Anxiolytic-like effects of 8-acetylene imidazobenzodiazepines in a rhesus monkey conflict procedure

Neuropharmacology

Volumn 59, Issue 7-8, 2010, Pages 612-618

  Fischer, Bradford D ^a   Licata, Stephanie C ^a   Edwankar, Rahul V ^b   Wang, Zhi Jian ^b   Huang, Shengming ^b   He, Xiaohui ^b   Yu, Jianming ^b   Zhou, Hao ^b   Johnson, Edward M ^b   Cook, James M ^b   Furtmüller, Roman ^c   Ramerstorfer, Joachim ^c   Sieghart, Werner ^c   Roth, Bryan L ^d   Majumder, Samarpan ^d   Rowlett, James K ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF WISCONSIN MILWAUKEE   (United States)

^c Medical University of Vienna   (Austria)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Anxiety; Anxiolytic; Benzodiazepine; Conflict; GABA; Rhesus monkey

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR ALPHA1; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA2; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA3; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA5; 8 ACETYLENE IMIDAZOBENZODIAZEPINE DERIVATIVE; 8 ETHYNYL 6 (2 FLUOROPHENYL) 4 METHYL 4H 2,5,10B TRIAZABENZO[E]AZULENE 3 CARBOXYLIC ACID ETHYL ESTER; 8 ETHYNYL 6 (2 FLUOROPHENYL) 4H 2,5,10B TRIAZABENZO[E]AZULENE 3 CARBOXYLIC ACID ETHYL ESTER; 8 ETHYNYL 6 (2' PYRIDINE) 4H 2,5,10B TRIAZABENZO[E]AZULENE 3 CARBOXYLIC ACID ETHYL ESTER; 8 ETHYNYL 6 PHENYL 4H 2,5,10B TRIAZABENZO[E]AZULENE 3 CARBOXYLIC ACID ETHYL ESTER; BENZODIAZEPINE DERIVATIVE; DIAZEPAM; HZ 166; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; CONFLICT; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; ELECTRIC SHOCK; EMBRYO; FEMALE; HUMAN; HUMAN CELL; MALE; NONHUMAN; PRIORITY JOURNAL; RHESUS MONKEY; TRANQUILIZING ACTIVITY; XENOPUS LAEVIS;

ALKYNES; ANIMALS; ANTI-ANXIETY AGENTS; BENZODIAZEPINES; BINDING, COMPETITIVE; CELL LINE; CONFLICT (PSYCHOLOGY); FEMALE; GABA MODULATORS; HUMANS; IMIDAZOLES; MACACA MULATTA; MALE; OOCYTES; PATCH-CLAMP TECHNIQUES; RADIOLIGAND ASSAY; RATS; RECEPTORS, GABA-A; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; XENOPUS LAEVIS;

EID: 77958101055     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2010.08.011     Document Type: Article

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