메뉴 건너뛰기




Volumn 32, Issue 3, 2009, Pages 194-200

Oral adsorbent AST-120 ameliorates endothelial dysfunction independent of renal function in rats with subtotal nephrectomy

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; AST 120; CREATINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INDICAN; MESSENGER RNA; OXIDOREDUCTASE; PROTEIN P47; PROTEIN P47 PHOX; SERINE; UNCLASSIFIED DRUG;

EID: 68249135443     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1038/hr.2008.29     Document Type: Article
Times cited : (39)

References (36)
  • 1
    • 4644221457 scopus 로고    scopus 로고
    • Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization
    • Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med 2004; 351: 1296-1305.
    • (2004) N Engl J Med , vol.351 , pp. 1296-1305
    • Go, A.S.1    Chertow, G.M.2    Fan, D.3    McCulloch, C.E.4    Hsu, C.Y.5
  • 2
    • 33750741932 scopus 로고    scopus 로고
    • Renin-angiotensin-aldosterone system and progression of renal disease
    • Ruster C, Wolf G. Renin-angiotensin-aldosterone system and progression of renal disease. J Am Soc Nephrol 2006; 17: 2985-2991.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 2985-2991
    • Ruster, C.1    Wolf, G.2
  • 3
    • 33645061521 scopus 로고    scopus 로고
    • Evidence for renoprotection by blockade of the renin-angiotensin-aldosterone system in hypertension and diabetes
    • Karalliedde J, Viberti G. Evidence for renoprotection by blockade of the renin-angiotensin-aldosterone system in hypertension and diabetes. J Hum Hypertens 2006; 20: 239-253.
    • (2006) J Hum Hypertens , vol.20 , pp. 239-253
    • Karalliedde, J.1    Viberti, G.2
  • 4
    • 33750736646 scopus 로고    scopus 로고
    • The chronic kidney disease epidemic: Stepping back and looking forward
    • Kiberd B. The chronic kidney disease epidemic: Stepping back and looking forward. J Am Soc Nephrol 2006; 17: 2967-2973.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 2967-2973
    • Kiberd, B.1
  • 5
    • 0030663544 scopus 로고    scopus 로고
    • The protein metabolite hypothesis, a model for the progression of renal failure: An oral adsorbent lowers indoxyl sulfate levels in undialyzed uremic patients
    • Niwa T, Nomura T, Sugiyama S, Miyazaki T, Tsukushi S, Tsutsui S. The protein metabolite hypothesis, a model for the progression of renal failure: An oral adsorbent lowers indoxyl sulfate levels in undialyzed uremic patients. Kidney Int (Suppl) 1997; 52: S23-S28.
    • (1997) Kidney Int (Suppl) , vol.52
    • Niwa, T.1    Nomura, T.2    Sugiyama, S.3    Miyazaki, T.4    Tsukushi, S.5    Tsutsui, S.6
  • 6
    • 0031460218 scopus 로고    scopus 로고
    • Effects of oral adsorbent AST-120 on the progression of chronic renal failure: A randomized controlled study
    • Owada A, Nakao M, Koike J, Ujiie K, Tomita K, Shiigai T. Effects of oral adsorbent AST-120 on the progression of chronic renal failure: A randomized controlled study. Kidney Int (Suppl) 1997; 52: S188-S190.
    • (1997) Kidney Int (Suppl) , vol.52
    • Owada, A.1    Nakao, M.2    Koike, J.3    Ujiie, K.4    Tomita, K.5    Shiigai, T.6
  • 7
    • 33846794398 scopus 로고    scopus 로고
    • Prospective randomized study evaluating the efficacy of the spherical adsorptive carbon AST-120 in chronic kidney disease patients with moderate decrease in renal function
    • Shoji T, Wada A, Inoue K, Hayashi D, Tomida K, Furumatsu Y, Kaneko T, Okada N, Fukuhara Y, Imai E, Tsubakihara Y. Prospective randomized study evaluating the efficacy of the spherical adsorptive carbon AST-120 in chronic kidney disease patients with moderate decrease in renal function. Nephron Clin Pract 2007; 105: C99-c107.
    • (2007) Nephron Clin Pract , vol.105
    • Shoji, T.1    Wada, A.2    Inoue, K.3    Hayashi, D.4    Tomida, K.5    Furumatsu, Y.6    Kaneko, T.7    Okada, N.8    Fukuhara, Y.9    Imai, E.10    Tsubakihara, Y.11
  • 8
    • 25644458631 scopus 로고    scopus 로고
    • Kremezin (AST-120) delays the progression of diabetic nephropathy in Japanese type 2 diabetic patients
    • Shimizu H, Okada S, Shinsuke OI, Mori M. Kremezin (AST-120) delays the progression of diabetic nephropathy in Japanese type 2 diabetic patients. Diabetes Care 2005; 28: 2590.
    • (2005) Diabetes Care , vol.28 , pp. 2590
    • Shimizu, H.1    Okada, S.2    Shinsuke, O.I.3    Mori, M.4
  • 9
    • 0035996187 scopus 로고    scopus 로고
    • Effects of oral adsorbent AST-120 (Kremezin) on renal function and glomerular injury in early-stage renal failure of subtotal nephrectomized rats
    • Kobayashi N, Maeda A, Horikoshi S, Shirato I, Tomino Y, Ise M. Effects of oral adsorbent AST-120 (Kremezin) on renal function and glomerular injury in early-stage renal failure of subtotal nephrectomized rats. Nephron 2002; 91: 480-485.
    • (2002) Nephron , vol.91 , pp. 480-485
    • Kobayashi, N.1    Maeda, A.2    Horikoshi, S.3    Shirato, I.4    Tomino, Y.5    Ise, M.6
  • 10
    • 0142156124 scopus 로고    scopus 로고
    • Protein restriction and AST-120 improve lipoprotein lipase and VLDL receptor in focal glomerulosclerosis
    • Sato T, Liang K, Vaziri ND. Protein restriction and AST-120 improve lipoprotein lipase and VLDL receptor in focal glomerulosclerosis. Kidney Int 2003; 64: 1780-1786.
    • (2003) Kidney Int , vol.64 , pp. 1780-1786
    • Sato, T.1    Liang, K.2    Vaziri, N.D.3
  • 11
    • 0033762864 scopus 로고    scopus 로고
    • An oral sorbent reduces overload of indoxyl sulphate and gene expression of TGF-β1 in uraemic rat kidneys
    • Miyazaki T, Aoyama I, Ise M, Seo H, Niwa T. An oral sorbent reduces overload of indoxyl sulphate and gene expression of TGF-β1 in uraemic rat kidneys. Nephrol Dial Transplant 2000; 15: 1773-1781.
    • (2000) Nephrol Dial Transplant , vol.15 , pp. 1773-1781
    • Miyazaki, T.1    Aoyama, I.2    Ise, M.3    Seo, H.4    Niwa, T.5
  • 12
    • 0033936092 scopus 로고    scopus 로고
    • Oral adsorbent AST-120 ameliorates interstitial fibrosis and transforming growth factor-β1 expression in spontaneously diabetic (OLETF) rats
    • Aoyama I, Shimokata K, Niwa T. Oral adsorbent AST-120 ameliorates interstitial fibrosis and transforming growth factor-β1 expression in spontaneously diabetic (OLETF) rats. Am J Nephrol 2000; 20: 232-241.
    • (2000) Am J Nephrol , vol.20 , pp. 232-241
    • Aoyama, I.1    Shimokata, K.2    Niwa, T.3
  • 13
    • 2342564944 scopus 로고    scopus 로고
    • Oral adsorbent AST-120 decreases carotid intima-media thickness and arterial stiffness in patients with chronic renal failure
    • Nakamura T, Kawagoe Y, Matsuda T, Ueda Y, Shimada N, Ebihara I, Koide H. Oral adsorbent AST-120 decreases carotid intima-media thickness and arterial stiffness in patients with chronic renal failure. Kidney Blood Press Res 2004; 27: 121-126.
    • (2004) Kidney Blood Press Res , vol.27 , pp. 121-126
    • Nakamura, T.1    Kawagoe, Y.2    Matsuda, T.3    Ueda, Y.4    Shimada, N.5    Ebihara, I.6    Koide, H.7
  • 15
    • 44449148845 scopus 로고    scopus 로고
    • Indoxyl sulphate promotes aortic calcification with expression of osteoblast-specific proteins in hypertensive rats
    • Adijiang A, Goto S, Uramoto S, Nishijima F, Niwa T. Indoxyl sulphate promotes aortic calcification with expression of osteoblast-specific proteins in hypertensive rats. Nephrol Dial Transplant 2008; 23 1892-1901.
    • (2008) Nephrol Dial Transplant , vol.23 , pp. 1892-1901
    • Adijiang, A.1    Goto, S.2    Uramoto, S.3    Nishijima, F.4    Niwa, T.5
  • 16
    • 33645450504 scopus 로고    scopus 로고
    • Endothelial dysfunction contributes to renal function-associated cardiovascular mortality in a population with mild renal insufficiency: The Hoorn study
    • Stam F, van Guldener C, Becker A, Dekker JM, Heine RJ, Bouter LM, Stehouwer CD. Endothelial dysfunction contributes to renal function-associated cardiovascular mortality in a population with mild renal insufficiency: The Hoorn study. J Am Soc Nephrol 2006; 17 537-545.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 537-545
    • Stam, F.1    van Guldener, C.2    Becker, A.3    Dekker, J.M.4    Heine, R.J.5    Bouter, L.M.6    Stehouwer, C.D.7
  • 18
    • 0242669257 scopus 로고    scopus 로고
    • Uremic toxins of organic anions up-regulate PAI-1 expression by induction of NF-κB and free radical in proximal tubular cells
    • Motojima M, Hosokawa A, Yamato H, Muraki T, Yoshioka T. Uremic toxins of organic anions up-regulate PAI-1 expression by induction of NF-κB and free radical in proximal tubular cells. Kidney Int 2003; 63: 1671-1680.
    • (2003) Kidney Int , vol.63 , pp. 1671-1680
    • Motojima, M.1    Hosokawa, A.2    Yamato, H.3    Muraki, T.4    Yoshioka, T.5
  • 19
    • 41849103757 scopus 로고    scopus 로고
    • Indoxyl sulfate reduces superoxide scavenging activity in the kidneys of normal and uremic rats
    • Owada S, Goto S, Bannai K, Hayashi H, Nishijima F, Niwa T. Indoxyl sulfate reduces superoxide scavenging activity in the kidneys of normal and uremic rats. Am J Nephrol 2008; 28: 446-454.
    • (2008) Am J Nephrol , vol.28 , pp. 446-454
    • Owada, S.1    Goto, S.2    Bannai, K.3    Hayashi, H.4    Nishijima, F.5    Niwa, T.6
  • 20
  • 23
    • 44649160542 scopus 로고    scopus 로고
    • Pioglitazone enhances the antihypertensive and renoprotective effects of candesartan in Zucker obese rats fed a high-protein diet
    • Namikoshi T, Tomita N, Satoh M, Haruna Y, Kobayashi S, Komai N, Sasaki T, Kashihara N. Pioglitazone enhances the antihypertensive and renoprotective effects of candesartan in Zucker obese rats fed a high-protein diet. Hypertens Res 2008; 31: 745-755.
    • (2008) Hypertens Res , vol.31 , pp. 745-755
    • Namikoshi, T.1    Tomita, N.2    Satoh, M.3    Haruna, Y.4    Kobayashi, S.5    Komai, N.6    Sasaki, T.7    Kashihara, N.8
  • 25
    • 4344683549 scopus 로고    scopus 로고
    • Homocysteine induced impairment of nitric oxide-dependent vasorelaxation is reversible by the superoxide dismutase mimetic TEMPOL
    • Hucks D, Thuraisingham RC, Raftery MJ, Yaqoob MM. Homocysteine induced impairment of nitric oxide-dependent vasorelaxation is reversible by the superoxide dismutase mimetic TEMPOL. Nephrol Dial Transplant 2004; 19: 1999-2005.
    • (2004) Nephrol Dial Transplant , vol.19 , pp. 1999-2005
    • Hucks, D.1    Thuraisingham, R.C.2    Raftery, M.J.3    Yaqoob, M.M.4
  • 27
    • 34249915064 scopus 로고    scopus 로고
    • An oral adsorbent, AST-120 protects against the progression of oxidative stress by reducing the accumulation of indoxyl sulfate in the systemic circulation in renal failure
    • Shimoishi K, Anraku M, Kitamura K, Tasaki Y, Taguchi K, Hashimoto M, Fukunaga E, Maruyama T, Otagiri M. An oral adsorbent, AST-120 protects against the progression of oxidative stress by reducing the accumulation of indoxyl sulfate in the systemic circulation in renal failure. Pharm Res 2007; 24: 1283-1289.
    • (2007) Pharm Res , vol.24 , pp. 1283-1289
    • Shimoishi, K.1    Anraku, M.2    Kitamura, K.3    Tasaki, Y.4    Taguchi, K.5    Hashimoto, M.6    Fukunaga, E.7    Maruyama, T.8    Otagiri, M.9
  • 31
    • 33645780634 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase in vascular disease: From marvel to menace
    • Förstermann U, Münzel T. Endothelial nitric oxide synthase in vascular disease: From marvel to menace. Circulation 2006; 113 1708-1714.
    • (2006) Circulation , vol.113 , pp. 1708-1714
    • Förstermann, U.1    Münzel, T.2
  • 32
    • 0029805172 scopus 로고    scopus 로고
    • Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and ugly
    • Beckman JS, Koppenol WH. Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. Am J Physiol 1996; 271: C1424-C1437.
    • (1996) Am J Physiol , vol.271
    • Beckman, J.S.1    Koppenol, W.H.2
  • 35
    • 33847668826 scopus 로고    scopus 로고
    • Indoxyl sulphate and atherosclerotic risk factors in hemodialysis patients
    • Taki K, Tsuruta Y, Niwa T. Indoxyl sulphate and atherosclerotic risk factors in hemodialysis patients. Am J Nephrol 2007; 27: 30-35.
    • (2007) Am J Nephrol , vol.27 , pp. 30-35
    • Taki, K.1    Tsuruta, Y.2    Niwa, T.3
  • 36
    • 25844513144 scopus 로고    scopus 로고
    • Oxidative stress and nitric oxide deficiency in the kidney: A critical link to hypertension?
    • Wilcox CS. Oxidative stress and nitric oxide deficiency in the kidney: A critical link to hypertension? Am J Physiol Regul Integr Comp Physiol 2005; 289: 913-935.
    • (2005) Am J Physiol Regul Integr Comp Physiol , vol.289 , pp. 913-935
    • Wilcox, C.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.