Adipose-derived mesenchymal stem cells in biosutures do not improve healing of experimental colonic anastomoses

British Journal of Surgery

Volumn 95, Issue 9, 2008, Pages 1180-1184

  Pascual, I ^a,b   De Miguel, G Fernández ^c   Gomez Pinedo U A ^d,e   De Miguel, F ^a   Arranz, M Garaía ^a   Garcia Olmo D ^a,b  

^a HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^c Centro de Investigatión Príncipe Felipe ^*

^d Centro de Investigatión Príncipe Felipe   (Spain)

^e HOSPITAL CIVIL DE GUADALAJARA FRAY ANTONIO ALCALDE   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CLINICAL EVALUATION; COLON ANASTOMOSIS; CONFERENCE PAPER; CONTROLLED STUDY; HISTOPATHOLOGY; MESENCHYMAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; STATISTICAL SIGNIFICANCE; SUTURE; WOUND HEALING;

ADIPOSE TISSUE; ANASTOMOSIS, SURGICAL; ANIMALS; COLON; FEASIBILITY STUDIES; MESENCHYMAL STEM CELLS; RATS; SUTURE TECHNIQUES; SUTURES; WOUND HEALING;

EID: 50249178579     PISSN: 00071323     EISSN: 13652168     Source Type: Journal    
DOI: 10.1002/bjs.6242     Document Type: Conference Paper

References (11)

1. Thompson SK, Chang EY, Jobe BA. Clinical review: healing in gastrointestinal anastomoses, part I. Microsurgery 2006; 26: 131-136.
2. Zuk PA, Zhu M, Ashjian P, De Ugarte DA, Huang JI, Mizuno H et al. Human adipose tissue is a source of multipotent stem cells. Mol Biol Cell 2002; 13:4279-4295.
3. Puissant B, Barreau C, Bourin P, Clavel C, Corre J, Bousquet C et al. Immunomodulatory effect of human adipose tissue-derived adult stem cells: comparison with bone marrow mesenchymal stem cells. Br J Haematol 200S; 129: 118-129.
4. Fraser JK, Wulur I, Alfonso Z, Hedrick MH. Fat tissue: an underappreciated source of stem cells for biotechnology. Trends Biotechnol 2006; 24: 150-154.
5. García-Olmo D, García-Arranz M, Herreros MD, Pascual I, Peiro C, Rodríguez-Montes JA. A phase I clinical trial of the treatment of Crohn's fistula by adipose mesenchymal stem cell transplantation. Dis Colon Rectum 2005; 48: 1416-1423.
6. García-Olmo D, Lucas FJ, Paya J. Relationship between peritoneum adhesion phenomena and the experimental resistance of colon anastomoses: influence of omentoplasty. Eur Surg Res 1996; 28: 315-322.
7. García-OImo D, Payá J, Lucas FJ, García-OImo DC. The effects of the pharmacological manipulation of postoperative intestinal motility on colonic anastomosis. An experimental study in a rat model. Int J Colorectal Dis 1997; 12: 73-77.
8. García-OImo DC, Payá J, García-OImo D. Effects of perioperative treatment with TNP-470 on the resistance of colonic anastomoses in rats. Dig Surg 2000; 17: 154-159.
9. Le Blanc K. Inmunomodulatory effects of fetal and adult mesenchymal stem cells. Cytotherapy 2003; 5: 485-489.
10. Lucas PA, Warejcka DJ, Zhang LM, Newman WH, Young HE. Effect of rat mesenchymal stem cells on development of abdominal adhesions after surgery. J Surg Res 1996; 62: 229-232.
11. Schäffler A, Büchler C. Concise review: adipose tissue-derived stromal cells - basic and clinical implications for novel cell-based therapies. Stem Cells 2007; 25: 818-827.