TallyHo carries an obesity gene on chromosome 6 that exaggerates dietary obesity Physiol Genomics 22 171 181 10.1152/physiolgenomics. 00197.2004 15870394 (Pubitemid 41356350)
-
(2005)
Physiological Genomics
, vol.22
, pp. 171-181
-
-
Kim, J.H.1
Stewart, T.P.2
Zhang, W.3
Kim, H.Y.4
Nishina, P.M.5
Naggert, J.K.6
-
10
-
-
33646928066
-
Changes in gene expression foreshadow diet-induced obesity in genetically identical mice
-
DOI 10.1371/journal.pgen.0020081
-
RA Koza L Nikonova J Hogan JS Rim T Mendoza C Faulk J Skaf LP Kozak 2006 Changes in gene expression foreshadow diet-induced obesity in genetically identical mice PLoS Genet 2 e81 10.1371/journal.pgen.0020081 16733553 (Pubitemid 43794325)
-
(2006)
PLoS Genetics
, vol.2
, Issue.5
, pp. 769-780
-
-
Koza, R.A.1
Nikonova, L.2
Hogan, J.3
Rim, J.-S.4
Mendoza, T.5
Faulk, C.6
Skaf, J.7
Kozak, L.P.8
-
11
-
-
4744348346
-
Medical consequences of obesity
-
DOI 10.1016/j.clindermatol.2004.01.012, PII S0738081X04000136
-
VJ Lawrence PG Kopelman 2004 Medical consequences of obesity Clin Dermatol 22 296 302 10.1016/j.clindermatol.2004.01.012 15475229 (Pubitemid 39314614)
-
(2004)
Clinics in Dermatology
, vol.22
, pp. 296-302
-
-
Lawrence, V.J.1
Kopelman, P.G.2
-
12
-
-
0027526303
-
cDNA cloning of a human mRNA preferentially expressed in hematopoietic cells and with homology to a GDP-dissociation inhibitor for the rho GTP- binding proteins
-
DOI 10.1073/pnas.90.4.1479
-
JM Lelias CN Adra GM Wulf JC Guillemot M Khagad D Caput B Lim 1993 cDNA cloning of a human mRNA preferentially expressed in hematopoietic cells and with homology to a GDP-dissociation inhibitor for the rho GTP-binding proteins Proc Natl Acad Sci USA 90 1479 1483 10.1073/pnas.90.4.1479 8434008 (Pubitemid 23058196)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.4
, pp. 1479-1483
-
-
Lelias, J.-M.1
Adra, C.N.2
Wulf, G.M.3
Guillemot, J.-C.4
Khagad, M.5
Caput, D.6
Lim, B.7
-
13
-
-
0035710746
-
-ΔΔCT method
-
DOI 10.1006/meth.2001.1262
-
KJ Livak TD Schmittgen 2001 Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method Methods 25 402 408 10.1006/meth.2001.1262 11846609 (Pubitemid 34164012)
-
(2001)
Methods
, vol.25
, Issue.4
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
14
-
-
0034714382
-
Molecular characterization of human acetyl-CoA synthetase, an enzyme regulated by sterol regulatory element-binding proteins
-
10.1074/jbc.M004160200 10843999
-
A Luong VC Hannah MS Brown JL Goldstein 2000 Molecular characterization of human acetyl-CoA synthetase, an enzyme regulated by sterol regulatory element-binding proteins J Biol Chem 275 26458 26466 10.1074/jbc.M004160200 10843999
-
(2000)
J Biol Chem
, vol.275
, pp. 26458-26466
-
-
Luong, A.1
Hannah, V.C.2
Brown, M.S.3
Goldstein, J.L.4
-
15
-
-
0034729710
-
Gigantism in mice lacking suppressor of cytokine signalling-2
-
DOI 10.1038/35016611
-
D Metcalf CJ Greenhalgh E Viney TA Willson R Starr NA Nicola DJ Hilton WS Alexander 2000 Gigantism in mice lacking suppressor of cytokine signalling-2 Nature 405 1069 1073 10.1038/35016611 10890450 (Pubitemid 30447793)
-
(2000)
Nature
, vol.405
, Issue.6790
, pp. 1069-1073
-
-
Metcalf, D.1
Greenhalgh, C.J.2
Viney, E.3
Wilison, T.A.4
Starr, R.5
Nicola, N.A.6
Hilton, D.J.7
Alexander, W.S.8
-
16
-
-
0021153791
-
Secretory rhythm of growth hormone regulates sexual differentiation of mouse liver
-
10.1016/0092-8674(84)90030-8 6323022
-
G Norstedt R Palmiter 1984 Secretory rhythm of growth hormone regulates sexual differentiation of mouse liver Cell 36 805 812 10.1016/0092-8674(84) 90030-8 6323022
-
(1984)
Cell
, vol.36
, pp. 805-812
-
-
Norstedt, G.1
Palmiter, R.2
-
17
-
-
73949146174
-
The gene expression of the main lipogenic enzymes is downregulated in visceral adipose tissue of obese subjects
-
doi: 10.1088/oby.2009.202
-
Ortega FJ, Mayas D, Moreno-Navarrete JM, Catalán V, Gómez-Ambrosi J, Esteve E, Rodriguez-Hermosa JI, Ruiz B, Ricart W, Peral B, Fruhbeck G, Tinahones FJ, Fernández-Real JM (2009) The gene expression of the main lipogenic enzymes is downregulated in visceral adipose tissue of obese subjects. Obesity (Silver Spring). doi: 10.1088/oby.2009.202
-
(2009)
Obesity (Silver Spring).
-
-
Ortega Fj, M.1
-
18
-
-
36849010732
-
Wnt/β-catenin signaling in adipogenesis and metabolism
-
DOI 10.1016/j.ceb.2007.09.014, PII S0955067407001378, Cell Differentiation / Cell Division, Growth and Death
-
TC Prestwich OA Macdougald 2007 Wnt/beta-catenin signaling in adipogenesis and metabolism Curr Opin Cell Biol 19 612 617 10.1016/j.ceb.2007. 09.014 17997088 (Pubitemid 350225661)
-
(2007)
Current Opinion in Cell Biology
, vol.19
, Issue.6
, pp. 612-617
-
-
Prestwich, T.C.1
MacDougald, O.A.2
-
19
-
-
0038651062
-
Differential expression of growth factors at the cellular level in virus-infected brain
-
DOI 10.1073/pnas.0430999100
-
M Prosniak A Zborek GS Scott A Roy TW Phares H Koprowski DC Hooper 2003 Differential expression of growth factors at the cellular level in virus-infected brain Proc Natl Acad Sci USA 100 6765 6770 10.1073/pnas. 0430999100 12736376 (Pubitemid 36666654)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.11
, pp. 6765-6770
-
-
Prosniak, M.1
Zborek, A.2
Scott, G.S.3
Roy, A.4
Phares, T.W.5
Koprowski, H.6
Hooper, D.C.7
-
20
-
-
34247352502
-
Myocardium defects and ventricular hypoplasia in mice homozygous null for the Forkhead Box M1 transcription factor
-
DOI 10.1002/dvdy.21113
-
S Ramakrishna IM Kim V Petrovic D Malin IC Wang TV Kalin L Meliton YY Zhao T Ackerson Y Qin AB Malik RH Costa VV Kalinichenko 2007 Myocardium defects and ventricular hypoplasia in mice homozygous null for the Forkhead Box M1 transcription factor Dev Dyn 236 1000 1013 10.1002/dvdy.21113 17366632 (Pubitemid 46641341)
-
(2007)
Developmental Dynamics
, vol.236
, Issue.4
, pp. 1000-1013
-
-
Ksmiakrishna, S.1
Kim, I.-M.2
Petrovic, V.3
Malin, D.4
Wang, I.-C.5
Kalin, T.V.6
Meliton, L.7
Zhao, Y.-Y.8
Ackerson, T.9
Qin, Y.10
Malik, A.B.11
Costa, R.H.12
Kalinichenko, V.V.13
-
21
-
-
0029000265
-
Detection and positional cloning of blood pressure quantitative trait loci: Is it possible?
-
7768551
-
JP Rapp AY Deng 1995 Detection and positional cloning of blood pressure quantitative trait loci: is it possible? Hypertension 25 1121 1128 7768551
-
(1995)
Hypertension
, vol.25
, pp. 1121-1128
-
-
Rapp, J.P.1
Deng, A.Y.2
-
22
-
-
0037433040
-
Identifying differentially expressed genes using false discovery rate controlling procedures
-
DOI 10.1093/bioinformatics/btf877
-
A Reiner D Yekutieli Y Benjamini 2003 Identifying differentially expressed genes using false discovery rate controlling procedures Bioinformatics 19 368 375 10.1093/bioinformatics/btf877 12584122 (Pubitemid 36284936)
-
(2003)
Bioinformatics
, vol.19
, Issue.3
, pp. 368-375
-
-
Reiner, A.1
Yekutieli, D.2
Benjamini, Y.3
-
23
-
-
40749085197
-
Genetic and Environmental Interactions in Obesity and Type 2 Diabetes
-
DOI 10.1016/j.jada.2008.01.022, PII S0002822308000230
-
I Romao J Roth 2008 Genetic and environmental interactions in obesity and type 2 diabetes J Am Diet Assoc 108 S24 S28 10.1016/j.jada.2008.01.022 18358250 (Pubitemid 351389300)
-
(2008)
Journal of the American Dietetic Association
, vol.108
, Issue.4 SUPPL.
-
-
Romao, I.1
Roth, J.2
-
24
-
-
34548514198
-
Monoglyceride lipase as an enzyme hydrolyzing 2-arachidonoylglycerol
-
DOI 10.1002/cbdv.200790158
-
SM Saario JT Laitinen 2007 Monoglyceride lipase as an enzyme hydrolyzing 2-arachidonoylglycerol Chem Biodivers 4 1903 1913 10.1002/cbdv.200790158 17712832 (Pubitemid 47377208)
-
(2007)
Chemistry and Biodiversity
, vol.4
, Issue.8
, pp. 1903-1913
-
-
Saario, S.M.1
Laitinen, J.T.2
-
25
-
-
60149110931
-
The effect of WNT5B IVS3C>G on the susceptibility to type 2 diabetes in UK Caucasian subjects
-
10.1016/j.numecd.2008.02.009 18555673
-
KD Salpea DR Gable JA Cooper JW Stephens SJ Hurel HA Ireland MD Feher IF Godsland SE Humphries 2009 The effect of WNT5B IVS3C>G on the susceptibility to type 2 diabetes in UK Caucasian subjects Nutr Metab Cardiovasc Dis 19 2 140 145 10.1016/j.numecd.2008.02.009 18555673
-
(2009)
Nutr Metab Cardiovasc Dis
, vol.19
, Issue.2
, pp. 140-145
-
-
Salpea, K.D.1
Gable, D.R.2
Cooper, J.A.3
Stephens, J.W.4
Hurel, S.J.5
Ireland, H.A.6
Feher, M.D.7
Godsland, I.F.8
Humphries, S.E.9
-
26
-
-
0036079706
-
Acetyl-coenzyme A synthetase is a lipogenic enzyme controlled by SREBP-1 and energy status
-
11739104
-
H Sone H Shimano Y Sakakura N Inoue M Amemiya-Kudo N Yahagi M Osawa H Suzuki T Yokoo A Takahashi K Iida H Toyoshima A Iwama N Yamada 2002 Acetyl-coenzyme A synthetase is a lipogenic enzyme controlled by SREBP-1 and energy status Am J Physiol Endocrinol Metab 282 E222 E230 11739104
-
(2002)
Am J Physiol Endocrinol Metab
, vol.282
-
-
Sone, H.1
Shimano, H.2
Sakakura, Y.3
Inoue, N.4
Amemiya-Kudo, M.5
Yahagi, N.6
Osawa, M.7
Suzuki, H.8
Yokoo, T.9
Takahashi, A.10
Iida, K.11
Toyoshima, H.12
Iwama, A.13
Yamada, N.14
-
27
-
-
33847053555
-
Animal models of obesity
-
10.1111/j.1467-789X.2007.00319.x 17316303
-
J Speakman C Hambly S Mitchell E Krol 2007 Animal models of obesity Obes Rev 8 1 55 61 10.1111/j.1467-789X.2007.00319.x 17316303
-
(2007)
Obes Rev
, vol.8
, Issue.1
, pp. 55-61
-
-
Speakman, J.1
Hambly, C.2
Mitchell, S.3
Krol, E.4
-
28
-
-
15244341972
-
Microarray gene expression analysis of the Fob3b obesity QTL identifies positional candidate gene Sqle and perturbed cholesterol and glycolysis pathways
-
15598878
-
IM Stylianou M Clinton PD Keightley C Pritchard Z Tymowska-Lalanne L Bunger S Horvat 2005 Microarray gene expression analysis of the Fob3b obesity QTL identifies positional candidate gene Sqle and perturbed cholesterol and glycolysis pathways Physiol Genomics 20 224 232 15598878
-
(2005)
Physiol Genomics
, vol.20
, pp. 224-232
-
-
Stylianou, I.M.1
Clinton, M.2
Keightley, P.D.3
Pritchard, C.4
Tymowska-Lalanne, Z.5
Bunger, L.6
Horvat, S.7
-
29
-
-
23944509003
-
Acetyl-coenzyme A carboxylase: Crucial metabolic enzyme and attractive target for drug discovery
-
DOI 10.1007/s00018-005-5121-4
-
L Tong 2005 Acetyl-coenzyme A carboxylase: crucial metabolic enzyme and attractive target for drug discovery Cell Mol Life Sci 62 1784 1803 10.1007/s00018-005-5121-4 15968460 (Pubitemid 41188519)
-
(2005)
Cellular and Molecular Life Sciences
, vol.62
, Issue.16
, pp. 1784-1803
-
-
Tong, L.1
-
30
-
-
43449097716
-
Obesity: Prevalence, theories, medical consequences, management, and research directions
-
10.1186/1550-2783-2-2-4 18500955
-
C Wilborn J Beckham B Campbell T Harvey M Galbreath P La Bounty E Nassar J Wismann R Kreider 2005 Obesity: prevalence, theories, medical consequences, management, and research directions J Int Soc Sports Nutr 2 4 31 10.1186/1550-2783-2-2-4 18500955
-
(2005)
J Int Soc Sports Nutr
, vol.2
, pp. 4-31
-
-
Wilborn, C.1
Beckham, J.2
Campbell, B.3
Harvey, T.4
Galbreath, M.5
La Bounty, P.6
Nassar, E.7
Wismann, J.8
Kreider, R.9
-
31
-
-
0035687554
-
Assessing gene significance from cDNA microarray expression data via mixed models
-
DOI 10.1089/106652701753307520
-
RD Wolfinger G Gibson E Wolfinger L Bennett H Hamadeh P Bushel C Afshari RS Paules 2001 Assessing gene significance from cDNA microarray expression data via mixed models J Comput Biol 8 625 637 10.1089/106652701753307520 11747616 (Pubitemid 34053500)
-
(2001)
Journal of Computational Biology
, vol.8
, Issue.6
, pp. 625-637
-
-
Wolfinger, R.D.1
Gibson, G.2
Wolfinger, E.D.3
Bennett, L.4
Hamadeh, H.5
Bushel, P.6
Afshari, C.7
Paules, R.S.8
-
32
-
-
0030869004
-
Immune responses in mice deficient in Ly-GDI, a lymphoid-specific regulator of Rho GTpases
-
DOI 10.1016/S0161-5890(97)00053-9, PII S0161589097000539
-
L Yin P Schwartzberg TM Scharton-Kersten L Staudt M Lenardo 1997 Immune responses in mice deficient in Ly-GDI, a lymphoid-specific regulator of Rho GTPases Mol Immunol 34 481 491 10.1016/S0161-5890(97)00053-9 9307064 (Pubitemid 27373714)
-
(1997)
Molecular Immunology
, vol.34
, Issue.6
, pp. 481-491
-
-
Yin, L.1
Schwartzberg, P.2
Scharton-Kersten, T.M.3
Staudt, L.4
Lenardo, M.5
|