Holo-Ni(II) Hp NikR is an asymmetric tetramer containing two different nickel-binding sites

Journal of the American Chemical Society

Volumn 132, Issue 41, 2010, Pages 14447-14456

  West, Abby L ^a   St John, Franz ^a   Lopes, Pedro E M ^a   MacKerell Jr , Alexander D ^a   Pozharski, Edwin ^a   Michel, Sarah L J ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AS-LIGANDS; BINDING AFFINITIES; COORDINATE GEOMETRY; COORDINATION ENVIRONMENT; COORDINATION GEOMETRY; DFT CALCULATION; HELICOBACTER PYLORI; MASTER REGULATORS; METALLOREGULATORY PROTEIN; NICKEL IONS; PYROCOCCUS HORIKOSHII; SPATIAL LOCATION; SQUARE PLANAR GEOMETRY; TETRAMERS; WATER MOLECULE;

AMINO ACIDS; BINDING ENERGY; BINDING SITES; BIOCHEMISTRY; COMPUTATIONAL GEOMETRY; CRYSTAL STRUCTURE; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; IONS; LIGANDS; SULFUR COMPOUNDS; TRANSCRIPTION; TRANSCRIPTION FACTORS;

NICKEL;

BACTERIAL PROTEIN; HISTIDINE; NICKEL; PROTEIN NIKR; TETRAMER; TRYPTOPHAN; UNCLASSIFIED DRUG; WATER;

ARTICLE; BINDING AFFINITY; BINDING SITE; CRYSTAL STRUCTURE; DENSITY FUNCTIONAL THEORY; ESCHERICHIA COLI; GENE EXPRESSION; HELICOBACTER PYLORI; HYDROGEN BOND; ISOTHERMAL TITRATION CALORIMETRY; METAL BINDING; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NONHUMAN; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN STRUCTURE; PYROCOCCUS HORIKOSHII; STOICHIOMETRY;

BACTERIAL PROTEINS; BASE SEQUENCE; BINDING SITES; BIOPOLYMERS; CALORIMETRY; CRYSTALLOGRAPHY, X-RAY; DNA PRIMERS; FLUORESCENCE POLARIZATION; HELICOBACTER PYLORI; HYDROGEN BONDING; MODELS, MOLECULAR; NICKEL; REPRESSOR PROTEINS;

EID: 77958063110     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja104118r     Document Type: Article

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