Development of a chromosomally integrated metabolite-inducible leu3p-α-IPM "OFF-ON" gene switch

PLoS ONE

Volumn 5, Issue 8, 2010, Pages

  Poulou, Maria ^a   Bell, Donald ^b   Bozonelos, Kostas ^a   Alexiou, Maria ^a,c   Gavalas, Anthony ^b,d   Lovell Badge, Robin ^b   Remboutsika, Eumorphia ^a,b  

^a BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING   (Greece)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^c UNIVERSITY OF ZURICH   (Switzerland)

^d BIOMEDICAL RESEARCH FOUNDATION   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

2 ISOPROPYLMALIC ACID; GREEN FLUORESCENT PROTEIN; MALIC ACID; PROTEIN LEU3P; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ALPHA-ISOPROPYLMALATE; LEU3 PROTEIN, S CEREVISIAE; MALIC ACID DERIVATIVE; SACCHAROMYCES CEREVISIAE PROTEIN; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; BIOSAFETY; BIOSYNTHESIS; CHROMOSOME ADDITION; CONTROLLED STUDY; EMBRYO; EX VIVO STUDY; FEMALE; GENE EXPRESSION REGULATION; GENE EXPRESSION SYSTEM; GENE INDUCTION; GENE REPRESSION; GENE SWITCHING; GENE THERAPY; GENOTYPE; MOUSE; NONHUMAN; PASSIVE TRANSPORT; PROCESS DEVELOPMENT; PROMOTER REGION; REPORTER GENE; SACCHAROMYCES CEREVISIAE; TOXICITY TESTING; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; TRANSGENIC MOUSE; ANIMAL; CHROMOSOME; FIBROBLAST; GENETIC ENGINEERING; GENETICS; MALE; METABOLISM; METHODOLOGY; NUCLEOTIDE SEQUENCE; PREGNANCY;

ANIMALIA; MAMMALIA; MUS MUSCULUS;

ANIMALS; BASE SEQUENCE; CHROMOSOMES, MAMMALIAN; FEMALE; FIBROBLASTS; GENETIC ENGINEERING; MALATES; MALE; MICE; MICE, TRANSGENIC; PREGNANCY; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANS-ACTIVATORS;

EID: 77958003830     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0012488     Document Type: Article

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