-
1
-
-
4644221457
-
Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization
-
Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med 2004; 351: 1296-1305.
-
(2004)
N Engl J Med
, vol.351
, pp. 1296-1305
-
-
Go, A.S.1
Chertow, G.M.2
Fan, D.3
McCulloch, C.E.4
Hsu, C.Y.5
-
2
-
-
33750741932
-
Renin-angiotensin-aldosterone system and progression of renal disease
-
Ruster C, Wolf G. Renin-angiotensin-aldosterone system and progression of renal disease. J Am Soc Nephrol 2006; 17: 2985-2991.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 2985-2991
-
-
Ruster, C.1
Wolf, G.2
-
3
-
-
33645061521
-
Evidence for renoprotection by blockade of the renin-angiotensin-aldosterone system in hypertension and diabetes
-
Karalliedde J, Viberti G. Evidence for renoprotection by blockade of the renin-angiotensin-aldosterone system in hypertension and diabetes. J Hum Hypertens 2006; 20: 239-253.
-
(2006)
J Hum Hypertens
, vol.20
, pp. 239-253
-
-
Karalliedde, J.1
Viberti, G.2
-
4
-
-
33750736646
-
The chronic kidney disease epidemic: Stepping back and looking forward
-
Kiberd B. The chronic kidney disease epidemic: Stepping back and looking forward. J Am Soc Nephrol 2006; 17: 2967-2973.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 2967-2973
-
-
Kiberd, B.1
-
5
-
-
0030663544
-
The protein metabolite hypothesis, a model for the progression of renal failure: An oral adsorbent lowers indoxyl sulfate levels in undialyzed uremic patients
-
Niwa T, Nomura T, Sugiyama S, Miyazaki T, Tsukushi S, Tsutsui S. The protein metabolite hypothesis, a model for the progression of renal failure: An oral adsorbent lowers indoxyl sulfate levels in undialyzed uremic patients. Kidney Int (Suppl) 1997; 52: S23-S28.
-
(1997)
Kidney Int (Suppl)
, vol.52
-
-
Niwa, T.1
Nomura, T.2
Sugiyama, S.3
Miyazaki, T.4
Tsukushi, S.5
Tsutsui, S.6
-
6
-
-
0031460218
-
Effects of oral adsorbent AST-120 on the progression of chronic renal failure: A randomized controlled study
-
Owada A, Nakao M, Koike J, Ujiie K, Tomita K, Shiigai T. Effects of oral adsorbent AST-120 on the progression of chronic renal failure: A randomized controlled study. Kidney Int (Suppl) 1997; 52: S188-S190.
-
(1997)
Kidney Int (Suppl)
, vol.52
-
-
Owada, A.1
Nakao, M.2
Koike, J.3
Ujiie, K.4
Tomita, K.5
Shiigai, T.6
-
7
-
-
33846794398
-
Prospective randomized study evaluating the efficacy of the spherical adsorptive carbon AST-120 in chronic kidney disease patients with moderate decrease in renal function
-
Shoji T, Wada A, Inoue K, Hayashi D, Tomida K, Furumatsu Y, Kaneko T, Okada N, Fukuhara Y, Imai E, Tsubakihara Y. Prospective randomized study evaluating the efficacy of the spherical adsorptive carbon AST-120 in chronic kidney disease patients with moderate decrease in renal function. Nephron Clin Pract 2007; 105: C99-c107.
-
(2007)
Nephron Clin Pract
, vol.105
-
-
Shoji, T.1
Wada, A.2
Inoue, K.3
Hayashi, D.4
Tomida, K.5
Furumatsu, Y.6
Kaneko, T.7
Okada, N.8
Fukuhara, Y.9
Imai, E.10
Tsubakihara, Y.11
-
8
-
-
25644458631
-
Kremezin (AST-120) delays the progression of diabetic nephropathy in Japanese type 2 diabetic patients
-
Shimizu H, Okada S, Shinsuke OI, Mori M. Kremezin (AST-120) delays the progression of diabetic nephropathy in Japanese type 2 diabetic patients. Diabetes Care 2005; 28: 2590.
-
(2005)
Diabetes Care
, vol.28
, pp. 2590
-
-
Shimizu, H.1
Okada, S.2
Shinsuke, O.I.3
Mori, M.4
-
9
-
-
0035996187
-
Effects of oral adsorbent AST-120 (Kremezin) on renal function and glomerular injury in early-stage renal failure of subtotal nephrectomized rats
-
Kobayashi N, Maeda A, Horikoshi S, Shirato I, Tomino Y, Ise M. Effects of oral adsorbent AST-120 (Kremezin) on renal function and glomerular injury in early-stage renal failure of subtotal nephrectomized rats. Nephron 2002; 91: 480-485.
-
(2002)
Nephron
, vol.91
, pp. 480-485
-
-
Kobayashi, N.1
Maeda, A.2
Horikoshi, S.3
Shirato, I.4
Tomino, Y.5
Ise, M.6
-
10
-
-
0142156124
-
Protein restriction and AST-120 improve lipoprotein lipase and VLDL receptor in focal glomerulosclerosis
-
Sato T, Liang K, Vaziri ND. Protein restriction and AST-120 improve lipoprotein lipase and VLDL receptor in focal glomerulosclerosis. Kidney Int 2003; 64: 1780-1786.
-
(2003)
Kidney Int
, vol.64
, pp. 1780-1786
-
-
Sato, T.1
Liang, K.2
Vaziri, N.D.3
-
11
-
-
0033762864
-
An oral sorbent reduces overload of indoxyl sulphate and gene expression of TGF-β1 in uraemic rat kidneys
-
Miyazaki T, Aoyama I, Ise M, Seo H, Niwa T. An oral sorbent reduces overload of indoxyl sulphate and gene expression of TGF-β1 in uraemic rat kidneys. Nephrol Dial Transplant 2000; 15: 1773-1781.
-
(2000)
Nephrol Dial Transplant
, vol.15
, pp. 1773-1781
-
-
Miyazaki, T.1
Aoyama, I.2
Ise, M.3
Seo, H.4
Niwa, T.5
-
12
-
-
0033936092
-
Oral adsorbent AST-120 ameliorates interstitial fibrosis and transforming growth factor-β1 expression in spontaneously diabetic (OLETF) rats
-
Aoyama I, Shimokata K, Niwa T. Oral adsorbent AST-120 ameliorates interstitial fibrosis and transforming growth factor-β1 expression in spontaneously diabetic (OLETF) rats. Am J Nephrol 2000; 20: 232-241.
-
(2000)
Am J Nephrol
, vol.20
, pp. 232-241
-
-
Aoyama, I.1
Shimokata, K.2
Niwa, T.3
-
13
-
-
2342564944
-
Oral adsorbent AST-120 decreases carotid intima-media thickness and arterial stiffness in patients with chronic renal failure
-
Nakamura T, Kawagoe Y, Matsuda T, Ueda Y, Shimada N, Ebihara I, Koide H. Oral adsorbent AST-120 decreases carotid intima-media thickness and arterial stiffness in patients with chronic renal failure. Kidney Blood Press Res 2004; 27: 121-126.
-
(2004)
Kidney Blood Press Res
, vol.27
, pp. 121-126
-
-
Nakamura, T.1
Kawagoe, Y.2
Matsuda, T.3
Ueda, Y.4
Shimada, N.5
Ebihara, I.6
Koide, H.7
-
14
-
-
33646713442
-
Indoxyl sulfate stimulates proliferation of rat vascular smooth muscle cells
-
Yamamoto H, Tsuruoka S, Ioka T, Ando H, Ito C, Akimoto T, Fujimura A, Asano Y, Kusano E. Indoxyl sulfate stimulates proliferation of rat vascular smooth muscle cells. Kidney Int 2006; 69: 1780-1785.
-
(2006)
Kidney Int
, vol.69
, pp. 1780-1785
-
-
Yamamoto, H.1
Tsuruoka, S.2
Ioka, T.3
Ando, H.4
Ito, C.5
Akimoto, T.6
Fujimura, A.7
Asano, Y.8
Kusano, E.9
-
15
-
-
44449148845
-
Indoxyl sulphate promotes aortic calcification with expression of osteoblast-specific proteins in hypertensive rats
-
Adijiang A, Goto S, Uramoto S, Nishijima F, Niwa T. Indoxyl sulphate promotes aortic calcification with expression of osteoblast-specific proteins in hypertensive rats. Nephrol Dial Transplant 2008; 23 1892-1901.
-
(2008)
Nephrol Dial Transplant
, vol.23
, pp. 1892-1901
-
-
Adijiang, A.1
Goto, S.2
Uramoto, S.3
Nishijima, F.4
Niwa, T.5
-
16
-
-
33645450504
-
Endothelial dysfunction contributes to renal function-associated cardiovascular mortality in a population with mild renal insufficiency: The Hoorn study
-
Stam F, van Guldener C, Becker A, Dekker JM, Heine RJ, Bouter LM, Stehouwer CD. Endothelial dysfunction contributes to renal function-associated cardiovascular mortality in a population with mild renal insufficiency: The Hoorn study. J Am Soc Nephrol 2006; 17 537-545.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 537-545
-
-
Stam, F.1
van Guldener, C.2
Becker, A.3
Dekker, J.M.4
Heine, R.J.5
Bouter, L.M.6
Stehouwer, C.D.7
-
17
-
-
33845729891
-
An oral adsorbent, AST-120, suppresses oxidative stress in uremic rats
-
Nakagawa N, Hasebe N, Sumitomo K, Fujino T, Fukuzawa J, Hirayama T, Kikuchi K. An oral adsorbent, AST-120, suppresses oxidative stress in uremic rats. Am J Nephrol 2006; 26: 455-461.
-
(2006)
Am J Nephrol
, vol.26
, pp. 455-461
-
-
Nakagawa, N.1
Hasebe, N.2
Sumitomo, K.3
Fujino, T.4
Fukuzawa, J.5
Hirayama, T.6
Kikuchi, K.7
-
18
-
-
0242669257
-
Uremic toxins of organic anions up-regulate PAI-1 expression by induction of NF-κB and free radical in proximal tubular cells
-
Motojima M, Hosokawa A, Yamato H, Muraki T, Yoshioka T. Uremic toxins of organic anions up-regulate PAI-1 expression by induction of NF-κB and free radical in proximal tubular cells. Kidney Int 2003; 63: 1671-1680.
-
(2003)
Kidney Int
, vol.63
, pp. 1671-1680
-
-
Motojima, M.1
Hosokawa, A.2
Yamato, H.3
Muraki, T.4
Yoshioka, T.5
-
19
-
-
41849103757
-
Indoxyl sulfate reduces superoxide scavenging activity in the kidneys of normal and uremic rats
-
Owada S, Goto S, Bannai K, Hayashi H, Nishijima F, Niwa T. Indoxyl sulfate reduces superoxide scavenging activity in the kidneys of normal and uremic rats. Am J Nephrol 2008; 28: 446-454.
-
(2008)
Am J Nephrol
, vol.28
, pp. 446-454
-
-
Owada, S.1
Goto, S.2
Bannai, K.3
Hayashi, H.4
Nishijima, F.5
Niwa, T.6
-
20
-
-
34548817877
-
Olmesartan ameliorates renovascular injury and oxidative stress in Zucker obese rats enhanced by dietary protein
-
Namikoshi T, Tomita N, Satoh M, Haruna Y, Kobayashi S, Komai N, Sasaki T, Kashihara N. Olmesartan ameliorates renovascular injury and oxidative stress in Zucker obese rats enhanced by dietary protein. Am J Hypertens 2007; 10: 1085-1091.
-
(2007)
Am J Hypertens
, vol.10
, pp. 1085-1091
-
-
Namikoshi, T.1
Tomita, N.2
Satoh, M.3
Haruna, Y.4
Kobayashi, S.5
Komai, N.6
Sasaki, T.7
Kashihara, N.8
-
21
-
-
34547887314
-
Pioglitazone ameliorates endothelial dysfunction in obese rats with nephropathy
-
Namikoshi T, Satoh M, Tomita N, Haruna Y, Kobayashi S, Komai N, Sasaki T, Kashihara N. Pioglitazone ameliorates endothelial dysfunction in obese rats with nephropathy. Biochem Biophys Res Commun 2007; 361: 835-840.
-
(2007)
Biochem Biophys Res Commun
, vol.361
, pp. 835-840
-
-
Namikoshi, T.1
Satoh, M.2
Tomita, N.3
Haruna, Y.4
Kobayashi, S.5
Komai, N.6
Sasaki, T.7
Kashihara, N.8
-
22
-
-
0027428943
-
Hypertensive rats produced by in vivo introduction of the human renin gene
-
Tomita N, Higaki J, Kaneda Y, Yu H, Morishita R, Mikami H, Ogihara T. Hypertensive rats produced by in vivo introduction of the human renin gene. Circ Res 1993; 73: 898-905.
-
(1993)
Circ Res
, vol.73
, pp. 898-905
-
-
Tomita, N.1
Higaki, J.2
Kaneda, Y.3
Yu, H.4
Morishita, R.5
Mikami, H.6
Ogihara, T.7
-
23
-
-
44649160542
-
Pioglitazone enhances the antihypertensive and renoprotective effects of candesartan in Zucker obese rats fed a high-protein diet
-
Namikoshi T, Tomita N, Satoh M, Haruna Y, Kobayashi S, Komai N, Sasaki T, Kashihara N. Pioglitazone enhances the antihypertensive and renoprotective effects of candesartan in Zucker obese rats fed a high-protein diet. Hypertens Res 2008; 31: 745-755.
-
(2008)
Hypertens Res
, vol.31
, pp. 745-755
-
-
Namikoshi, T.1
Tomita, N.2
Satoh, M.3
Haruna, Y.4
Kobayashi, S.5
Komai, N.6
Sasaki, T.7
Kashihara, N.8
-
24
-
-
36349024339
-
IL-6 deficiency protects against angiotensin II induced endothelial dysfunction and hypertrophy
-
Schrader LI, Kinzenbaw DA, Johnson AW, Faraci FM, Didion SP. IL-6 deficiency protects against angiotensin II induced endothelial dysfunction and hypertrophy. Arterioscler Thromb Vasc Biol 2007; 27: 2576-2581.
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, pp. 2576-2581
-
-
Schrader, L.I.1
Kinzenbaw, D.A.2
Johnson, A.W.3
Faraci, F.M.4
Didion, S.P.5
-
25
-
-
4344683549
-
Homocysteine induced impairment of nitric oxide-dependent vasorelaxation is reversible by the superoxide dismutase mimetic TEMPOL
-
Hucks D, Thuraisingham RC, Raftery MJ, Yaqoob MM. Homocysteine induced impairment of nitric oxide-dependent vasorelaxation is reversible by the superoxide dismutase mimetic TEMPOL. Nephrol Dial Transplant 2004; 19: 1999-2005.
-
(2004)
Nephrol Dial Transplant
, vol.19
, pp. 1999-2005
-
-
Hucks, D.1
Thuraisingham, R.C.2
Raftery, M.J.3
Yaqoob, M.M.4
-
26
-
-
34250163587
-
The uremic solute indoxyl sulfate induces oxidative stress in endothelial cells
-
Dou L, Jourde-Chiche N, Faure V, Cerini C, Berland Y, Dignat-George F, Brunet P. The uremic solute indoxyl sulfate induces oxidative stress in endothelial cells. J Thromb Haemost 2007; 5: 1302-1308.
-
(2007)
J Thromb Haemost
, vol.5
, pp. 1302-1308
-
-
Dou, L.1
Jourde-Chiche, N.2
Faure, V.3
Cerini, C.4
Berland, Y.5
Dignat-George, F.6
Brunet, P.7
-
27
-
-
34249915064
-
An oral adsorbent, AST-120 protects against the progression of oxidative stress by reducing the accumulation of indoxyl sulfate in the systemic circulation in renal failure
-
Shimoishi K, Anraku M, Kitamura K, Tasaki Y, Taguchi K, Hashimoto M, Fukunaga E, Maruyama T, Otagiri M. An oral adsorbent, AST-120 protects against the progression of oxidative stress by reducing the accumulation of indoxyl sulfate in the systemic circulation in renal failure. Pharm Res 2007; 24: 1283-1289.
-
(2007)
Pharm Res
, vol.24
, pp. 1283-1289
-
-
Shimoishi, K.1
Anraku, M.2
Kitamura, K.3
Tasaki, Y.4
Taguchi, K.5
Hashimoto, M.6
Fukunaga, E.7
Maruyama, T.8
Otagiri, M.9
-
28
-
-
34047228310
-
Isohumulones derived from hops ameliorate renal injury via an antioxidative effect in Dahl salt-sensitive rats
-
Namikoshi T, Tomita N, Fujimoto S, Haruna Y, Ohzeki M, Komai N, Sasaki T, Yoshida A, Kashihara N. Isohumulones derived from hops ameliorate renal injury via an antioxidative effect in Dahl salt-sensitive rats. Hypertens Res 2007; 30: 175-184.
-
(2007)
Hypertens Res
, vol.30
, pp. 175-184
-
-
Namikoshi, T.1
Tomita, N.2
Fujimoto, S.3
Haruna, Y.4
Ohzeki, M.5
Komai, N.6
Sasaki, T.7
Yoshida, A.8
Kashihara, N.9
-
29
-
-
1242275127
-
Prevention and reversal of premature endothelial cell senescence and vasculopathy in obesity-induced diabetes by ebselen
-
Brodsky SV, Gealekman O, Chen J, Zhang F, Togashi N, Crabtree M, Gross SS, Nasjletti A, Goligorsky MS. Prevention and reversal of premature endothelial cell senescence and vasculopathy in obesity-induced diabetes by ebselen. Circ Res 2004; 94: 377-384.
-
(2004)
Circ Res
, vol.94
, pp. 377-384
-
-
Brodsky, S.V.1
Gealekman, O.2
Chen, J.3
Zhang, F.4
Togashi, N.5
Crabtree, M.6
Gross, S.S.7
Nasjletti, A.8
Goligorsky, M.S.9
-
30
-
-
41549162787
-
Olmesartan ameliorates progressive glomerular injury in subtotal nephrectomized rats through suppression of superoxide production
-
Fujimoto S, Satoh M, Horike H, Hatta H, Haruna Y, Kobayashi S, Namikoshi T, Arakawa S, Tomita N, Kashihara N. Olmesartan ameliorates progressive glomerular injury in subtotal nephrectomized rats through suppression of superoxide production. Hypertens Res 2008; 31: 305-313.
-
(2008)
Hypertens Res
, vol.31
, pp. 305-313
-
-
Fujimoto, S.1
Satoh, M.2
Horike, H.3
Hatta, H.4
Haruna, Y.5
Kobayashi, S.6
Namikoshi, T.7
Arakawa, S.8
Tomita, N.9
Kashihara, N.10
-
31
-
-
33645780634
-
Endothelial nitric oxide synthase in vascular disease: From marvel to menace
-
Förstermann U, Münzel T. Endothelial nitric oxide synthase in vascular disease: From marvel to menace. Circulation 2006; 113 1708-1714.
-
(2006)
Circulation
, vol.113
, pp. 1708-1714
-
-
Förstermann, U.1
Münzel, T.2
-
32
-
-
0029805172
-
Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and ugly
-
Beckman JS, Koppenol WH. Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. Am J Physiol 1996; 271: C1424-C1437.
-
(1996)
Am J Physiol
, vol.271
-
-
Beckman, J.S.1
Koppenol, W.H.2
-
33
-
-
1642480079
-
The uremic solutes p-cresol and indoxyl sulfate inhibit endothelial proliferation and wound repair
-
Dou L, Bertrand E, Cerini C, Faure V, Sampol J, Vanholder R, Berland Y, Brunet P. The uremic solutes p-cresol and indoxyl sulfate inhibit endothelial proliferation and wound repair. Kidney Int 2004; 65 442-451.
-
(2004)
Kidney Int
, vol.65
, pp. 442-451
-
-
Dou, L.1
Bertrand, E.2
Cerini, C.3
Faure, V.4
Sampol, J.5
Vanholder, R.6
Berland, Y.7
Brunet, P.8
-
34
-
-
33645965258
-
Elevation of circulating endothelial microparticles in patients with chronic renal failure
-
Faure V, Dou L, Sabatier F, Cerini C, Sampol J, Berland Y, Brunet P, Dignat-George F. Elevation of circulating endothelial microparticles in patients with chronic renal failure. J Thromb Haemost 2006; 4 566-573.
-
(2006)
J Thromb Haemost
, vol.4
, pp. 566-573
-
-
Faure, V.1
Dou, L.2
Sabatier, F.3
Cerini, C.4
Sampol, J.5
Berland, Y.6
Brunet, P.7
Dignat-George, F.8
-
35
-
-
33847668826
-
Indoxyl sulphate and atherosclerotic risk factors in hemodialysis patients
-
Taki K, Tsuruta Y, Niwa T. Indoxyl sulphate and atherosclerotic risk factors in hemodialysis patients. Am J Nephrol 2007; 27: 30-35.
-
(2007)
Am J Nephrol
, vol.27
, pp. 30-35
-
-
Taki, K.1
Tsuruta, Y.2
Niwa, T.3
-
36
-
-
25844513144
-
Oxidative stress and nitric oxide deficiency in the kidney: A critical link to hypertension?
-
Wilcox CS. Oxidative stress and nitric oxide deficiency in the kidney: A critical link to hypertension? Am J Physiol Regul Integr Comp Physiol 2005; 289: 913-935.
-
(2005)
Am J Physiol Regul Integr Comp Physiol
, vol.289
, pp. 913-935
-
-
Wilcox, C.S.1
|