Indoxyl sulfate stimulates monocyte chemoattractant protein-1 expression in human umbilical vein endothelial cells by inducing oxidative stress through activation of the NADPH oxidase-nuclear factor-κB pathway

Circulation Journal

Volumn 74, Issue 10, 2010, Pages 2216-2224

  Masai, Natsumi ^a   Tatebe, Junko ^a   Yoshino, Gen ^a   Morita, Toshisuke ^a  

^a TOHO UNIVERSITY   (Japan)

Author keywords

Cardiovascular disease; Chronic kidney disease; Indoxyl sulfate; Monocyte chemoattractant protein 1; Oxidative stress

Indexed keywords

APOCYNIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDICAN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MONOCYTE CHEMOTACTIC PROTEIN 1; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SYNAPTOPHYSIN;

ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME INHIBITION; GENE EXPRESSION; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UMBILICAL VEIN;

ATHEROSCLEROSIS; CELLS, CULTURED; CHEMOKINE CCL2; ENDOTHELIAL CELLS; HUMANS; INDICAN; NADPH OXIDASE; NF-KAPPA B; OXIDATIVE STRESS; RENAL INSUFFICIENCY, CHRONIC; SIGNAL TRANSDUCTION; UMBILICAL VEINS;

EID: 77958044174     PISSN: 13469843     EISSN: 13474820     Source Type: Journal    
DOI: 10.1253/circj.CJ-10-0117     Document Type: Article

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