Mast cell degranulation is essential for anastomotic healing in well perfused and poorly perfused rat colon

Journal of Surgical Research

Volumn 164, Issue 1, 2010, Pages

  Coneely, John ^b   Kennelly, Rory ^a   Bouchier Hayes, D ^b   Winter, Desmond C ^a  

^a ST VINCENT S UNIVERSITY HOSPITAL   (Ireland)

^b ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

Author keywords

ischemia; mast cell; wound healing

Indexed keywords

COMPOUND 48-80; HYDROXYPROLINE; INTERLEUKIN 6; KETOTIFEN; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL FUNCTION; COLON ANASTOMOSIS; COLON BLOOD FLOW; COMPETITIVE INHIBITION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; INTESTINE ISCHEMIA; MALE; MAST CELL DEGRANULATION; MESENTERIC ARTERY; NONHUMAN; ORGAN PERFUSION; PRIORITY JOURNAL; RAT; VASCULARIZATION; WISTAR RAT; WOUND HEALING; WOUND HEALING IMPAIRMENT;

ANASTOMOSIS, SURGICAL; ANGIOGRAPHY; ANIMALS; CELL DEGRANULATION; COLON; HISTAMINE H1 ANTAGONISTS; ISCHEMIA; KETOTIFEN; MALE; MAST CELLS; P-METHOXY-N-METHYLPHENETHYLAMINE; POSTOPERATIVE COMPLICATIONS; RATS; RATS, WISTAR; WOUND HEALING;

EID: 77958086760     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2010.04.035     Document Type: Article

References (23)

1. R.J. Heald, B.J. Moran, and R.D. Ryall Rectal cancer: The Basingstoke experience of total mesorectal excision, 1978-1997 ArchSurg 133 1998 894
2. F. Stipa, D.B. Chessin, and J. Shia A pathologic complete response of rectal cancer to preoperative combined-modality therapy results in improved oncological outcome compared with those who achieve no downstaging on the basis of preoperative endorectal ultrasonography Ann Surg Oncol 3 2006 1047
3. A. Alves, Y. Panis, and M. Pocard Management of anastomotic leakage after nondiverted large bowel resection J Am Coll Surg 189 1999 554
4. T.P. Kingham, and H.L. Pachter Colonic anastomotic leak: Risk factors, diagnosis, and treatment J Am Coll Surg 208 2009 269
5. P. Matthiessen, O. Hallbook, and M. Andersson Risk factors for anastomotic leakage after anterior resection of the rectum Colorectal Dis 6 2004 462
6. M.G. Tonnesen, X. Feng, and R.A. Clark Angiogenesis in wound healing J Investig Dermatol Symp Proc 5 2000 40
7. K. Norrby Mast cells and angiogenesis APMIS 110 2002 355
8. H. Serna, M. Porras, and P. Vergara Mast cell stabilizer ketotifen [4-(1-methyl-4-piperidylidene)-4h-benzo[4,5]cyclohepta[1,2-b]thiophen-10(9 H)-one fumarate] prevents mucosal mast cell hyperplasia and intestinal dysmotility in experimental T richinella spiralis inflammation in the rat J Pharmacol Exp Ther 319 2006 1104
9. A.L. McGowen, L.P. Hale, and C.P. Shelburne The mast cell activator compound 48/80 is safe and effective when used as an adjuvant for intradermal immunization with Bacillus anthracis protective antigen Vaccine 27 2009 3544
10. G.K. Reddy, and C.S. Enwemeka A simplified method for the analysis of hydroxyproline in biological tissues Clin Biochem 29 1996 225
11. H. Tulchinsky, M. Rabau, and E. Shacham-Shemueli Can rectal cancers with pathologic T0 after neoadjuvant chemoradiation (ypT0) be treated by transanal excision alone? Ann Surg Oncol 13 2006 347
12. H. Rutten, M. den Dulk, and V. Lemmens Survival of elderly rectal cancer patients not improved: Analysis of population based data on the impact of TME surgery Eur J Cancer 43 2007 2295
13. (http://seer.cancer.gov/csr/1975-2006/results-single/sect-01-table. 11-2pgs.pdf. Accessed January 10, 2010.
14. H.J. Rutten, D.M. den, V.E. Lemmens, and d.V. van Controversies of total mesorectal excision for rectal cancer in elderly patients Lancet Oncol 9 2008 494
15. G.G. Chude, N.V. Rayate, and V. Patris Defunctioning loop ileostomy with low anterior resection for distal rectal cancer: Should we make an ileostomy as a routine procedure? A prospective randomized study Hepatogastroenterology 55 2008 1562
16. G. Marjanovic, E. Juttner, and A. zur Hausen Ischemic preconditioning improves stability of intestinal anastomoses in rats Int J Colorectal Dis 24 2009 975
17. L. Fresno, D. Fondevila, and O. Bambo Effects of platelet-rich plasma on intestinal wound healing in pigs Vet J 2009
18. I. Pascual, G.F. de Miguel, and U.A. Gomez-Pinedo Adipose-derived mesenchymal stem cells in biosutures do not improve healing of experimental colonic anastomoses Br J Surg 95 2008 1180
19. T.C. Moon, C.D. St Laurent, and K.E. Morris Advances in mast cell biology: New understanding of heterogeneity and function Mucosal Immunol 3 2010 111
20. L.C. Yu The epithelial gatekeeper against food allergy Pediatr Neonatol 50 2009 247
21. C. Noli, and A. Miolo The mast cell in wound healing Vet Dermatol 12 2001 303
22. K. Weller, K. Foitzik, and R. Paus Mast cells are required for normal healing of skin wounds in mice FASEB J 20 2006 2366
23. D.M. Sedgwick, and A. Ferguson Dose-response studies of depletion and repopulation of rat intestinal mucosal mast cells after irradiation Int J Radiat Biol 65 1994 483