Effects of different classes of partial benzodiazepine agonists on punished and unpunished responding in pigeons

Psychopharmacology

Volumn 144, Issue 4, 1999, Pages 405-410

  Kleven, Mark S ^a   Koek, Wouter ^a  

^a INSTITUT DE RECHERCHE PIERRE FABRE   (France)

Author keywords

Abecarnil; Alpidem; Anxiolytic; Benzodiazepine partial allosteric agonist; Bretazenil; CGS 9896; Conflict behavior; Imidazenil; Pigeon; ZK 91296; ZK 95962; Zolpidem

Indexed keywords

2 (4 CHLOROPHENYL) 5H PYRAZOLO[4,3 C]QUINOLIN 3 ONE; 4 METHOXYMETHYL 5 (1 METHYLETHOXY) BETA CARBOLINE 3 CARBOXYLIC ACID ETHYL ESTER; 5 BENZYLOXY 4 METHOXYMETHYL BETA CARBOLINE 3 CARBOXYLIC ACID ETHYL ESTER; ABECARNIL; ALPIDEM; BENZODIAZEPINE RECEPTOR STIMULATING AGENT; BRETAZENIL; IMIDAZENIL; ZOLPIDEM;

ALLOSTERISM; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONFLICT; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENTIATION; NONHUMAN; PIGEON; PRIORITY JOURNAL; PUNISHMENT; RECEPTOR AFFINITY; TRANQUILIZING ACTIVITY;

ANIMALS; ANTI-ANXIETY AGENTS; BENZODIAZEPINES; BENZODIAZEPINONES; COLUMBIDAE; CONFLICT (PSYCHOLOGY); GABA MODULATORS; IMIDAZOLES; MALE; PUNISHMENT; RECEPTORS, GABA-A;

EID: 0033023555     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130051024     Document Type: Article

References (26)

1. Azrin NH (1957) A technique for delivering shock to pigeons. J Exp Anal Behav 2:162-163
2. Barrett JE, Witkin JM, Mansbach RS, Skolnick P, Weissman BA (1986) Behavioral studies with anxiolytic drugs. III. Antipunishment actions of buspirone in the pigeon do not involve benzodiazepine receptor mechanisms. J Pharmacol Exp Ther 238: 1009-1013
3. Brocco MJ, Koek W, Degryse A-D, Colpaert FC (1990) Comparative studies on the anti-punishment effects of chlordiazepoxide, buspirone and ritanserin in the pigeon, Geller-Seifter and Vogel conflict procedures. Behav Pharmacol 1:403-418
4. Costa E, Guidotti A (1996) Benzodiazepines on trial: a research strategy for their rehabilitation. Trends Pharmacol Sci 17:192-200
5. Edgington ES (1987) Randomization tests. Dekker, New York
6. Gavish M, Katz Y, Bar-Ami S, Weizman R (1992) Biochemical, physiological, and pathological aspects of the peripheral benzodiazepine receptor. J Neurochem 31:1589-1601
7. A receptors. J Pharmacol Exp Ther 266:1018-1028
8. Gleeson S, Ahlers ST, Mansbach RS, Foust JM, Barrett JE (1989) Behavioral studies with anxiolytic drugs. VI. Effects on punished responding of drugs interacting with serotonin receptor subtypes. J Pharmacol Exp Ther 250:809-817
9. Griebel G, Sanger DJ, Perrault G (1996) Further evidence for differences between non-selective and BZ-1 (ω1) selective, benzodiazepine receptor ligands in murine models of "state" and "trait" anxiety. Neuropharmacology 35:1081-1091
10. Haefely W, Martin JR, Schoch P (1990) Novel anxiolytics that act as partial agonists at benzodiazpine receptors. Trends Pharmacol Sci 11:452-456
11. Jones GH, Schneider C, Schneider HH, Seidler J, Cole BJ, Stephens DN (1994) Comparison of several benzodiazepine receptor ligands in two models of anxiolytic activity in the mouse: an analysis based on fractional receptor occupancies. Psychopharmacology 114:191-199
12. Jordan AD, Kordik CP, Reitz AB, Sanfilippo PJ (1996) Central and peripheral nervous systems. Novel anxiolytic agents -1994 to present. Exp Opin Ther Pat 6:1047-1060
13. 2A/2C antagonist anxiolytics. 1. Antipunishment effects in the pigeon. J Pharmacol Exp Ther 276:388-397
14. Kleven MS, Koek W (1998) Effects of full benzodiazepine agonists on punished responding in pigeons and their relationship with clinical doses in humans. Psychopharmacology 141:206-212
15. 1A agonist with marked anxiolytic and antidepressant potential. J Pharmacol Exp Ther 287:266-283
16. Korpi ER, Mattila MJ, Wisden W, Lüddens H (1997) GABAA-receptor subtypes: clinical efficacy and selectivity of benzodiazepine site ligands. Ann Med 29:275-282
17. Litchfield JT Jr, Wilcoxon F (1949) A simplified method of evaluating dose-effect experiments. J Pharmacol Exp Ther 96:99-113
18. Martin JR, Schoch P, Jenck F, Moreau JL, Haefely WE (1993) Pharmacological characterization of benzodiazepine receptor ligands with intrinsic efficacies ranging from high to zero. Psychopharmacology 111:415-422
19. Nanry KP, Howard JL, Pollard GT (1991) Effects of buspirone and other anxiolytics on punished key-pecking in the pigeon. Drug Dev Res 24:269-276
20. New JS (1990) The discovery and development of buspirone: a new approach to the treatment of anxiety. Med Res Rev 10: 283-329
21. Sanger DJ, Zivkovic B (1994) Discriminative stimulus effects of alpidem, a new imidazopyridine anxiolytic. Psychopharmacology 113:395-403
22. Siegel S, Castellan NJ (1988) Nonparametric statistics for the behavioral sciences. McGraw-Hill, New York
23. Stephens DN, Schneider HH, Kehr W, Andrews JS, Rettig K-J, Turski L, Schmiechen R, Turner JD, Jensen LH, Petersen EN, Honore T, Hansen JB (1990) Abecarnil, a metabolically stable, anxioselective β-carboline acting at benzodiazepine receptors. J Pharmacol Exp Ther 253:334-343
24. Tallarida RJ, Murray RG (1987) Manual of pharmacological calculations with computer programs. Springer New York
25. Witkin JM, Acri JB, Wong G, Gleeson S, Barrett JE (1996) Behavioral and biochemical characterization of benzodiazepine receptor partial agonists in pigeons. J Pharmacol Exp Ther 277:87-96
26. Wuttke W, Kelleher RT (1970) Effects of some benzodiazepines on punished and unpunished behavior in the pigeon. J Pharmacol Exp Ther 172:397-405