Human transcriptome analysis reveals a potential role for active transport in the metabolism of Pseudomonas aeruginosa autoinducers

Microbes and Infection

Volumn 12, Issue 12-13, 2010, Pages 1042-1050

  Bryan, Amanda ^a   Watters, Chase ^a   Koenig, Lars ^b   Youn, Eunseog ^b   Olmos, Aaron ^c   Li, Guigen ^c   Williams, Simon C ^a   Rumbaugh, Kendra P ^a  

^a TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER SCHOOL OF MEDICINE   (United States)

^b Department of Electrical and Computer Engineering   (United States)

^c TEXAS TECH UNIVERSITY   (United States)

Author keywords

Interkingdom signaling; Microarray analysis; Pseudomonas aeruginosa; Quorum sensing; Xenobiotic

Indexed keywords

MESSENGER RNA; TRANSCRIPTOME;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG TRANSPORT; HUMAN; HUMAN CELL; MAMMAL CELL; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION; XENOBIOTIC METABOLISM;

4-BUTYROLACTONE; ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; CELLS, CULTURED; CYTOPLASM; EPITHELIAL CELLS; GENE EXPRESSION PROFILING; HOMOSERINE; HUMANS; METABOLIC NETWORKS AND PATHWAYS; MICE; MICROARRAY ANALYSIS; PSEUDOMONAS AERUGINOSA; TIME FACTORS; UP-REGULATION;

MAMMALIA; PSEUDOMONAS AERUGINOSA;

EID: 77958094341     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2010.07.006     Document Type: Article

References (39)

1. Parsek M.R., Greenberg E.P. Acyl-homoserine lactone quorum sensing in gram-negative bacteria: a signaling mechanism involved in associations with higher organisms. Proc. Natl. Acad. Sci. USA 2000, 97:8789-8793.
2. Lazdunski A.M., Ventre I., Sturgis J.N. Regulatory circuits and communication in gram-negative bacteria. Nat. Rev. Microbiol. 2004, 2:581-592.
3. Waters C.M., Bassler B.L. Quorum sensing: cell-to-cell communication in bacteria. Annu. Rev. Cell. Dev. Biol. 2005, 319-346.
4. Rumbaugh K.P., Griswold J.A., Hamood A.N. The role of quorum sensing in the in vivo virulence of Pseudomonas aeruginosa. Microbes Infect. 2000, 2:1721-1731.
5. Smith R.S., Iglewski B.H. P. aeruginosa quorum-sensing systems and virulence. Curr. Opin. Microbiol. 2003, 6:56-60.
6. Wu H., Song Z., Givskov M., Doring G., Worlitzsch D., Mathee K., Rygaard J., Hoiby N. Pseudomonas aeruginosa mutations in lasI and rhlI quorum sensing systems result in milder chronic lung infection. Microbiology 2001, 147:1105-1113.
7. Pearson J.P., Feldman M., Iglewski B.H., Prince A. Pseudomonas aeruginosa cell-to-cell signaling is required for virulence in a model of acute pulmonary infection. Infect. Immun. 2000, 68:4331-4334.
8. Lesprit P., Faurisson F., Join-Lambert O., Roudot-Thoraval F., Foglino M., Vissuzaine C., Carbon C. Role of the quorum-sensing system in experimental pneumonia due to Pseudomonas aeruginosa in rats. Am. J. Respir. Crit. Care Med. 2003, 167:1478-1482.
9. Imamura Y., Yanagihara K., Tomono K., Ohno H., Higashiyama Y., Miyazaki Y., Hirakata Y., Mizuta Y., Kadota J., Tsukamoto K., Kohno S. Role of Pseudomonas aeruginosa quorum-sensing systems in a mouse model of chronic respiratory infection. J. Med. Microbiol. 2005, 54:515-518.
10. Mittal R., Sharma S., Chhibber S., Harjai K. Contribution of quorum-sensing systems to virulence of Pseudomonas aeruginosa in an experimental pyelonephritis model. J. Microbiol. Immunol. Infect. 2006, 39:302-309.
11. Shiner E.K., Rumbaugh K.P., Williams S.C. Interkingdom signaling: deciphering the language of acyl homoserine lactones. FEMS Microbiol. Rev. 2005, 29:935-947.
12. Shiner E.K., Terentyev D., Bryan A., Sennoune S., Martinez-Zaguilan R., Li G., Gyorke S., Williams S.C., Rumbaugh K.P. Pseudomonas aeruginosa autoinducer modulates host cell responses through calcium signalling. Cell Microbiol. 2006, 8:1601-1610.
13. Smith R.S., Fedyk E.R., Springer T.A., Mukaida N., Iglewski B.H., Phipps R.P. IL-8 production in human lung fibroblasts and epithelial cells activated by the Pseudomonas autoinducer N-3-oxododecanoyl homoserine lactone is transcriptionally regulated by NF-kappa B and activator protein-2. J. Immunol. 2001, 167:366-374.
14. Smith R.S., Kelly R., Iglewski B.H., Phipps R.P. The Pseudomonas autoinducer N-(3-oxododecanoyl) homoserine lactone induces cyclooxygenase-2 and prostaglandin E2 production in human lung fibroblasts: implications for inflammation. J. Immunol. 2002, 169:2636-2642.
15. Tateda K., Ishii Y., Horikawa M., Matsumoto T., Miyairi S., Pechere J.C., Standiford T.J., Ishiguro M., Yamaguchi K. The Pseudomonas aeruginosa autoinducer N-3-oxododecanoyl homoserine lactone accelerates apoptosis in macrophages and neutrophils. Infect. Immun. 2003, 71:5785-5793.
16. Li L., Hooi D., Chhabra S.R., Pritchard D., Shaw P.E. Bacterial N-acylhomoserine lactone-induced apoptosis in breast carcinoma cells correlated with down-modulation of STAT3. Oncogene 2004, 23:4894-4902.
17. Jahoor A., Patel R., Bryan A., Do C., Krier J., Watters C., Wahli W., Li G., Williams S.C., Rumbaugh K.P. Peroxisome proliferator-activated receptors mediate host cell proinflammatory responses to Pseudomonas aeruginosa autoinducer. J. Bacteriol. 2008, 190:4408-4415.
18. Jacobi C.A., Schiffner F., Henkel M., Waibel M., Stork B., Daubrawa M., Eberl L., Gregor M., Wesselborg S. Effects of bacterial N-acyl homoserine lactones on human Jurkat T lymphocytes-OdDHL induces apoptosis via the mitochondrial pathway. Int. J. Med. Microbiol. 2009, 299:509-519.
19. Li H., Wang L., Ye L., Mao Y., Xie X., Xia C., Chen J., Lu Z., Song J. Influence of Pseudomonas aeruginosa quorum sensing signal molecule N-(3-oxododecanoyl) homoserine lactone on mast cells. Med. Microbiol. Immunol. 2009, 198:113-121.
20. Cooley M.A., Whittall C., Rolph M.S. Pseudomonas signal molecule 3-oxo-C12-homoserine lactone interferes with binding of rosiglitazone to human PPARgamma. Microbes Infect. 2010, 12:231-237.
21. Kaplan H.B., Greenberg E.P. Diffusion of autoinducer is involved in regulation of the Vibrio fischeri luminescence system. J. Bacteriol. 1985, 163:1210-1214.
22. Pearson J.P., Van Delden C., Iglewski B.H. Active efflux and diffusion are involved in transport of Pseudomonas aeruginosa cell-to-cell signals. J. Bacteriol. 1999, 181:1203-1210.
23. Williams S.C., Patterson E.K., Carty N.L., Griswold J.A., Hamood A.N., Rumbaugh K.P. Pseudomonas aeruginosa autoinducer enters and functions in mammalian cells. J. Bacteriol. 2004, 186:2281-2287.
24. Ritchie A.J., Whittall C., Lazenby J.J., Chhabra S.R., Pritchard D.I., Cooley M.A. The immunomodulatory Pseudomonas aeruginosa signalling molecule N-(3-oxododecanoyl)-L-homoserine lactone enters mammalian cells in an unregulated fashion. Immunol. Cell Biol. 2007, 596-602.
25. Chhabra S.R., Harty C., Hooi D.S., Daykin M., Williams P., Telford G., Pritchard D.I., Bycroft B.W. Synthetic analogues of the bacterial signal (quorum sensing) molecule N-(3-oxododecanoyl)-L-homoserine lactone as immune modulators. J. Med. Chem. 2003, 46:97-104.
26. Shiner E.K., Reddy S., Timmons C., Li G., Williams S.C., Rumbaugh K.P. Construction of a bacterial autoinducer detection system in mammalian cells. Biol. Proced. Online 2004, 6:268-276.
27. Smyth G.K., Yang Y.H., Speed T. Statistical issues in cDNA microarray data analysis. Methods Mol. Biol. 2003, 224:111-136.
28. Wilcoxon F. Individual comparison by ranking methods. Biometrics Bull. 1945, 1:80-83.
29. Massey F.J. The Kolmogorov-Smirnov test for goodness of fit. J. Am. Stat. Assoc. 1951, 46:68-78.
30. Benjamini Y., Drai D., Elmer G., Kafkafi N., Golani I. Controlling the false discovery rate in behavior genetics research. Behav. Brain Res. 2001, 125:279-284.
31. Ramsby M.L., Makowski G.S., Khairallah E.A. Differential detergent fractionation of isolated hepatocytes: biochemical, immunochemical and two-dimensional gel electrophoresis characterization of cytoskeletal and noncytoskeletal compartments. Electrophoresis 1994, 15:265-277.
32. Smith R.S., Harris S.G., Phipps R., Iglewski B. The Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxododecanoyl)homoserine lactone contributes to virulence and induces inflammation in vivo. J. Bacteriol. 2002, 184:1132-1139.
33. Rumbaugh K.P., Hamood A.N., Griswold J.A. Cytokine induction by the P. aeruginosa quorum sensing system during thermal injury. J. Surg. Res. 2004, 116:137-144.
34. Dean M., Rzhetsky A., Allikmets R. The human ATP-binding cassette (ABC) transporter superfamily. Genome Res. 2001, 11:1156-1166.
35. Deeley R.G., Westlake C., Cole S.P. Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins. Physiol. Rev. 2006, 86:849-899.
36. Takahashi K., Kimura Y., Kioka N., Matsuo M., Ueda K. Purification and ATPase activity of human ABCA1. J. Biol. Chem. 2006, 281:10760-10768.
37. Nieland T.J., Chroni A., Fitzgerald M.L., Maliga Z., Zannis V.I., Kirchhausen T., Krieger M. Cross-inhibition of SR-BI- and ABCA1-mediated cholesterol transport by the small molecules BLT-4 and glyburide. J. Lipid. Res. 2004, 45:1256-1265.
38. Putman M., Van Veen H.W., Degener J.E., Konings W.N. Antibiotic resistance: era of the multidrug pump. Mol. Microbiol. 2000, 36:772-773.
39. Gadsby D.C., Vergani P., Csanady L. The ABC protein turned chloride channel whose failure causes cystic fibrosis. Nature 2006, 440:477-483.